-
1
-
-
33751502151
-
International Union of Pharmacology. LXVI. Orphan nuclear receptors
-
Benoit G, Cooney A, Giguere V, et al. International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev 2006; 58: 798-836.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 798-836
-
-
Benoit, G.1
Cooney, A.2
Giguere, V.3
-
2
-
-
0033542873
-
Medical significance of peroxisome proliferator-activated receptors
-
Vamecq J, Latruffe N. Medical significance of peroxisome proliferator-activated receptors. Lancet 1999; 354: 141-148.
-
(1999)
Lancet
, vol.354
, pp. 141-148
-
-
Vamecq, J.1
Latruffe, N.2
-
3
-
-
33847122993
-
Dual PPAR alpha/ gamma agonists: Promises and pitfalls in type 2 diabetes
-
Ahmed I, Furlong K, Flood J, Treat VP, Goldstein BJ. Dual PPAR alpha/ gamma agonists: promises and pitfalls in type 2 diabetes. Am J Ther 2007; 14: 49-62.
-
(2007)
Am J Ther
, vol.14
, pp. 49-62
-
-
Ahmed, I.1
Furlong, K.2
Flood, J.3
Treat, V.P.4
Goldstein, B.J.5
-
4
-
-
0028287666
-
Hyperinsulinaemia, obesity, and syndrome X
-
Zavaroni I, Bonini L, Fantuzzi M, Dall'Aglio E, Passeri M, Reaven GM. Hyperinsulinaemia, obesity, and syndrome X. J Intern Med 1994; 235: 51-56.
-
(1994)
J Intern Med
, vol.235
, pp. 51-56
-
-
Zavaroni, I.1
Bonini, L.2
Fantuzzi, M.3
Dall'Aglio, E.4
Passeri, M.5
Reaven, G.M.6
-
5
-
-
36749047983
-
The metabolic syndrome - a global challenge for prevention
-
Schwarz PE, Reiman M, Li J, et al. The metabolic syndrome - a global challenge for prevention. Horm Metab Res 2007; 39: 777-780.
-
(2007)
Horm Metab Res
, vol.39
, pp. 777-780
-
-
Schwarz, P.E.1
Reiman, M.2
Li, J.3
-
6
-
-
0347133334
-
Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes
-
Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004; 291: 335-342.
-
(2004)
JAMA
, vol.291
, pp. 335-342
-
-
Saydah, S.H.1
Fradkin, J.2
Cowie, C.C.3
-
7
-
-
26844431513
-
Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: The bezafibrate lessons
-
Tenenbaum A, Motro M, Fisman EZ. Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons. Cardiovasc Diabetol 2005; 4: 14-16.
-
(2005)
Cardiovasc Diabetol
, vol.4
, pp. 14-16
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
-
8
-
-
12344317202
-
Pleitropic effects of thiazolidinediones: Taking a look beyond antidiabetic activity
-
Giannini S, Serio M, Gali A. Pleitropic effects of thiazolidinediones: taking a look beyond antidiabetic activity. J Endocrinol Invest 2004; 27, 982-991.
-
(2004)
J Endocrinol Invest
, vol.27
, pp. 982-991
-
-
Giannini, S.1
Serio, M.2
Gali, A.3
-
9
-
-
34250213233
-
Evolution of peroxisome proliferator-activator receptor agonists
-
Chang F, Jaber LA, Berlie HD, O'Connel MB. Evolution of peroxisome proliferator-activator receptor agonists. Ann Pharmacother 2007; 41, 973-983.
-
(2007)
Ann Pharmacother
, vol.41
, pp. 973-983
-
-
Chang, F.1
Jaber, L.A.2
Berlie, H.D.3
O'Connel, M.B.4
-
10
-
-
33646255424
-
Peroxisome proliferator-activated receptor-gamma: Novel therapeutic target linking adiposity, insulin resistance, and atherosclerosis
-
Kepez A, Oto A, Dagdelen S. Peroxisome proliferator-activated receptor-gamma: novel therapeutic target linking adiposity, insulin resistance, and atherosclerosis. BioDrugs 2006; 20: 121-135.
