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Volumn 59, Issue 5, 2008, Pages 243-252

Prognostic modelling in ischaemic stroke study, additional value of genetic characteristics: Rationale and design

Author keywords

Antithrombotics; Genetics; Haemorrhages; Ischaemic stroke, prognosis; Pharmacogenetics; Secondary prevention

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALPHA2 INTEGRIN; BETA1 INTEGRIN; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8A; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOCHROME P450 2C9; FIBRINOGEN; FIBRINOGEN BETA; FIBRINOGEN GAMMA; GLYCOPROTEIN IB ALPHA; GLYCOPROTEIN IIIA; GLYCOPROTEIN VI; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTHROMBIN; THROMBOPLASTIN; UNCLASSIFIED DRUG; VITAMIN K EPOXIDE REDUCTASE COMPLEX 1; VON WILLEBRAND FACTOR;

EID: 42449141136     PISSN: 00143022     EISSN: None     Source Type: Journal    
DOI: 10.1159/000115638     Document Type: Article
Times cited : (2)

References (77)
  • 1
    • 0030890074 scopus 로고    scopus 로고
    • Trial Study Group: We need stronger predictors of major vascular events in patients with a recent transient ischemic attack or nondisabling stroke
    • Dippel DW, Koudstaal PJ; Dutch TIA Trial Study Group: We need stronger predictors of major vascular events in patients with a recent transient ischemic attack or nondisabling stroke. Stroke 1997;28:774-776.
    • (1997) Stroke , vol.28 , pp. 774-776
    • Dippel, D.W.1    Koudstaal, P.J.2    Dutch, T.I.A.3
  • 2
    • 33744748927 scopus 로고    scopus 로고
    • Gene-gene and gene-environment interplay represent specific susceptibility for different types of ischaemic stroke and leukoaraiosis
    • Szolnoki Z, Melegh B: Gene-gene and gene-environment interplay represent specific susceptibility for different types of ischaemic stroke and leukoaraiosis. Curr Med Chem 2006;13:1627-1634.
    • (2006) Curr Med Chem , vol.13 , pp. 1627-1634
    • Szolnoki, Z.1    Melegh, B.2
  • 3
    • 0033843087 scopus 로고    scopus 로고
    • Genetics and ischaemic stroke
    • Hassan A, Markus HS: Genetics and ischaemic stroke. Brain 2000;123:1784-1812.
    • (2000) Brain , vol.123 , pp. 1784-1812
    • Hassan, A.1    Markus, H.S.2
  • 4
    • 0029101493 scopus 로고
    • Trial Study Group: Recurrent stroke after transient ischaemic attack or minor ischaemic stroke: does the distinction between small and large vessel disease remain true to type?
    • Kappelle LJ, van Latum JC, van Swieten JC, Algra A, Koudstaal PJ, van Gijn J; Dutch TIA Trial Study Group: Recurrent stroke after transient ischaemic attack or minor ischaemic stroke: does the distinction between small and large vessel disease remain true to type? J Neurol Neurosurg Psychiatry 1995;59:127-131.
    • (1995) J Neurol Neurosurg Psychiatry , vol.59 , pp. 127-131
    • Kappelle, L.J.1    van Latum, J.C.2    van Swieten, J.C.3    Algra, A.4    Koudstaal, P.J.5    van Gijn, J.6    Dutch, T.I.A.7
  • 5
    • 0037367576 scopus 로고    scopus 로고
    • Stroke subtype and mortality: A follow-up study in 998 patients with a first cerebral infarct
    • De Jong G, Van Raak L, Kessels F, Lodder J: Stroke subtype and mortality: a follow-up study in 998 patients with a first cerebral infarct. J Clin Epidemiol 2003;56:262-268.
