P2X receptor activation elicits transporter-mediated noradrenaline release from rat hippocampal slices

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 3, 2004, Pages 973-980

  Papp, Lilla ^a   Balázsa, Tamás ^a   Köfalvi, Attila ^b   Erdélyi, Ferenc ^a   Szabó, Gábor ^a   Vizi, E Sylvester ^a   Sperlágh, Beáta ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; 3,7 DIMETHYL 1 PROPARGYLXANTHINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE TRIPHOSPHATE; BRILLIANT BLUE; CHOLINE; DESIPRAMINE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL; MESSENGER RNA; NF 023; NF 449; NORADRENALIN; NORADRENALIN TRANSPORTER; PERTUSSIS TOXIN; PURINE P2X RECEPTOR; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X4 RECEPTOR; PURINE P2X5 RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y2 RECEPTOR; PURINE P2Y4 RECEPTOR; PURINE P2Y6 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SODIUM ION; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN STEM; CATECHOLAMINE NERVE CELL; CELL PH; CHANNEL GATING; CONTROLLED STUDY; HIPPOCAMPUS; MALE; NONHUMAN; NORADRENALIN RELEASE; NUCLEOTIDE SEQUENCE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HIPPOCAMPUS; MALE; NOREPINEPHRINE; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 4243116404     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.066712     Document Type: Article

References (40)

1. Boehm S (1999) ATP stimulates sympathetic transmitter release via presynaptic P2X purinoceptors. J Neurosci 19:737-746.
2. Boehm S and Kubista H (2002) Fine tuning of sympathetic transmitter release via ionotropic and metabotropic presynaptic receptors. Pharmacol Rev 54:43-99.
3. 6-methyl 2′-deoxyadenosine 3′,5′-bisphosphate. Br J Pharmacol 124:1-3.
4. 1 receptors. Naunyn Schmiedebergs Arch Pharmacol 364:285-290.
5. 1/2 receptors show a novel sensitivity to extracellular pH. J Pharmacol Exp Ther 300:673-680.
6. Chambers JK, Macdonald LE, Sarau HM, Ames RS, Freeman K, Foley JJ, Zhu Y, McLaughlin MM, Murdock P, McMillan L, et al. (2000) A G protein-coupled receptor for UDP-glucose. J Biol Chem 275:10767-10771.
7. 7 receptor. Neuropharmacology 36:1277-1283.
8. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J Neurosci 16:2495-2507.
9. Cunha RA (2001) Regulation of the ecto-nucleotidase pathway in rat hippocampal nerve terminals. Neurochem Res 26:979-991.
10. 1 receptors. J Neurosci 18:1987-1995.
11. Dunn PM, Zhong Y, and Burnstock G (2001) P2X receptors in peripheral neurons. Prog Neurobiol 65:107-134.
12. Fredholm BB, Ijzerman AP, Jacobson KA, Klotz KN, and Linden J (2001) International Union of Pharmacology: XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53:527-552.
13. Frohlich R, Boehm S, and Illes P (1996) Pharmacological characterization of P2 purinoceptor types in rat locus coeruleus neurons. Eur J Pharmacol 315:255-261.
14. Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, et al. (2001) Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature (Lond) 409:202-207.
15. 7 receptors. Mol Pharmacol 58:82-88.
16. Jonzon B and Fredholm BB (1984) Adenosine receptor mediated inhibition of noradrenaline release from slices of the rat hippocampus. Life Sci 35:1971-1979.
17. Khakh BS, Gittermann D, Cockayne DA, and Jones A (2003) ATP modulation of excitatory synapses onto interneurons. J Neurosci 23:7426-7437.
18. Kidd EJ, Grahames CB, Simon J, Michel AD, Barnard EA, and Humphrey PP (1995) Localization of P2X purinoceptor transcripts in the rat nervous system. Mol Pharmacol 48:569-573.
19. Koch H, Kugelgen I, and Starke K (1997) P2-receptor-mediated inhibition of noradrenaline release in the rat hippocampus. Naunyn Schmiedebergs Arch Pharmacol 355:707-715.
20. 6 channel subunits coassemble into a novel heteromeric ATP receptor. J Neurosci 18:7152-7159.
21. Moore DJ, Chambers JK, Wahlin JP, Tan KB, Moore GB, Jenkins O, Emson PC, and Murdock PR (2001) Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study. Biochim Biophys Acta 1521:107-119.
22. 1 purinergic receptor in neurons and glial cells of the central nervous system. Mol Brain Res 78:50-58.
23. Norenberg W, Gobel I, Meyer A, Cox SL, Starke K, and Trendelenburg AU (2001) Stimulation of mouse cultured sympathetic neurons by uracil but not adenine nucleotides. Neuroscience 103:227-236.
24. North RA (2002) Molecular physiology of P2X receptors. Physiol Rev 82:1013-1067.
25. Oleskevich S, Descarries L, and Lacaille JC (1989) Quantified distribution of the noradrenaline innervation in the hippocampus of adult rat. J Neurosci 9:3803-3815.
26. Pittaluga A and Raiteri M (1992) N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release: I. Location on axon terminals and pharmacological characterization. J Pharmacol Exp Ther 260:232-237.
27. Poelchen W, Sieler D, Wirkner K, and Illes P (2001) Co-transmitter function of ATP in central catecholaminergic neurons of the rat. Neuroscience 102:593-602.
28. Queiroz G, Talaia C, and Goncalves J (2003) ATP modulates noradrenaline release by activation of inhibitory P2Y receptors and facilitatory P2X receptors in the rat vas deferens. J Pharmacol Exp Ther 307:809-815.
29. Sántha E, Sperlágh B, Zelles T, Zsilla G, Tóth PT, Lendvai B, Baranyi M, and Vizi ES (2000) Multiple cellular mechanisms mediate the effect of lobeline on the release of norepinephrine. J Pharmacol Exp Ther 294:302-307.
30. Soto F, Lambrecht G, Nickel P, Stuhmer W, and Busch AE (1999) Antagonistic properties of the suramin analogue NF023 at heterologously expressed P2X receptors. Neuropharmacology 38:141-149.
31. 2X-receptors located on axon terminals. Br J Pharmacol 131:1775-1783.
32. 7 receptors in the regulation of neurotransmitter release in the rat hippocampus. JNeurochem 81:1196-1211.
33. 2-adrenoceptors. Neuroscience 82:511-520.
34. Sperlágh B, Szabó G, Erdélyi F, Baranyi M, and Vizi ES (2003) Homo- and heteroexchange of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system. Br J Pharmacol 139:623-633.
35. Torres GE, Egan TM, and Voigt MM (1999) Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners. J Biol Chem 274:6653-6659.
36. von Kugelgen I and Wetter A (2000) Molecular pharmacology of P2Y-receptors. Naunyn Schmiedebergs Arch Pharmacol 362:310-323.
37. 4 receptor. J Neurochem 71:1348-1357.
38. 1 messenger RNA within the chick brain. Neuroscience 84:825-837.
39. Yoshioka K, Saitoh O, and Nakata H (2001) Heteromeric association creates a P2Y-like adenosine receptor. Proc Natl Acad Sci USA 98:7617-7622.
40. alphai-coupled ADP receptor from human and mouse. J Pharmacol Exp Ther 301:705-713.