Relaxin modulates fibroblast function, collagen production, and matrix metalloproteinase-2 expression by cardiac fibroblasts

Annals of the New York Academy of Sciences

Volumn 1041, Issue , 2005, Pages 190-193

  Mookerjee, Ishanee ^a   Unemori, Elaine N ^b   Du, Xiao Jun ^c   Tregear, Geoffrey W ^a   Samuel, Chrishan S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b BAS Medical Inc   (United States)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Cardiac fibroblasts; Collagen; Fibrosis; Matrix metalloproteinases; Relaxin

Indexed keywords

ANGIOTENSIN; COLLAGEN; G PROTEIN COUPLED RECEPTOR; GELATINASE A; GELATINASE B; RECOMBINANT HUMAN RELAXIN 2; RELAXIN; RELAXIN RECEPTOR; RELAXIN RECEPTOR LGR7; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; CELL DIFFERENTIATION; COLLAGEN SYNTHESIS; CONFERENCE PAPER; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; NEWBORN; NONHUMAN; RAT;

EID: 23644458767     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1282.028     Document Type: Conference Paper

References (5)

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3. DU, X.-J., C.S. SAMUEL, X.-M. GAO, et al. 2003. Increased myocardial collagen and ventricular diastolic dysfunction in relaxin-deficient mice: a gender-specific phenotype. Cardiovasc. Res. 57: 395-404.
4. SAMUEL, C.S., E.N. UNEMORI, I. MOOKERJEE, et al. 2004. Relaxin modulates cardiac fibroblast proliferation, differentiation and collagen production and reverses cardiac fibrosis in vivo. Endocrinology 145: 4125-4133.
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