메뉴 건너뛰기




Volumn 15, Issue 3, 2008, Pages 312-320

Effect of relaxin on TGF-β1 expression in cultured vaginal fibroblasts from women with stress urinary incontinence

Author keywords

Extracellular matrix; Fibroblasts; Relaxin; Stress urinary incontinence; TGF 1

Indexed keywords

BINDING PROTEIN; RELAXIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA1 BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 42249088881     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719108315299     Document Type: Article
Times cited : (19)

References (44)
  • 2
    • 6744256899 scopus 로고
    • Pregnancy, childbirth, and the menopause related to the development of stress incontinence
    • Beck RP, Hsu N. Pregnancy, childbirth, and the menopause related to the development of stress incontinence. Am J Obstet Gynecol. 1965 ; 91: 820-823.
    • (1965) Am J Obstet Gynecol , vol.91 , pp. 820-823
    • Beck, R.P.1    Hsu, N.2
  • 3
    • 0034116598 scopus 로고    scopus 로고
    • Racial differences in the structure and function of the stress urinary continence mechanism
    • Howard D., Delancey JO, Tunn R., Ashton-Miller JA Racial differences in the structure and function of the stress urinary continence mechanism. Obstet Gynecol. 2000 ; 95: 713-717.
    • (2000) Obstet Gynecol , vol.95 , pp. 713-717
    • Howard, D.1    Delancey, J.O.2    Tunn, R.3    Ashton-Miller, J.A.4
  • 4
    • 0036900664 scopus 로고    scopus 로고
    • Urinary incontinence predictors and life impact in ethnically diverse perimenopausal women
    • Sampselle CM, Harlow SD, Skurnick J., Brubaker L., Bondarenko I. Urinary incontinence predictors and life impact in ethnically diverse perimenopausal women. Obstet Gynecol. 2002 ; 100: 1230-1238.
    • (2002) Obstet Gynecol , vol.100 , pp. 1230-1238
    • Sampselle, C.M.1    Harlow, S.D.2    Skurnick, J.3    Brubaker, L.4    Bondarenko, I.5
  • 6
    • 0032125861 scopus 로고    scopus 로고
    • Effect of simulated birth trauma on the urinary continence mechanism in the rat
    • Lin AS, Carrier S., Morgan DM, Lue TF Effect of simulated birth trauma on the urinary continence mechanism in the rat. Urology. 1998 ; 52: 143-151.
    • (1998) Urology , vol.52 , pp. 143-151
    • Lin, A.S.1    Carrier, S.2    Morgan, D.M.3    Lue, T.F.4
  • 7
    • 0031046646 scopus 로고    scopus 로고
    • Growth factors in the extracellular matrix
    • Taipale J., Keski-Oja J. Growth factors in the extracellular matrix. FASEB J. 1997 ; 11: 51-59.
    • (1997) FASEB J , vol.11 , pp. 51-59
    • Taipale, J.1    Keski-Oja, J.2
  • 8
    • 0025500761 scopus 로고
    • Transforming growth factor-beta increases elastin production by neonatal rat lung fibroblasts
    • McGowan SE, McNamer R. Transforming growth factor-beta increases elastin production by neonatal rat lung fibroblasts. Am J Respir Cell Mol Biol. 1990 ; 3: 369-376.
    • (1990) Am J Respir Cell Mol Biol , vol.3 , pp. 369-376
    • McGowan, S.E.1    McNamer, R.2
  • 9
    • 0030946194 scopus 로고    scopus 로고
    • TGF-beta latency: Biological significance and mechanisms of activation
    • Gleizes PE, Munger JS, Nunes I., et al. TGF-beta latency: biological significance and mechanisms of activation. Stem Cells. 1997 ; 15: 190-197.
    • (1997) Stem Cells , vol.15 , pp. 190-197
    • Gleizes, P.E.1    Munger, J.S.2    Nunes, I.3
  • 10
    • 0025866180 scopus 로고
    • Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts: Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression
    • Overall CM, Wrana JL, Sodek J. Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts: comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem. 1991 ; 266: 14064-14071.
    • (1991) J Biol Chem , vol.266 , pp. 14064-14071
    • Overall, C.M.1    Wrana, J.L.2    Sodek, J.3
  • 11
    • 0031684855 scopus 로고    scopus 로고
    • Extracellular matrix-associated transforming growth factor-beta: Role in cancer cell growth and invasion
    • Taipale J., Saharinen J., Keski-Oja J. Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion. Adv Cancer Res. 1998 ; 75: 87-134.
    • (1998) Adv Cancer Res , vol.75 , pp. 87-134
    • Taipale, J.1    Saharinen, J.2    Keski-Oja, J.3
