An overview on applications of optical spectroscopy in cervical cancers

Journal of Cancer Research and Therapeutics

Volumn 4, Issue 1, 2008, Pages 26-36

  Chilakapati, Murali ^a,c   Sockalingum, G ^b   Vidyasagar, M ^a   Manfait, M ^b   Fernanades, Donald ^a   Vadhiraja, B ^a   Maheedhar, K ^a  

^a MANIPAL UNIVERSITY   (India)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^c TMC   (India)

Author keywords

Cervix cancers; Fluorescence; FTIR; Optical diagnosis; Raman spectroscopy

Indexed keywords

ADVANCED CANCER; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER RESISTANCE; CANCER SCREENING; COLPOSCOPY; FLUORESCENCE SPECTROSCOPY; GOLD STANDARD; HISTOPATHOLOGY; HUMAN; PAPANICOLAOU TEST; RADIATION RESPONSE; RADIOSENSITIVITY; RAMAN SPECTROMETRY; REVIEW; SPECTROSCOPY; UTERINE CERVIX CANCER;

EID: 42349106355     PISSN: 09731482     EISSN: 19984138     Source Type: Journal    
DOI: 10.4103/0973-1482.39602     Document Type: Review

References (103)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics. CA Cancer Clin 2005;55:74-108.
2. Kjellberg L, Hallmans G, Mahadevan-Jansen A, Johansson R, Bergman F, Wodell G, et al. Smoking, diet, pregnancy and oral contraceptives use as cervical intra epithelial neoplasia in relation to Human Papilloma virus infection. Br J Cancer 2000;82:1332-8.
3. Notani PN. Global variation in cancer incidence and mortality. Curr Sci 2001;81:465-74.
4. Mitchell MF. Accuracy of colposcopy. Consult Obstet Gynecol 1994;6:70-3.
5. Koss LG. The Papanicolaou test for cervical cancer detection: A triumph and a tragedy. J Am Med Assoc 1989;261:737-45.
6. Jadhav GK, Bhanumathi P, Uma Devi P, Seetharamaiah T, Vidyasagar MS, Koteshwar Rao K, et al. Possible role of glutathione in predicting radiotherapy response of cervix cancer. Int J Radiat Oncol Biol Phys 1998;41:3-5.
7. Russo A, Mitchell JB, Finkelstein E, DeGraff WG, Spiro IJ, Gamson J. The effects of cellular glutathione elevation on the oxygen enhancement ratio. Radiat Res 1985;103:232-9.
8. Bhattathiri VN, Sreelekha TT, Sebastian P, Remani P, Chandini R, Vijayakumar T, et al. Influence of plasma GSH level on acute radiation mucositis of the oral cavity. Int J Radiat Oncol Biol Phys 1994;29:383-6.
9. World Health Organization. WHO handbook for reporting results of cancer treatment. WHO offset publication no. 48. World Health Organization: Geneva; 1979.
10. Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000;92:205-16.
11. Ohara K, Oki A, Tanaka YO, Onishi K, Fukumitsu N, Hashimoto T, et al. Early determination of uterine cervical squamous cell carcinoma radioresponse identifies high- and low-response tumors. Int J Radiat Oncol Biol Phys 2006;64:1179-82.
12. Nakano T, Oka K, Ishikawa A, Morita S. Immunohistochemical prediction of radiation response and local control in radiation therapy for cervical cancer. Cancer Detect Prev 1998;22:120-8.
13. Bolger BS, Symonds RP, Stanton PD, MacLean AB, Burnett R, Kelly P, et al. Prediction of radiotherapy response of cervical carcinoma through measurement of proliferation rate. Br J Cancer 1996;74:1223-6.
14. Rofstad EK. NMR spectroscopy in prediction and monitoring of radiation response of tumors in vivo. Int J Radiat Biol 1990;57:1-5.
15. Kortum RR. Quantitative optical spectroscopy for tissue diagnosis. Ann Rev Phys Chem 1996;47:555-606.
16. Wagnieres GA, Star WM, Wilson BC. In vivo fluorescence spectroscopy and imaging for oncological applications. Photochem Photobiol 1998;68:603-32.
