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This detailed position paper by the American Academy of Pediatrics provides a useful overview of the basis for current recommendations on dietary allergy prevention
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Greer FR, Sicherer SH, Burks AW. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics 2008; 121:183-191. This detailed position paper by the American Academy of Pediatrics provides a useful overview of the basis for current recommendations on dietary allergy prevention.
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This 2-year follow-up of the Dutch KOALA study shows that the risk of eczema and wheeze in relation to breast-feeding is modified by maternal allergy risk
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33845951414
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Kukkonen K, Savilahti E, Haahtela T, et al. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2007; 119:192-198. The combined supplementation of mother and infant with prebiotics and probiotics was not effective in preventing eczema at 2 years of age.
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Kukkonen K, Savilahti E, Haahtela T, et al. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2007; 119:192-198. The combined supplementation of mother and infant with prebiotics and probiotics was not effective in preventing eczema at 2 years of age.
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50
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34547102757
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Probiotics for the prevention or treatment of allergic diseases
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This paper provides a detailed systematic review of probiotics in the prevention of allergic diseases
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Prescott SL, Björkstén B. Probiotics for the prevention or treatment of allergic diseases. J Allergy Clin Immunol 2007; 120:255-262. This paper provides a detailed systematic review of probiotics in the prevention of allergic diseases.
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(2007)
J Allergy Clin Immunol
, vol.120
, pp. 255-262
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Prescott, S.L.1
Björkstén, B.2
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51
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34047116237
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Probiotics during the first 7 years of life: A cumulative risk reduction of eczema in a randomized, placebo-controlled trial
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This is the 7-year follow-up of the pioneering study demonstrating sustained reduction in eczema after supplementation of mother and infant during late pregnancy and lactation with LGG
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Kalliomäki M, Salminen S, Poussa T, Isolauri E. Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial. J Allergy Clin Immunol 2007; 119:1019-1021. This is the 7-year follow-up of the pioneering study demonstrating sustained reduction in eczema after supplementation of mother and infant during late pregnancy and lactation with LGG.
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(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1019-1021
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Kalliomäki, M.1
Salminen, S.2
Poussa, T.3
Isolauri, E.4
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52
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34548671863
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IgE food sensitization in infants with eczema attending a dermatology department
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Hill DJ, Heine RG, Hosking CS, et al. IgE food sensitization in infants with eczema attending a dermatology department. J Pediatr 2007; 151:359-363.
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(2007)
J Pediatr
, vol.151
, pp. 359-363
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Hill, D.J.1
Heine, R.G.2
Hosking, C.S.3
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54
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34047124665
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Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization
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This animal study used a novel bioengineered, IL-10 producing Lactococcus lactis strain and demonstrated a reduction in IgE-sensitization to β-lactoglobulin in treated mice
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Frossard CP, Steidler L, Eigenmann PA. Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization. J Allergy Clin Immunol 2007; 119:952-959. This animal study used a novel bioengineered, IL-10 producing Lactococcus lactis strain and demonstrated a reduction in IgE-sensitization to β-lactoglobulin in treated mice.
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(2007)
J Allergy Clin Immunol
, vol.119
, pp. 952-959
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Frossard, C.P.1
Steidler, L.2
Eigenmann, P.A.3
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55
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38449100803
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Osborn DA, Sinn JK. Probiotics in infants for prevention of allergic disease and food hypersensitivity. Cochrane Database Syst Rev 2007; CD006475. This Cochrane review summarizes the complex field of probiotic interventions for atopy prevention and concludes that current data are insufficient to recommend probiotics for allergy prevention. Further studies are recommended.
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Osborn DA, Sinn JK. Probiotics in infants for prevention of allergic disease and food hypersensitivity. Cochrane Database Syst Rev 2007; CD006475. This Cochrane review summarizes the complex field of probiotic interventions for atopy prevention and concludes that current data are insufficient to recommend probiotics for allergy prevention. Further studies are recommended.
