Molecular determinants of ligand specificity in family 11 carbohydrate binding modules - An NMR, X-ray crystallography and computational chemistry approach

FEBS Journal

Volumn 275, Issue 10, 2008, Pages 2524-2535

  Viegas, Aldino ^a   Brás, Natércia F ^b   Cerqueira, Nuno M F S A ^b   Fernandes, Pedro Alexandrino ^b   Prates, José A M ^c   Fontes, Carlos M G A ^c   Bruix, Marta ^d   Romão, Maria João ^a   Carvalho, Ana Luísa ^a   Ramos, Maria João ^b,e   Macedo, Anjos L ^a   Cabrita, Eurico J ^a  

^a UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^b Campus Universitário de Santiago   (Portugal)

^c FACULDADE DE MEDICINA VETERINÁRIA   (Portugal)

^d INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^e UNIVERSITY OF PORTO   (Portugal)

Author keywords

Cellulosome; Clostridium thermocellum; CtCBM11; STD NMR molecular modelling; X ray crystallography

Indexed keywords

BINDING PROTEIN; CARBOHYDRATE BINDING MODULE 11; CARBOHYDRATE DERIVATIVE; CELLOBIOSE; CELLOHEXAOSE; CELLOTETRAOSE;

ARTICLE; BINDING AFFINITY; CLOSTRIDIUM THERMOCELLUM; CONTROLLED STUDY; CRYSTAL STRUCTURE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BINDING SITES; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CELLOBIOSE; CELLULASE; CELLULOSE; CLOSTRIDIUM THERMOCELLUM; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOSACCHARIDES; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; TETROSES;

CLOSTRIDIUM THERMOCELLUM;

EID: 42649116746     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06401.x     Document Type: Article

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