메뉴 건너뛰기




Volumn 24, Issue 4, 2008, Pages 407-413

Glyceroneogenesis and PEPCK-C: Pharmacological targets in type 2 diabetes;Glycéronéogenèse et PEPCK-C: Cibles pharmacologiques dans le diabète de type 2

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; AMINO ACID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; FATTY ACID; GLUCOCORTICOID; GLYCEROPHOSPHATE; LACTIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVIC ACID; TRIACYLGLYCEROL;

EID: 42449089475     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2008244407     Document Type: Review
Times cited : (12)

References (35)
  • 1
    • 33846567550 scopus 로고    scopus 로고
    • From obesity to diabetes
    • Keller U. From obesity to diabetes. Int J Vitam Nutr Res 2006 ; 76 : 172-7.
    • (2006) Int J Vitam Nutr Res , vol.76 , pp. 172-177
    • Keller, U.1
  • 2
    • 0026468362 scopus 로고
    • What if Minkowski had been ageusic? An alternative angle on diabetes
    • McGarry J. D. What if Minkowski had been ageusic? An alternative angle on diabetes. Science 1992 ; 258 : 766-70.
    • (1992) Science , vol.258 , pp. 766-770
    • McGarry, J.D.1
  • 3
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963 ; 1 : 785-9.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 4
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 2000 ; 106 : 171-6.
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 5
    • 8844226709 scopus 로고    scopus 로고
    • Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
    • Zimmermann R, Strauss JG, Haemmerle G, et al. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 2004 ; 306 : 1383-6.
    • (2004) Science , vol.306 , pp. 1383-1386
    • Zimmermann, R.1    Strauss, J.G.2    Haemmerle, G.3
  • 7
    • 33947109987 scopus 로고    scopus 로고
    • The role ofperilipin in human obesity and insulin resistance
    • Tai ES, Ordovas JM. The role ofperilipin in human obesity and insulin resistance. Curr Opin Lipidol 2007 ; 18 : 152-6.
    • (2007) Curr Opin Lipidol , vol.18 , pp. 152-156
    • Tai, E.S.1    Ordovas, J.M.2
  • 8
    • 0001072302 scopus 로고
    • The production and release of glycerol by adipose tissue incubated in vitro
    • Vaughan M. The production and release of glycerol by adipose tissue incubated in vitro. J Biol Chem 1962 ; 237 : 3354-8.
    • (1962) J Biol Chem , vol.237 , pp. 3354-3358
    • Vaughan, M.1
  • 9
    • 0037805618 scopus 로고    scopus 로고
    • Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells
    • Tordjman J, Chauvet G, Quette J, et al. Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells. J Biol Chem 2003 ; 278 : 18785-90.
    • (2003) J Biol Chem , vol.278 , pp. 18785-18790
    • Tordjman, J.1    Chauvet, G.2    Quette, J.3
  • 10
    • 33744953147 scopus 로고    scopus 로고
    • Rosiglitazone controls fatty acid cycling in human adipose tissue by means of glyceroneogenesis and glycerol phosphorylation
    • Leroyer SN, Tordjman J, Chauvet G, et al. Rosiglitazone controls fatty acid cycling in human adipose tissue by means of glyceroneogenesis and glycerol phosphorylation. J Biol Chem 2006 ; 281 : 13141-9.
    • (2006) J Biol Chem , vol.281 , pp. 13141-13149
    • Leroyer, S.N.1    Tordjman, J.2    Chauvet, G.3
  • 11
    • 0014198482 scopus 로고
    • Phosphoenolpyruvate carboxykinase and the synthesis of glyceride-glycerol from pyruvate in adipose tissue
    • Ballard FJ, Hanson RW, Leveille GA. Phosphoenolpyruvate carboxykinase and the synthesis of glyceride-glycerol from pyruvate in adipose tissue. J Biol Chem 1967 ; 242 : 2746-50.
    • (1967) J Biol Chem , vol.242 , pp. 2746-2750
    • Ballard, F.J.1    Hanson, R.W.2    Leveille, G.A.3
  • 12
    • 0028866117 scopus 로고
    • Fatty acids and fibrates are potent inducers of transcription of the phosphenolpyruvate carboxykinase gene in adipocytes
    • Antras-Ferry J, Robin P, Robin D, Forest C. Fatty acids and fibrates are potent inducers of transcription of the phosphenolpyruvate carboxykinase gene in adipocytes. Eur J Biochem 1995 ; 234 : 390-6.
    • (1995) Eur J Biochem , vol.234 , pp. 390-396
    • Antras-Ferry, J.1    Robin, P.2    Robin, D.3    Forest, C.4
  • 13
    • 20644460348 scopus 로고    scopus 로고
    • Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C
    • Chakravarty K, Cassuto H, Reshef L, Hanson RW. Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C. Crit Rev Biochem Mol Biol 2005 ; 40 : 129-54.
