Activin-A in myometrium: Characterization of the actions on myometrial cells

Endocrinology

Volumn 149, Issue 5, 2008, Pages 2506-2516

  Ciarmela, Pasquapina ^a,c   Wiater, Ezra ^a   Vale, Wylie ^a,b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR; CONNEXIN 43; CYCLOOXYGENASE 2; FOLLISTATIN; MESSENGER RNA; OXYTOCIN; OXYTOCIN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN SUBUNIT; SMAD2 PROTEIN; SMAD3 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; THROMBOXANE A2; TRANSCRIPTION FACTOR HOXA10;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GROWTH INHIBITION; MYOMETRIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT;

ACTIVINS; ANIMALS; CALCIUM; CELL PROLIFERATION; CELL SIZE; CELLS, CULTURED; CONNEXIN 43; CYCLOOXYGENASE 2; FEMALE; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; MYOMETRIUM; OXYTOCIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROGESTERONE; SIGNAL TRANSDUCTION; UTERINE CONTRACTION;

EID: 42449090272     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0692     Document Type: Article

References (57)

1. Vale W, Wiater E, Gray P, Harrison C, Bilezikjian L, Choe S 2004 Activins and inhibins and their signaling. Ann NY Acad Sci 1038:142-147
2. Leung PH, Salamonsen LA, Findlay JK 1998 Immunolocalization of inhibin and activin subunits in human endometrium across the menstrual cycle. Hum Reprod 13:3469-3477
3. Di Simone N, Schneyer AL, Caliandro D, Castellani R, Caruso A 2002 Regulation of endometrial adenocarcinoma cell proliferation by Activin-A and its modulation by 17β-estradiol. Mol Cell Endocrinol 192:187-195
4. Jones RL, Salamonsen LA, Findlay JK 2002 Activin A promotes human endometrial stromal cell decidualization in vitro. J Clin Endocrinol Metab 87:4001-4004
5. Jones RL, Salamonsen LA, Critchley HO, Rogers PA, Affandi B, Findlay JK 2000 Inhibin and activin subunits are differentially expressed in endometrial cells and leukocytes during the menstrual cycle, in early pregnancy and in women using progestin-only contraception. Mol Hum Reprod 6:1107-1117
6. Meunier H, Rivier C, Evans RM, Vale W 1988 Gonadal and extragonadal expression of inhibin α, β A, and β B subunits in various tissues predicts diverse functions. Proc Natl Acad Sci USA 85:247-251
7. Petraglia F, Anceschi MM, Calza L, Garuti GC, Fusaro P, Giardino L, Gennazzani AR, Vale W 1993 Inhibin and activin in human fetal membranes: evidence for a local effect on prostaglandin release. J Clin Endocrinol Metab 77:542-548
8. Petraglia F, Gallinelli A, De Vita D, Lewis K, Mathews L, Vale W 1994 Activin at parturition: changes of maternal serum levels and evidence for binding sites in placenta and fetal membranes. Obstet Gynecol 84:278-282
9. Caniggia I, Lye SJ, Cross JC 1997 Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology 138:3976-3986
10. He ZY, Liu HC, Mele CA, Barmat L, Veeck LL, Davis O, Rosenwaks Z 1999 Expression of inhibin/activin subunits and their receptors and binding proteins in human preimplantation embryos. J Assist Reprod Genet 16:73-80
11. Schneider-Kolsky M, Manuelpillai U, Gargett C, Wallace EM 2001 Activin βA-subunit and activin receptors in human myometrium at term and during labour. BJOG 108:869-874
12. Hayashi K, Carpenter KD, Gray CA, Spencer TE 2003 The activin-follistatin system in the neonatal ovine uterus. Biol Reprod 69:843-850
13. Draper LB, Chong H, Wang E, Woodruff TK 1997 The uterine myometrium is a target for increased levels of activin A during pregnancy. Endocrinology 138:3042-3046
14. Johansson B 1984 Different types of smooth muscle hypertrophy. Hypertension 6(6 Pt 2):III64-III68
15. Petraglia F, De Vita D, Gallinelli A, Aguzzoli L, Gennazzani AR, Romero R, Woodruff TK 1995 Abnormal concentration of maternal serum activin-A in gestational diseases. J Clin Endocrinol Metab 80:558-561
16. Woodruff TK, Sluss P, Wang E, Janssen I, Mersol-Barg MS 1997 Activin A and follistatin are dynamically regulated during human pregnancy. J Endocrinol 152:167-174
