Humic acid induces apoptosis in human premyelocytic leukemia HL-60 cells

Life Sciences

Volumn 75, Issue 15, 2004, Pages 1817-1831

  Yang, Hsin Ling ^a   Hseu, You Cheng ^b   Hseu, Yi Ting ^a   Lu, Fung Jou ^c   Lin, Elong ^b   Lai, Jim Shoung ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHUNGTAI INST HLTH SCI TECHNOL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; HL 60 cells; Humic acid

Indexed keywords

CASPASE 3; CYTOCHROME C; DNA FRAGMENT; HUMIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL GROWTH; CELL STRAIN HL 60; CELL VIABILITY; CHROMATIN CONDENSATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DATA ANALYSIS; DRUG ACTIVITY; DRUG SCREENING; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRION; NUCLEOSOME; PROMYELOCYTIC LEUKEMIA; PROTEIN DEGRADATION; PROTEIN SECRETION; TIME;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL DIVISION; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; ELECTROPHORESIS, AGAR GEL; HL-60 CELLS; HUMANS; HUMIC SUBSTANCES; IN SITU NICK-END LABELING; NITRIC OXIDE; PACLITAXEL; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 4043099089     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.02.033     Document Type: Article

References (52)

1. Adams J.M., Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1998;1322-1326
2. Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proceedings of the National Academy of Sciences of the United States of America. 87:1990;1620-1624
3. Bold R.J., Termuhlen P.M., McConkey D.J. Apoptosis, cancer and cancer therapy. Surgical Oncology. 6:1997;133-142
4. Bortner C.D., Oldenburg N.B.E., Cidlowski J.A. The role of DNA fragmentation in apoptosis. Trends in Cell Biology. 5:1995;21-26
5. Burges N.A., Hurst H.M., Walkdenene B. The phenolic constitutents of humic acid and their relationship to the lignin of the plant cover. Geochimica et Cosmochimica Acta. 28:1964;1547-1554
6. Cohen J.J., Duke R.C. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. Journal of Immunology. 132:1984;38-42
7. Cohen G.M., Sun X.M., Snowden R.T., Dinsdale D., Skilleter D.N. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochemical Journal. 286:1992;331-334
8. Choudhry G.G. Humic substances. Part I: structural aspects. Environmental Toxicology and Chemistry. 4:1981;209-259
9. Earnshaw W.C. Nuclear changes in apoptosis. Currrnt Opinion in Cell Biology. 7:1995;337-343
10. Forrest V.J., Kang Y.H., McClain D.E., Robinson D.H., Ramakrishnan N. Oxidative stress-induced apoptosis prevented by Trolox. Free Radical Biology and Medicine. 16:1994;675-684
11. Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. Journal of Cell Biology. 119:1992;493-501
12. Gottlob K., Fulco M., Levrero M., Graessmann A. The Hepatitis B Virus HBx Protein Inhibits Caspase 3 Activity. Journal of Biological Chemistry. 273:1998;33347-33353
13. Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312
14. Guan J., Yang H. Medical value of humic acids. Zhong Yao Cai. 22:1999;430-431
15. Haninen K.I., Klocking R., Helbig B. Synthesis and characterization of humic acid-like polymers. Science of the Total Environment. 62:1987;201-210
16. Hartenstein R. Sludge decomposition and stabilization. Science. 212:1981;743-749
17. Hseu Y.C., Lu F.J., Engelking L.R., Chen C.L., Chen Y.H., Yang H.L. Humic acid-induced echinocyte transformation in human erythrocytes: characterization of morphological changes and determination of the mechanism of damage. Journal of Toxicology and Environmental Health part A. 60:2000;215-230
18. Hseu Y.C., Wang S.Y., Chen H.Y., Yang H.L. Humic Acid Induces Apoptosis in Human Endothelial Cells. Toxicology and Applied Pharmacology. 182:2002;34-43
19. Hseu Y.C., Chang W.C., Wang S.Y., Chen H.Y., Yang H.L. Humic acid induces the generation of nitric oxide in human umbilical vein endothelial cells: Stimulation of nitric oxide synthase during cell injury. Free Radical Biology and Medicine. 32:2002;619-629
20. Huie R.E., Padmaja S. The reaction of no with superoxide. Free Radical Research Communications. 18:1993;195-199
21. Jacobson M.D., Burne J.F., Raff M.C. Mechanisms of programmed cell death and Bcl-2 protection. Biochemical Society Transactions. 22:1994;600-602
22. Jacobson M.D., Raff M.C. Programmed cell death and Bcl-2 protection in very low oxygen. Nature. 374:1995;814-816
23. Jezierski A., Czechowski F., Jerzykiewicz M., Chen Y., Drozd J. Electron Paramagnetic resonance (EPR) studies on stable and transient radicals in bhumic acids from compost, soil, peat and brown coal. Spectrochimica Acta part A-Molecular and Spectroscopy. 56:2000;379-385