    • (2003) J Clin Epidemiol , vol.56 , pp. 262-268
    • De Jong, G.1    Van Raak, L.2    Kessels, F.3    Lodder, J.4
  • 6
    • 34247892454 scopus 로고    scopus 로고
    • Carotid intimamedia thickness is different in large- and small-vessel ischemic stroke: The SMART study
    • Pruissen DM, Gerritsen SA, Prinsen TJ, Dijk JM, Kappelle LJ, Algra A: Carotid intimamedia thickness is different in large- and small-vessel ischemic stroke: the SMART study. Stroke 2007;38:1371-1373.
    • (2007) Stroke , vol.38 , pp. 1371-1373
    • Pruissen, D.M.1    Gerritsen, S.A.2    Prinsen, T.J.3    Dijk, J.M.4    Kappelle, L.J.5    Algra, A.6
  • 7
    • 0034651014 scopus 로고    scopus 로고
    • The association between the Val34Leu polymorphism in the factor XIII gene and brain infarction
    • Elbaz A, Poirier O, Canaple S, Chedru F, Cambien F, Amarenco P: The association between the Val34Leu polymorphism in the factor XIII gene and brain infarction. Blood 2000;95:586-591.
    • (2000) Blood , vol.95 , pp. 586-591
    • Elbaz, A.1    Poirier, O.2    Canaple, S.3    Chedru, F.4    Cambien, F.5    Amarenco, P.6
  • 10
    • 28444481323 scopus 로고    scopus 로고
    • A novel polymorphism in the factor XIII B-subunit (His95Arg): Relationship to subunit dissociation and venous thrombosis
    • Komanasin N, Catto AJ, Futers TS, van Hylckama V, Rosendaal FR, Ariens RA: A novel polymorphism in the factor XIII B-subunit (His95Arg): relationship to subunit dissociation and venous thrombosis. J Thromb Haemost 2005;3:2487-2496.
    • (2005) J Thromb Haemost , vol.3 , pp. 2487-2496
    • Komanasin, N.1    Catto, A.J.2    Futers, T.S.3    van Hylckama, V.4    Rosendaal, F.R.5    Ariens, R.A.6
  • 12
    • 0035760865 scopus 로고    scopus 로고
    • Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes
    • O'Connor FF, Shields DC, Fitzgerald A, Cannon CP, Braunwald E, Fitzgerald DJ: Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes. Blood 2001;98:3256-3260.
    • (2001) Blood , vol.98 , pp. 3256-3260
    • O'Connor, F.F.1    Shields, D.C.2    Fitzgerald, A.3    Cannon, C.P.4    Braunwald, E.5    Fitzgerald, D.J.6
  • 14
    • 0036403874 scopus 로고    scopus 로고
    • Evaluation of the interactions of common genetic mutations in stroke subtypes
    • Szolnoki Z, Somogyvari F, Kondacs A, Szabo M, Fodor L: Evaluation of the interactions of common genetic mutations in stroke subtypes. J Neurol 2002;249:1391-1397.
    • (2002) J Neurol , vol.249 , pp. 1391-1397
    • Szolnoki, Z.1    Somogyvari, F.2    Kondacs, A.3    Szabo, M.4    Fodor, L.5
  • 15
    • 0036015994 scopus 로고    scopus 로고
    • Arterial wall thickness and the risk of recurrent ischemic events in carriers of the prothrombin G20210A mutation with clinical manifestations of atherosclerosis
    • Gerdes VE, ten Cate H, de Groot E, Kwa VI, Prins MH, Reitsma PH, Buller HR, Brandjes DP: Arterial wall thickness and the risk of recurrent ischemic events in carriers of the prothrombin G20210A mutation with clinical manifestations of atherosclerosis. Atherosclerosis 2002;163:135-140.
    • (2002) Atherosclerosis , vol.163 , pp. 135-140
    • Gerdes, V.E.1    ten Cate, H.2    de Groot, E.3    Kwa, V.I.4    Prins, M.H.5    Reitsma, P.H.6    Buller, H.R.7    Brandjes, D.P.8
  • 16
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • Wald DS, Law M, Morris JK: Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002;325:1202.
