Improved energetics may explain the favorable effect of insulin infusion on bupivacaine cardiotoxicity [8]

Anesthesia and Analgesia

Volumn 92, Issue 4, 2001, Pages 1075-1076

  Weinberg, G ^a   VadeBoncouer, T ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; BUPIVACAINE; GLUCOSE; INSULIN; POTASSIUM;

CARDIOTOXICITY; DOG; DRUG MECHANISM; ENZYME ACTIVATION; HEART FUNCTION; HEART OUTPUT; INSULIN INFUSION; LETTER; MITOCHONDRIAL RESPIRATION; NEUROTOXICITY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; POTASSIUM CURRENT; PRIORITY JOURNAL;

EID: 0035080047     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200104000-00061     Document Type: Letter

References (6)

1. Insulin reverses bupivacaine-induced cardiac depression in dogs
2. Uncoupling effects of local anesthetics on rat liver mitochondria
3. Mechanism of local anesthetic effect on mitochondrial ATP synthase as deduced from photolabelling and inhibition studies with phenothiazine derivatives
4. Comparison of the effects of bupivacaine and ropivacaine on heart cell mitochondrial bioenergetics
5. In vitro study on mechanisms of bupivacaine-induced depression of myocardial contractility
6. Bupivacaine inhibits acylcarnitine exchange in cardiac mitochondria