24. Kamesaki H. Mechanisms involved in chemotherapy-induced apoptosis and their implications in cancer chemotherapy. International Journal of Hematology. 68:1998;29-43
25. Keyser P., Pujar B.G., Eaton R.W., Ribbons D.W. Biodegradation of the pthalates and their esters by bacteria. Environmental Health Perspectives. 18:1976;159-166
26. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature. 371:1994;346-347
27. Liang H.J., Tsai C.L., Chen P.Q., Lu F.J. Oxidative injury induced by synthetic humic acid polymer and monomer in cultured rabbit articular chondrocytes. Life Sciences. 65:1999;1163-1173
28. Liang H.J., Tsai C.L., Lu F.J. Oxidative stress induced by humic acid solvent extraction fraction in cultured rabbit articular chondrocytes. Journal of Toxicology and Environmrnt Health part A. 54:1998;477-489
29. Lu F.J., Yamamura Y., Yamauchi H. Studies on fluorescent compounds in water of a well in Blackfoot disease endemic areas in Taiwan: Humic substances. Journal Formosan Medical Association. 87:1988;66-75
30. Lu F.J. Fluorescent humic substances and blackfoot disease in Taiwan. Applied Organometallic Chemistry. 4:1990;191-193
31. 2+ mediated endonuclease activation. Science. 242:1988;256-259
32. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43
33. Noronha-Dutra A.A., Epperlein M.M., Woolf N. Effect of cigarette smoking on cultured human endothelial cells. Cardiovascular Research. 27:1993;774-778
34. Nosseri C., Coppola S., Ghibelli L. Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis. Experimental Cell Research. 212:1994;367-373
35. Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619
36. Rao L., White E. Bcl-2 and the ICE family of apoptotic regulators: making a connection. Current Opinion in Genetics and Development. 7:1997;52-58
37. Rowinsky E.K., Burke P.J., Karp J.E., Tucker R.W., Ettinger D.S., Donoehower R.C. Phase I and pharmacodynamic study of taxol in refractory acute leukemias. Cancer Research. 49:1989;4640-4647
38. Schulze-Osthoff K., Walczak H., Droge W., Krammer P.H. Cell nucleus and DNA fragmentation are not required for apoptosis. Journal of Cell Biology. 127:1994;15-20
39. Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809
40. Tseng T.H., Wang C.J., Kao E.S., Chu C.Y. Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes. Chemistry Biological Interaction. 101:1996;137-148
41. Tseng T.H., Hsu J.D., Lo M.H., Chou F.P., Huang C.L., Chu C.Y., Wang C.J. Inhibitory effect of Hibiscus protocatechuic acid on tumor promotion in miuse skin. Cancer Letter. 126:1998;199-207
42. Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316
43. Ueda N., Shah S.V. Role of intracellular calcium in hydrogen peroxide-induced renal tubular cell injury. Americal Journal of Physiology. 263:1992;f214-f221
44. Ungureanu-Longrois D., Balligand J.L., Okada I., Simmons W.W., Kobzik L., Lowenstein C.J., Kunkel S.L., Michel T., Kelly R.A., Smith T.W. Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture. Circulation Research. 77:1995;486-493
45. Visser S.A. Effect of humic substances on mitochondrial respiration and oxidative phosphorylation. Science of the Total Environment. 62:1987;347-354
46. Wani M.C., Yaylor H.L., Wall M.E., Coggon P., McPhail A.T. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. Journal American Chemistry Society. 93:1971;2325-2327
47. Wyllie A.H., Kerr J.F., Currie A.R. Cell death: the significance of apoptosis. International Review of Cytology. 68:1980;251-306
48. Wyllie A.H. Apoptosis: cell death in tissue regulation. Journal of Pathology. 153:1987;313-316
49. Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., Cai J., Peng T.I., Jones D.P., Wang X. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 275:1997;1129-1132
50. Yang H.L., Lu F.J., Wang S.L., Chiu H.C. Humic acid induces expression of tissue factor by cultured endothelial cells: Regulation by cytosolic calcium and pprotein kinase C. Thrombosis and Haemostasis. 71:1994;325-330
51. Yang H.L., Chiu H.C., Lu F.J. Effects of humic acid on the viability and coagulant properties of human umbilical vein endothelial cells. American Journal of Hematology. 51:1996;200-206
52. Yang H.L., Hseu Y.C., Lu F.J., Tsai H.D. Humic acid reduces protein C-activating cofactor activity of thrombomodulin of human umbilical vein endothelial cells. British Journal Haematology. 101:1998;16-23