Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving erk1/2-dependent NFATc4 phosphorylation

Journal of Biological Chemistry

Volumn 283, Issue 7, 2008, Pages 4200-4209

  Chandrasekar, Bysani ^a,b,d   Patel, Devang N ^b   Mummidi, Srinivas ^a,b   Kim, Jae Woo ^c   Clark, Robert A ^a,b   Valente, Anthony J ^b  

^a SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c Yonsei University College of Medicine   (South Korea)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; CHEMICAL REACTIONS; DNA; ENZYME ACTIVITY; GENES; NUCLEIC ACIDS; ORGANIC ACIDS; PHOSPHORYLATION; RNA; SIGNAL TRANSDUCTION;

ADIPOCYTES; ADIPONECTIN; CORONARY ARTERY DISEASES; CYTOKINE; DISEASE PROGRESSIONS; DNA BINDINGS; IN-VIVO; INHIBITORY EFFECTS; INSULIN RESISTANCES; INVERSE CORRELATIONS; INVERSE RELATIONSHIPS; METABOLIC SYNDROMES; MRNA EXPRESSIONS; NUCLEAR TRANSLOCATIONS; PATHOLOGICAL CONDITIONS; PRETREATMENT; SIGNAL TRANSDUCTION PATHWAYS; SMALL INTERFERENCE RNAS;

ELECTRIC LOAD MANAGEMENT;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADIPONECTIN; INTERLEUKIN 18; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NFAT; NFATC4 PROTEIN, MOUSE; PRIMER DNA;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL DEATH; CELL STRAIN 3T3; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; REPORTER GENE;

3T3-L1 CELLS; ADIPOCYTES; ADIPONECTIN; ANIMALS; BASE SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, REPORTER; INTERLEUKIN-18; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 42949122235     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708142200     Document Type: Article

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