17. Haringsma J, Tytgat GN. Fluorescence and autofluorescence. Baillieres Best Pract Res Clin Gastroenterol 1999;13:1-10.
18. Ramanujam N. Fluorescence spectroscopy of neoplastic and nonneoplastic tissues. Neoplasia 2000;2:89-117.
19. Sokolov K, Follen M, Kortum RR. Optical spectroscopy for detection of neoplasia. Curr Opin Chem Biol 2002;6:651-8.
20. Mayinger B. Endoscopic fluorescence spectroscopic imaging in the gastrointestinal tract. Gastrointest Endosc Clin N Am 2004;14:487-505.
21. De Veld DC, Witjes MJ, Sterenborg HJ, Roodenburg JL. The status of in vivo autofluorescence spectroscopy and imaging for oral oncology. Oral Oncol 2005;41:117-31.
22. Kartha VB, Kurien J, Pai KM, Rao L, Rai L, Mahato KK, et al. Diagnosis at the molecular level:Analytical laser spectroscopy for clinical applications, Photo/Electrochemistry and Photobiology in the Environment, Energy and Fuel, 2005;153-221.
23. Lacroix M, Poinsot V, Fournier C, Couderc F. Laser-induced fluorescence detection schemes for the analysis of proteins and peptides using capillary electrophoresis. Electrophoresis 2005;26:2608-21.
24. Aaron JJ, Trajkovska S. Fluorescence studies of anti-cancer drugs-analytical and biomedical applications. Curr Drug Targets 2006;7:1067-81.
25. Markovich RJ, Pidgeon C. Introduction to Fourier transform infrared spectroscopy and applications in the pharmaceutical sciences. Pharm Res 1991;8:663-75.
26. Franck P, Nabet P, Dousset B. Applications of infrared spectroscopy to medical biology. Cell Mol Biol (Noisy-le-grand) 1998;44:273-5.
27. Sahu RK, Mordechai S. Fourier Transform infrared spectroscopy in cancer detection. Future Oncol 2005;1:635-7.
28. Murali Krishna C, Kegelaer G, Adt I, Rubin S, Kartha VB, Manfait M, et al. Combined fourier transform infrared and Raman spectroscopic approach for identification of multidrug resistance phenotype in cancer cell lines. Biopolymers 2006;82:462-70.
29. Bonnier F, Rubin S, Venteo L, Murali Krishna C, Pluot M, Baehrel B, et al. In-vitro analysis of normal and aneurismal human ascending aortic tissues using FTIR microspectroscopy. Biochim Biophys Acta 2006;1758:968-73.
30. Murali Krishna C, Sockalingum GD, Bhat RA, Venteo L, Kushtagi P, Pluot M, et al. FTIR and Raman microspectroscopy of normal, benign and malignant formalin-fixed ovarian tissues. Anal Bioanal Chem 2007;387:1649-56.
31. Hanlon EB, Manoharan R, Koo TW, Shafer KE, Motz JT, Fitzmaurice M, et al. Prospects for in vivo Raman spectroscopy. Phys Med Biol 2000;45:R1-59.
32. Choo-Smith LP, Edwards HG, Endtz HP, Kros JM, Heule F, Barr H, et al. Medical applications of Raman spectroscopy: From proof of principle to clinical implementation. Biopolymers 2002;67:1-9.
33. Murali Krishna C, Sockalingum GD, Kurien J, Rao L, Venteo L, Pluot M, et al. Micro-Raman spectroscopy for optical pathology of oral squamous cell carcinoma. Appl Spectrosc 2004;58:1128-35.
34. Murali Krishna C, Sockalingum GD, Venteo L, Bhat RA, Kushtagi P, Pluot M, et al. Evaluation of the suitability of ex vivo handled ovarian tissues for optical diagnosis by Raman microspectroscopy. Biopolymers 2005;79:269-76.
35. Krafft C, Sergo V. Biomedical applications of Raman and infrared spectroscopy to diagnose tissues. Spectroscopy 2006;20:195-218.