  • 12
    • 0033367321 scopus 로고    scopus 로고
    • Regulation and regulatory activities of transforming growth factor beta
    • Bonewald LF Regulation and regulatory activities of transforming growth factor beta. Crit Rev Eukaryot Gene Expr. 1999 ; 9: 33-44.
    • (1999) Crit Rev Eukaryot Gene Expr , vol.9 , pp. 33-44
    • Bonewald, L.F.1
  • 13
    • 0037439630 scopus 로고    scopus 로고
    • Making sense of latent TGFbeta activation
    • Annes JP, Munger JS, Rifkin DB Making sense of latent TGFbeta activation. J Cell Sci. 2003 ; 116: 217-224.
    • (2003) J Cell Sci , vol.116 , pp. 217-224
    • Annes, J.P.1    Munger, J.S.2    Rifkin, D.B.3
  • 15
    • 0031227466 scopus 로고    scopus 로고
    • Decrease in elastin gene expression and protein synthesis in fibroblasts derived from cardinal ligaments of patients with prolapsus uteri
    • Yamamoto K., Yamamoto M., Akazawa K., Tajima S., Wakimoto H., Aoyagi M. Decrease in elastin gene expression and protein synthesis in fibroblasts derived from cardinal ligaments of patients with prolapsus uteri. Cell Biol Int. 1997 ; 21: 605-611.
    • (1997) Cell Biol Int , vol.21 , pp. 605-611
    • Yamamoto, K.1    Yamamoto, M.2    Akazawa, K.3    Tajima, S.4    Wakimoto, H.5    Aoyagi, M.6
  • 16
    • 0036271444 scopus 로고    scopus 로고
    • Collagen metabolism and turnover in women with stress urinary incontinence and pelvic prolapse
    • Chen BH, Wen Y., Li H., Polan ML Collagen metabolism and turnover in women with stress urinary incontinence and pelvic prolapse. Int Urogynecol J Pelvic Floor Dysfunct. 2002 ; 13: 80-87.
    • (2002) Int Urogynecol J Pelvic Floor Dysfunct , vol.13 , pp. 80-87
    • Chen, B.H.1    Wen, Y.2    Li, H.3    Polan, M.L.4
  • 17
    • 1542333614 scopus 로고    scopus 로고
    • Elastolytic activity in women with stress urinary incontinence and pelvic organ prolapse
    • Chen B., Wen Y., Polan ML Elastolytic activity in women with stress urinary incontinence and pelvic organ prolapse. Neurourol Urodyn. 2004 ; 23: 119-126.
    • (2004) Neurourol Urodyn , vol.23 , pp. 119-126
    • Chen, B.1    Wen, Y.2    Polan, M.L.3
  • 18
    • 34247177489 scopus 로고    scopus 로고
    • The role of neutrophil elastase in elastin metabolism of pelvic tissues from women with stress urinary incontinence
    • Chen B., Wen Y., Yu X., Polan ML The role of neutrophil elastase in elastin metabolism of pelvic tissues from women with stress urinary incontinence. Neurourol Urodyn. 2007 ; 26: 274-279.
    • (2007) Neurourol Urodyn , vol.26 , pp. 274-279
    • Chen, B.1    Wen, Y.2    Yu, X.3    Polan, M.L.4
  • 19
    • 34548062188 scopus 로고    scopus 로고
    • Relaxin: Antifibrotic properties and effects in models of disease
    • Samuel CS Relaxin: antifibrotic properties and effects in models of disease. Clin Med Res. 2005 ; 3: 241-249.
    • (2005) Clin Med Res , vol.3 , pp. 241-249
    • Samuel, C.S.1
  • 20
    • 0025302162 scopus 로고
    • Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts
    • Unemori EN, Amento EP Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts. J Biol Chem. 1990 ; 265: 10681-10685.
    • (1990) J Biol Chem , vol.265 , pp. 10681-10685
    • Unemori, E.N.1    Amento, E.P.2
  • 21
    • 0030453783 scopus 로고    scopus 로고
    • Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo
    • Unemori EN, Pickford LB, Salles AL, et al. Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo. J Clin Invest. 1996 ; 98: 2739-2745.
    • (1996) J Clin Invest , vol.98 , pp. 2739-2745
    • Unemori, E.N.1    Pickford, L.B.2    Salles, A.L.3
  • 22
    • 23644458767 scopus 로고    scopus 로고
    • Relaxin modulates fibroblast function, collagen production, and matrix metalloproteinase-2 expression by cardiac fibroblasts
    • Mookerjee I., Unemori EN, Du XJ, Tregear GW, Samuel CS Relaxin modulates fibroblast function, collagen production, and matrix metalloproteinase-2 expression by cardiac fibroblasts. Ann N Y Acad Sci. 2005 ; 1041: 190-193.
    • (2005) Ann N Y Acad Sci , vol.1041 , pp. 190-193
    • Mookerjee, I.1    Unemori, E.N.2    Du, X.J.3    Tregear, G.W.4    Samuel, C.S.5
  • 23
