Salivary cortisol, dehydroepiandrosterone, and testosterone interrelationships in healthy young males: A pilot study with implications for studies of aggressive behavior

Psychiatry Research

Volumn 159, Issue 1-2, 2008, Pages 67-76

  Brown, Gerald L ^a   McGarvey, Elizabeth L ^a   Shirtcliff, Elizabeth A ^b   Keller, Adrienne ^a   Granger, Douglas A ^c   Flavin, Kara ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Aggression; Normal; Saliva steroids; Young males

Indexed keywords

HYDROCORTISONE; PRASTERONE; TESTOSTERONE;

ADULT; AGGRESSION; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PILOT STUDY; PRIORITY JOURNAL; SALIVA ANALYSIS; SALIVA LEVEL; STATE-TRAIT ANGER EXPRESSION INVENTORY;

AGGRESSION; DEHYDROEPIANDROSTERONE; HUMANS; HYDROCORTISONE; MALE; PILOT PROJECTS; SALIVA; TESTOSTERONE;

EID: 42749093685     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psychres.2007.06.012     Document Type: Article

References (51)

1. Adler L., Wedekind D., Pilz J., Weniger G., and Huether G. Endocrine correlates of personality traits: a comparison between emotionally stable and emotionally labile healthy young men. Neuropsychobiology 35 (1997) 205-210
2. Bahrke M.S., Yesalis III C.E., and Wright J.E. Psychological and behavioural effects of endogenous testosterone levels and anabolic-androgenic steroids among males: a review. Sports Medicine 10 (1990) 303-337
3. Banks T., and Dabbs Jr. J.M. Salivary testosterone and cortisol in a delinquent and violent urban subculture. Journal of Social Psychology 136 (1996) 49-56
4. Bergman B., and Brismar B. Characteristics of imprisoned wife-beaters. Forensic Science International 65 (1994) 157-167
5. Bergman B., and Brismar B. Hormone levels and personality traits in abusive and suicidal male alcoholics. Alcoholism, Clinical and Experimental Research 18 (1994) 311-316
6. Booth, A., Granger, D.A., Mazur, A., Kivlighan, K.T., in press. Testosterone and social behavior: An empirically-based conceptual integration. Social Forces.
7. Brown G.L., and Linnoila M.I. CSF serotonin metabolite (5-HIAA) studies in depression, impulsivity, and violence. Journal of Clinical Psychiatry 5 (1990) 31-41 (suppl)
8. Brown G.L., Goodwin F.K., Ballenger J.C., Goyer P.F., and Major L.F. Aggression in humans correlates with cerebrospinal fluid amine metabolites. Psychiatry Research 1 (1979) 131-139
9. Brown G.L., Goodwin F.K., Ballenger J.C., and Goyer P.F. Cerebrospinal fluid amine metabolites and cyclic nucleotides in human aggression. Psychopharmacology Bulletin 17 (1981) 63-65
10. Cicchetti D., and Rogosch F.A. The impact of child maltreatment and psychopathology on neuroendocrine functioning. Development and Psychopathology 13 (2001) 783-804
11. Cooper J.R., Bloom R.E., and Roth R.H. Chapter 10. Serotonin, histamine and adenosine. In: The Biochemical Basis of Neuropharmacology. Eighth edition (2003), Oxford University Press, New York 301-312
12. Cotrufo P., Monteleone P., d'Istria M., Fuschino A., Serino I., and Maj M. Aggressive behavioral characteristics and endogenous hormones in women with bulimia nervosa. Neuropsychobiology 42 (2000) 58-61
13. Dabbs Jr. J.M., Jurkovic G.J., and Frady R.L. Salivary testosterone and cortisol among late adolescent male offenders. Journal of Abnormal Child Psychology 19 (1991) 469-478
14. Dmitrieva T.N., Oades R.D., Hauffa B.P., and Eggers C. Dehydroepiandrosterone sulphate and corticotropin levels are high in young male patients with conduct disorder: comparisons for growth factors, thyroid and gonadal hormones. Neuropsychobiology 43 (2001) 134-140