36. Lin SY, Li MJ, Cheng WT. FTIR and Raman vibrational microspectroscopies used for spectral biodiagnosis of human tissues. Spectroscopy 2007;21:1-30.
37. Alfano RR, Tata DB, Cordero J, Tomashefsky P, Longo FW, Alfano MA. Laser induced flourescence spectroscopy from native cancerous and normal tissue. IEEE J Quant Elect 1984;20:1507-11.
38. Mahadevan- Jasen A, Mitchell MF, Silva E, Thomsen S, Kortum RR. Study of the fluorescence properties of normal and neoplastic human cervical tissue. Lasers Surg Med 1993;13:647-55.
39. Ramanujam N, Mitchell MF, Mahadevan-Jasen A, Thomsen S, Silva E, Kortum RR. Fluorescence spectroscopy: A diagnostic tool for cervical intraepithelial neoplasia (CIN). Gynecol Oncol 1994;52:31-8.
40. Ramanujam N, Mitchell MF, Mahadevan-Jasen A, Warren S, Thomsen S, Silva E, et al. In vivo diagnosis of cervical intraepithelial neoplasia using 337-nm-excited laser-induced fluorescence. Proc Natl Acad Sci USA 1994;91:10193-7.
41. Atkinson EN, Mitchell MF, Ramanujam N, Kortum RR. Statistical techniques for diagnosing CIN using fluorescence spectroscopy: SVD and CART. J Cell Biochem Suppl 1995;23:125-30.
42. Ramanujam N, Mitchell MF, Mahadevan-Jasen A, Thomsen S, Malpica A, Wright T, et al. Development of a multivariate statistical algorithm to analyze human cervical tissue fluorescence spectra acquired in vivo. Lasers Surg Med 1996;19:46-62.
43. Mitchell MF, Cantor SB, Brookner C, Utzinger U, Schottenfeld D, Kortum RR. Screening for squamous intraepithelial lesions with fluorescence spectroscopy. Obstet Gynecol 1999;94:889-96.
44. Mitchell MF, Cantor SB, Ramanujam N, Tortolero-Luna G, Kortum RR. Fluorescence spectroscopy for diagnosis of squamous intraepithelial lesions of the cervix. Obstet Gynecol 1999;93:462-70.
45. Drezek R, Sokolov K, Utzinger U, Boiko I, Malpica A, Follen M, et al. Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: Modeling, measurements and implications. J Biomed Opt 2001;6:385-96.
46. Georgakoudi I, Jacobson BC, Müller MG, Sheets EE, Badizadegan K, Carr-Locke DL, et al. NAD(P)H and collagen as in vivo quantitative fluorescent biomarkers of epithelial precancerous changes. Cancer Res 2002;62:682-7.
47. Chang SK, Dawood MY, Staerkel G, Utzinger U, Atkinson EN, Kortum RR, et al. Fluorescence spectroscopy for cervical precancer detection:Is there variance across the menstrual cycle? J Biomed Opt 2002;7:595-602.
48. Cox DD, Chang SK, Dawood MY, Staerkel G, Utzinger U, Kortum RR, et al. Detecting the signal of the menstrual cycle in fluorescence spectroscopy of the cervix. Appl Spectrosc 2003;57:67-72.
49. Brookner C, Utzinger U, Follen M, Kortum RR, Cox D, Atkinson EN. Effects of biographical variables on cervical fluorescence emission spectra. J Biomed Opt 2003;8:479-83.
50. Freeberg JA, Serachitopol DM, McKinnon N, Price R, Atkinson EN, Cox DD, et al. Fluorescence and reflectance device variability throughout the progression of a phase II clinical trial to detect and screen for cervical neoplasia using a fiber optic probe. J Biomed Opt 2007;12:034015.
51. Chang SK, Mirabal YN, Atkinson EN, Cox D, Malpica A, Follen M, et al. Combined reflectance and fluorescence spectroscopy for in vivo detection of cervical pre-cancer. J Biomed Opt 2005;10:024031.
52. Lee JS, Shuhatovich O, Price R, Pikkula B, Follen M, McKinnon N, et al. Design and preliminary analysis of a study to assess intra-device and inter-device variability of fluorescence spectroscopy instruments for detecting cervical neoplasia. Gynecol Oncol 2005;99:S98-S111.