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56
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18444399939
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Quantitative real-time PCR assays to identify and quantify fecal Bifidobacterium species in infants receiving a prebiotic infant formula
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Haarman M, Knol J. Quantitative real-time PCR assays to identify and quantify fecal Bifidobacterium species in infants receiving a prebiotic infant formula. Appl Environ Microbiol 2005; 71:2318-2324.
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(2005)
Appl Environ Microbiol
, vol.71
, pp. 2318-2324
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Haarman, M.1
Knol, J.2
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57
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33744495331
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Bifidogenic effects of solid weaning foods with added prebiotic oligosaccharides: A randomised controlled clinical trial
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Scholtens PA, Alles MS, Bindels JG, et al. Bifidogenic effects of solid weaning foods with added prebiotic oligosaccharides: a randomised controlled clinical trial. J Pediatr Gastroenterol Nutr 2006; 42:553-559.
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(2006)
J Pediatr Gastroenterol Nutr
, vol.42
, pp. 553-559
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Scholtens, P.A.1
Alles, M.S.2
Bindels, J.G.3
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58
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0036238964
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Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants
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Moro G, Minoli I, Mosca M, et al. Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants. J Pediatr Gastroenterol Nutr 2002; 34:291-295.
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(2002)
J Pediatr Gastroenterol Nutr
, vol.34
, pp. 291-295
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Moro, G.1
Minoli, I.2
Mosca, M.3
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59
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33749456638
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A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age
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Moro G, Arslanoglu S, Stahl B, et al. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child 2006; 91:814-819.
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(2006)
Arch Dis Child
, vol.91
, pp. 814-819
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Moro, G.1
Arslanoglu, S.2
Stahl, B.3
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60
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44449099320
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Osborn DA, Sinn JK. Prebiotics in infants for prevention of allergic disease and food hypersensitivity. Cochrane Database Syst Rev 2007; CD006474. Although this Cochrane review found some preliminary evidence for an immune modulating effect of prebiotic oligosaccharides, the quality of studies did not allow firm conclusions with regard to allergy prevention, and further research was recommended.
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Osborn DA, Sinn JK. Prebiotics in infants for prevention of allergic disease and food hypersensitivity. Cochrane Database Syst Rev 2007; CD006474. Although this Cochrane review found some preliminary evidence for an immune modulating effect of prebiotic oligosaccharides, the quality of studies did not allow firm conclusions with regard to allergy prevention, and further research was recommended.
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61
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35348868041
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Prenatal fatty acid status and immune development: The pathways and the evidence
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Prescott SL, Dunstan JA. Prenatal fatty acid status and immune development: the pathways and the evidence. Lipids 2007; 42:801-810.
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(2007)
Lipids
, vol.42
, pp. 801-810
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Prescott, S.L.1
Dunstan, J.A.2
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62
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36348937314
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Dunstan JA, Mitoulas LR, Dixon G, et al. The effects of fish oil supplementation in pregnancy on breast milk fatty acid composition over the course of lactation: a randomized controlled trial. Pediatr Res 2007; 62:689-694. This study demonstrates that maternal fish oil supplementation during pregnancy increases DHA levels in breast milk during early lactation, and in the serum of infants at 1 year of age.
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Dunstan JA, Mitoulas LR, Dixon G, et al. The effects of fish oil supplementation in pregnancy on breast milk fatty acid composition over the course of lactation: a randomized controlled trial. Pediatr Res 2007; 62:689-694. This study demonstrates that maternal fish oil supplementation during pregnancy increases DHA levels in breast milk during early lactation, and in the serum of infants at 1 year of age.
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63
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38949117068
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Krauss-Etschmann S, Hartl D, Rzehak P, et al. Decreased cord blood IL-4, IL-13, and CCR4 and increased TGF-beta levels after fish oil supplementation of pregnant women. J Allergy Clin Immunol 2008; 121:464-470. This well designed study showed a decrease in Th-2 cytokines and increase in tolerogenic TGF-β in cord blood after maternal supplementation with EPA/DHA during pregnancy. The clinical significance of this finding in terms of allergy prevention is unknown, and long-term follow-up data are needed.