    • (2005) Crit Rev Biochem Mol Biol , vol.40 , pp. 129-154
    • Chakravarty, K.1    Cassuto, H.2    Reshef, L.3    Hanson, R.W.4
  • 14
    • 0028988487 scopus 로고
    • PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
    • Tontonoz P, Hu E, Devine J, et al. PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol 1995 ; 15 : 351-7.
    • (1995) Mol Cell Biol , vol.15 , pp. 351-357
    • Tontonoz, P.1    Hu, E.2    Devine, J.3
  • 15
    • 0033532158 scopus 로고    scopus 로고
    • Adipose expression of the phosphoenolpyruvate carboxykinase promoter requires peroxisome proliferator-activated receptor gamma and 9-cis-retinoic acid receptor binding to an adipocyte-specific enhancer in vivo
    • Devine JH, Eubank DW, Clouthier DE, et al. Adipose expression of the phosphoenolpyruvate carboxykinase promoter requires peroxisome proliferator-activated receptor gamma and 9-cis-retinoic acid receptor binding to an adipocyte-specific enhancer in vivo. J Biol Chem 1999 ; 274 : 13604-12.
    • (1999) J Biol Chem , vol.274 , pp. 13604-13612
    • Devine, J.H.1    Eubank, D.W.2    Clouthier, D.E.3
  • 17
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
    • Okuno A, Tamemoto H, Tobe K, et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest 1998 ; 101 : 1354-61.
    • (1998) J Clin Invest , vol.101 , pp. 1354-1361
    • Okuno, A.1    Tamemoto, H.2    Tobe, K.3
  • 18
    • 33845299821 scopus 로고    scopus 로고
    • Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells
    • Crossno JT Jr, Majka SM, Grazia T, et al. Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. J Clin Invest 2006 ; 116 : 3220-8.
    • (2006) J Clin Invest , vol.116 , pp. 3220-3228
    • Crossno Jr, J.T.1    Majka, S.M.2    Grazia, T.3
  • 19
    • 1842454705 scopus 로고    scopus 로고
    • Adipose tissue and adipakines : For better or worse
    • Guerre-Millo M. Adipose tissue and adipakines : for better or worse. Diabetes Metab 2004 ; 30 : 13-9.
    • (2004) Diabetes Metab , vol.30 , pp. 13-19
    • Guerre-Millo, M.1
  • 20
    • 0035214264 scopus 로고    scopus 로고
    • A single element in the phosphoenolpyruvate carboxykinase gene mediates thiazolidinedione action specifically in adipocytes
    • Glorian M, Duplus E, Beale EG, et al. A single element in the phosphoenolpyruvate carboxykinase gene mediates thiazolidinedione action specifically in adipocytes. Biochimie 2001 ; 83 : 933-43.
    • (2001) Biochimie , vol.83 , pp. 933-943
    • Glorian, M.1    Duplus, E.2    Beale, E.G.3
  • 21
    • 0346040239 scopus 로고    scopus 로고
    • Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue : Induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes
    • Duplus E, Benelli C, Reis AF, et al. Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue : induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes. Biochimie 2003 ; 85 : 1257-64.
    • (2003) Biochimie , vol.85 , pp. 1257-1264
    • Duplus, E.1    Benelli, C.2    Reis, A.F.3
  • 22
    • 15444347751 scopus 로고    scopus 로고
    • Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat
    • Hallakou S, Doare L, Foufelle F, et al. Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat. Diabetes 1997 ; 46 : 1393-9.
    • (1997) Diabetes , vol.46 , pp. 1393-1399
    • Hallakou, S.1    Doare, L.2    Foufelle, F.3
  • 23
    • 33846782591 scopus 로고    scopus 로고
    • Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes
    • Cadoudal T, Blouin JM, Collinet M, et al. Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes. Diabetologia 2007 ; 50 : 666-75.
    • (2007) Diabetologia , vol.50 , pp. 666-675
    • Cadoudal, T.1    Blouin, J.M.2    Collinet, M.3
  • 24
    • 14644415905 scopus 로고    scopus 로고
    • Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients
    • Boden G, Homko C, Mozzoli M, et al. Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients. Diabetes 2005 ; 54 : 880-5.
    • (2005) Diabetes , vol.54 , pp. 880-885
    • Boden, G.1    Homko, C.2    Mozzoli, M.3
  • 25
    • 0035501248 scopus 로고    scopus 로고
    • Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone : A peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism
    • Davies GF, Khandelwal RL, Wu L, et al. Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone : a peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism. Biochem Pharmacol 2001 ; 62 : 1071-9.
