Attenuated endocytosis and toxicity of a mutant cholera toxin with decreased ability to cluster ganglioside GM1 molecules

Infection and Immunity

Volumn 76, Issue 4, 2008, Pages 1476-1484

  Wolf, Anne A ^a   Jobling, Michael G ^b   Saslowsky, David E ^a   Kern, Eli ^a   Drake, Kimberly R ^d   Kenworthy, Anne K ^d   Holmes, Randall K ^b   Lencer, Wayne I ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c HARVARD UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; GANGLIOSIDE GM1; PROTEIN SUBUNIT;

ARTICLE; BETA CHAIN; BINDING AFFINITY; CELL MEMBRANE; CELL SURFACE; CHIMERA; CONTROLLED STUDY; CROSS LINKING; DIFFUSION; ENDOCYTOSIS; HOST CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIPID RAFT; PRIORITY JOURNAL; WILD TYPE; CELL LINE; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TRANSPORT;

CELL LINE; CHOLERA TOXIN; ENDOCYTOSIS; G(M1) GANGLIOSIDE; HUMANS; MEMBRANE MICRODOMAINS; MUTATION; PROTEIN BINDING; PROTEIN SUBUNITS; PROTEIN TRANSPORT;

EID: 42149118541     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01286-07     Document Type: Article

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