17. Gallinelli A, Gallo R, Genazzani AD, Matteo ML, Caruso A, Woodruff TK, Petraglia F 1996 Episodic secretion of activin A in pregnant women. Eur J Endocrinol 135:340-344
18. Petraglia F, Di Blasio AM, Florio P, Gallo R, Gennazzani AR, Woodruff TK, Vale W 1997 High levels of fetal membrane activin β A and activin receptor IIB mRNAs and augmented concentration of amniotic fluid activin A in women in term or preterm labor. J Endocrinol 154:95-101
19. Farina A, Lambert-Messerlian GM, Canick JA, Banzola I, Carletti A, Concu M, Tempesta A, Gabrielli S, Morano D, Rizzo N 2006 Total activin A in maternal blood as a marker of preterm delivery in low-risk asymptomatic patients. Prenat Diagn 26:277-281
20. Schneider-Kolsky M, D'Antona D, Evans LW, Taylor N, O'Connor A, Groome NP, de Kretser D, Wallace EM 2000 Maternal serum total activin A and follistatin in pregnancy and parturition. BJOG 107:995-1000
21. Plevyak MP, Lambert-Messerlian GM, Farina A, Groome NP, Canick JA, Silver HM 2003 Concentrations of serum total activin A and inhibin A in preterm and term labor patients: a cross-sectional study. J Soc Gynecol Investig 10:231-236
22. Tang XM, Dou Q, Zhao Y, McLean F, Davis J, Chegini N 1997 The expression of transforming growth factor-β s and TGF-β receptor mRNA and protein and the effect of TGF-β s on human myometrial smooth muscle cells in vitro. Mol Hum Reprod 3:233-240
23. Monga M, Ku CY, Dodge K, Sanborn BM 1996 Oxytocin-stimulated responses in a pregnant human immortalized myometrial cell line. Biol Reprod 55:427-432
24. Condon J, Yin S, Mayhew B, Word RA, Wright WE, Shay JW, Rainey WE 2002 Telomerase immortalization of human myometrial cells. Biol Reprod 67:506-514
25. Mesiano S, Chan EC, Fitter JT, Kwek K, Yeo G, Smith R 2002 Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium. J Clin Endocrinol Metab 87:2924-2930
26. Deglise S, Martin D, Probst H, Saucy F, Hayoz D, Waeber G, Nicod P, Ris HB, Corpataux JM, Haefliger JA 2005 Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia. J Vasc Surg 41:1043-1052
27. Lee MJ, Ma Y, LaChapelle L, Kadner SS, Guller S 2004 Glucocorticoid enhances transforming growth factor-β effects on extracellular matrix protein expression in human placental mesenchymal cells. Biol Reprod 70:1246-1252
28. Burroughs KD, Fuchs-Young R, Davis B, Walker CL 2000 Altered hormonal responsiveness of proliferation and apoptosis during myometrial maturation and the development of uterine leiomyomas in the rat. Biol Reprod 63:1322-1330
29. Shynlova O, Oldenhof A, Dorogin A, Xu Q, Mu J, Nashman M, Lye SJ 2006 Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midgestation. Biol Reprod 74:839-849
30. Shikone T, Matzuk MM, Perlas E, Finegold MJ, Lewis KA, Vale W, Bradley A, Hsueh A 1994 Characterization of gonadal sex cord-stromal tumor cell lines from inhibin-α and p53-deficient mice: the role of activin as an autocrine growth factor. Mol Endocrinol 8:983-995
31. Billestrup N, Gonzalez-Manchon C, Potter E, Vale W 1990 Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro. Mol Endocrinol 4:356-362
32. Phaneuf S, Asboth G, Carrasco MP, Europe-Finner GN, Saji F, Kimura T, Harris A, Lopez Bernal A 1997 The desensitization of oxytocin receptors in human myometrial cells is accompanied by down-regulation of oxytocin receptor messenger RNA. J Endocrinol 154:7-18
33. Shynlova O, Mitchell JA, Tsampalieros A, Langille BL, Lye SJ 2004 Progesterone and gravidity differentially regulate expression of extracellular matrix components in the pregnant rat myometrium. Biol Reprod 70:986-992
34. Hertelendy F, Zakar T 2004 Regulation of myometrial smooth muscle functions. Curr Pharm Des 10:2499-2517
35. Rossi MJ, Chegini N, Masterson BJ 1992 Presence of epidermal growth factor, platelet-derived growth factor, and their receptors in human myometrial tissue and smooth muscle cells: their action in smooth muscle cells in vitro. Endocrinology 130:1716-1727
36. Tang XM, Rossi MJ, Masterson BJ, Chegini N 1994 Insulin-like growth factor I (IGF-I), IGF-I receptors, and IGF binding proteins 1-4 in human uterine tissue: tissue localization and IGF-I action in endometrial stromal and myometrial smooth muscle cells in vitro. Biol Reprod 50:1113-1125
