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Volumn 10, Issue 1, 2008, Pages 7-15

Epilepsy research: A window onto function and dysfunction of the human brain

Author keywords

Epilepsy model; Epilepsy research; Human genetics; Pharmacogenomics; Pharmacoresistance; Transgenic mouse

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE;

EID: 42149161105     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (34)
  • 1
    • 0032536030 scopus 로고    scopus 로고
    • A potassium channel mutation in neonatal human epilepsy
    • Biervert C Schroeder BC, Kubisch C, et al. A potassium channel mutation in neonatal human epilepsy. Science. 1998;279:403-405.
    • (1998) Science , vol.279 , pp. 403-405
    • Biervert, C.1    Schroeder, B.C.2    Kubisch, C.3
  • 2
    • 0036371831 scopus 로고    scopus 로고
    • Channelopathies can cause epilepsy in man
    • Steinlein OK. Channelopathies can cause epilepsy in man. Eur J Pain. 2002;6(suppl A):27-34.
    • (2002) Eur J Pain , vol.6 , Issue.SUPPL. A , pp. 27-34
    • Steinlein, O.K.1
  • 3
    • 34447106560 scopus 로고    scopus 로고
    • Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy
    • Klaassen A, Glykys J, MaGuire, Labarca C, Mody I, Boulter J. Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy. Proc Natl Acad Sci U S A. 2006;103:19152-19157.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19152-19157
    • Klaassen, A.1    Glykys, J.2    MaGuire3    Labarca, C.4    Mody, I.5    Boulter, J.6
  • 4
    • 0027442075 scopus 로고
    • Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model
    • Mathern GW, Cifuentes F, Leite JP, Pretorius JK, Babb TL. Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model. Electroencephalogr Clin Neurophysiol. 1993;87:326-339.
    • (1993) Electroencephalogr Clin Neurophysiol , vol.87 , pp. 326-339
    • Mathern, G.W.1    Cifuentes, F.2    Leite, J.P.3    Pretorius, J.K.4    Babb, T.L.5
  • 5
    • 0025649042 scopus 로고
    • Spontaneous recurrent seizures in rats: An experimental model of partial epilepsy
    • Leite JP, Bortolotto ZA, Cavalheiro EA. Spontaneous recurrent seizures in rats: An experimental model of partial epilepsy. Neurosci Biobehav Rev. 1990;14:511-517.
    • (1990) Neurosci Biobehav Rev , vol.14 , pp. 511-517
    • Leite, J.P.1    Bortolotto, Z.A.2    Cavalheiro, E.A.3
  • 6
    • 0032803304 scopus 로고    scopus 로고
    • Status epilepticus-induced neuronal injury and network reorganization
    • Sloviter RS. Status epilepticus-induced neuronal injury and network reorganization. Epilepsia. 1999;40(suppl 1):S34-S39.
    • (1999) Epilepsia , vol.40 , Issue.SUPPL. 1
    • Sloviter, R.S.1
  • 7
    • 0344172752 scopus 로고    scopus 로고
    • Molecular neuropathology of human mesial temporal lobe epilepsy
    • Blumcke I, Beck H, Lie AA, Wiestler OD. Molecular neuropathology of human mesial temporal lobe epilepsy. Epilepsy Res. 1999;36:205-223.
    • (1999) Epilepsy Res , vol.36 , pp. 205-223
    • Blumcke, I.1    Beck, H.2    Lie, A.A.3    Wiestler, O.D.4
  • 8
    • 0001855752 scopus 로고
    • Pathological findings in epilepsy
    • Engel J, Jr, ed, New York, NY: Raven Press;
    • Babb TL, Brown WJ. Pathological findings in epilepsy. In: Engel J, Jr, ed. Surgical Treatment of the Epilepsies. New York, NY: Raven Press; 1987:511-540.
    • (1987) Surgical Treatment of the Epilepsies , pp. 511-540
    • Babb, T.L.1    Brown, W.J.2
  • 9
    • 0013950709 scopus 로고
    • A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes
    • Margerison JH Corsellis JAN. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain. 1966.89:499-530.
    • (1966) Brain , vol.89 , pp. 499-530
    • Margerison, J.H.1    Corsellis, J.A.N.2
  • 10
    • 0345382778 scopus 로고    scopus 로고
    • A novel mechanism underlying drug-resistance in chronic epilepsy
    • Remy S, Gabriel S, Urban BW, et al. A novel mechanism underlying drug-resistance in chronic epilepsy. Ann Neurol. 2003;53:469-479.
    • (2003) Ann Neurol , vol.53 , pp. 469-479
