-
1
-
-
4644289587
-
Multitargeted drugs: The end of the "one-target-one-disease" philosophy?
-
10.1016/S1359-6446(04)03213-1 15381132
-
Wermuth CG: MulTitargeted drugs: the end of the "one-target-one-disease" philosophy?. Drug Discov Today 2004, 9:826-827. 10.1016/S1359-6446(04)03213-1 15381132
-
(2004)
Drug Discov Today
, vol.9
, pp. 826-827
-
-
Wermuth, C.G.1
-
2
-
-
23044464476
-
Ethnopharmacology and drug discovery
-
10.1016/j.jep.2005.06.006 16023811
-
Patwardhan B: Ethnopharmacology and drug discovery. J Ethnopharmacol 2005, 100:50-52. 10.1016/j.jep.2005.06.006 16023811
-
(2005)
J Ethnopharmacol
, vol.100
, pp. 50-52
-
-
Patwardhan, B.1
-
3
-
-
28644451833
-
Ayurveda and traditional Chinese medicine: A comparative overview
-
1297513 16322803 10.1093/ecam/neh140
-
Patwardhan B Warude D Pushpangadan P Bhatt N: Ayurveda and traditional Chinese medicine: A comparative overview. Evid Based Complement Alternat Med 2005, 2:465-473. 1297513 16322803 10.1093/ecam/neh140
-
(2005)
Evid Based Complement Alternat Med
, vol.2
, pp. 465-473
-
-
Patwardhan, B.1
Warude, D.2
Pushpangadan, P.3
Bhatt, N.4
-
4
-
-
33947148594
-
A standarized root extract of Whithania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice
-
10.1016/j.lfs.2007.01.029 17336338
-
Malik F Singh J Khajuria A Suri KA Satti NK Singh S Kaul MK Kumar A Bhatia A Qazi GN: A standarized root extract of Whithania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice. Life Sci 2007, 80:1525-1538. 10.1016/j.lfs.2007.01.029 17336338
-
(2007)
Life Sci
, vol.80
, pp. 1525-1538
-
-
Malik, F.1
Singh, J.2
Khajuria, A.3
Suri, K.A.4
Satti, N.K.5
Singh, S.6
Kaul, M.K.7
Kumar, A.8
Bhatia, A.9
Qazi, G.N.10
-
5
-
-
3342924484
-
Future Medicare system
-
15266930
-
Hegde BM: Future Medicare system. J Assoc Physicians India 2003, 51:606-608. 15266930
-
(2003)
J Assoc Physicians India
, vol.51
, pp. 606-608
-
-
Hegde, B.M.1
-
6
-
-
0033845752
-
Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): A review
-
10956379
-
Mishra LC Singh BB Dagenais S: Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): A review. Altern Med Rev 2000, 5:334-346. 10956379
-
(2000)
Altern Med Rev
, vol.5
, pp. 334-346
-
-
Mishra, L.C.1
Singh, B.B.2
Dagenais, S.3
-
7
-
-
33845959087
-
Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology
-
17176166
-
Winters M: Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology. Altern Med Rev 2006, 11:269-277. 17176166
-
(2006)
Altern Med Rev
, vol.11
, pp. 269-277
-
-
Winters, M.1
-
9
-
-
34848858255
-
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine
-
10.1007/s10495-007-0129-x 17874299
-
Malik F Kumar A Bhushan S Khan S Bhatia A Suri KA Qazi GN Singh J: Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine. Apoptosis 2007, 12:2115-2133. 10.1007/s10495-007-0129-x 17874299
-
(2007)
Apoptosis
, vol.12
, pp. 2115-2133
-
-
Malik, F.1
Kumar, A.2
Bhushan, S.3
Khan, S.4
Bhatia, A.5
Suri, K.A.6
Qazi, G.N.7
Singh, J.8
-
10
-
-
0026576168
-
In vivo growth inhibitory effect of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma 180
-
