Inhibition by ATP of hippocampal synaptic transmission requires localized extracellular catabolism by ecto-nucleotidases into adenosine and channeling to adenosine A1 receptors

Journal of Neuroscience

Volumn 18, Issue 6, 1998, Pages 1987-1995

  Cunha, Rodrigo A ^a   Sebastião, Ana M ^a   Ribeiro, J A ^a  

^a UNIVERSITY OF LISBON   (Portugal)

Author keywords

A1 receptors; Adenosine; ATP; ATP analogs; Ecto nucleotidases; Hippocampus; P2 receptors

Indexed keywords

5' NUCLEOTIDASE INHIBITOR; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE DEAMINASE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; DIPYRIDAMOLE; PURINE P2 RECEPTOR; PURINE P2 RECEPTOR ANTAGONIST; SURAMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; EXTRACELLULAR SPACE; HIPPOCAMPUS; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; REGULATORY MECHANISM; SYNAPTIC TRANSMISSION;

EID: 0032521330     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-06-01987.1998     Document Type: Article

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