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 19
    • 0037986620 scopus 로고    scopus 로고
    • Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: Effects on fibrin structure and function
    • Standeven KF, Grant PJ, Carter AM, Scheiner T, Weisel JW, Ariens RA: Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: effects on fibrin structure and function. Circulation 2003;107:2326-2330.
    • (2003) Circulation , vol.107 , pp. 2326-2330
    • Standeven, K.F.1    Grant, P.J.2    Carter, A.M.3    Scheiner, T.4    Weisel, J.W.5    Ariens, R.A.6
  • 20
    • 28844473918 scopus 로고    scopus 로고
    • Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma levels
    • Uitte de Willige S, De Visser MC, Houwing-Duistermaat JJ, Rosendaal FR, Vos HL, Bertina RM: Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma levels. Blood 2005;106:4176-4183.
    • (2005) Blood , vol.106 , pp. 4176-4183
    • Uitte de Willige, S.1    De Visser, M.C.2    Houwing-Duistermaat, J.J.3    Rosendaal, F.R.4    Vos, H.L.5    Bertina, R.M.6
  • 23
    • 1342302813 scopus 로고    scopus 로고
    • Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease
    • Smith FB, Connor JM, Lee AJ, Cooke A, Lowe GD, Rumley A, Fowkes FG: Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease. Thromb Res 2003;112:209-216.
    • (2003) Thromb Res , vol.112 , pp. 209-216
    • Smith, F.B.1    Connor, J.M.2    Lee, A.J.3    Cooke, A.4    Lowe, G.D.5    Rumley, A.6    Fowkes, F.G.7
  • 28
    • 23244465368 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of stroke: Replicated findings in two nested case-control studies based on independent cohorts
    • Wiklund PG, Nilsson L, Ardnor SN, Eriksson P, Johansson L, Stegmayr B, Hamsten A, Holmberg D, Asplund K: Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of stroke: replicated findings in two nested case-control studies based on independent cohorts. Stroke 2005;36:1661-1665.
    • (2005) Stroke , vol.36 , pp. 1661-1665
    • Wiklund, P.G.1    Nilsson, L.2    Ardnor, S.N.3    Eriksson, P.4    Johansson, L.5    Stegmayr, B.6    Hamsten, A.7    Holmberg, D.8    Asplund, K.9
  • 30
    • 0035894635 scopus 로고    scopus 로고
    • The Sma I polymorphism in the von Willebrand factor gene associated with acute ischemic stroke
    • Dai K, Gao W, Ruan C: The Sma I polymorphism in the von Willebrand factor gene associated with acute ischemic stroke. Thromb Res 2001;104:389-395.
    • (2001) Thromb Res , vol.104 , pp. 389-395
    • Dai, K.1    Gao, W.2    Ruan, C.3
  • 33
    • 4043152900 scopus 로고    scopus 로고
    • Platelet membrane collagen receptor glycoprotein VI polymorphism is associated with coronary thrombosis and fatal myocardial infarction in middle-aged men
    • Ollikainen E, Mikkelsson J, Perola M, Penttila A, Karhunen PJ: Platelet membrane collagen receptor glycoprotein VI polymorphism is associated with coronary thrombosis and fatal myocardial infarction in middle-aged men. Atherosclerosis 2004;176:95-99.
    • (2004) Atherosclerosis , vol.176 , pp. 95-99
    • Ollikainen, E.1    Mikkelsson, J.2    Perola, M.3    Penttila, A.4    Karhunen, P.J.5
  • 38
    • 0035385932 scopus 로고    scopus 로고
    • Advances in molecular genetics and pathology of cerebrovascular disorders
    • Kalaria RN: Advances in molecular genetics and pathology of cerebrovascular disorders. Trends Neurosci 2001;24:392-400.
    • (2001) Trends Neurosci , vol.24 , pp. 392-400
    • Kalaria, R.N.1
  • 40
    • 0029089247 scopus 로고
    • Clinical spectrum of CADASIL: A study of 7 families - cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    • Chabriat H, Vahedi K, Iba-Zizen MT, Joutel A, Nibbio A, Nagy TG, Krebs MO, Julien J, Dubois B, Ducrocq X: Clinical spectrum of CADASIL: a study of 7 families - cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Lancet 1995;346:934-939.