1512021
-
Devi PU Sharada AC Solomon FE Kamath MS: In vivo growth inhibitory effect of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma 180. Indian J Exp Biol 1992, 30:169-172. 1512021
-
(1992)
Indian J Exp Biol
, vol.30
, pp. 169-172
-
-
Devi, P.U.1
Sharada, A.C.2
Solomon, F.E.3
Kamath, M.S.4
-
11
-
-
0027323414
-
Antitumor and radiosensitizing effects of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma-180
-
8225418
-
Devi PU Sharada AC Solomon FE: Antitumor and radiosensitizing effects of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma-180. Indian J Exp Biol 1993, 31:607-611. 8225418
-
(1993)
Indian J Exp Biol
, vol.31
, pp. 607-611
-
-
Devi, P.U.1
Sharada, A.C.2
Solomon, F.E.3
-
12
-
-
0015808467
-
Effect of withaferin A on cells in tissue culture
-
10.1007/BF00305128 4271956
-
Shohat B: Effect of withaferin A on cells in tissue culture. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol 1973, 80:97-102. 10.1007/ BF00305128 4271956
-
(1973)
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol
, vol.80
, pp. 97-102
-
-
Shohat, B.1
-
14
-
-
0014946897
-
Effect of withaferin A on Ehrlich ascites tumor cells-cytological observations
-
10.1002/ijc.2910050212 5449164
-
Shohat B Gitter S Lavie D: Effect of withaferin A on Ehrlich ascites tumor cells-cytological observations. Int J Cancer 1970, 5:244-252. 10.1002/ijc.2910050212 5449164
-
(1970)
Int J Cancer
, vol.5
, pp. 244-252
-
-
Shohat, B.1
Gitter, S.2
Lavie, D.3
-
15
-
-
0015227605
-
Effect of withaferin A on ehrlich ascites tumor cells. II. Target tumor cell destruction in vivo by immune activation
-
5002873
-
Shohat B Joshua H: Effect of withaferin A on ehrlich ascites tumor cells. II. Target tumor cell destruction in vivo by immune activation. Int J Cancer 1971, 8:487-496. 5002873
-
(1971)
Int J Cancer
, vol.8
, pp. 487-496
-
-
Shohat, B.1
Joshua, H.2
-
16
-
-
34247536630
-
Selective killing of cancer cells by leaf extract of Ashwagandha: Identification of a tumor-inhibitory factor and the first molecular insights to its effect
-
10.1158/1078-0432.CCR-06-0948
-
Widodo N Kaur K Shrestha BG Takagi Y Ishii Wadhwa R Kaul SC Selective killing of cancer cells by leaf extract of Ashwagandha: Identification of a tumor-inhibitory factor and the first molecular insights to its effect Clin Cancer Res 2007 13 2298 2306 10.1158/1078-0432.CCR-06-0948 17404115
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2298-2306
-
-
Widodo, N.1
Kaur, K.2
Shrestha, B.G.3
Takagi, Y.4
Ishii Wadhwa, R.5
Kaul, S.C.6
-
17
-
-
42449099302
-
Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses
-
Widodo N Takagi Y Shrestha BG Ishii T Kaul SC Wadhwa R: Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses. Cancer Lett 2008 2008, Jan 9 18191020
-
(2008)
Cancer Lett
-
-
Widodo, N.1
Takagi, Y.2
Shrestha, B.G.3
Ishii, T.4
Kaul, S.C.5
Wadhwa, R.6
-
18
-
-
33947192027
-
Withanolide induces apoptosis in HL-60 leukemia cells via mitochondria mediated cytochrome c release and caspase activation
-
10.1016/j.cbi.2007.01.004 17328876
-
