Variant CD44 expression by human fibroblasts

Biomarkers

Volumn 13, Issue 3, 2008, Pages 307-318

  Rajarajan, Abirami ^a   Bloor, Balvinder ^a   Desai, Hemini ^a   Stokes, Angela ^a   Odell, Edward ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

CD44; Constitutive exons; mRNA splicing; Variant exons

Indexed keywords

CD44V ANTIGEN; MESSENGER RNA;

ANTIGEN DETECTION; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; EXON; FIBROBLAST; FIBROBLAST CULTURE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PROTEIN ANALYSIS; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ALTERNATIVE SPLICING; ANTIGENS, CD44; EXONS; FIBROBLASTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; MODELS, BIOLOGICAL; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 42349097659     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.1080/13547500701800056     Document Type: Article

References (42)

1. Arch, R., Wirth, K., Hofmann, M., Ponta, H., Matzku, S., Herrlich, P. and Zoller, M. (1992) Participation in normal immune responses of a metastasis-inducing splice variant of CD44. Science, 257, pp. 682-685.
2. Arlett, CF, Green, MH, Priestley, A., Harcourt, SA and Mayne, LV (1988) Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. International Journal of Radiation Biology, 54, pp. 911-928.
3. Bloor, BK, Jelvagharan, M., White, KN and Odell, EW (2001) Characterization of CD44 splicing patterns in normal keratinocytes, dysplastic and squamous carcinoma cell lines. International Journal of Oncology, 18, pp. 1053-1059.
4. Bloor, BK, Rajarajan, A., Jaafary-Haghighat, K. and Odell, EW (2002) Transcription and expression of CD44 variant exons by oro-pharyngeal squamous cell carcinomas. International Journal of Oncology, 21, pp. 907-913.
5. Croft, DR, Dall, P., Davies, D., Jackson, DG, McIntyre, P. and Kramer, IM (1997) Complex CD44 splicing combinations in synovial fibroblasts from arthritic joints. European Journal of Immunology, 27, pp. 1680-1684.
6. Dall, P., Heider, KH, Hekele, A., von Minckwitz, G., Kaufmann, M., Ponta, H. and Herrlich, P. (1994) Surface protein expression and messenger RNA-splicing analysis of CD44 in uterine cervical cancer and normal cervical epithelium. Cancer Research, 54, pp. 3337-3341.
7. Finn, L., Dougherty, G., Finley, G., Meisler, A., Becich, M. and Cooper, DL (1994) Alternative splicing of CD44 pre-mRNA in human colorectal tumors. Biochemical and Biophysical Research Communications, 200, pp. 1015-1022.
8. Foekens, JA, Dall, P., Klijn, JG, Skroch-Angel, P., Claassen, CJ, Look, MP, Ponta, H., Van Putten, WL, Herrlich, P. and Henzen-Logmans, SC (1999) Prognostic value of CD44 variant expression in primary breast cancer. International Journal of Cancer, 84, pp. 209-215.
9. Goodison, S. and Tarin, D. (1998) Current status of CD44 variant isoforms as cancer diagnostic markers. Histopathology, 32, pp. 1-6.
10. Goodison, S., Yoshida, K., Churchman, M. and Tarin, D. (1998) Multiple intron retention occurs in tumor cell CD44 mRNA processing. American Journal of Pathology, 153, pp. 1221-1228.
11. Green, MH, Arlett, CF, Cole, J., Harcourt, SA, Priestley, A., Waugh, AP, Stephens, G., Beare, DM, Brown, NA and Shun-Shin, GA (1991) Comparative human cellular radiosensitivity: III. Gamma-radiation survival of cultured skin fibroblasts and resting T-lymphocytes from the peripheral blood of the same individual. International Journal of Radiation Biology, 59, pp. 749-765.
12. Griffioen, AW, Horst, E., Heider, KH, Wielenga, VJ, Adolf, GR, Herrlich, P. and Pals, ST (1994) Expression of CD44 splice variants during lymphocyte activation and tumor progression. Cell Adhesion Communications, 2, pp. 195-200.
13. Harlow, E. and Lane, DP (1989) Antibodies: A laboratory manual. Cold Spring Harbour, Cold Spring Harbour Laboratory Press, New York
14. Haynes, BF, Liao, HX and Patton, KL (1991) The transmembrane hyaluronate receptor CD44: Multiple functions, multiple forms. Cancer Cells, 3, pp. 347-350.
15. Haynes, BF, Telen, MJ, Hale, LP and Denning, SM (1989) CD44-a molecule involved in leukocyte adherence and T-cell activation. Immunology Today, 10, pp. 423-428.
16. Heider, KH, Hofmann, M., Hors, E., Berg, F Van den, Ponta, H., Herrlich, P. and Pals, ST (1993) A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps. Journal of Cell Biology, 120, pp. 227-233.
17. Herrera-Gayol, A. and Jothy, S. (1999) Adhesion proteins in the biology of breast cancer: Contribution of CD44. Experimental and Molecular Pathology, 66, pp. 149-156.
18. Hirano, F., Hirano, H., Hino, E., Takayama, S., Saito, K., Kusumoto, Y., Shimabukuro, Y., Murakami, S. and Okada, H. (1997) CD44 isoform expression in periodontal tissues: Cell-type specific regulation of alternative splicing. Journal of Periodontal Research, 32, pp. 634-645.
19. Hudson, D. L., Sleeman, J. and Watt, FM (1995) CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion. Journal of Cell Science, 108, pp. 1959-1970.