    • (1995) Lancet , vol.346 , pp. 934-939
    • Chabriat, H.1    Vahedi, K.2    Iba-Zizen, M.T.3    Joutel, A.4    Nibbio, A.5    Nagy, T.G.6    Krebs, M.O.7    Julien, J.8    Dubois, B.9    Ducrocq, X.10
  • 43
    • 33750997615 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: Dual effect of MTHFR polymorphisms C677T and A1298C
    • Sazci A, Ergul E, Tuncer N, Akpinar G, Kara I: Methylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: dual effect of MTHFR polymorphisms C677T and A1298C. Brain Res Bull 2006;71:45-50.
    • (2006) Brain Res Bull , vol.71 , pp. 45-50
    • Sazci, A.1    Ergul, E.2    Tuncer, N.3    Akpinar, G.4    Kara, I.5
  • 44
    • 33750116139 scopus 로고    scopus 로고
    • Oral anticoagulants versus antiplatelet therapy for preventing further vascular events after transient ischaemic attack or minor stroke of presumed arterial origin
    • CD001342
    • Algra A, De Schryver EL, van Gijn J, Kappelle LJ, Koudstaal PJ: Oral anticoagulants versus antiplatelet therapy for preventing further vascular events after transient ischaemic attack or minor stroke of presumed arterial origin. Cochrane Database Syst Rev 2006;3:CD001342.
    • (2006) Cochrane Database Syst Rev , vol.3
    • Algra, A.1    De Schryver, E.L.2    van Gijn, J.3    Kappelle, L.J.4    Koudstaal, P.J.5
  • 45
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee: A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996;348:1329-1339.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 46
    • 3242770664 scopus 로고    scopus 로고
    • Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, double-blind, placebo-controlled trial
    • Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, Leys D, Matias-Guiu J, Rupprecht HJ: Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet 2004;364:331-337.
    • (2004) Lancet , vol.364 , pp. 331-337
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3    Cimminiello, C.4    Csiba, L.5    Kaste, M.6    Leys, D.7    Matias-Guiu, J.8    Rupprecht, H.J.9
  • 48
    • 0037407217 scopus 로고    scopus 로고
    • Deaths associated with platelet glycoprotein IIb/IIIa inhibitor treatment
    • Brown DL: Deaths associated with platelet glycoprotein IIb/IIIa inhibitor treatment. Heart 2003;89:535-537.
    • (2003) Heart , vol.89 , pp. 535-537
    • Brown, D.L.1
  • 50
    • 0036263813 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 polymorphisms: A comprehensive review of the in vitro and human data
    • Lee CR, Goldstein JA, Pieper JA: Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in vitro and human data. Pharmacogenetics 2002;12:251-263.
    • (2002) Pharmacogenetics , vol.12 , pp. 251-263
    • Lee, C.R.1    Goldstein, J.A.2    Pieper, J.A.3
  • 52
    • 34247141066 scopus 로고    scopus 로고
    • Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives
    • Yin T, Miyata T: Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives. Thromb Res 2007;120:1-10.
    • (2007) Thromb Res , vol.120 , pp. 1-10
    • Yin, T.1    Miyata, T.2
  • 53
    • 42449158953 scopus 로고    scopus 로고
    • Pruissen DM, Rosendaal FR, Gorter J, Garcia AA, Kappelle LJ, Algra A: Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin. J Neurol, Epub ahead of print
    • Pruissen DM, Rosendaal FR, Gorter J, Garcia AA, Kappelle LJ, Algra A: Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin. J Neurol, Epub ahead of print.
  • 54
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high-risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration: Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high-risk patients. BMJ 2002;324:71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 56
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and clopidogrel: Efficacy, safety, and the issue of drug resistance
    • Cattaneo M: Aspirin and clopidogrel: efficacy, safety, and the issue of drug resistance. Arterioscler Thromb Vasc Biol 2004;24:1980-1987.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 57
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S: Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002;105:1650-1655.
