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Volumn 80, Issue 11, 1997, Pages 2068-2074

Thrombin receptor activation results in calcium signaling and protein kinase C-dependent stimulation of DNA synthesis in HEp-2g laryngeal carcinoma cells

Author keywords

thrombin; HEp 2g; Protein kinase C; Thrombin receptor activating peptide

Indexed keywords

BISINDOLYLMALEIMIDE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE;

EID: 0030691950     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19971201)80:11<2068::AID-CNCR5>3.0.CO;2-T     Document Type: Article
Times cited : (30)

References (24)
  • 1
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TKH, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991; 64:1057-68.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.H.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 2
    • 0029143923 scopus 로고
    • Mechanism of thrombin receptor agonist specifity. Chimeric receptors and complementary mutations identify an agonist recognition site
    • Nanevicz T, Ishii M, Wang L, Chen M, Chen J, Turck CW, et al. Mechanism of thrombin receptor agonist specifity. Chimeric receptors and complementary mutations identify an agonist recognition site. J Biol Chem 1995;270:21619-25.
    • (1995) J Biol Chem , vol.270 , pp. 21619-21625
    • Nanevicz, T.1    Ishii, M.2    Wang, L.3    Chen, M.4    Chen, J.5    Turck, C.W.6
  • 3
    • 0002906957 scopus 로고
    • Platelet membrane proteins: Composition and receptor function
    • Gordon J, editor. Amsterdam: Elsevier/North Holland
    • Berndt M, Philipps D. Platelet membrane proteins: composition and receptor function. In: Gordon J, editor. Platelets in biology and pathology. Amsterdam: Elsevier/North Holland, 1981:43-7.
    • (1981) Platelets in Biology and Pathology , pp. 43-47
    • Berndt, M.1    Philipps, D.2
  • 4
    • 0019305915 scopus 로고
    • Thrombin active-site regions required for fibroblast receptor binding and initiation of cell division
    • Glenn K, Carney D, Fenton J, Cunningham D. Thrombin active-site regions required for fibroblast receptor binding and initiation of cell division. J Biol Chem 1980;255:6609-16.
    • (1980) J Biol Chem , vol.255 , pp. 6609-6616
    • Glenn, K.1    Carney, D.2    Fenton, J.3    Cunningham, D.4
  • 5
    • 0020570701 scopus 로고
    • Monocyte chemotaxis: Stimulation by specific exosite region in thrombin
    • Bar-Shavit R, Mudd M, Wilner G, Mann K, Fenton JWII. Monocyte chemotaxis: stimulation by specific exosite region in thrombin. Science 1983;220:728-31.
    • (1983) Science , vol.220 , pp. 728-731
    • Bar-Shavit, R.1    Mudd, M.2    Wilner, G.3    Mann, K.4    Fenton, J.W.I.I.5
  • 6
    • 0023178323 scopus 로고
    • Small cell carcinoma of the lung: Interaction with the blood coagulation mechanism and treatment with anticoagulants
    • Zacharski LR. Small cell carcinoma of the lung: interaction with the blood coagulation mechanism and treatment with anticoagulants. Onkologie 1987;10:264-70.
    • (1987) Onkologie , vol.10 , pp. 264-270
    • Zacharski, L.R.1
  • 7
    • 0024311763 scopus 로고
    • A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leucemia group B
    • Chahinian AP. A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leucemia group B. J Clin Oncol 1989;7:993-1002.
    • (1989) J Clin Oncol , vol.7 , pp. 993-1002
    • Chahinian, A.P.1
  • 8
    • 0026684801 scopus 로고
    • Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo
    • Nierodzik ML, Kajumo LR, Karpatkin S. Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo. Cancer Res 1992;52:3267-72.
    • (1992) Cancer Res , vol.52 , pp. 3267-3272
    • Nierodzik, M.L.1    Kajumo, L.R.2    Karpatkin, S.3
  • 10
    • 0027183889 scopus 로고
    • Transcription of genes encoding granulocyte-macrophage colony-stimulating factor, interleukin 3, and interleukin 6 receptors and lack of proliferative response to exogenous cytokines in nonhematopoietic human malignant cell lines
    • Guillaume T, Sekhavat M, Rubinstein DB, Hamadan O, Syman ML. Transcription of genes encoding granulocyte-macrophage colony-stimulating factor, interleukin 3, and interleukin 6 receptors and lack of proliferative response to exogenous cytokines in nonhematopoietic human malignant cell lines. Cancer Res 1993;53:3139-44.
