The cellulosome: An exocellular, multiprotein complex specialized in cellulose degradation

Critical Reviews in Biochemistry and Molecular Biology

Volumn 31, Issue 3, 1996, Pages 201-236

  Béguin, Pierre ^a   Lemaire, Marc ^a,b  

^a CNRS   (France)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

cellulase; Clostridium thermocellum; docking domain; protein protein interaction; scaffolding protein

Indexed keywords

CELLULASE; CELLULOSE; HYDROLASE;

AMINO ACID COMPOSITION; CELL MEMBRANE; CELL ORGANELLE; CELL SURFACE; CLOSTRIDIUM THERMOCELLUM; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; RECEPTOR BINDING; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0030002212     PISSN: 10409238     EISSN: None     Source Type: Journal    
DOI: 10.3109/10409239609106584     Document Type: Review

References (22)

1. Aït, N., Creuzet, N., and Forget, P. 1979. Partial purification of cellulase from Clostridium thermocellum. J. Gen. Microbiol. 113: 399-402.
2. Ali, B. R. S., Remaniec, M. P. M., Hazlewood, G. P., and Freedman, R. B. 1995a. Characterization of the subunits in an apparently homogeneous subpopulation of Clostridium thermocellum cellulosomes. Enzyme Microb. Technol. 17: 705-711.
3. Ali, B. R. S., Zhou, L., Graves, F., Freedman, R. B., Black, G. W., Gilbert, H. J., and Hazlewood, G. P. 1995b. Cellulases and hemicellulases of the anaerobic fungus Piromyces constitute a multiprotein cellulose-binding complex and are encoded by multigene families. FEMS Microbiol. Lett. 125: 15-22.
4. Alzari, P. M., Souchon, H., and Dominguez, R. 1996. The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum. Structure. 4: 265-275.
5. Antranikian, G., Herzberg, C., Mayer, F., and Gottschalk, G. 1987. Changes in the cell envelope structure of Clostridium sp. strain EM1 during massive production of α-amylase and pullulanase. FEMS Microbiol. Lett. 41: 193-197.
6. Bagnara-Tardif, C., Gaudin, C., Belaich, A., Hoest, P., Citard, P., and Belaich, J.-P. 1992. Sequence analysis of a gene cluster encoding cellulases from Clostridium celulolyticum. Gene. 119: 17-28.
7. Bayer, E. A., Kenig, R., and Lamed, R. 1983. Adherence of Clostridium thermocellum to cellulose. J. Bacteriol. 156: 818-827.
8. Bayer, E. A., Setter, E., and Lamed, R. 1985. Organization and distribution of the cellulosome in Clostridium thermocellum. J. Bacteriol. 163: 552-559.
9. Bayer, E. A. and Lamed, R. 1986. Ultrastructure of the cell surface cellulosome of Clostridium thermocellum and its interaction with cellulose. J. Bacteriol. 167: 828-836.
10. Tokatlidis, K., Dhurjati, P., and Béguin, P. 1993. Properties conferred on Clostridium thermocellum endoglucanase CelC by grafting the duplicated segment of endoglucanase CelD. Protein Eng. 6: 947-952.
11. Tomme, P., van Tilbeurgh, H., Pettersson, G., van Damme, J., Vandekerckhove, J., Knowles, J., Teeri, T., and Claeyssens, M. 1988. Studies of the cellulolytic system of Trichoderma reesei QM 9414. Eur. J. Biochem. 170: 575-581.
12. Tuka, K., Zverlov, V. V., Bumazkin, B. K., Velikodvorskaya, G. A., and Strongin, A. Y. 1990. Cloning and expression of Clostridium thermocellum genes coding for thermostable exoglucanases (cellobiohydrolases) in Escherichia coli cells. Biochem. Biophys. Res. Commun. 169: 1055-1060.
13. Tuka, K., Zverlov, V. V., and Velikodvorskaya, G. A. 1992. Synergism between Clostridium thermocellum cellulases cloned in Escherichia coli. Appl. Biochem. Biotechnol. 37: 201-207.
14. van Tilbeurgh, H., Claeyssens, M., and De Bruyne, C. K. 1982. The use of 4-methylumbelliferyl and other chromophoric glycosides in the study of cellulolytic enzymes. FEBS Lett. 149: 152-156.
15. van Tilbeurgh, H., Tomme, P., Claeyssens, M., Bhikhabhai, R., and Pettersson, G. 1986. Limited proteolysis of the cellobiohydrolase I from Trichoderma reesei. FEBS Lett. 204: 223-227.
16. Wakil, S. J. 1989. Fatty acid synthetase, a proficient multifunctional enzyme. Biochemistry 28: 4523-4530.
17. Wu, J. H. D., Orme-Johnson, W. H., and Demain, A. L. 1988. Two components of an extracellular protein aggregate of Clostridium thermocellum together degrade crystalline cellulose. Biochemistry 27: 1703-1709.
18. Xue, G. P., Gobius, K. S., and Orpin, C. G. 1992a. A novel polysaccharide hydrolase cDNA (celD) from Neocallimastix patriciarum encoding three multi-functional catalytic domains with high endoglucanase, cellobiohydrolase, and xylanase activity. J. Gen. Microbiol. 138: 2397-2403.
19. Xue, G. P., Orpin, C. G., Gobius, K. S., Aylward, J. H., and Simpson, G. D. 1992b. Cloning and expression of multiple cellulase cDNAs from the anaerobic fungus Neocallimastix patriciarum. J. Gen. Microbiol. 138: 1413-1420.
20. Yaron, S., Morag, E., Bayer, E. A., Lamed, R., and Shoham, Y. 1995. Expression, purification and subunit-binding properties of cohesins 2 and 3 of the Clostridium thermocellum cellulosome. FEBS Lett. 360: 121-124.
21. Zhou, L. Q., Xue, G. P., Orpin, C. G., Gilbert, H. J., and Hazlewood, G. P. 1994. Intronless celB from the anaerobic fungus Neocallimastix patriciarum encodes a modular family A endoglucanase. Biochem. J. 297: 359-364.
22. Zverlov, V. V. and Velikodvorskaya, G. A. 1990. Cloning the Clostridium thermocellum thermostable laminarinase gene in Escherichia coli - the properties of the enzyme thus produced. Biotechnol. Lett. 12: 811-816.