    • (2002) Circulation , vol.105 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3    Johnston, M.4    Yi, Q.5    Yusuf, S.6
  • 58
    • 0037256309 scopus 로고    scopus 로고
    • Genetic variation in cyclooxygenase 1: Effects on response to aspirin
    • Halushka MK, Walker LP, Halushka PV: Genetic variation in cyclooxygenase 1: effects on response to aspirin. Clin Pharmacol Ther 2003;73:122-130.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 122-130
    • Halushka, M.K.1    Walker, L.P.2    Halushka, P.V.3
  • 60
    • 1642309585 scopus 로고    scopus 로고
    • Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke
    • Hillarp A, Palmqvist B, Lethagen S, Villoutreix BO, Mattiasson I: Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke. Thromb Res 2003;112:275-283.
    • (2003) Thromb Res , vol.112 , pp. 275-283
    • Hillarp, A.1    Palmqvist, B.2    Lethagen, S.3    Villoutreix, B.O.4    Mattiasson, I.5
  • 61
    • 33646940781 scopus 로고    scopus 로고
    • Aspirin resistance in coronary artery disease is correlated to elevated markers for oxidative stress but not to the expression of cyclooxygenase (COX) 1/2, a novel COX-1 polymorphism or the PlA(1/2) polymorphism
    • Kranzhofer R, Ruef J: Aspirin resistance in coronary artery disease is correlated to elevated markers for oxidative stress but not to the expression of cyclooxygenase (COX) 1/2, a novel COX-1 polymorphism or the PlA(1/2) polymorphism. Platelets 2006;17:163-169.
    • (2006) Platelets , vol.17 , pp. 163-169
    • Kranzhofer, R.1    Ruef, J.2
  • 63
    • 0037422559 scopus 로고    scopus 로고
    • Aspirin alters the cardioprotective effects of the factor XIII Val34Leu polymorphism
    • Undas A, Sydor WJ, Brummel K, Musial J, Mann KG, Szczeklik A: Aspirin alters the cardioprotective effects of the factor XIII Val34Leu polymorphism. Circulation 2003;107:17-20.
    • (2003) Circulation , vol.107 , pp. 17-20
    • Undas, A.1    Sydor, W.J.2    Brummel, K.3    Musial, J.4    Mann, K.G.5    Szczeklik, A.6
  • 64
    • 0025042513 scopus 로고
    • Lack of platelet response to collagen associated with an autoantibody against glycoprotein Ia: A novel cause of acquired qualitative platelet dysfunction
    • Deckmyn H, Chew SL, Vermylen J: Lack of platelet response to collagen associated with an autoantibody against glycoprotein Ia: a novel cause of acquired qualitative platelet dysfunction. Thromb Haemost 1990;64:74-79.
    • (1990) Thromb Haemost , vol.64 , pp. 74-79
    • Deckmyn, H.1    Chew, S.L.2    Vermylen, J.3
  • 65
    • 0023897855 scopus 로고
    • Deficiency of intact thrombospondin and membrane glycoprotein Ia in platelets with defective collagen-induced aggregation and spontaneous loss of disorder
    • Kehrel B, Balleisen L, Kokott R, Mesters R, Stenzinger W, Clemetson KJ, van de Loo J: Deficiency of intact thrombospondin and membrane glycoprotein Ia in platelets with defective collagen-induced aggregation and spontaneous loss of disorder. Blood 1988;71:1074-1078.
    • (1988) Blood , vol.71 , pp. 1074-1078
    • Kehrel, B.1    Balleisen, L.2    Kokott, R.3    Mesters, R.4    Stenzinger, W.5    Clemetson, K.J.6    van de Loo, J.7
  • 67
    • 0035760865 scopus 로고    scopus 로고
    • Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes
    • O'Connor FF, Shields DC, Fitzgerald A, Cannon CP, Braunwald E, Fitzgerald DJ: Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes. Blood 2001;98:3256-3260.