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Krauss-Etschmann S, Hartl D, Rzehak P, et al. Decreased cord blood IL-4, IL-13, and CCR4 and increased TGF-beta levels after fish oil supplementation of pregnant women. J Allergy Clin Immunol 2008; 121:464-470. This well designed study showed a decrease in Th-2 cytokines and increase in tolerogenic TGF-β in cord blood after maternal supplementation with EPA/DHA during pregnancy. The clinical significance of this finding in terms of allergy prevention is unknown, and long-term follow-up data are needed.
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64
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34047230490
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Maternal fish intake during pregnancy and atopy and asthma in infancy
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Romieu I, Torrent M, Garcia-Esteban R, et al. Maternal fish intake during pregnancy and atopy and asthma in infancy. Clin Exp Allergy 2007; 37:518-525.
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(2007)
Clin Exp Allergy
, vol.37
, pp. 518-525
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Romieu, I.1
Torrent, M.2
Garcia-Esteban, R.3
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65
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34249775193
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Omega-3 and omega-6 fatty acid exposure from early life does not affect atopy and asthma at age 5 years
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This longitudinal study found no evidence of a preventive effect of omega-3 or omega-6 fatty acids for eczema, asthma or atopy. Although maternal omega-3 LCPUFA supplementation during pregnancy may be protective, postnatal supplementation of the infant appears to be ineffective
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Almqvist C, Garden F, Xuan W, et al. Omega-3 and omega-6 fatty acid exposure from early life does not affect atopy and asthma at age 5 years. J Allergy Clin Immunol 2007; 119:1438-1444. This longitudinal study found no evidence of a preventive effect of omega-3 or omega-6 fatty acids for eczema, asthma or atopy. Although maternal omega-3 LCPUFA supplementation during pregnancy may be protective, postnatal supplementation of the infant appears to be ineffective.
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(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1438-1444
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Almqvist, C.1
Garden, F.2
Xuan, W.3
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66
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34948907895
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Role of vitamin A elimination or supplementation diets during postnatal development on the allergic sensitisation in mice
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Rühl R, Hänel A, García AL, et al. Role of vitamin A elimination or supplementation diets during postnatal development on the allergic sensitisation in mice. Mol Nutr Food Res 2007; 51:1173-1181.
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(2007)
Mol Nutr Food Res
, vol.51
, pp. 1173-1181
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Rühl, R.1
Hänel, A.2
García, A.L.3
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67
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34547642619
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Protective effect of fruits, vegetables and the Mediterranean diet on asthma and allergies among children in Crete
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Chatzi L, Apostolaki G, Bibakis I, et al. Protective effect of fruits, vegetables and the Mediterranean diet on asthma and allergies among children in Crete. Thorax 2007; 62:677-683.
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(2007)
Thorax
, vol.62
, pp. 677-683
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Chatzi, L.1
Apostolaki, G.2
Bibakis, I.3
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68
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33846420598
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Supplementation with vitamins C, E, beta-carotene and selenium has no effect on antioxidant status and immune responses in allergic adults: A randomized controlled trial
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Dunstan JA, Breckler L, Hale J, et al. Supplementation with vitamins C, E, beta-carotene and selenium has no effect on antioxidant status and immune responses in allergic adults: a randomized controlled trial. Clin Exp Allergy 2007; 37:180-187.
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(2007)
Clin Exp Allergy
, vol.37
, pp. 180-187
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Dunstan, J.A.1
Breckler, L.2
Hale, J.3
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69
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33749433723
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The vitamin D slant on allergy
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Wjst M. The vitamin D slant on allergy. Pediatr Allergy Immunol 2006; 17:477-483.
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(2006)
Pediatr Allergy Immunol
, vol.17
, pp. 477-483
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Wjst, M.1
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