53. Pikkula BM, Shuhatovich O, Price RL, Serachitopol DM, Follen M, McKinnon N, et al. Instrumentation as a source of variability in the application of fluorescence spectroscopic devices for detecting cervical neoplasia. Biomed Opt 2007;12:034014.
54. Milbourne A, Park SY, Benedet JL, Miller D, Ehlen T, Rhodes H, et al. Results of a pilot study of multispectral digital colposcopy for the in vivo detection of cervical intraepithelial neoplasia. Gynecol Oncol 2005;99:S67-75.
55. Georgakoudi I, Sheets EE, Müller MG, Backman V, Crum CP, Badizadegan K, et al. Trimodal spectroscopy for the detection and characterization of cervical precancers in vivo. Cancer Res 2002;62:682-7.
56. Schomacker KT, Meese TM, Jiang C, Abele CC, Dickson K, Sum ST, et al. Novel optical detection system for in vivo identification and localization of cervical intraepithelial neoplasia. J Biomed Opt 2006;11:34009.
57. Majumder SK, Uppal A, Gupta PK. In-vitro diagnosis of human uterine malignancy using N2 laser induced autofluorescence spectroscopy. Curr Sci 1996;70:833-6.
58. Chidananda SM, Satyamoorthy K, Rai L, Manjunath AP, Kartha VB. Optical diagnosis of cervical cancer by fluorescence spectroscopy technique. Int J Cancer 2006;119:139-45.
59. Palsson S, Stenram U, Thompson MS, Vaitkuviene A, Poskiene V, Ziobakiene R, et al. Methods for detailed histopathological investigation and localization of biopsies from cervix uteri to improve the interpretation of autofluorescence data. J Environ Pathol Toxicol Oncol 2006;25:321-40.
60. DeSantis T, Chakhtoura N, Twiggs L, Ferris D, Lashgari M, Flowers L, et al. Spectroscopic imaging as a triage test for cervical disease: a prospective multicenter clinical trial. J Low Genit Tract Dis 2007;11:18-24.
61. Wu Y, Zheng W, Qu JY. Sensing cell metabolism by time-resolved autofluorescence. Opt Lett 2006;31:3122-4.
62. Alvarez RD, Wright TC; Optical Detection Group. Effective cervical neoplasia detection with a novel optical detection system: A randomized trial. Gynecol Oncol 2007;104:281-9.
63. Martin SF, Wood AD, McRobbie MM, Mazilu M, McDonald MP, Samuel ID, et al. Fluorescence spectroscopy of an in vitro model of human cervical precancer identifies neoplastic phenotype. Int J Cancer 2007;120:1964-70.
64. Werner CL, Griffith WF, Ashfaq R, Gossett D, Wilkinson E, Raab S, et al. Comparison of human papilloma virus testing and spectroscopy combined with cervical cytology for the detection of high-grade cervical neoplasia. J Low Genit Tract Dis 2007;11:73-9.
65. Wong PT, Wong K, Fung Kee Fung M. Pressure-tuning FTIR study of human cervical tissues. Appl Spectroscopy 1993;47:1058-63.
66. Yazdi HM, Bertrand MA, Wong PT. Detecting structural changes at the molecular level with Fourier transform infrared spectroscopy: A potential tool for prescreening preinvasive lesions of the cervix. Acta Cytol 1996;40:664-8.
67. Morris BJ, Lee C, Nightingale BN, Molodysky E, Morris LJ, Appio R, et al. Fourier transform infrared spectroscopy of dysplastic, papillomavirus-positive cervicovaginal lavage specimens. Gynecol Oncol 1995;56:245-9.
68. Fung Kee Fung M, Senterman M, Eid P, Faught W, Mikhael NZ, Wong PT. Comparison of Fourier-transform infrared spectroscopic screening of exfoliated cervical cells with standard Papanicolaou screening. Gynecol Oncol 1997;66:10-5.
69. Cohenford MA, Godwin TA, Cahn F, Bhandare P, Caputo TA, Rigas B. Infrared spectroscopy of normal and abnormal cervical smears: Evaluation by principal component analysis. Gynecol Oncol 1997;66:59-65.