-
(2006)
BioDrugs
, vol.20
, pp. 121-135
-
-
Kepez, A.1
Oto, A.2
Dagdelen, S.3
-
11
-
-
4444272941
-
Combination therapy with fenofibrate and rosiglitazone paradoxically lowers serum HDL cholesterol
-
Normen L, Frohlich J, Montaner J, Harris M, Elliott T, Bondy G. Combination therapy with fenofibrate and rosiglitazone paradoxically lowers serum HDL cholesterol. Diabetes Care 2004; 27: 2241-2242.
-
(2004)
Diabetes Care
, vol.27
, pp. 2241-2242
-
-
Normen, L.1
Frohlich, J.2
Montaner, J.3
Harris, M.4
Elliott, T.5
Bondy, G.6
-
12
-
-
29244437857
-
The effect of dual PPAR alpha/ gamma stimulation with combination of rosiglitazone and fenofibrate on metabolic parameters in type 2 diabetic patients
-
Seber S, Ucak S, Basat O, Altuntas Y. The effect of dual PPAR alpha/ gamma stimulation with combination of rosiglitazone and fenofibrate on metabolic parameters in type 2 diabetic patients. Diabetes Res Clin Pract 2006; 71: 52-58.
-
(2006)
Diabetes Res Clin Pract
, vol.71
, pp. 52-58
-
-
Seber, S.1
Ucak, S.2
Basat, O.3
Altuntas, Y.4
-
13
-
-
34447114640
-
Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus
-
Bajaj M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA. Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus. Diabetologis 2007; 50: 1723-1731
-
(2007)
Diabetologis
, vol.50
, pp. 1723-1731
-
-
Bajaj, M.1
Suraamornkul, S.2
Hardies, L.J.3
Glass, L.4
Musi, N.5
DeFronzo, R.A.6
-
14
-
-
34347333419
-
PPAR ligands: Are they potential agents for cardiovascular disorders?
-
Balakumar P, Rose M, Singh M. PPAR ligands: are they potential agents for cardiovascular disorders? Pharmacology 2007; 80: 177-184.
-
(2007)
Pharmacology
, vol.80
, pp. 177-184
-
-
Balakumar, P.1
Rose, M.2
Singh, M.3
-
15
-
-
34547625616
-
The next generation of PPAR drugs: Do we have the tools to find them?
-
Shearer BG, Billin AN. The next generation of PPAR drugs: do we have the tools to find them? Biochim Biophys Acta 2007; 1771: 1082-1093.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 1082-1093
-
-
Shearer, B.G.1
Billin, A.N.2
-
16
-
-
34548182594
-
PPAR dual agonists: Are they opening Pandora's Box?
-
Balakumar P, Rose M, Ganti SS, Krishan P, Singh M. PPAR dual agonists: are they opening Pandora's Box? Pharmacol Res 2007; 56: 91-98.
-
(2007)
Pharmacol Res
, vol.56
, pp. 91-98
-
-
Balakumar, P.1
Rose, M.2
Ganti, S.S.3
Krishan, P.4
Singh, M.5
-
18
-
-
13044286786
-
A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation
-
Oberfield JL, Collins JL, Holmes CP, et al. A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation. Proc Natl Acad Sci USA 1999; 96: 6102-6106.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6102-6106
-
-
Oberfield, J.L.1
Collins, J.L.2
Holmes, C.P.3
-
19
-
-
33845405222
-
ADOPT Study Group. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
-
Kahn SE, Haffner SM, Heise MA, et al. ADOPT Study Group. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006; 355: 2427-2443.
-
(2006)
N Engl J Med
, vol.355
, pp. 2427-2443
-
-
Kahn, S.E.1
Haffner, S.M.2
Heise, M.A.3
-
20
-
-
0036090467
-
Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation
-
Lecka-Czernik B, Moerman EJ, Grant DF, Lehmann JM, Manolagas SC, Jilka RL. Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 2002; 143: 2376-2384.
-
(2002)
Endocrinology
, vol.143
, pp. 2376-2384
-
-
Lecka-Czernik, B.1
Moerman, E.J.2
Grant, D.F.3
Lehmann, J.M.4
Manolagas, S.C.5
Jilka, R.L.6
-
21
-
-
13644257646
-
PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: Indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist
-
Bishop-Bailey D, Warner TD. PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist. FASEB J 2003; 17: 1925-1927.