    • Remy, S.1    Gabriel, S.2    Urban, B.W.3
  • 11
    • 0000229649 scopus 로고
    • Basic research in the setting of an epilepsy surgery center In: Engel J
    • Jr, ed, New York, NY: Raven Press;
    • Schwartzkroin PA. Basic research in the setting of an epilepsy surgery center In: Engel J, Jr, ed. Surgical Treatment of the Epilepsies. New York, NY: Raven Press; 1987:755-770.
    • (1987) Surgical Treatment of the Epilepsies , pp. 755-770
    • Schwartzkroin, P.A.1
  • 12
    • 33645050910 scopus 로고    scopus 로고
    • Epileptiform activity preferentially arises outside tumor invasion zone in glioma xenotransplants
    • Kohling R, Senner V, Paulus W, Speckmann EJ. Epileptiform activity preferentially arises outside tumor invasion zone in glioma xenotransplants. Neurobiol Dis. 2006;22:64-75.
    • (2006) Neurobiol Dis , vol.22 , pp. 64-75
    • Kohling, R.1    Senner, V.2    Paulus, W.3    Speckmann, E.J.4
  • 14
    • 33644893386 scopus 로고    scopus 로고
    • Animal models of post-traumatic epilepsy
    • Pitkanen A, McIntosh TK. Animal models of post-traumatic epilepsy. J Neurotrauma. 2006;23:241-261.
    • (2006) J Neurotrauma , vol.23 , pp. 241-261
    • Pitkanen, A.1    McIntosh, T.K.2
  • 15
    • 4544312032 scopus 로고    scopus 로고
    • Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex
    • Seiffert E, Dreier JP, Ivens S, et al. Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. J Neurosci. 2004;24:7829-7836.
    • (2004) J Neurosci , vol.24 , pp. 7829-7836
    • Seiffert, E.1    Dreier, J.P.2    Ivens, S.3
  • 16
    • 33846291444 scopus 로고    scopus 로고
    • Blood-brain barrier disruption results in delayed functional and structural alterations in the rat neocortex
    • Tomkins O, Friedman O, Ivens S, et al. Blood-brain barrier disruption results in delayed functional and structural alterations in the rat neocortex. Neurobiol Dis. 2007;25:367-377.
    • (2007) Neurobiol Dis , vol.25 , pp. 367-377
    • Tomkins, O.1    Friedman, O.2    Ivens, S.3
  • 17
    • 0036202801 scopus 로고    scopus 로고
    • Epileptic neurons' in temporal lobe epilepsy
    • Yaari Y, Beck H. 'Epileptic neurons' in temporal lobe epilepsy. Brain Pathol. 2002;12:234-239.
    • (2002) Brain Pathol , vol.12 , pp. 234-239
    • Yaari, Y.1    Beck, H.2
  • 18
    • 0033135867 scopus 로고    scopus 로고
    • Altered mitochondrial oxidative phosphorylation in hippocampal slices of kainate-treated rats
    • Kunz WS, Goussakov IV, Beck H, Elger CE. Altered mitochondrial oxidative phosphorylation in hippocampal slices of kainate-treated rats. Brain Res. 1999;826:236-242.
    • (1999) Brain Res , vol.826 , pp. 236-242
    • Kunz, W.S.1    Goussakov, I.V.2    Beck, H.3    Elger, C.E.4
  • 19
    • 0033757831 scopus 로고    scopus 로고
    • Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy
    • Kunz WS, Kudin AP, Vielhaber S, et al. Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy. Ann Neurol. 2000;48:766-773.
    • (2000) Ann Neurol , vol.48 , pp. 766-773
    • Kunz, W.S.1    Kudin, A.P.2    Vielhaber, S.3
  • 20
    • 0027954609 scopus 로고
    • Mitochondrial DNA mutations in epilepsy and neurological disease
    • Wallace DC, Lott MT, Shoffner JM, Ballinger S. Mitochondrial DNA mutations in epilepsy and neurological disease. Epilepsia. 1994;35(suppl 1:S43-S50.
    • (1994) Epilepsia , vol.35 , Issue.SUPPL. 1
    • Wallace, D.C.1    Lott, M.T.2    Shoffner, J.M.3    Ballinger, S.4
  • 21
    • 0036198111 scopus 로고    scopus 로고
    • Destruction of neurons by cytotoxic T cells: A new pathogenic mechanism in Rasmussen's encephalitis
    • Bien CG, Bauer J, Deckworth TL, et al. Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis. Ann Neurol. 2002;51:311-318.
    • (2002) Ann Neurol , vol.51 , pp. 311-318
    • Bien, C.G.1    Bauer, J.2    Deckworth, T.L.3
  • 22
    • 34548725094 scopus 로고    scopus 로고
    • Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy
    • Bien CG, Elger CE, Hans VH, et al. Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy. Neurology. 2007;69:1236-1244.
