The kinetics and redox state of nitric oxide determine the biological consequences in lung adenocarcinoma

Tumor Biology

Volumn 28, Issue 6, 2007, Pages 301-311

  Bentz, Brandon G ^a   Hammer, Neal D ^c   Milash, Brett ^b   Klein, Slobodanka ^e   Burnett, David M ^a   Radosevich, James A ^c   Haines III, G Kenneth ^d  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Instituto de Oncologia Angel H Roffo   (Argentina)

Author keywords

Apoptosis; Mutation; Nitric oxide; Tumor progression

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE; COMPLEMENTARY DNA; NITRIC OXIDE; REACTIVE NITROGEN SPECIES;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA MICROARRAY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; KINETICS; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MEASUREMENT; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

EID: 42449123546     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000115526     Document Type: Article

References (29)

1. Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 2000;100:57-70.
2. Bentz BG, Barnes MN, Haines GK, Lurain JR, Hanson DG, Radosevich JA: Cytoplasmic localization of endothelial constitutive nitric oxide synthase in endometrial carcinomas. Tumor Biol 1997;18:290-300.
3. Bentz BG, Haines GK 3rd, Hanson DG, Radosevich JA: Endothelial constitutive nitric oxide synthase (ecNOS) localization in normal and neoplastic salivary tissue. Head Neck 1998;20:304-309.
4. Bentz BG, Haines GK 3rd, Lingen MW, Pelzer HJ, Hanson DG, Radosevich JA: Nitric oxide synthase type 3 is increased in squamous hyperplasia, dysplasia, and squamous cell carcinoma of the head and neck. Ann Otol Rhinol Laryngol 1999;108:781-787.
5. Bentz BG, Haines GK 3rd, Radosevich JA: Increased protein nitrosylation in head and neck squamous cell carcinogenesis. Head Neck 2000;22:64-70.
6. Bentz BG, Haines GK 3rd, Radosevich JA: Glutathione S-transferase pi in squamous cell carcinoma of the head and neck. Laryngoscope 2000;110:1642-1647.
7. Bentz BG, Hammer ND, Radosevich JA, Haines GK 3rd: Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line. J Carcinog 2004;3:16.
8. Diament MJ, Garcia C, Stillitani I, Saavedra VM, Manzur T, Vauthay L, Klein S: Spontaneous murine lung adenocarcinoma (P07): a new experimental model to study paraneoplastic syndromes of lung cancer. Int J Mol Med 1998;2:45-50.
9. Parma M, Diament M, Garcia C, Piccinni E, Mondelo N, Klein S: Mechanisms of paraneoplastic syndromes in mice bearing a spontaneous lung adenocarcinoma. Tumor Biol 1999;20:304-311.
10. Wink DA, Vodovotz Y, Laval J, Laval F, Dewhirst MW, Mitchell JB: The multifaceted roles of nitric oxide in cancer. Carcinogenesis 1998;19:711-721.
11. Liu RH, Hotchkiss JH: Potential genotoxicity of chronically elevated nitric oxide: a review. Mutat Res 1995;339:73-89.
12. Bentz BG, Chandra R, Haines GK 3rd, Robinson AM, Shah P, Radosevich JA: Nitric oxide and apoptosis during human head and neck squamous cell carcinoma development. Am J Otolaryngol 2002;23:4-11.
13. He J, Xiao Y, Casiano CA, Zhang L: Role of mitochondrial cytochrome c in cocaine-induced apoptosis in coronary artery endothelial cells. J Pharmacol Exp Ther 2000;295:896-903.
14. Natarajan N, Shambaugh GE 3rd, Elseth KM, Haines GK, Radosevich JA: Adaptation of the diphenylamine (DPA) assay to a 96-well plate tissue culture format and comparison with the MTT assay. Biotechniques 1994;17:166-171.
15. Ridnour LA, Thomas DD, Donzelli S, Espey MG, Roberts DD, Wink DA, Isenberg JS: The biphasic nature of nitric oxide responses in tumor biology. Antioxid Redox Signal 2006;8:1329-1337.
16. Stepnik M: Roles of nitric oxide in carcinogenesis. Protumorigenic effects. Int J Occup Med Environ Health 2002;15:219-227.
17. Li CQ, Trudel LJ, Wogan GN: Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53. Proc Natl Acad Sci USA 2002;99:10364-10369.
18. Tamir S, deRojas-Walker T, Wishnok JS, Tannenbaum SR: DNA damage and genotoxicity by nitric oxide. Methods Enzymol 1996;269:230-243.
19. Ohshima H, Tatemichi M, Sawa T: Chemical basis of inflammation-induced carcinogenesis. Arch Biochem Biophys 2003;417:3-11.
20. Kawanishi S, Hiraku Y, Pinlaor S, Ma N: Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem 2006;387:365-372.
21. Niles JC, Wishnok JS, Tannenbaum SR: Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation. Nitric Oxide 2006;14:109-121.
22. Billiar TR: The delicate balance of nitric oxide and superoxide in liver pathology. Gastroenterology 1995;108:603-605.
23. Wink DA, Cook JA, Kim SY, Vodovotz Y, Pacelli R, Krishna MC, Russo A, Mitchell JB, Jourd'heuil D, Miles AM, Grisham MB: Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates. Chemical aspects involved in the balance between oxidative and nitrosative stress. J Biol Chem 1997;272:11147-11151.
24. Ohshima H, Bartsch H: Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat Res 1994;305:253-264.
25. Ohshima H, Bartsch H: Quantitative estimation of endogenous N-nitrosation in humans by monitoring N-nitrosoproline in urine. Methods Enzymol 1999;301:40-49.
26. Li J, Billiar TR, Talanian RV, Kim YM: Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem Biophys Res Commun 1997;240:419-424.
27. Kim YM, Talanian RV, Billiar TR: Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J Biol Chem 1997;272:31138-31148.
28. Ouyang N, Williams JL, Tsioulias GJ, Gao J, Iatropoulos MJ, Kopelovich L, Kashfi K, Rigas B: Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model. Cancer Res 2006;66:4503-4511.
29. De Santo C, Serafini P, Marigo I, Dolcetti L, Bolla M, Del Soldato P, Melani C, Guiducci C, Colombo MP, Iezzi M, Musiani P, Zanovello P, Bronte V: Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination. Proc Natl Acad Sci USA 2005;102:4185-4190.