37. Barhoumi R, Awooda I, Mouneimne Y, Safe S, Burghardt RC 2006 Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells. Toxicol Lett 165:133-141
38. Burghardt RC, Barhoumi R, Sanborn BM, Andersen J 1999 Oxytocin-induced Ca2+ responses in human myometrial cells. Biol Reprod 60:777-782
39. Burghardt RC, Barhoumi R, Stickney M, Monga M, Ku CY, Sanborn BM 1996 Correlation between connexin43 expression, cell-cell communication, and oxytocin-induced Ca2+ responses in an immortalized human myometrial cell line. Biol Reprod 55:433-438
40. Dodge KL, Carr DW, Sanborn BM 1999 Protein kinase A anchoring to the myometrial plasma membrane is required for cyclic adenosine 3′,5′-monophosphate regulation of phosphatidylinositide turnover. Endocrinology 140:5165-5170
41. Dodge KL, Sanborn BM 1998 Evidence for inhibition by protein kinase A of receptor/G α(q) /phospholipase C (PLC) coupling by a mechanism not involving PLCβ2. Endocrinology 139:2265-2271
42. Madsen G, Zakar T, Ku CY, Sanborn BM, Smith R, Mesiano S 2004 Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawal. J Clin Endocrinol Metab 89:1010-1013
43. Massrieh W, Derjuga A, Doualla-Bell F, Ku CY, Sanborn BM, Blank V 2006 Regulation of the MAFF transcription factor by proinflammatory cytokines in myometrial cells. Biol Reprod 74:699-705
44. Merlino AA, Welsh TN, Tan H, Yi LJ, Cannon V, Mercer BM, Mesiano S 2007 Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased expression of progesterone receptor-A. J Clin Endocrinol Metab 92:1927-1933
45. Monga M, Campbell DF, Sanborn BM 1999 Oxytocin-stimulated capacitative calcium entry in human myometrial cells. Am J Obstet Gynecol 181:424-429
46. Shlykov SG, Sanborn BM 2004 Stimulation of intracellular Ca2+ oscillations by diacylglycerol in human myometrial cells. Cell Calcium 36:157-164
47. Shlykov SG, Yang M, Alcorn JL, Sanborn BM 2003 Capacitative cation entry in human myometrial cells and augmentation by hTrpC3 overexpression. Biol Reprod 69:647-655
48. Yang M, Gupta A, Shlykov SG, Corrigan R, Tsujimoto S, Sanborn BM 2002 Multiple Trp isoforms implicated in capacitative calcium entry are expressed in human pregnant myometrium and myometrial cells. Biol Reprod 67:988-994
49. Zhong M, Ku CY, Sanborn BM 2005 Pathways used by relaxin to regulate myometrial phospholipase C. Ann NY Acad Sci 1041:300-304
50. Zhong M, Yang M, Sanborn BM 2003 Extracellular signal-regulated kinase 1/2 activation by myometrial oxytocin receptor involves Gα(q)Gβγ and epidermal growth factor receptor tyrosine kinase activation. Endocrinology 144:2947-2956
51. Hardy DB, Janowski BA, Corey DR, Mendelson CR 2006 Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-κB activation of cyclooxygenase 2 expression. Mol Endocrinol 20:2724-2733
52. Challis JRG, Matthews SG, Gibb W, Lye SJ 2000 Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev 21:514-550
53. Muttukrishna S, Fowler PA, George L, Groome NP, Knight PG 1996 Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J Clin Endocrinol Metab 81:3328-3334
54. O'Connor AE, McFarlane JR, Hayward S, Yohkaichiya T, Groome NP, de Kretser DM 1999 Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study. Hum Reprod 14:827-832
55. Fowler PA, Evans LW, Groome NP, Templeton A, Knight PG 1998 A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-αC and follistatin during pregnancy. Hum Reprod 13:3530-3536
56. Florio P, Severi FM, Luisi S, Ciarmela P, Calonaci G, Cobellis L, Petraglia F 2003 Endometrial expression and secretion of activin A, but not follistatin, increase in the secretory phase of the menstrual cycle. J Soc Gynecol Investig 10:237-243
57. Ciarmela P, Florio P, Sigurdardottir M, Toti P, Maguer-Satta V, Rimokh R, Altomare A, Tosi P, Petraglia F 2004 Follistatin-related gene expression, but not follistatin expression, is decreased in human endometrial adenocarcinoma. Eur J Endocrinol 151:251-257