Prognostic value of protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1) in gastric cancer

Anticancer Research

Volumn 28, Issue 2 A, 2008, Pages 847-854

  Fujimoto, Daisuke ^a   Hirono, Yasuo ^a   Goi, Takanori ^a   Katayama, Kanji ^a   Yamaguchi, Akio ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Gastric cancer; Immunohistochemistry; Matrix metalloproteinase 1 (MMP 1); Prognostic factor; Protease activated receptor 1 (PAR 1)

Indexed keywords

INTERSTITIAL COLLAGENASE; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; PROTEINASE ACTIVATED RECEPTOR 1;

ARTICLE; CANCER GROWTH; CANCER INVASION; DISSEMINATED CANCER; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MULTIVARIATE ANALYSIS; PATHOLOGY; PERITONEUM METASTASIS; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS; STOMACH CARCINOMA;

HUMANS; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 1; PROGNOSIS; RECEPTOR, PAR-1; STOMACH NEOPLASMS; SURVIVAL ANALYSIS;

EID: 42549146507     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Coughlin SR: Thrombin signaling and protease-activated receptors. Nature 407: 258-264, 2000.
2. Vu TKH, Hung DT, Wheaton IV and Coughlin SR: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor action. Cell 64: 1057-1068, 1991.
3. Kuliopulos A, Covic L, Seeley SK, Sheridan PJ, Helin J and Costello CE: Plasmin desensitization of the PAR1 thrombin receptor: kinetics, sites of truncation, and implications for thrombolytic therapy. Biochemistry 38: 4572-4585, 1999.
4. Riewald M, Kravchenko VV, Petorovan RJ, O'Brien PJ, Brass LF, Ulevitch RJ and Ruf W: Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor1. Blood 97: 3109-3116, 2001.
5. Riewald M, Petrovan RJ, Donner A, Muller BM and Ruf W: Activation of endothelial cell protease receptor1 b the protein C pathway. Science 296: 1880-1882, 2002.
6. Seeley S, Covic L, Jacques SL, Sudmeier J, Baleja JD and Kuliopulos A: Structural basis for thrombin activation of a protease-activated receptor: Inhibition of intramolecular liganding. Chem Biol 10: 1033-1041, 2003.
7. Wojtukiewicz MZ, Tang DG, Ben-Josef E, Renaud C, Walz DA and Honn KV: Solid tumor cells express functional 'tethered ligand' thrombin receptor. Cancer Res 55: 698-704, 1995.
8. Rudroff C, Schafberg H, Nowak G, Weinel R, Scheele J and Kaufmann R: Characterization of functional thrombin receptor in human pancreatic tumor cells (MIA PACA-2). Pancreas 16: 189-194, 1998.
9. Kaufmann R, Schaberg H, Rudroff C and Nowak G: Thrombin receptor activation results in calcium signaling and protein kinase C-dependent stimulation of DNA synthesis in Hep-2g laryngeal carcinoma cells. Cancer 80: 2068-2074, 1997.
10. Even-Ram S, Uziely B, Cohen P, Grisaru-Granovsky S, Maoz M, Ginzburg Y, Reich R, Vlodavsky I and Bar-Shavit R: Thrombin receptor overexpression in malignant and physiological invasion processes. Nat Med 4: 909-914, 1998.
11. Henrikson KP, Salazar SL, Fenton JW 2nd and Pentecost BT: Role of thrombin receptor in breast cancer invasiveness. Br J Cancer 79: 401-406, 1999.
12. Boire A, Covic L, Agarwal A, Jacques S, Sherifi S and Kuliopulos A: PAR1 is a Matrix metalloproteinase-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 120: 303-313, 2005.
13. Nelson AR, Fingleton B, Rothenberg ML and Matrisian LM: Matrix metalloproteinases: biologic activity and clinical implications. J Clini Oncol 18: 1135-1149, 2000.
14. Collins HM, Morris TM and Watson SA: Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinase and membrane type-1 matrix metalloproteinase. Br J Cancer 84: 1664-1670, 2001.
15. D'Errico A, Garbisa S, Liotta LA, Castronovo V, Stetler-Stevenson WG and Grigioni WF: Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression. Mod Pathol 4: 239-246, 1991.
16. Grigioni WF, D'errico A, Fortunato C, Fiorentino M, Mancini AM and Stetler-Stevenson WG: Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane. Mod Pathol 7: 220-225, 1994.
17. Sakurai Y, Otani Y, Kameyama K, Igarashi N, Kubota T, Kumai K and Kitajima M: The role of stromal cells in the expression of interstitial collagenase (matrix metalloproteinase-1) in the invasion of gastric cancer. J Surg Oncol 66: 168-172, 1997.
18. Japanese Gastric Cancer Association. Japanese Classification of Gastric Carcinoma -2nd English edition. Gastric Cancer 1: 10-24, 1998.
19. Migita T, Sato E, Saito K, Mizoi T, Shiiba K, Matsuno S, Nagura H and Ohtani H: Differing expression of MMPs-1 and -9 and urokinase receptor between diffuse- and intestinal-type gastric carcinoma. Int J Cancer 84: 74-79, 1999.
20. Fujimoto D, Hirono Y, Goi T, Katayama K, Hirose K and Yamaguchi A: Expression of protease activated receptor-2 (PAR-2) in gastric cancer J Surg Oncol 93: 139-144, 2006.
21. Gregiore M and Lieubeau B: The role of fibroblasts in tumor behavior. Cancer Metastasis Rev 14: 339-350, 1995.
22. O'Meara RAQ: Coagulative properties of cancers. Ir J Med Sci 394: 474-479, 1958.
23. Hou L, Kapas S, Cruchley AT, Macey MG, Harriott P, Chinni C, Stone SR and Howells G: Immunolocaliozation of protease-activated receptor-2 in skin: receptor activation stimulates interleukin-8 secretion by keratinocytes in vitro. Immunology 94: 356-362, 1998.
24. Koshikawa N, Hasegawa S, Nagashima Y, Mitsuhashi K, Tsubota Y, Miyata S, Miyagi Y, Yasumitsu H and Miyazaki K: Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse. Am J Pathol 153: 937-944, 1998.
25. Koshikawa N, Nagashima Y, Miyagi Y, Mizushima H, Yanoma S, Yasumitsu H and Miyazaki K: Expression of trypsin in vascular endothelial cells. FEBS Lett 499: 442-448, 1997.
26. Zucker S, Mirza H, Conner CE, Lorenz AF, Drews MH, Bahou WF and Jesty J: Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation. Int J Cancer 75: 780-786, 1998.
27. Yamamoto A, Yano S, Shiraga M, Ogawa H, Goto H, Miki T, Zhang H and Sone S: A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses prognosis of lung micrometastasis of MMP-expressing tumor cells in nude mice. Int J Cancer 103: 822-828, 2003.