    • 23644461048 scopus 로고    scopus 로고
    • Relaxin regulates collagen overproduction associated with experimental progressive renal fibrosis
    • Samuel CS, Mookerjee I., Masterson R., Tregear GW, Hewitson TD Relaxin regulates collagen overproduction associated with experimental progressive renal fibrosis. Ann N Y Acad Sci. 2005 ; 1041: 182-184.
    • (2005) Ann N Y Acad Sci , vol.1041 , pp. 182-184
    • Samuel, C.S.1    Mookerjee, I.2    Masterson, R.3    Tregear, G.W.4    Hewitson, T.D.5
  • 24
    • 0034612234 scopus 로고    scopus 로고
    • Recombinant human relaxin in the treatment of scleroderma: A randomized, double-blind, placebo-controlled trial
    • Seibold JR, Korn JH, Simms R., et al. Recombinant human relaxin in the treatment of scleroderma: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000 ; 132: 871-879.
    • (2000) Ann Intern Med , vol.132 , pp. 871-879
    • Seibold, J.R.1    Korn, J.H.2    Simms, R.3
  • 25
    • 0034925715 scopus 로고    scopus 로고
    • Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway
    • Palejwala S., Stein DE, Weiss G., Monia BP, Tortoriello D., Goldsmith LT Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway. Endocrinology. 2001 ; 142: 3405-3413.
    • (2001) Endocrinology , vol.142 , pp. 3405-3413
    • Palejwala, S.1    De, S.2    Weiss, G.3    Monia, B.P.4    Tortoriello, D.5    Goldsmith, L.T.6
  • 26
    • 20644440838 scopus 로고    scopus 로고
    • Elastin metabolism in pelvic tissues: Is it modulated by reproductive hormones
    • Chen B., Wen Y., Yu X., Polan ML Elastin metabolism in pelvic tissues: is it modulated by reproductive hormones ? Am J Obstet Gynecol. 2005 ; 192: 1605-1613.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 1605-1613
    • Chen, B.1    Wen, Y.2    Yu, X.3    Polan, M.L.4
  • 27
    • 0033305426 scopus 로고    scopus 로고
    • Potential mechanisms for the plasmin-mediated release and activation of latent transforming growth factor-beta1 from the extracellular matrix of growth plate chondrocytes
    • Pedrozo HA, Schwartz Z., Robinson M., et al. Potential mechanisms for the plasmin-mediated release and activation of latent transforming growth factor-beta1 from the extracellular matrix of growth plate chondrocytes. Endocrinology. 1999 ; 140: 5806-5816.
    • (1999) Endocrinology , vol.140 , pp. 5806-5816
    • Pedrozo, H.A.1    Schwartz, Z.2    Robinson, M.3
  • 28
    • 0026447801 scopus 로고
    • Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin
    • Taipale J., Koli K., Keski-Oja J. Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin. J Biol Chem. 1992 ; 267: 25378-25384.
    • (1992) J Biol Chem , vol.267 , pp. 25378-25384
    • Taipale, J.1    Koli, K.2    Keski-Oja, J.3
  • 29
    • 0027976521 scopus 로고
    • Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein
    • Taipale J., Miyazono K., Heldin CH, Keski-Oja J. Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein. J Cell Biol. 1994 ; 124: 171-181.
    • (1994) J Cell Biol , vol.124 , pp. 171-181
    • Taipale, J.1    Miyazono, K.2    Ch, H.3    Keski-Oja, J.4
  • 30
  • 31
    • 0031021409 scopus 로고    scopus 로고
    • Relaxin: A pleiotropic hormone
    • Bani D. Relaxin: a pleiotropic hormone. Gen Pharmacol. 1997 ; 28: 13-22.
    • (1997) Gen Pharmacol , vol.28 , pp. 13-22
    • Bani, D.1
  • 32
    • 0035096195 scopus 로고    scopus 로고
    • Relaxin decreases renal interstitial fibrosis and slows progression of renal disease
    • Garber SL, Mirochnik Y., Brecklin CS, et al. Relaxin decreases renal interstitial fibrosis and slows progression of renal disease. Kidney Int. 2001 ; 59: 876-882.
    • (2001) Kidney Int , vol.59 , pp. 876-882
    • Garber, S.L.1    Mirochnik, Y.2    Brecklin, C.S.3
  • 33
    • 24944542890 scopus 로고    scopus 로고
    • The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway
    • Heeg MHJ, Koziolek MJ, Vasko R., et al. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway. Kidney Int. 2005 ; 68: 96-109.
    • (2005) Kidney Int , vol.68 , pp. 96-109
    • Mhj, H.1    Koziolek, M.J.2    Vasko, R.3
  • 34
