Hesperetin attenuates the highly reducing sugar-triggered inhibition of osteoblast differentiation

Cell Biology and Toxicology

Volumn 24, Issue 3, 2008, Pages 225-231

  Choi, Eun Mi ^a   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

Author keywords

2 Deoxy d ribose; Hesperetin; Osteoblastic MC3T3 E1 cells; Oxidative stress

Indexed keywords

2 DEOXYRIBOSE; ALKALINE PHOSPHATASE; ANTIOXIDANT; CARBONYL DERIVATIVE; CELL PROTEIN; COLLAGEN; HESPERETIN; MALONALDEHYDE; SUGAR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; BONE DISEASE; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRAIN 3T3; DIABETES MELLITUS; DIET SUPPLEMENTATION; ENZYME ACTIVITY; MOUSE; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

3T3 CELLS; ANIMALS; CARBOHYDRATES; CELL DIFFERENTIATION; HESPERIDIN; LIPID PEROXIDATION; MICE; OSTEOBLASTS;

EID: 42549148447     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-007-9031-0     Document Type: Article

References (32)

1. Ayrton A, Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica. 2001;31:469-97.
2. Balint E, Szabo P, Marshall CF, Sprague SM. Glucose-induced inhibition of in vitro bone mineralization. Bone (NY). 2001;28:21-8.
3. Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications. A new perspective on an old paradigm. Diabetes. 1999;48:1-9.
4. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry. 1976;72:248-54.
5. Bunn HF, Higgins PJ. Reaction of monosaccharides with proteins: possible evolutionary significance. Science. 1981;213:222-4.
6. Clarkson MR, Murphy M, Gupta S, Lambe T, Mackenzie HS, Godson C, Martin F, Brady HR. High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly. J Biol Chem. 2002;277:9707-12.
7. Crespy V, Morand C, Besson C, Cotelle N, Vezin H, Demigne C, et al. The splanchnic metabolism of flavonoids highly differed according to the nature of the compound. Am J Physiol Gastrointest Liver Physiol. 2003;284:G980-8.
8. Domon S, Shimokawa H, Yamaguchi S, Kunimichi S. Temporal and spatial mRNA expression of bone sialoprotein and type I collagen during rodent tooth movement. Eur J Orthod. 2001;23:339-48.
9. Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 2002;23:599-622.
10. Horcajada-Molteni M, Chanteranne B, Lebecque P, Davicco MJ, Coxam V, Young A, et al. Amylin and bone metabolism in streptozotocin-induced diabetic rats. J Bone Miner Res. 2001;16:958-65.
11. Hunt JV, Dean RT, Wolff SP. Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing. Biochem J. 1988;256:205-12.
12. Ihara Y, Toyokuni S, Uchida K, Odaka H, Tanaka T, Ikeda H, et al. Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes. 1999;48:927-32.
13. Kanno S, Anuradha CD, Hirano S. Localization of zinc after in vitro mineralization in osteoblastic cells. Biol Trace Elem Res. 2001;83:39-47.
14. Kletsas D, Barbieri D, Stathakos D, Botti B, Bergamini S, Tomasi A, Monti D, et al. The highly reducing sugar 2-deoxy-d-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeletal disruption. Biochem Biophys Res Commun. 1998;243:416-25.
15. Koh G, Suh KS, Chon S, Oh S, Woo JT, Kim SW, et al. Elevated cAMP level attenuates 2-deoxy-d-ribose-induced oxidative damage in pancreatic β-cells. Arch Biochem Biophys. 2005;438:70-9.
16. Levine RL. Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radic Biol Med. 2002;32:790-6.
17. Lien YH, Stern R, Fu CCC, Siegel RC. Inhibition of collagen fibril formation in vitro and subsequent cross-linking by glucose. Science. 1984;255:1489-91.
18. Lowry OH, Roberts NR, Wu M-L, Hixon WS, Crawford EJ. The quantitative histochemistry of brain. II. Enzyme measurements. J Biol Chem. 1954;207:19-37.
19. Matsuoka T, Kajimoto Y, Watada H, Kaneto H, Kishimoto M, Umayahara Y, et al. Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells. J Clin Invest. 1997;99:144-50.
20. Monnier VM. Nonenzymatic glycosylation, the Maillard reaction and the aging process. J Gerontol. 1990;45:B105-18.
21. Narisawa S, Frohlander N, Millan JL. Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia. Dev Dyn. 1997;208:432-46.
22. Noda M. Current topics in pharmacological research on bone metabolism: regulation of bone mass by the function of endogenous modulators of bone morphogenetic protein in adult stage. J Pharmacol Sci. 2006;100:211-4.
23. Ozgocmen S, Kaya H, Fadillioglu E, Aydogan R, Yilmaz Z. Role of antioxidant systems, lipid peroxidation, and nitric oxide in postmenopausal osteoporosis. Mol Cell Biochem. 2007;295:45-52.
24. Robertson RP, Olson LK, Zhang HJ. Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene. Diabetes. 1994;43:1085-9.
25. Robertson RP, Tsai P, Little SA, Zhang HJ, Walseth TF. Receptor-mediated adenylate cyclase-coupled mechanism for PGE2 inhibition of insulin secretion in HIT cells. Diabetes. 1987;36:1047-53.
26. Seeman E. Reduced bone formation and increased bone resorption: rational targets for the treatment of osteoporosis. Osteoporos Int. 2003;14 (Suppl. 3):S2-8.
27. Silberberg M, Morand C, Mathevon T, Besson C, Manach C, Scalbert A, et al. The bioavailability of polyphenols is highly governed by the capacity of the intestine and of the liver to secrete conjugated metabolites. Eur J Nutr. 2006;45(2):88-96.
28. Stein GS, Lian JB, Owen TA. Relationship of cell growth to the regulation of tissue-specific gene expression during progressive osteoblast differentiation. The FASEB Journal. 1990;4:111-23.
29. Terada M, Inaba M, Yano Y, Hasuma T, Nishizawa Y, Morii H, et al. Growth-inhibitory effect of a high glucose concentration on osteoblast-like cells. Bone. 1998;22:17-23.
30. Vissers MC, Winterbourn CC. Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl. Arch Biochem Biophys. 1991;285:53-9.
31. Witko-Sarsat V, Friedlander M, Capeillere-Blandin C, Nguyen-Khoa T, Nguyen AT, Zingraff J. Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int. 1996;49:1304-13.
32. Wolff SP, Dean RT. Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes. Biochem J. 1987;245:243-50.