Insulin qctivates ATP-sensitive potassium channels via phosphatidylinositol 3-kinase in cultured vascular smooth muscle cells

Journal of Vascular Research

Volumn 45, Issue 3, 2008, Pages 233-243

  Yasui, Sonoko ^a   Mawatari, Kazuaki ^a,c   Kawano, Takashi ^a   Morizumi, Ran ^a   Hamamoto, Akiko ^a   Furukawa, Hiroko ^a,b   Koyama, Kei ^a   Nakamura, Aki ^a   Hattori, Atsushi ^a   Nakano, Masayuki ^a   Harada, Nagakatsu ^a   Hosaka, Toshio ^a   Takahashi, Akira ^a   Oshita, Shuzo ^a   Nakaya, Yutaka ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KOCHI WOMEN S UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Hyperpolarization; Insulin; KATP channel; Nitric oxide synthase; PI3 K; Potassium channel; Vascular smooth muscle cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; BIS(1,3 DIBUTYLBARBITURIC ACID)TRIMETHINE OXONOL; DYE; GLIBENCLAMIDE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; NITRIC OXIDE SYNTHASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; WORTMANNIN; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; NITRIC OXIDE SYNTHASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; HYPERPOLARIZATION; ION TRANSPORT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; VASCULAR SMOOTH MUSCLE; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CYTOLOGY; INTRACELLULAR MEMBRANE; METABOLISM; OSMOLARITY; PHOSPHORYLATION; PHYSIOLOGY; SMOOTH MUSCLE FIBER; THORACIC AORTA; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANIMALS; AORTA, THORACIC; CELLS, CULTURED; INSULIN; INTRACELLULAR MEMBRANES; KATP CHANNELS; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE SYNTHASE; OSMOLAR CONCENTRATION; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTOR, INSULIN; TIME FACTORS;

EID: 42149097128     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000112545     Document Type: Article

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