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • Border WA, Noble NA Transforming growth factor beta in tissue fibrosis. N Engl J Med. 1994 ; 331: 1286-1292.
    • (1994) N Engl J Med , vol.331 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 35
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • Blobe GC, Schiemann WP, Lodish HF Role of transforming growth factor beta in human disease. N Engl J Med. 2000 ; 342: 1350-1358.
    • (2000) N Engl J Med , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 36
    • 0024382711 scopus 로고
    • Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture
    • Sato Y., Rifkin DB Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture. J Cell Biol. 1989 ; 109: 309-315.
    • (1989) J Cell Biol , vol.109 , pp. 309-315
    • Sato, Y.1    Rifkin, D.B.2
  • 37
    • 0034650486 scopus 로고    scopus 로고
    • Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
    • Yu Q., Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev. 2000 ; 14: 163-176.
    • (2000) Genes Dev , vol.14 , pp. 163-176
    • Yu, Q.1    Stamenkovic, I.2
  • 38
    • 0028885716 scopus 로고
    • Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein
    • Dallas SL, Miyazono K., Skerry TM, Mundy GR, Bonewald LF Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein. J Cell Biol. 1995 ; 131: 539-549.
    • (1995) J Cell Biol , vol.131 , pp. 539-549
    • Dallas, S.L.1    Miyazono, K.2    Skerry, T.M.3    Mundy, G.R.4    Bonewald, L.F.5
  • 39
    • 0028956737 scopus 로고
    • Human mast cell chymase and leukocyte elastase release latent transforming growth factor-beta 1 from the extracellular matrix of cultured human epithelial and endothelial cells
    • Taipale J., Lohi J., Saarinen J., Kovanen PT, Keski-Oja J. Human mast cell chymase and leukocyte elastase release latent transforming growth factor-beta 1 from the extracellular matrix of cultured human epithelial and endothelial cells. J Biol Chem. 1995 ; 270: 4689-4696.
    • (1995) J Biol Chem , vol.270 , pp. 4689-4696
    • Taipale, J.1    Lohi, J.2    Saarinen, J.3    Kovanen, P.T.4    Keski-Oja, J.5
  • 40
    • 0037077212 scopus 로고    scopus 로고
    • Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts: A cellular mechanism for release of TGF-beta from bone matrix
    • Dallas SL, Rosser JL, Mundy GR, Bonewald LF Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts: a cellular mechanism for release of TGF-beta from bone matrix. JBiol Chem. 2002 ; 277: 21352-21360.
    • (2002) JBiol Chem , vol.277 , pp. 21352-21360
    • Dallas, S.L.1    Rosser, J.L.2    Mundy, G.R.3    Bonewald, L.F.4
  • 41
    • 0030715322 scopus 로고    scopus 로고
    • ECM and cell surface proteolysis: Regulating cellular ecology
    • Werb Z. ECM and cell surface proteolysis: regulating cellular ecology. Cell. 1997 ; 91: 439-442.
    • (1997) Cell , vol.91 , pp. 439-442
    • Werb, Z.1
  • 42
    • 0032030785 scopus 로고    scopus 로고
    • Cleavage of native type I collagen by human neutrophil elastase
    • Kafienah W., Buttle DJ, Burnett D., Hollander AP Cleavage of native type I collagen by human neutrophil elastase. Biochem J. 1998 ; 330 (pt 2). 897-902.
    • (1998) Biochem J , vol.330 , Issue.2 , pp. 897-902
    • Kafienah, W.1    Buttle, D.J.2    Burnett, D.3    Hollander, A.P.4
  • 43
    • 0023916551 scopus 로고
    • Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium
    • Lyons RM, Keski-Oja J., Moses HL Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J Cell Biol. 1988 ; 106: 1659-1665.
    • (1988) J Cell Biol , vol.106 , pp. 1659-1665
    • Lyons, R.M.1    Keski-Oja, J.2    Moses, H.L.3
  • 44
    • 36048988128 scopus 로고    scopus 로고
    • 17 β-estradiol attenuates diabetic kidney disease via regulating extracellular matrix and transforming growth factor-beta protein expression and signaling
    • Dixon A., Maric C. 17 β-estradiol attenuates diabetic kidney disease via regulating extracellular matrix and transforming growth factor-beta protein expression and signaling. Am J Physiol Renal Physiol. 2007 ; 293: F1678-1690.
    • (2007) Am J Physiol Renal Physiol , vol.293 , pp. 1678-1690
    • Dixon, A.1    Maric, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.