Lipid infusion therapy: Translation to clinical practice

Anesthesia and Analgesia

Volumn 106, Issue 5, 2008, Pages 1340-1342

  Weinberg, Guy L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; AMFEBUTAMONE; BUPIVACAINE; INTRALIPID; LIPID EMULSION; LIPOSYN; LOCAL ANESTHETIC AGENT; MEDIALIPID; MEPIVACAINE; UNCLASSIFIED DRUG; VASOPRESSIN;

CARDIOPULMONARY BYPASS; CARDIOTOXICITY; CLINICAL PRACTICE; CONTINUOUS INFUSION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG OVERDOSE; EDITORIAL; HEART ARREST; HEART ARRHYTHMIA; HUMAN; LOCAL ANESTHESIA; NONHUMAN; PRIORITY JOURNAL; REGIONAL ANESTHESIA; SHOCK; CHEMICALLY INDUCED DISORDER; EMERGENCY TREATMENT; EVIDENCE BASED MEDICINE; HEMODYNAMICS; NERVE BLOCK; NOTE; PATHOPHYSIOLOGY; PRACTICE GUIDELINE; RESUSCITATION;

ANESTHETICS, LOCAL; ARRHYTHMIAS, CARDIAC; EMERGENCY TREATMENT; EVIDENCE-BASED MEDICINE; FAT EMULSIONS, INTRAVENOUS; HEART ARREST; HEMODYNAMICS; HUMANS; NERVE BLOCK; PRACTICE GUIDELINES AS TOPIC; RESUSCITATION;

EID: 42449129712     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e31816a6c09     Document Type: Editorial

References (23)

1. Litz RJ, Roessel T, Heller AR, Stehr SN. Reversal of central nervous system and cardiac toxicity after local anesthetic intoxication by lipid emulsion injection. Anesth Analg 2008;106:1575-7
2. Ludot H, Tharin J-Y, Belooudah M, Mazoit J-X, Malinovsky J-M. Successful resuscitation after ropivacaine and liocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child. Anesth Analg 2008;106:1572-4
3. Mayr VD, Mitterschiffthaler L, Neurauter A, Gritsch C, Wenzel V, Müller T, Luckner G, Linder KH, Strohmenger H-U. A comparison of the combination of epinephrine and vasopressin with lipid emulsion in a porcine model of asphyxial cardiac arrest after intravenous injection of bupivacaine. Anesth Analg 2008;106:1566-71
4. Warren J, Brian T, Georgescu A, Shah S. Intravenous lipid infusion in the successful resuscitation of local anesthetic-induced cardiovascular collapse after supraclavicular brachial plexus block. Anesth Analg 2008;106:1578-80
5. Ruetsch YA, Boni T, Borgeat A. From cocaine to ropivacaine: the history of local anesthetic drugs. Curr Top Med Chem 2001;1:175-82
6. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology 1979;51:285-7
7. Long WB, Rosenblum S, Grady IP. Successful resuscitation of bupivacaine-induced cardiac arrest using cardiopulmonary bypass. Anesth Analg 1989;69:403-6
8. Weinberg G, Ripper R, Feinstein DL, Hoffman W. Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity. Reg Anesth Pain Med 2003;28:198-202
9. Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. Anesthesiology 1998;88:1071-5
10. Weinberg GL, Ripper R, Murphy P, Edelman LB, Hoffman W, Strichartz G, Feinstein DL. Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart. Reg Anesth Pain Med 2006;31:296-303
11. Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB. Successful Use of a 20% Lipid Emulsion to Resuscitate a Patient after a Presumed Bupivacaine-related Cardiac Arrest. Anesthesiology 2006;105:217-8
12. Litz RJ, Popp M, Stehr SN, Koch T. Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion. Anaesthesia 2006;61:800-1
13. Foxall G, McCahon R, Lamb J, Hardman JG, Bedforth NM. Levobupivacaine-induced seizures and cardiovascular collapse treated with Intralipid. Anaesthesia 2007;62:516-8
14. Zimmer C, Piepenbrink K, Riest G, Peters J. [Cardiotoxic and neurotoxic effects after accidental intravascular bupivacaine administration: therapy with lidocaine propofol and lipid emulsion.] Anaesthesist 2007;56:449-53
15. Weinberg GL, Palmer JW, VadeBoncouer TR, Zuechner MB, Edelman G, Hoppel CL. Bupivacaine inhibits acylcarnitine exchange in cardiac mitochondria. Anesthesiology 2000;92:523-8
16. Cho HS, Lee JJ, Chung IS, Shin BS, Kim JA, Lee KH. Insulin reverses bupivacaine-induced cardiac depression in dogs. Anesth Analg 2000;91:1096-102
17. Weinberg G, VadeBoncouer T. Improved energetics may explain the favorable effect of insulin infusion on bupivacaine cardiotoxicity. Anesth Analg 2001;92:1075-6
18. Stehr SN, Pexa A, Hannack S, Heintz A, Heller AR, Deussen A, Koch T, Hübler M. The effects of lipid infusion on myocardial function and bioenergetics in l-bupivacaine toxicity in the isolated rat heart. Anesth Analg 2007;104:186-92
19. Di Gregorio G, Ripper R, Kelly K, Weinberg G. Vasopressin is associated with adverse outcomes in resuscitation from bupivacaine-induced asystole. Abstract 1076, IARS 82nd Congress, San Francisco, 2008
20. Weinberg G. Lipid infusion resuscitation for local anesthetic toxicity: proof of clinical efficacy. Anesthesiology 2006;105:7-8
21. Corcoran W, Butterworth J, Weller RS, Beck JC, Gerancher JC, Houle TT, Groban L. Local anesthetic-induced cardiac toxicity: a survey of contemporary practice strategies among academic anesthesiology departments. Anesth Analg 2006;103:1322-6
22. Mulroy MF. Systemic toxicity and cardiotoxicity from local anesthetics: incidence and preventive measures. Reg Anesth Pain Med 2002;27:556-61
23. Sirianni AJ, Osterhoudt KC, Calello DP, Muller AA, Waterhouse MR, Goodkin MB, Weinberg GL, Henretig FM. Use of a lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of bupropion and lamotrigine. Ann Emerg Med 2007; E-pub ahead of print