    • (2001) Blood , vol.98 , pp. 3256-3260
    • O'Connor, F.F.1    Shields, D.C.2    Fitzgerald, A.3    Cannon, C.P.4    Braunwald, E.5    Fitzgerald, D.J.6
  • 68
    • 0033982043 scopus 로고    scopus 로고
    • European/Australian Stroke Prevention in Reversible Ischaemia Trial (ESPRIT) group: Design of ESPRIT: an international randomized trial for secondary prevention after non-disabling cerebral ischaemia of arterial origin
    • De Schryver EL; European/Australian Stroke Prevention in Reversible Ischaemia Trial (ESPRIT) group: Design of ESPRIT: an international randomized trial for secondary prevention after non-disabling cerebral ischaemia of arterial origin. Cerebrovasc Dis 2000;10:147-150.
    • (2000) Cerebrovasc Dis , vol.10 , pp. 147-150
    • De Schryver, E.L.1
  • 70
    • 0348046469 scopus 로고    scopus 로고
    • Polymorphisms and Risk of Ischemic Stroke (POLARIS) study: Rationale and design
    • Pruissen DM, Kappelle LJ, Algra A: Polymorphisms and Risk of Ischemic Stroke (POLARIS) study: rationale and design. Eur Neurol 2004;51:30-34.
    • (2004) Eur Neurol , vol.51 , pp. 30-34
    • Pruissen, D.M.1    Kappelle, L.J.2    Algra, A.3
  • 71
    • 33646596912 scopus 로고    scopus 로고
    • Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): Randomised controlled trial
    • Halkes PH, van Gijn J, Kappelle LJ, Koudstaal PJ, Algra A: Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial. Lancet 2006;367:1665-1673.
    • (2006) Lancet , vol.367 , pp. 1665-1673
    • Halkes, P.H.1    van Gijn, J.2    Kappelle, L.J.3    Koudstaal, P.J.4    Algra, A.5
  • 72
    • 33846230041 scopus 로고    scopus 로고
    • Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): A randomised controlled trial
    • The ESPRIT Study Group
    • The ESPRIT Study Group: Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): a randomised controlled trial. Lancet Neurol 2007;6:115-124.
    • (2007) Lancet Neurol , vol.6 , pp. 115-124
  • 73
    • 33745156832 scopus 로고    scopus 로고
    • Classification of cause of death after stroke in clinical research
    • The ESPRIT Study Group
    • The ESPRIT Study Group: Classification of cause of death after stroke in clinical research. Stroke 2006;37:1521-1524.
    • (2006) Stroke , vol.37 , pp. 1521-1524
  • 74
    • 0030069896 scopus 로고    scopus 로고
    • Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • Harrell FE Jr, Lee KL, Mark DB: Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996;15:361-387.
    • (1996) Stat Med , vol.15 , pp. 361-387
    • Harrell Jr, F.E.1    Lee, K.L.2    Mark, D.B.3
  • 76
    • 0023944260 scopus 로고
    • The Dutch TIA trial: Protective effects of low-dose aspirin and atenolol in patients with transient ischemic attacks or nondisabling stroke
    • Dutch TIA Study Group
    • Dutch TIA Study Group: The Dutch TIA trial: protective effects of low-dose aspirin and atenolol in patients with transient ischemic attacks or nondisabling stroke. Stroke 1988;19:512-517.
    • (1988) Stroke , vol.19 , pp. 512-517
  • 77
    • 0028221102 scopus 로고
    • SPIRIT: New life spirit for anticoagulant treatment in the secondary prevention of brain infarcts? A new study - Stroke Prevention in Reversible Ischaemia Trial
    • Algra A: SPIRIT: new life spirit for anticoagulant treatment in the secondary prevention of brain infarcts? A new study - Stroke Prevention in Reversible Ischaemia Trial. Ned Tijdschr Geneeskd 1994;138:1037-1039.
    • (1994) Ned Tijdschr Geneeskd , vol.138 , pp. 1037-1039
    • Algra, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.