    • (2007) Neurology , vol.69 , pp. 1236-1244
    • Bien, C.G.1    Elger, C.E.2    Hans, V.H.3
  • 23
    • 34248683271 scopus 로고    scopus 로고
    • Limbic encephalitis: A cause of temporal lobe epilepsy with onset in adult life
    • Bien CG, Elger CE. Limbic encephalitis: a cause of temporal lobe epilepsy with onset in adult life. Epilepsy Behav. 2007;10:529-538.
    • (2007) Epilepsy Behav , vol.10 , pp. 529-538
    • Bien, C.G.1    Elger, C.E.2
  • 24
    • 0001245854 scopus 로고    scopus 로고
    • Intractable epilepsy
    • Engel J, Pedley TA, eds, Philadelphia, Pa: Lippincott-Raven;;
    • Aicardi J, Shorvon SD. Intractable epilepsy. In: Engel J, Pedley TA, eds. Epilepsy: a Comprehensive Textbook. Philadelphia, Pa: Lippincott-Raven;1997;1325-1331.
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 1325-1331
    • Aicardi, J.1    Shorvon, S.D.2
  • 25
    • 0032918385 scopus 로고    scopus 로고
    • Clinical aspects and biological bases of drug-resistant epilepsies
    • Regesta G, Tanganelli P. Clinical aspects and biological bases of drug-resistant epilepsies. Epilepsy Res. 34:1999;109-122.
    • (1999) Epilepsy Res , vol.34 , pp. 109-122
    • Regesta, G.1    Tanganelli, P.2
  • 26
    • 33644807970 scopus 로고    scopus 로고
    • Genetics of drug resistance
    • Sisodiya SM. Genetics of drug resistance. Epilepsia. 2005;46(suppl 10):33-38.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 10 , pp. 33-38
    • Sisodiya, S.M.1
  • 27
    • 30344467212 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of pharmacoresistance in epilepsy
    • Remy S Beck H. Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain. 2006;129:18-35.
    • (2006) Brain , vol.129 , pp. 18-35
    • Remy, S.1    Beck, H.2
  • 28
    • 34249694599 scopus 로고    scopus 로고
    • Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants
    • Li T, Steinbeck JA, Lusardi T, et al. Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants. Brain. 2007;130:1276-1288.
    • (2007) Brain , vol.130 , pp. 1276-1288
    • Li, T.1    Steinbeck, J.A.2    Lusardi, T.3
  • 30
    • 0025118611 scopus 로고
    • Neuronal activity in the human medial temporal lobe during recognition memory
    • Heit G, Smith ME, Halgren E. Neuronal activity in the human medial temporal lobe during recognition memory. Brain. 1990;113:1093-1112.
    • (1990) Brain , vol.113 , pp. 1093-1112
    • Heit, G.1    Smith, M.E.2    Halgren, E.3
  • 31
    • 0027711638 scopus 로고
    • Experimental phenomena evoked by human brain electrical stimulation
    • Halgren E Chauvel P. Experimental phenomena evoked by human brain electrical stimulation. Adv Neurol. 1993;63:123-140.
    • (1993) Adv Neurol , vol.63 , pp. 123-140
    • Halgren, E.1    Chauvel, P.2
  • 32
    • 0030968984 scopus 로고    scopus 로고
    • Human temporal lobe potentials in verbal learning and memory processes
    • Elger CE, Grunwald T, Lehnertz K, et al. Human temporal lobe potentials in verbal learning and memory processes. Neuropsychologia. 1997;35:657-667.
    • (1997) Neuropsychologia , vol.35 , pp. 657-667
    • Elger, C.E.1    Grunwald, T.2    Lehnertz, K.3
  • 33
    • 0030917788 scopus 로고    scopus 로고
    • Single neuron activity in human hippocampus and amygdala during recognition of faces and objects
    • Fried I, MacDonald KA, Wilson CL. Single neuron activity in human hippocampus and amygdala during recognition of faces and objects. Neuron. 1997;18:753-765.
    • (1997) Neuron , vol.18 , pp. 753-765
    • Fried, I.1    MacDonald, K.A.2    Wilson, C.L.3
  • 34
    • 0032717269 scopus 로고    scopus 로고
    • Evidence relating human verbal memory to hippocampal N-methyl-D- aspartate receptors
    • Grunwald T, Beck H, Lehnertz K, et al. Evidence relating human verbal memory to hippocampal N-methyl-D- aspartate receptors. Proc Natl Acad Sci U S A. 1999;96:12085-12089.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12085-12089
    • Grunwald, T.1    Beck, H.2    Lehnertz, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.