Senthil V Ramadevi S Venkatakrishnan V Giridharan P Lakshmi BS Vishwakarma RA Balakrishnan A: Withanolide induces apoptosis in HL-60 leukemia cells via mitochondria mediated cytochrome c release and caspase activation. Chem Biol Interact 2007, 167:19-30. 10.1016/ j.cbi.2007.01.004 17328876
-
(2007)
Chem Biol Interact
, vol.167
, pp. 19-30
-
-
Senthil, V.1
Ramadevi, S.2
Venkatakrishnan, V.3
Giridharan, P.4
Lakshmi, B.S.5
Vishwakarma, R.A.6
Balakrishnan, A.7
-
19
-
-
0035682347
-
Downregulation of p34cdc2 expression with aqueous fraction from Withania somnifera for a possible molecular mechanism of anti-tumor and other pharmacological effects
-
10.1078/S0944-7113(04)70072-0 11824528
-
Singh DD Dey CS Bhutani KK: Downregulation of p34cdc2 expression with aqueous fraction from Withania somnifera for a possible molecular mechanism of anti-tumor and other pharmacological effects. Phytomedicine 2001, 8:492-494. 10.1078/S0944-7113(04)70072-0 11824528
-
(2001)
Phytomedicine
, vol.8
, pp. 492-494
-
-
Singh, D.D.1
Dey, C.S.2
Bhutani, K.K.3
-
20
-
-
33846454701
-
The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry"
-
10.1124/mol.106.030015 17093135
-
Yang H Shi G Dou QP: The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry". Mol Pharmacol 2007, 71:426-437. 10.1124/ mol.106.030015 17093135
-
(2007)
Mol Pharmacol
, vol.71
, pp. 426-437
-
-
Yang, H.1
Shi, G.2
Dou, Q.P.3
-
21
-
-
33846436451
-
Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells
-
10.1158/0008-5472.CAN-06-2430 17185378
-
Srinivasan S Ranga RS Burikhanov R Han SS Chendil D: Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells. Cancer Res 2007, 67:246-253. 10.1158/0008-5472.CAN-06-2430 17185378
-
(2007)
Cancer Res
, vol.67
, pp. 246-253
-
-
Srinivasan, S.1
Ranga, R.S.2
Burikhanov, R.3
Han, S.S.4
Chendil, D.5
-
22
-
-
77953467771
-
Sensitization of human cancer cells to anti-cancer drugs by leaf extract of Ashwagandha (LASH)
-
Kaur K Widodo N Nagpal A Kaul SC Wadhwa R: Sensitization of human cancer cells to anti-cancer drugs by leaf extract of Ashwagandha (LASH). Tiss Cult Res Commun 2007, 26:171-183.
-
(2007)
Tiss Cult Res Commun
, vol.26
, pp. 171-183
-
-
Kaur, K.1
Widodo, N.2
Nagpal, A.3
Kaul, S.C.4
Wadhwa, R.5
-
23
-
-
33947530134
-
Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity
-
10.1074/jbc.M606728200 17150968
-
Kaileh M Vanden Berghe W Heyerick A Horion J Piette J Libert C De Keukeleire D Essawi T Haegeman G: Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. J Biol Chem 2007, 282:4253-4264. 10.1074/ jbc.M606728200 17150968
-
(2007)
J Biol Chem
, vol.282
, pp. 4253-4264
-
-
Kaileh, M.1
Vanden Berghe, W.2
Heyerick, A.3
Horion, J.4
Piette, J.5
Libert, C.6
De Keukeleire, D.7
Essawi, T.8
Haegeman, G.9
-
24
-
-
33746048055
-
Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression
-
10.1158/1535-7163.MCT-06-0096 16818501
-
Ichikawa H Takada Y Shishodia S Jayaprakasam B Nair MG Aggarwal BB: Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression. Cancer Ther 2006, 5(6):1434-1445. 10.1158/1535-7163.MCT-06-0096 16818501
-
(2006)
Cancer Ther
, vol.5