    • (2001) Biochem Pharmacol , vol.62 , pp. 1071-1079
    • Davies, G.F.1    Khandelwal, R.L.2    Wu, L.3
  • 26
    • 0036797450 scopus 로고    scopus 로고
    • A futile metabolic cycle activated in adipocytes by antidiabetic agents
    • Guan HP, Li Y, Jensen W, et al. A futile metabolic cycle activated in adipocytes by antidiabetic agents. Nat Med 2002 ; 8 : 1122-8.
    • (2002) Nat Med , vol.8 , pp. 1122-1128
    • Guan, H.P.1    Li, Y.2    Jensen, W.3
  • 27
    • 0038379389 scopus 로고    scopus 로고
    • A "futile cycle" induced by thiazolidinediones in human adipose tissue?
    • Tan GD, Debard C, Tiraby C, et al. A "futile cycle" induced by thiazolidinediones in human adipose tissue? Nat Med 2003 ; 9 : 811-2.
    • (2003) Nat Med , vol.9 , pp. 811-812
    • Tan, G.D.1    Debard, C.2    Tiraby, C.3
  • 28
    • 0028888291 scopus 로고
    • Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells : Opposite effects of dexamethasone and isoprenaline on transcription
    • Franckhauser S, Antras-Ferry J, Robin P, et al. Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells : opposite effects of dexamethasone and isoprenaline on transcription. Biochem J 1995 ; 305 : 65-71.
    • (1995) Biochem J , vol.305 , pp. 65-71
    • Franckhauser, S.1    Antras-Ferry, J.2    Robin, P.3
  • 29
    • 0036234051 scopus 로고    scopus 로고
    • Evidence for selective induction of phosphoenolpyruvate carboxykinase gene expression by unsaturated and nonmetabolized fatty acids in adipocytes
    • Duplus E, Glorian M, Tordjman J, et al. Evidence for selective induction of phosphoenolpyruvate carboxykinase gene expression by unsaturated and nonmetabolized fatty acids in adipocytes. J Cell Biochem 2002 ; 85 : 651-61.
    • (2002) J Cell Biochem , vol.85 , pp. 651-661
    • Duplus, E.1    Glorian, M.2    Tordjman, J.3
  • 30
    • 0036709899 scopus 로고    scopus 로고
    • Is there a single mechanism for fatty acid regulation of gene transcription?
    • Duplus E, Forest C. Is there a single mechanism for fatty acid regulation of gene transcription? Biochem Pharmacol 2002 ; 64 : 893-901.
    • (2002) Biochem Pharmacol , vol.64 , pp. 893-901
    • Duplus, E.1    Forest, C.2
  • 31
    • 3042760032 scopus 로고    scopus 로고
    • The effect of pioglitazone on peroxisome proliferator-activated receptor-gamma target genes related to lipid storage in vivo
    • Bogacka I, Xie H, Bray GA, Smith SR. The effect of pioglitazone on peroxisome proliferator-activated receptor-gamma target genes related to lipid storage in vivo. Diabetes Care 2004 ; 27 : 1660-7.
    • (2004) Diabetes Care , vol.27 , pp. 1660-1667
    • Bogacka, I.1    Xie, H.2    Bray, G.A.3    Smith, S.R.4
  • 32
    • 0346144568 scopus 로고    scopus 로고
    • Indication for genetic linkage of the phosphoenolpyruvate carboxykinase (PCK1) gene region on chromosome 20q to non-insulin-dependent diabetes mellitus
    • El Hani H, Zouali H, Philippi A, et al. Indication for genetic linkage of the phosphoenolpyruvate carboxykinase (PCK1) gene region on chromosome 20q to non-insulin-dependent diabetes mellitus. Diabetes Metab 1996 ; 22 : 451-4.
    • (1996) Diabetes Metab , vol.22 , pp. 451-454
    • El Hani, H.1    Zouali, H.2    Philippi, A.3
  • 33
    • 1442278755 scopus 로고    scopus 로고
    • Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus
    • Cao H, Van der Veer E, Ban BR, et al. Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus. J Clin Endocrinol Metab 2004 ; 89 : 898-903.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 898-903
    • Cao, H.1    Van der Veer, E.2    Ban, B.R.3
  • 34
    • 36348972777 scopus 로고    scopus 로고
    • Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse
    • Hakimi P, Yang J, Casadesus G, et al. Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J Biol Chem 2007 ; 282 : 328-44.
    • (2007) J Biol Chem , vol.282 , pp. 328-344
    • Hakimi, P.1    Yang, J.2    Casadesus, G.3
  • 35
    • 0141650781 scopus 로고    scopus 로고
    • Rôle des acides gras libres dans la sécré tion et l'action de l'insuline : Mécanismes de la lipotoxicité.
    • Girard J. Rôle des acides gras libres dans la sécré tion et l'action de l'insuline : mécanismes de la lipotoxicité. Med Sci (Paris) 2003 ; 19 : 827-33.
    • (2003) Med Sci (Paris) , vol.19 , pp. 827-833
    • Girard, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.