15. Dolan M., Anderson I.M., and Deakin J.F. Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders. The British Journal of Psychiatry 178 (2001) 352-359
16. Erickson K., Drevets W., and Schulkin J. Glucocorticoid regulation of diverse cognitive functions in normal and pathological emotional states. Neuroscience Biobehavioral Reviews 27 (2003) 233-246
17. Gerra G., Avanzini P., Zaimovic A., Fertonani G., Caccavari R., Delsignore R., Gardini F., Talarico E., Lecchini R., Maestri D., and Brambilla F. Neurotransmitter and endocrine modulation of aggressive behavior and its components in normal humans. Behavioral Brain Research 81 (1996) 19-24
18. Gerra G., Zaimovic A., Avanzini P., Chittolini B., Giucastro G., Caccavari R., Palladino M., Maestri D., Monica C., Delsignore R., and Brambilla F. Neurotransmitter-neuroendocrine responses to experimentally induced aggression in humans: influence of personality variable. Psychiatry Research 66 (1997) 33-43
19. Gerra G., Zaimovic A., Giucastro G., Folli F., Maestri D., Tessoni A., Avanzini P., Caccavari R., Bernasconi S., and Brambilla F. Neurotransmitter-hormonal responses to psychological stress in peripubertal subjects: relationship to aggressive behavior. Life Sciences 62 (1998) 617-625
20. Granger D.A., and Kivlighan K.T. Integrating biological, behavioral, and social levels of analysis in early child development research: progress, problems, and prospects. Child Development 74 (2003) 1058-1063
21. Granger D.A., Schwartz E.B., Booth A., Curran M., and Zakaria D. Assessing dehydroepiandrosterone in saliva: a simple radioimmunoassay for use in studies of children, adolescents and adults. Pychoneuroendocrinology 24 (1999) 567-579
22. Granger D.A., Shirtcliff E.A., Zahn-Waxler C., Usher B.A., Klimes-Dougan B., and Hastings P.D. Salivary testosterone diurnal variation and psychopathology in adolescent males and females: individual differences and developmental effects. Development and Psychopathology 15 (2003) 431-449
23. Granger D.A., Shirtcliff E.A., Booth A., Kivlighan K.T., and Schwartz E.B. The "trouble" with salivary testosterone. Psychoneuroendocrinology 29 (2004) 1229-1240
24. Guyton A., and Hall J.E. Textbook of Medical Physiology. Ninth edition (1996), W.B. Saunders, Philadelphia
25. Halpern C.T., Udry J.R., Campbell B., and Suchindran C. Relationships between aggression and pubertal increases in testosterone: a panel analysis of adolescent males. Social Biology 40 (1993) 8-24
26. Higley J.D., Mehlman P.T., Poland R.E., Taub D.M., Vickers J., Suomi S.J., and Linnoila M. CSF testosterone and 5-HIAA correlate with different types of aggressive behaviors. Biological Psychiatry 40 (1996) 1067-1082
27. Hruschka D.J., Kohrt B.A., and Worthman C.M. Estimating between- and within-individual variation in cortisol levels using multilevel models. Psychoneuroendocrinology 30 (2005) 698-714
28. Kudielka B.M., Broderick J.E., and Kirschbaum C. Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects. Psychosomatic Medicine 65 (2003) 313-319
29. Lindman R.E., Aromaki A.S., and Eriksson C.J. Sober-state cortisol as a predictor of drunken violence. Alcohol and Alcoholism 32 (1997) 621-626
30. Linnoila M., Virkkunen M., Scheinin M., Nuutila A., Rimon R., and Goodwin F.K. Low CSF can differentiates impulsive from non-impulsive violent behavior. Life Sciences 33 (1983) 2609-2614
31. Mazur A. Biosocial models of deviant behavior among male army veterans. Biological Psychology 41 (1995) 271-293
32. Mazur A., and Booth A. Testosterone and dominance in men. Behavioral and Brain Sciences 21 (1998) 363-397
