Polymorphisms of coagulation factor XIII subunit A and risk of nonfatal hemorrhagic stroke in young white women

Stroke

Volumn 32, Issue 11, 2001, Pages 2580-2585

  Reiner, Alexander P ^a,e   Schwartz, Stephen M ^a,b,c   Frank, Michele B ^a   Longstreth Jr , W T ^a,b   Hindorff, Lucia A ^a   Teramura, Gayle ^a   Rosendaal, Frits R ^d   Gaur, Lakshmi K ^a   Psaty, Bruce M ^a,b   Siscovick, David S ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e NONE   (United States)

Author keywords

Factor XIII; Hemorrhagic stroke; Plasminogen activator inhibitor 1

Indexed keywords

BLOOD CLOTTING FACTOR 13A; PLASMINOGEN ACTIVATOR INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ADULT; ALLELE; ARTICLE; BRAIN HEMORRHAGE; CLINICAL ARTICLE; CONTROLLED STUDY; FATALITY; FEMALE; FIBRINOLYSIS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HEMOSTASIS; HOMOZYGOSITY; HUMAN; MALE; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; RISK FACTOR; STROKE; SUBARACHNOID HEMORRHAGE; TISSUE REPAIR; ADOLESCENT; CASE CONTROL STUDY; CAUCASIAN; CEREBROVASCULAR ACCIDENT; ETHNOLOGY; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; ALLELES; CASE-CONTROL STUDIES; CAUCASOID RACE; CEREBRAL HEMORRHAGE; CEREBROVASCULAR ACCIDENT; FACTOR XIIIA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMAN; LINKAGE DISEQUILIBRIUM; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM (GENETICS); POLYMORPHISM, SINGLE NUCLEOTIDE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035160481     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/hs1101.098150     Document Type: Article

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11. The Leu564 factor XIIIA variant results in significantly lower plasma factor XIII levels than the Pro564 variant
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14. Allele-specific increase in basal transcription of the plasminogen activator inhibitor 1 gene is associated with myocardial infarction
15. The 4G/4G genotype at nucleotide position -675 in the promoter region of the plasminogen activator inhibitor 1 (PAI-1) gene is less frequent in young patients with minor stroke than controls
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