-
(2003)
FASEB J
, vol.17
, pp. 1925-1927
-
-
Bishop-Bailey, D.1
Warner, T.D.2
-
22
-
-
2642557181
-
A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity
-
Rocchi S, Picard F, Vamecq J, et al. A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol Cell 2001; 8: 731-747.
-
(2001)
Mol Cell
, vol.8
, pp. 731-747
-
-
Rocchi, S.1
Picard, F.2
Vamecq, J.3
-
24
-
-
12444273748
-
Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator
-
Berger JP, Petro AE, Macnaul KL, et al. Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator. Mol Endocrinol 2003; 17: 662-676.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 662-676
-
-
Berger, J.P.1
Petro, A.E.2
Macnaul, K.L.3
-
25
-
-
0346668393
-
A non-thiazolidinedione partial peroxisome proliferator-activated receptor gamma ligand inhibits vascular smooth muscle cell growth
-
Bruemmer D, Berger JP, Liu J, et al. A non-thiazolidinedione partial peroxisome proliferator-activated receptor gamma ligand inhibits vascular smooth muscle cell growth. Eur J Pharmacol 2003; 466, 225-234.
-
(2003)
Eur J Pharmacol
, vol.466
, pp. 225-234
-
-
Bruemmer, D.1
Berger, J.P.2
Liu, J.3
-
26
-
-
29144474215
-
FK614, a novel peroxisome proliferator-activated receptor gamma modulator, induces differential transactivation through a unique ligand-specific interaction with transcriptional coactivators
-
Fujimura T, Sakuma H, Konishi S, et al. FK614, a novel peroxisome proliferator-activated receptor gamma modulator, induces differential transactivation through a unique ligand-specific interaction with transcriptional coactivators. J Pharmacol Sci 2005; 99: 342-352.
-
(2005)
J Pharmacol Sci
, vol.99
, pp. 342-352
-
-
Fujimura, T.1
Sakuma, H.2
Konishi, S.3
-
27
-
-
27744523803
-
Ameliorating effect of FK614, a novel nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist, on insulin resistance in Zucker fatty rat
-
Minoura H, Takeshita S, Yamamoto T, et al. Ameliorating effect of FK614, a novel nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist, on insulin resistance in Zucker fatty rat. Eur J Pharmacol 2005; 519: 182-190.
-
(2005)
Eur J Pharmacol
, vol.519
, pp. 182-190
-
-
Minoura, H.1
Takeshita, S.2
Yamamoto, T.3
-
28
-
-
42149110461
-
-
Malecha, J.W., Lindstrom, A.K., Duron, S.G., Govek, S.P.: WO07047432 ( 2007).
-
Malecha, J.W., Lindstrom, A.K., Duron, S.G., Govek, S.P.: WO07047432 ( 2007).
-
-
-
-
29
-
-
42149087309
-
-
Kalypsys, I., Zhao, C.: WO07109577 (2007).
-
Kalypsys, I., Zhao, C.: WO07109577 (2007).
-
-
-
-
30
-
-
42149175127
-
-
Lin, J., Womack, P., Lee, B., Shi, S., Zhang, C., Zuckerman, R., Artis, D.R., Ibrahim, P.N., Wang, W.: WO07030559 (2007).
-
Lin, J., Womack, P., Lee, B., Shi, S., Zhang, C., Zuckerman, R., Artis, D.R., Ibrahim, P.N., Wang, W.: WO07030559 (2007).
-
-
-
-
31
-
-
42149116512
-
-
Malecha, J.W., Lindstrom, A.K., Duron, S.G., Thomas, D.J.: WO07047431 (2007).
-
Malecha, J.W., Lindstrom, A.K., Duron, S.G., Thomas, D.J.: WO07047431 (2007).
-
-
-
-
32
-
-
42149191591
-
-
Epple, R., Cow, C.: WO07089557 (2007).
-
Epple, R., Cow, C.: WO07089557 (2007).
-
-
-
|