    • (1993) Cancer Res , vol.53 , pp. 3139-3144
    • Guillaume, T.1    Sekhavat, M.2    Rubinstein, D.B.3    Hamadan, O.4    Syman, M.L.5
  • 11
    • 0028219965 scopus 로고
    • A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in ; human cells
    • Hemmi S, Bohni R, Stark G, Di Marco F, Aguet M. A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in ; human cells. Cell 1994;76:803-10.
    • (1994) Cell , vol.76 , pp. 803-810
    • Hemmi, S.1    Bohni, R.2    Stark, G.3    Di Marco, F.4    Aguet, M.5
  • 12
    • 0028879357 scopus 로고
    • Tenascin C induction by the diffusible factor epidermal growth factor in stromal-epithelial interactions
    • Sakai T, Ohta M, Furukawa Y, Saga Y, Aizawa S, Kawakatsu H, et al. Tenascin C induction by the diffusible factor epidermal growth factor in stromal-epithelial interactions. J Cell Physiol 1995;165:18-29.
    • (1995) J Cell Physiol , vol.165 , pp. 18-29
    • Sakai, T.1    Ohta, M.2    Furukawa, Y.3    Saga, Y.4    Aizawa, S.5    Kawakatsu, H.6
  • 14
    • 0019061918 scopus 로고
    • LIGAND: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ, Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 1980;107:220-39.
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 15
    • 0024488636 scopus 로고
    • Fluorescence probes of cell signaling
    • Tsien RY. Fluorescence probes of cell signaling. Annu Rev Neurosci 1989;12:227-53.
    • (1989) Annu Rev Neurosci , vol.12 , pp. 227-253
    • Tsien, R.Y.1
  • 16
    • 0025145757 scopus 로고
    • Protein kinase C inhibition by calmodulin and its fragments
    • Krüger H, Schröder W, Buchner K, Hucho F. Protein kinase C inhibition by calmodulin and its fragments. J Protein Chem 1990;9:467-73.
    • (1990) J Protein Chem , vol.9 , pp. 467-473
    • Krüger, H.1    Schröder, W.2    Buchner, K.3    Hucho, F.4
  • 17
    • 0024547829 scopus 로고
    • Kinases and phosphatases in T-cell activation
    • Alexander DR, Cantrell DA. Kinases and phosphatases in T-cell activation. Immunol Today 1989;10:200-5.
    • (1989) Immunol Today , vol.10 , pp. 200-205
    • Alexander, D.R.1    Cantrell, D.A.2
  • 18
    • 0024457676 scopus 로고
    • The mechanism of protein kinase C activation
    • Huang KP. The mechanism of protein kinase C activation. Trends Neurosci 1989;12:425-32.
    • (1989) Trends Neurosci , vol.12 , pp. 425-432
    • Kp, H.1
  • 19
    • 0027488033 scopus 로고
    • Immunologic analysis of the cloned thrombin receptor activation mechanism: Evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment
    • Norton KJ, Scarborough RM, Kutok JL, Escobedo M-A, Nannizzi L, Coller BS. Immunologic analysis of the cloned thrombin receptor activation mechanism: evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment. Blood 1993;82:2125-36.
    • (1993) Blood , vol.82 , pp. 2125-2136
    • Norton, K.J.1    Scarborough, R.M.2    Kutok, J.L.3    Escobedo, M.-A.4    Nannizzi, L.5    Coller, B.S.6
  • 21
    • 0022870417 scopus 로고
    • The glycocalicin portion of platelet glycoprotein Ib express both high and moderate affinity receptor sites for thrombin
    • Harmon JT, Jamieson GA. The glycocalicin portion of platelet glycoprotein Ib express both high and moderate affinity receptor sites for thrombin. J Biol Chem 1986;261:3184-8.
    • (1986) J Biol Chem , vol.261 , pp. 3184-3188
    • Harmon, J.T.1    Jamieson, G.A.2
  • 22
    • 0020063793 scopus 로고
    • Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C
    • Esmon NL, Owen WG, Esmon CT. Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C. J Biol Chem 1982;257:859-64.
    • (1982) J Biol Chem , vol.257 , pp. 859-864
    • Esmon, N.L.1    Owen, W.G.2    Esmon, C.T.3
  • 23
    • 0018932068 scopus 로고
    • Protease nexin: A cellular component that links thrombin and plasminogen activator and mediates their binding to cells
    • Baker JB, Low DA, Simmer RL, Cunningham DD. Protease nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Cell 1980;21:37-45.
    • (1980) Cell , vol.21 , pp. 37-45
    • Baker, J.B.1    Low, D.A.2    Simmer, R.L.3    Cunningham, D.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.