70. Sindhuphak R, Issaravanich S, Udomprasertgul V, Srisookho P, Warakamin S, Sindhuphak S, et al. A new approach for the detection of cervical cancer in Thai women. Gynecol Oncol 2003;90:10-4.
71. Chiriboga L, Xie P, Yee H, Zarou D, Zakim D, Diem M. Infrared spectroscopy of human tissue. IV. Detection of dysplastic and neoplastic changes of human cervical tissue via infrared microscopy. Cell Mol Biol (Noisy-le-grand) 1998;44:219-29.
72. Miljkovic M, Romeo M, Matthäus C, Diem M. Infrared microspectroscopy of individual human cervical cancer (HeLa) cells suspended in growth medium. Biopolymers 2004;74:172-5.
73. Romeo M, Matthäus C, Miljkovic M, Diem M. Infrared microspectroscopy of individual human cervical cancer (HeLa) cells. Biopolymers 2004;74:168-71.
74. Boydston-White S, Romeo M, Chernenko T, Regina A, Miljković M, Diem M. Cell-cycle-dependent variations in FTIR micro-spectra of single proliferating HeLa cells: Principal component and artificial neural network analysis. Biochim Biophys Acta 2006;1758:908-14.
75. Diem M, Romeo M, Boydston-White S, Miljkovic M, Matthaus C. A decade of vibrational micro-spectroscopy of human cells and tissue (1994-2004). Analyst 2004;129:880-5.
76. Chiriboga L, Yee H, Diem M, Wood B. Infrared spectral features of exfoliated cervical cells, cervical adenocarcinoma tissue and an adenocarcinoma cell line (SiSo). Gynecol Oncol 2002;85:170-4.
77. Wood BR, Chiriboga L, Yee H, Quinn MA, McNaughton D, Diem M. Fourier transform infrared (FTIR) spectral mapping of the cervical transformation zone and dysplastic squamous epithelium. Gynecol Oncol 2004;93:59-68.
78. Mourant JR, Gibson RR, Johnson TM, Carpenter S, Short KW, Yamada YR, et al. Methods for measuring the infrared spectra of biological cells. Phys Med Biol 2003;48:243-57.
79. Wood BR, Quinn MA, Tait B, Ashdown M, Hislop T, Romeo M, et al. FTIR microspectroscopic study of cell types and potential confounding variables in screening for cervical malignancies. Biospectroscopy 1998;4:75-91.
80. Romeo MJ, Wood BR, Quinn MA, McNaughton D. Removal of blood components from cervical smears: Implications for cancer diagnosis using FTIR spectroscopy. Biopolymers 2003;72:69-76.
81. Shaw RA, Guijon FB, Paraskevas M, Ying SL, Mantsch HH. Infrared spectroscopy of exfoliated cervical cell specimens: Proceed with caution. Anal Quant Cytol Histol 1999;21:292-302.
82. Chang JI, Huang YB, Wu PC, Chen CC, Huang SC, Tsai YH. Characterization of human cervical precancerous tissue through the fourier transform infrared microscopy with mapping method. Gynecol Oncol 2003;91:577-83.
83. Mark S, Sahu RK, Kantarovich K, Podshyvalov A, Guterman H, Goldstein J, et al. Fourier transform infrared microspectroscopy as a quantitative diagnostic tool for assignment of premalignancy grading in cervical neoplasia. J Biomed Opt 2004;9:558-67.
84. Mordechai S, Sahu RK, Hammody Z, Mark S, Kantarovich K, Guterman H, et al. Possible common biomarkers from FTIR microspectroscopy of cervical cancer and melanoma. J Microsc 2004;215:86-91.
85. Podshyvalov A, Sahu RK, Mark S, Kantarovich K, Guterman H, Goldstein J, et al. Distinction of cervical cancer biopsies by use of infrared microspectroscopy and probabilistic neural networks. Appl Opt 2005;44:3725-34.