, Issue.6
, pp. 1434-1445
-
-
Ichikawa, H.1
Takada, Y.2
Shishodia, S.3
Jayaprakasam, B.4
Nair, M.G.5
Aggarwal, B.B.6
-
25
-
-
33749317019
-
The application of DNA micro-arrays (gene arrays) to the study of herbal medicines
-
10.1016/j.jep.2006.08.013 16979861
-
Hudson J Altamirano M: The application of DNA micro-arrays (gene arrays) to the study of herbal medicines. J Ethnopharmacol 2006, 108:2-15. 10.1016/j.jep.2006.08.013 16979861
-
(2006)
J Ethnopharmacol
, vol.108
, pp. 2-15
-
-
Hudson, J.1
Altamirano, M.2
-
26
-
-
0041843934
-
Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines
-
10.1038/sj.bjc.6600983 12838319
-
Fustier P Le Corre L Chalabi N Vissac-Sabatier C Communal Y Bignon YJ Bernard-Gallon DJ: Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines. Br J Cancer 2003, 89:168-172. 10.1038/ sj.bjc.6600983 12838319
-
(2003)
Br J Cancer
, vol.89
, pp. 168-172
-
-
Fustier, P.1
Le Corre, L.2
Chalabi, N.3
Vissac-Sabatier, C.4
Communal, Y.5
Bignon, Y.J.6
Bernard-Gallon, D.J.7
-
27
-
-
1842786763
-
Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in mcf-7 cells
-
10.1007/BF02254447 15067226
-
Yang NS Shyur LF Chen CH Wang SY Tzeng CM; Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in mcf-7 cells. J Biomed Sci 2004, 11:418-422. 10.1007/BF02254447 15067226
-
(2004)
J Biomed Sci
, vol.11
, pp. 418-422
-
-
Yang, N.S.1
Shyur, L.F.2
Chen, C.H.3
Wang, S.Y.4
Tzeng, C.M.5
-
28
-
-
1242338646
-
St John's wort and imipramine-induced gene expression profiles identify cellular functions relevant to antidepressant action and novel pharmacogenetic candidates for the phenotype of antidepressant treatment response
-
10.1038/sj.mp.4001470 14743185
-
Wong ML O'Kirwan F Hannestad JP Irizarry KJ Elashoff D Licinio J: St John's wort and imipramine-induced gene expression profiles identify cellular functions relevant to antidepressant action and novel pharmacogenetic candidates for the phenotype of antidepressant treatment response. Mol Psychiatry 2004, 9:237-251. 10.1038/sj.mp.4001470 14743185
-
(2004)
Mol Psychiatry
, vol.9
, pp. 237-251
-
-
Wong, M.L.1
O'Kirwan, F.2
Hannestad, J.P.3
Irizarry, K.J.4
Elashoff, D.5
Licinio, J.6
-
29
-
-
34548407017
-
Discovering functions and revealing mechanisms at molecular level from biological networks
-
10.1002/pmic.200700095 17703505
-
Zhang S Jin G Zhang XS Chen L: Discovering functions and revealing mechanisms at molecular level from biological networks. Proteomics 2007, 7:2856-2869. 10.1002/pmic.200700095 17703505
-
(2007)
Proteomics
, vol.7
, pp. 2856-2869
-
-
Zhang, S.1
Jin, G.2
Zhang, X.S.3
Chen, L.4
-
30
-
-
33646053123
-
Rediscovery of natural products using genomic tools
-
10.1016/j.bmcl.2006.03.022 16580203
-
Kawamura A Brekman A Grigoryev Y Hasson TH Takaoka A Wolfe S Soll CE; Rediscovery of natural products using genomic tools. Bioorg Med Chem Lett 2006, 16:2846-2849. 10.1016/j.bmcl.2006.03.022 16580203
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 2846-2849
-
-
Kawamura, A.1
Brekman, A.2
Grigoryev, Y.3
Hasson, T.H.4
Takaoka, A.5
Wolfe, S.6
Soll, C.E.7
|