Determination of lipophilicity of α-(4-phenylpiperazine) derivatives of N-benzylamides using chromatographic and computational methods

Biomedical Chromatography

Volumn 22, Issue 4, 2008, Pages 428-432

  Bajda, Marek ^a   Bucki, Adam ^a   Szlek, Jakub ^a   Szwaczkiewicz, Marta ^a   Świerczek, Maciej ^a   Malawska, Barbara ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Calculated partition coefficient; Derivatives of 4 phenylpiperazine; Lipophilicity; N benzylamides; Retention parameters RM0 capacity factors; RP TLC and HPLC

Indexed keywords

C (PROGRAMMING LANGUAGE); HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; THIN LAYER CHROMATOGRAPHY;

BENZYLAMIDE; CALCULATED PARTITION COEFFICIENTS; CAPACITY FACTORS; DERIVATIVE OF 4-PHENYLPIPERAZINE; LIPOPHILICITY; N-BENZYLAMIDE; RETENTION PARAMETER RM0 CAPACITY FACTOR; REVERSED-PHASE HIGH PERFORMANCE; REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY; REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY AND HPLC;

ACETONITRILE;

ACETONITRILE; ALPHA (4 PHENYLPIPERAZINE) DERIVATIVE; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CALCULATION; COMPUTER PROGRAM; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG DETERMINATION; DRUG STRUCTURE; INTERMETHOD COMPARISON; LIPOPHILICITY; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STATISTICAL SIGNIFICANCE; THIN LAYER CHROMATOGRAPHY;

EID: 42549131866     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.951     Document Type: Article

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