Cardiotoxic and neurotoxic effects after accidental intravascular bupivacaine administration. Therapy with lidocaine propofol and lipid emulsion;Kardio- und neurotoxische nebenwirkungen nach akzidenteller intravasaler bupivacainapplikation. Therapie mit lidocain, propofol und lipidemulsion
Auroy Y, Narchi P, Messiah A et al. (1997) Serious complications related to regional anesthesia: results of a prospective survey in France. Anesthesiology 87: 479-486
Clarkson CW, Hondeghem LM (1985) Mechanism for bupivacaine depression of cardiac conduction: fast block of sodium channels during the action potential with slow recovery from block during diastole. Anesthesiology 62: 396-405
Heavner J, Arthur J, Zou J et al. (1993) Comparison of propofol with thiopentone for treatment of bupivacaine-induced seizures in rats. Br J Anaesth 71: 715-719
Knudsen K, Beckmann Suurküla M, Blomberg S et al. (1997) Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers. Br J Anaesth 78: 507-514
Litz RJ, Popp M, Stehr SN, Koch T (2006) Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion. Anaesthesia 61: 800-801
Ohmura S, Ohta T, Yamamoto K, Kobayashi T (1999) A comparison of the effects of propofol and sevoflurane on the systemic toxicity of intravenous bupivacaine in rats. Anesth Analg 88: 155-159
Rosenblatt MA, Abel M, Fischer GW et al. (2006) Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine related cardiac arrest. Anesthesiology 105: 217-218
Veering BT, Burm AG, Vletter AA et al. (1991) The effect of age on systemic absorption and systemic disposition of bupivacaine after subarachnoid administration. Anesthesiology 74: 250-257
Weinberg GL, VadeBoncouer T, Ramaraju GA et al. (1998) Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. Anesthesiology 88: 1071-1075
Weinberg GL, Ripper R, Murphy P et al. (2006) Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart. Reg Anesth Pain Med 31: 296-303