A focus on high-content cytometry

Cytometry Part A

Volumn 73, Issue 5, 2008, Pages 381-383

  Tárnok, Attila ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; AUTOMATION; BIOINFORMATICS; CELL MATURATION; CELL ORGANELLE; CELL PROLIFERATION; CELL STRUCTURE; COMPUTER PROGRAM; CYTOMETRY; DIAGNOSTIC TEST; EDITORIAL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HEALTH CARE COST; HIGH THROUGHPUT SCREENING; MEASUREMENT; PHENOTYPE; PRIORITY JOURNAL; RELIABILITY; STANDARDIZATION; SYSTEMS BIOLOGY; TECHNOLOGY;

DRUG DESIGN; FLOW CYTOMETRY; HUMANS; IMAGE CYTOMETRY; SYSTEMS BIOLOGY;

EID: 42949083139     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.20571     Document Type: Editorial

References (46)

1. Kitano H. Computational systems biology. Nature 2002;420:206-210.
2. Tárnok A, Bocsi J, Brockhoff G. Cytomics - Importance of multimodal analysis of cell function and proliferation in oncology. Cell Prolif 2006;39:495-505.
3. Valet G. Cytomics as a new potential for drug discovery. Drug Discov Today 2006;11:785-791.
4. Valet G. Predictive medicine by cytomics: Potential and challenges. J Biol Regul Homeost Agents 2002;16:164-167.
5. Dove A. Screening for content - The evolution of high throughput. Nat Biotechnol 2003;21:859-864.
6. Keefer S, Zock J.Approaching high content screening and analysis: Practical advice for users. In: Haney SA, editor. High Content Screening: Science, Techniques and Applications, Chapter 1. Hoboken: Wiley; 2008. p 4.
7. Van Osta P, Ver Donck K, Bols L, Geysen J Cytomics and drug discovery. Cytometry A 2006;69A:117-118.
8. Smith PJ, Khan IA, Errington RJ. Cytomics and drug development. Cytometry A 2007;71A:349-351.
9. Valet G. Cytomics, the human cytome project and systems biology: Top-down resolution of the molecular biocomplexity of organisms by single cell analysis. Cell Prolif 2005;38:171-174.
10. Hood L, Heath JR, Phelps ME, Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science 2004;306:640-643.
11. Burdine L, Kodadek T. Target identification in chemical genetics: The (often) missing link. Chem Biol 2004;11:593-597.
12. Eggert US, Mitchison TJ. Small molecule screening by imaging. Curr Opin Chem Biol 2006;10:232-237.
13. Edwards BS, Oprea T, Prossnitz ER, Sklar LA. Flow cytometry for high-throughput, high-content screening. Curr Opin Chem Biol 2004;8:392-398.
14. Sklar LA, Carter MB, Edwards BS. Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening. Curr Opin Pharmacol 2007;7:527-534.
15. Peluso J, Tabaka-Moreira H, Taquet N, Dumont S, Muller CD, Reimund JM. Can flow cytometry play a part in cell based high-content screening? Cytometry A 2007;71A:901-904.
16. Chattopadhyay PK, Price DA, Harper TF, Betts MR, Yu J, Gostick E, Perfetto SP, Goepfert P, Koup RA, De Rosa SC, Bruchez MP, Roederer M. Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry. Nat Med 2006;12:972-977.
17. Tárnok A. Slide-based cytometry for cytomics - A minireview. Cytometry A 2006;69A:555-562.
18. Mittag A, Lenz D, Gerstner AO, Tárnok A. Hyperchromatic cytometry principles for cytomics using slide based cytometry. Cytometry A 2006;69A:691-703.
19. Mosch B, Morawski M, Mittag A, Lenz D, Tarnok A, Arendt T. Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease. J Neurosci 2007;27:6859-6867.
20. Ecker RC, Tárnok A. Cytomics goes 3D: Towards tissomics. Cytometry A 2005;65A:1-3.
21. Kriete A, Boyce K, Love B. System-wide analysis of hepatotoxicological responses: Tissomics is key. Cytometry A 2006;69A:612-619.
22. Tarnok A. The new Cytometry Part A. Cytometry A 2007;71A:533-535.
23. Tárnok A. A focus on automated recognition. Cytometry A 2007;71A:769-770.
24. Tárnok A. A focus on cell proliferation and death. Cytometry A 2007;71A:637-638.
25. Dennis MK, Bowles HJC, MacKenzie DA, Burchiel SW, Edwards BS, Sklar LA, Prossnitz ER, Thompson TA. A multifunctional androgen receptor screening assay using the high-throughput hypercyt® flow cytometry system. Cytometry A 2008;73A:390-399 (this issue).