33. McBurnett K., Lahey B.B., Rathouz P.J., and Loeber R. Low salivary cortisol and persistent aggression in boys referred for disruptive behavior. Archives of General Psychiatry 57 (2000) 38-43
34. Morgan C.A., Southwick S., Hazlett G., Rasmusson A., Hoyt G., Zimolo Z., and Charnery D. Relationships among plasma Dehydroepiandrosterone Sulfate and cortisol levels, symptoms of dissociation, and objective performance in humans exposed to acute stress. Archives of General Psychiatry 61 (2004) 819-825
35. Navarro M.A., Juan L., Bonnin M.R., and Villabona C. Salivary testosterone: relationship to total and free testosterone in serum. Clinical Chemistry 32 (1986) 231-232
36. Rantonen P.J., Penttila I., Meurman J.H., Savolainen K., Narvanen S., and Helenius T. Growth hormone and cortisol in serum and saliva. Acta Odontologica Scandinavica 58 (2000) 299-303
37. Reith E., Breidenbach B., and Lorenc M. Textbook of Anatomy and Physiology. Twenty-second edition (1978), McGraw-Hill, New York
38. Riad-Fahmy D., Read G.F., Walker R.F., and Griffiths K. Steroids in saliva for assessing endocrine function. Endocrine Reviews 3 (1982) 367-395
39. Sapolsky R.M., Romero L.M., and Munck A.U. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Reviews 21 (2000) 55-89
40. Scerbo A.S., and Kolko D.J. Salivary testosterone and cortisol in disruptive children: relationship to aggressive, hyperactive, and internalizing behaviors. Journal of the American Academy of Child and Adolescent Psychiatry 33 (1994) 1174-1184
41. Schaal B., Tremblay R.E., Soussignan R., and Susman E.J. Male testosterone linked to high social dominance but low physical aggression in early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry 35 (1996) 1322-1330
42. Sephton S.E., Sapolsky R.M., Kraemer H.C., and Spiegel D. Diurnal cortisol rhythm as a predictor of breast cancer survival. Journal of the National Cancer Institute 92 (2000) 994-1000
43. Shirtcliff E.A., Granger D.A., Booth A., and Johnson D. Low salivary cortisol levels and externalizing behavior problems in youth. Development and Psychopathology 17 1 (2005) 167-184
44. Spielberger C.D. State-Trait Anger Expression Inventory: Professional Manual (1996), Psychological Assessment Resources, Odessa, Florida
45. Umeda T., Hiramatsu R., Iwaoka T., Shimada T., Miura F., and Sato T. Use of saliva for monitoring unbound free cortisol levels in serum. Clinica Chimica Acta 110 (1981) 245-253
46. van Goozen S.H., Matthys W., Cohen-Kettenis P.T., Thijssen J.H., and van Engeland H. Adrenal androgens and aggression in conduct disorder prepubertal boys and normal controls. Biological Psychiatry 43 (1998) 156-158
47. van Goozen S.H., van den Ban E., Matthys W., Cohen-Kettenis P.T., Thijssen J.H., and van Engeland H. Increased adrenal androgen functioning in children with oppositional defiant disorder: a comparison with psychiatric and normal controls. Journal of American Academy of Adolescent Psychiatry 39 (2000) 1446-1451
48. Vining R.F., McGinley R.A., and Symons R.G. Hormones in saliva: mode of entry and consequent implications for clinical interpretation. Clinical Chemistry 29 (1983) 1752-1756
49. Virkkunen M., Rawlings R., Tokola R., Poland R.E., Guidotti A., Nemeroff C., Bissette G., Kalogeras K., Karonen S.L., and Linnoila M. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry 51 (1994) 20-27
50. Virkkunen M. Urinary free cortisol secretion in habitually violent offenders. Acta Psychiatrica Scandinavica 72 (1985) 40-44
51. Von der P.B., Sarkola T., Seppa K., and Eriksson C.J. Testosterone, 5 alpha-dihydrotestosterone and cortisol in men with and without alcohol-related aggression. Journal of Studies on Alcohol 63 (2002) 518-526