Over expression of CD44V8-10 in urinary exfoliated cells as an independent prognostic predictor in patients with urothelial cancer

Journal of Urology

Volumn 167, Issue 3, 2002, Pages 1282-1287

  Miyake, Hideaki ^a   Eto, Hiroshi ^a   Arakawa, Soichi ^a   Kamidono, Sadao ^a   Hara, Isao ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Antigens, CD44; Neoplasmas; Tumor markers, biological; Urinary tract; Urothelium

Indexed keywords

CD44V ANTIGEN;

ALTERNATIVE RNA SPLICING; ANTIGEN EXPRESSION; ARTICLE; BLADDER CANCER; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY PELVIS CANCER; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; TUMOR GROWTH; URETER CANCER; URINALYSIS; UROGENITAL TRACT TUMOR;

EID: 0036166084     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)65282-2     Document Type: Article

References (22)

1. Natural history of bladder cancer
2. Molecular detection of primary bladder cancer by microsatellite analysis
3. Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer
4. Independent prognostic value of serum hepatocyte growth factor in bladder cancer
5. Increased angiogenin expression in the tumor tissue and serum in urothelial carcinoma patients is related to disease progression and recurrence
6. Elevation of serum level of vascular endothelial growth factor as a new predictor of recurrence and disease progression in patients with superficial urothelial cancer
7. Interaction between CD44 and hyarulonate is directory implicated in the regulation of tumor development
8. Novel variants of CD44 arising from alternative splicing pattern of MCF-7 breast carcinoma cells treated with hyaluronidase
9. Expression of CD44R1 adhesion molecule in colon carcinomas and metastases
10. Expression of CD44 adhesion molecule in non-papillary renal cell carcinomas and normal kidneys
11. Molecular detection of cancer cells by competitive reverse transcription-polymerase chain reaction analysis of specific CD44 variant RNAs
12. Expression patterns of CD44 adhesion molecule in testicular germ cell tumors and normal testes
13. Highly specific and sensitive detection of malignancy in urine samples from patients with urothelial cancer by CD44v8-10/CD44v10 competitive RT-PCR
14. Urinary cytology and competitive reverse transcriptase-polymerase chain reaction analysis of a specific CD44 variant to detect and monitor bladder cancer
15. Utility of competitive reverse transcription-polymerase chain reaction analysis of specific CD44 variant RNA for detecting upper urinary tract transitional cell carcinoma
16. Single-step method of RNA isolated by acid guanidinium thiocyanate-phenol-chloroform extraction
17. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma
18. Patterns of splice variant CD44 expression by normal human urothelium in situ and in vitro and by bladder-carcinoma cell lines
19. Alternatively spliced variants or the cell adhesion molecule CD44 and tumor progression in colorectal cancer
20. CD44 expression patterns in breast and colon tumors: A PCR-based study of splice variants
21. Progression in gastric carcinoma relative to the ratio of CD44 epithelial variant transcript to CD44 hematopoietic variant transcript
22. Increased expression of CD44 variants in differentiated thyroid cancers