86. Walsh MJ, Singh MN, Pollock HM, Cooper LJ, German MJ, Stringfellow HF, et al. ATR microspectroscopy with multivariate analysis segregates grades of exfoliative cervical cytology. Biochem Biophys Res Commun 2007;352:213-9.
87. Mahadevan-Jansen A, Mitchell MF, Ramanujam N, Malpica A, Thomsen S, Utzinger U, et al. Near-infrared Raman spectroscopy for in vitro detection of cervical precancers. Photochem Photobiol 1998;68:123-32.
88. Mahadevan-Jansen A, Mitchell MF, Ramanujam N, Utzinger U, Kortum RR. Development of a fiber optic probe to measure NIR Raman spectra of cervical tissue in vivo. Photochem Photobiol 1998;68:427-31.
89. Utzinger UR, Heintzelman DL, Mahadevan-Jansen A, Malpica A, Michele Follen, Kortum RR. Near-infrared Raman spectroscopy for in vivo detection of cervical precancers. Appl Spectroscopy, 1998;55:955-9.
90. Lyng FM, Faoláin EO, Conroy J, Meade AD, Knief P, Duffy B, et al. Vibrational spectroscopy for cervical cancer pathology, from biochemical analysis to diagnostic tool. Exp Mol Pathol 2007;82:121-9.
91. Murali Krishna C, Prathima NB, Malini R, Vadhiraja BM, Bhat RA, Donald JF, et al. Raman spectroscopy studies for diagnosis of cancers in human uterine cervix. Vib Spectrosc 2006;41:136-41.
92. Parker ES. Applications of infrared and Raman and resonance Raman spectroscopy in biochemistry. Plenum Press: New York; 1983.
93. Tonge PJ, Carey PR, Raman, resonance raman and FTIR spectroscopic studies of enzyme-substrate complexes. In: Clark RJ, Hester RE, editors. Biomolecular Spectroscopy Part A, Advances in Spectroscopy, Vol 20, John Wiley and Sons: Chchester; p. 129 (Chapter 3).
94. Mahalanobis JC. On generalized distance in statistics. Proc Natl Inst Sci India 1936;2:49-55.
95. Mark HL. Use of mahalanobis distances to evaluate sample preparation methods for near-infrared reflectance analysis. Anal Chem 1987;59:790-5.
96. PLSplus/IQ User's Guide. Galactic Industries Corporation.
97. Malini R, Venkatakrishna K, Kurien J, Pai KM, Lakshmi Rao, Kartha VB, et al. Discrimination of normal, inflammatory, premalignant and malignant oral tissue: A Raman spectroscopy study. Biopolymers 2006;81:179-93.
98. Chowdary MV, Kalyan KK, Kurien J, Mathew S, Murali Krishna C. Discrimination of normal, benign and malignant breast tissue by Raman Spectroscopy. Biopolymers 2006;83:556-69.
99. Kalyan KK, Anand A, Chowdary MV, Keerthi, Kurien J, Murali Krishna C, et al. Discrimination of normal and malignant stomach mucosal tissues by Raman spectroscopy: A pilot study. Vib Spectrosc 2007;44:382-7.
100. Chowdary MV, Kalyan KK, Keerthi, Anand A, Kurien J, Murali Krishna C, et al. Discrimination of normal and malignant mucosal tissue of colon by Raman spectroscopy. Photomed Laser Surg 2007;25:269-74.
101. Vidyasagar MS, Maheedhar K, Vadiraja BM, Donald JF, Kartha VB, Murali Krishna C. Prediction of radiotherapy response in cervix cancer by Raman spectroscopy: A pilot study. Biopolymers 2008, In Press.
102. Vidyasagar MS, Maheedhar K, Vadiraja BM, Donald JF, Kartha VB, Murali Krishna C. Raman spectroscopy of tissues collected at different fractions of radiation therapy: Response assessment to radiotherapy in cervix cancers. Int J Radiat Oncol Biol Physics 2007;69:S388-9.
103. Murali Krishna C, Sockalingum GD, Vadhiraja BM, Maheedhar K, Anuradha Rao CK, Rao L, et al. Vibrational spectroscopic study of formalin fixed cervix tissues. Biopolymers 2007;85:214-21.