26. Beck V, Reiter E, Jungbauer A. Androgen receptor transactivation assay using green fluorescent protein as a reporter. Anal Biochem 2008;373:263-271.
27. Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression. Anal Biochem 2008;375:237-248.
28. Damveld RA, Franken A, Arentshorst M, Punt PJ, Klis FM, van den Hondel CA, Ram AFA. Novel screening method for cell wall mutants in Aspergillus niger identifies UDP-galactopyranose mutase as an important protein in fungal cell wall biosynthesis. Genetics 2008;178:873-881.
29. McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF Ottinger J, Oxford C, Evans TG, Asmuth DM. Nine-color flow cytometry for accurate measurement of T-cell subsets and cytokine responses. Part I: Panel design by an empiric approach. Cytometry A 2008;73A:400-410 (this issue).
30. McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Li J, Beckett L, Shacklett BL, Evans TG, Asmuth DM. Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms. Cytometry A 2008;73A:411-420 (this issue).
31. Perfetto SP, Chattopadhyay PK, Roederer M. Seventeen-colour flow cytometry: Unravelling the immune system. Nat Rev Immunol 2004;4:648-655.
32. Lambert C, Cristina I, Christian G. Enumeration of peripheral lymphocyte subsets using 6 vs. 4 color staining: A clinical evaluation of a new flowcytometer. Cytometry B Clin Cytom 2006;70B:29-38.
33. Ashman M, Sachdeva N, Davila L, Scott G, Mitchell C, Cintron L, Rathore M, Asthana D. Influence of 4- and 6-color flow cytometers and acquisition/analysis softwares on the determination of lymphocyte subsets in HIV infection. Cytometry B Clin Cytom 2007;72B:380-386.
34. De Rosa SC, Brenchley JM, Roederer M. Beyond six colors: A new era in flow cytometry. Nat Med 2003;9:112-117.
35. Roederer M. How many events is enough? Are you positive? Cytometry A 2008;73A:384-385 (this issue).
36. Kim KH, Ragan T, Previte MJ, Bahlmann K, Harley BA, Wiktor-Brown DM, Stitt MS, Hendricks CA, Almeida KH, Engelward BP, So PT. Three-dimensional tissue cytometer based on high-speed multiphoton microscopy. Cytometry A 2007;71A:991-1002.
37. Tárnok A, Gerstner AO. Clinical applications of laser scanning cytometry. Cytometry 2002;50:133-143.
38. Paar C, Paster W; Stockinger H, Schütz GJ, Sonnleitner M, Sonnleitner A. High throughput FRET screening of the plasma membrane based on TIRFM. Cytometry A 2008;73A:442-450 (this issue).
39. Nagy P, Szöllösi J. Commentary; Seeing through protein complexes by high-throughput FRET. Cytometry A 2008;73A:388-389 (this issue).
40. Boedigheimer MJ, Ferbas J. Mixture modeling approach to flow cytometry data. Cytometry A 2008;73A:421-429 (this issue).
41. Rogers WT, Moser AR, Holyst HA, Bantly A, Mohler ER III, Scangas G, Moore JS. Cytometric fingerprinting: Quantitative characterization of multivariate distributions. Cytometry A 2008;73A:430-441 (this issue).
42. Pattanapanyasat K, Shain H, Prasertsilpa V, Noulsri E, Lerdwana S, Eksaengsri A Low cost CD4 enumeration using generic monoclonal antibody reagents and a two-color user-defined MultiSET protocol. Cytometry B Clin Cytom 2006;70B:355-360.
43. Pedreira CE, Costa ES, Arroyo ME, Almeida J, Orfao A. A multidimensional classification approach for the automated analysis of flow cytometry data. IEEE Trans Biomed Eng 2008;55:1155-1162.
44. Lockett SJ, O'Rand M, Rinehart CA, Kaufman DG, Herman B, Jacobson K. Automated fluorescence image cytometry. DNA quantification and detection of chlamydial infections. Anal Quant Cytol Histol 1991;13:27-44.
45. Lin G, Chawla MK, Olson K, Barnes CA, Guzowski JF, Bjornsson C, Shain W, Roysam B. A multi-model approach to simultaneous segmentation and classification of heterogeneous populations of cell nuclei in 3D confocal microscope images. Cytometry A 2007;71A:724-736.
46. Gudla PR, Collins J, Nandy K, Meaburn KJ, Misteli T, Lockett SJ. A high-throughput system for segmenting nuclei using multiscale techniques. Cytometry A 200S;73A:451-466 (this issue).