20. Hudson, DL, Speight, PM and Watt, FM (1996) Altered expression of CD44 isoforms in squamous-cell carcinomas and cell lines derived from them. International Journal of Cancer, 66, pp. 457-463.
21. Li, H., Fan, X. and Houghton, J. (2007) Tumor microenvironment: The role of the tumor stroma in cancer. Journal of Cell Biochemistry, 101, pp. 805-815.
22. Martegani, MP, Del, PF, Gasbarri, A., Natali, PG and Bartolazzi, A. (1999) Structural variability of CD44v molecules and reliability of immunodetection of CD44 isoforms using mAbs specific for CD44 variant exon products. American Journal of Pathology, 154, pp. 291-300.
23. Matsumura, Y., Sugiyama, M., Matsumura, S., Hayle, AJ, Robinson, P., Smith, JC and Tarin, D. (1995) Unusual retention of introns in CD44 gene transcripts in bladder cancer provides new diagnostic and clinical oncological opportunities. Journal of Pathology, 177, pp. 11-20.
24. Matsumura, Y. and Tarin, D. (1992) Significance of CD44 gene products for cancer diagnosis and disease evaluation. Lancet, 340, pp. 1053-1058.
25. Mersmann, M., Schmidt, A., Rippmann, JF, Wuest, T., Brocks, B., Rettig, WJ, Garin-Chesa, P., Pfizenmaier, K. and Moosmayer, D. (2001) Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas. International Journal of Cancer, 92, pp. 240-248.
26. Miyake, H., Eto, H., Arakawa, S., Kamidono, S. and Hara, I. (2002) Over expression of CD44V8-10 in urinary exfoliated cells as an independent prognostic predictor in patients with urothelial cancer. Journal of Urology, 167, pp. 1282-1287.
27. Mueller, MM and Fusenig, NE (2002) Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells. Differentiation, 70, pp. 486-497.
28. Naor, D., Sionov, RV and Ish-Shalom, D. (1997) CD44: Structure, function, and association with the malignant process. Advances in Cancer Research, 71, pp. 241-319.
29. Ni, HM, Leong, AF, Cheong, D. and Hooi, S. (2002) Expression of CD44 variants in colorectal carcinoma quantified by real-time reverse transcriptase-polymerase chain reaction. Journal of Laboratory & Clinical Medicine, 139, pp. 59-65.
30. Patel, V., Jakus, J., Harris, CM, Ensley, JF, Robbins, KC and Yeudall, WA (1997) Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck. International Journal of Cancer, 73, pp. 551-555.
31. Pedersen, TX, Pennington, CJ, Almholt, K., Christensen, IJ, Nielsen, BS, Edwards, DR, Romer, J., Dano, K. and Johnsen, M. (2005) Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas. Carcinogenesis, 26, pp. 1233-1240.
32. Shtivelman, E. and Bishop, JM (1991) Expression of CD44 is repressed in neuroblastoma cells. Molecular & Cell Biology, 11, pp. 5446-5453.
33. Sugino, T., Yoshida, K., Zhao, S., Goodison, S. and Tarin, D. (1998) Disorderly CD44 gene expression in human cancer cells can be modulated by growth conditions. Journal of Pathology, 186, pp. 17-23.
34. Tahtis, K., Lee, FT, Wheatley, JM, Garin-Chesa, P., Park, JE, Smyth, FE, Obata, Y., Stockert, E., Hall, CM, Old, LJ, Rettig, WJ and Scott, AM (2003) Expression and targeting of human fibroblast activation protein in a human skin/severe combined immunodeficient mouse breast cancer xenograft model. Molecular Cancer Therapeutics, 2, pp. 729-737.
35. Tanabe, KK, Ellis, LM and Saya, H. (1993) Expression of CD44R1 adhesion molecule in colon carcinomas and metastases. Lancet, 341, pp. 725-726.
36. Tarin, D. and Matsumura, Y. (1993) Deranged activity of the CD44 gene and other loci as biomarkers for progression to metastatic malignancy. Journal of Cell Biochemistry Supplement, 17, pp. 173-185.
37. Wibulswas, A., Croft, D., Bacarese-Hamilton, I., McIntyre, P., Genot, E. and Kramer, IM (2000) The CD44v7/8 epitope as a target to restrain proliferation of fibroblast-like synoviocytes in rheumatoid arthritis. American Journal of Pathology, 157, pp. 2037-2044.
38. Wibulswas, A., Croft, D., Pitsillides, AA, Bacarese-Hamilton, I., McIntyre, P., Genot, E. and Kramer, IM (2002) Influence of epitopes CD44v3 and CD44v6 in the invasive behavior of fibroblast-like synoviocytes derived from rheumatoid arthritic joints. Arthritis & Rheumatism, 46, pp. 2059-2064.
39. Woodman, AC, Sugiyama, M., Yoshida, K., Sugino, T., Borgya, A., Goodison, S., Matsumura, Y. and Tarin, D. (1996) Analysis of anomalous CD44 gene expression in human breast, bladder, and colon cancer and correlation of observed mRNA and protein isoforms. American Journal of Pathology, 149, pp. 1519-1530.
40. Yoshida, K., Bolodeoku, J., Sugino, T., Goodison, S., Matsumura, Y., Warren, BF, Toge, T., Tahara, E. and Tarin, D. (1995) Abnormal retention of intron 9 in CD44 gene transcripts in human gastrointestinal tumors. Cancer Research, 55, pp. 4273-4277.
41. Zhang, J. and Madden, TL (1997) PowerBLAST: A new network BLAST application for interactive or automated sequence analysis and annotation. Genome Research, 7, pp. 649-656.
42. Zhou, J., Haggerty, JG and Milstone, LM (1999) Growth and differentiation regulate CD44 expression on human keratinocytes. In Vitro Cellular & Developmental Biology. Animal, 35, pp. 228-235.