Inhibitory effects of genistein on ATP-sensitive K+ channels in rabbit portal vein smooth muscle

British Journal of Pharmacology

Volumn 122, Issue 7, 1997, Pages 1395-1404

  Ogata, Rika ^a   Kitamura, Kenji ^b   Ito, Yushi ^a   Nakano, Hitoo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA DENTAL COLLEGE   (Japan)

Author keywords

ATP sensitive K+ channel; Ca2+ current; Genistein; K+ channel; Tyrosine kinase; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; BARIUM ION; DAIDZEIN; EPIDERMAL GROWTH FACTOR; GENISTEIN; GUANOSINE DIPHOSPHATE; GYRASE INHIBITOR; HERBIMYCIN A; LAVENDUSTIN A; PINACIDIL; POTASSIUM CHANNEL; PROTEIN TYROSINE KINASE; TYRPHOSTIN; VANADATE SODIUM; WORTMANNIN;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONDUCTANCE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG POTENCY; ELECTRIC POTENTIAL; MALE; NONHUMAN; PORTAL VEIN; POTASSIUM CURRENT; PRIORITY JOURNAL; RABBIT; VASCULAR SMOOTH MUSCLE;

EID: 0030829129     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701532     Document Type: Article

References (41)

1. AKIYAMA, T., ISHIDA, J., NAKAGAWA, S., OGAWARA, H., WATANABE, S., ITOH, N., SHIBUYA, M. & FUKAMI, Y. (1987). Genistein, a specific inhibitor of tyrosine protein kinases. J. Biol. Chem., 262, 5592-5595.
2. AKIYAMA, T. & OGAWARA, H. (1991). Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods Enzymol., 201, 362-370.
3. ARNOLD, R.S. & NEWTON, A.C. (1996). Diacylglycerol directly stimulates the insulin receptor tyrosine kinase. FEBS Lett., 380, 58-62.
4. FELDER, C.C. (1995). Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J., 9, 619-625.
5. HAMILL, O.P., MARTY, A., NEHER, E., SAKMANN, B. & SIGWORTH, F.J. (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch., 391, 85-100.
6. HATAKEYAMA, N., MUKHOPADHYAY, D., GOYAL, R.K. & AKBARALI, H.I. (1996). Tyrosine kinase-dependent modulation of calcium entry in rabbit colonic muscularis mucosae. Am. J. Physiol., 270, C1780-C1789.
7. HATAKEYAMA, N., WANG, Q., GOYAL, R.K. & AKBARALI, H.I. (1995). Muscarinic suppression of ATP-sensitive K+ channel in rabbit esophageal smooth muscle. Am. J. Physiol., 268, C877-C885.
8. HOLLENBERG, M.D. (1994). Tyrosine kinase pathways and the regulation of smooth muscle contractility. Trends Pharmacol. Sci., 15, 108-114.
9. HOPFIELD, J.F., TANK, D.W., GREENGARD, P. & HUGANIR, R.L. (1988). Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation. Nature, 336, 677-680.
10. HUANG, X-Y., MORIELLI, A.D. & PERALTA, E.G. (1993). Tyrosine kinase-dependent suppression of a potassium channel by the G-protein-coupled ml muscarinic acetylcholine receptor. Cell, 75, 1145-1156.
11. INAGAKI, N., TSUURA, Y., NAMBA, N., MASUDA, K., GONOI, T., HORIE, M., SEINO, Y., MIZUTA, M. & SEINO, S. (1995). Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle and heart. J. Biol. Chem., 270, 5691-5694.
12. INOUE, R., WANIISHI, K., YAMADA, K. & ITO, Y. (1994). A possible role of tyrosine kinases in regulation of muscarinic receptor-activated cation channels in guinea pig ileum. Biochem. Biophys. Res. Commun., 203, 1392-1397.
13. + channel in the rabbit portal vein. J. Physiol., 444, 397-418.
14. + channels by ATP and nucleotide diphosphate in rabbit portal vein. Am. J. Physiol., 266, H1687-H1698.
15. KUSAKA, M. & SPERELAKIS, N. (1996). Inhibition of L-type calcium current by genistein, a tyrosine kinase inhibitor, in pregnant rat myometrial cells. Biochim. Biophys. Acta, 1240, 196-200.
16. + channel activity in rat ventricular myocytes by phosphorylation of tyrosine and serine/threonine residues. Life Sci., 11, 897-904.
17. 2+-induced regulation of ion channel and MAP kinase function. Nature 376, 737-745.
18. MATSUMOTO, P.S., OHARA, A., DUCHATELLE, P. & EATON, D.C. (1993). Tyrosine kinase regulates epithelial sodium transport in A6 cells. Am. J. Physiol., 264, C246-C250.
19. A receptors by tyrosine phosphorylation. Nature, 377, 344-348.
20. NAKANISHI, S., KAKITA, S., TAKAHASHI, I., KAWAHARA, K., TSUKUDA, E., SANO, T., YAMADA, K., YOSHIDA, M., KASE, H., MATSUDA, Y., HASHIMOTO, Y. & NONOMURA, Y. (1992). Wortmannin, a microbial product inhibitor of myosin light chain kinase. J. Biol. Chem., 267, 2157-2163.
21. O'DELL, T.J., KANDEL, E.R. & GRANT, S.G.H. (1991). Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature, 363, 558-560.
22. ONODA, T., IINUMA, H., SASAKI, Y., HAMADA, M., ISSIKI, K., NAGANAWA, H., TAKEUCHI, T., TATSUTA, K. & UMEZAWA, K. (1989). Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus. J. Nat. Prod., 52, 1252-1257.
23. ONODA, T., ISSIKI, K., TAKEUCHI, T., TATSUTA, K. & UMEZAWA, K. (1990). Inhibition of tyrosine kinase and epidermal growth factor receptor internalization by lavendustin A methyl ester in cultured A431 cells. Drugs Exp. Clin. Res., 16, 249-253.
24. PAILLART, C., CARLIER, E., GUEDIN, D., DARGENT, B. & COURAUD, F. (1997). Direct block of voltage-sensitive sodium channels by genistein, a tyrosine kinase inhibitor. J. Pharmacol. Exp. Ther., 280, 521-526.
25. QUAYLE, J.M., BONEV, A.D., BRAYDEN, J.E. & NELSON, M.T. (1994). Calcitonin gene-related peptide activated ATP-sensitive K+ currents in rabbit arterial smooth muscle via protein kinase A. J. Physiol., 475, 9-13.
26. RAEYMAEKERS, L., WUYTACK, F., EGGERMONT, J., DE SCHUTTER, G. & CASTEELS, R. (1983). Isolation of a plasma-membrane fraction from gastric smooth muscle. Comparison of the calcium uptake with that in endoplasmic reticulum. Biochem. J., 210, 314-322.
27. SEARLE, B.M., HIGASHINO, H., KHALIL, F. & BOGDEN, J.D. (1983). Vanadate effect on the Na, K-ATPase and the Na-K pump in in vitro-grown rat vascular smooth muscle cells. Circ. Res., 53, 186-191.
28. + currents by tyrosine kinase inhibitors genistein and ST 638. Circ. Res., 76, 310-316.
29. SOROTA, S. (1995). Tyrosine protein kinase inhibitors prevent activation of cardiac swelling-induced chloride current. Pflügers Arch., 431, 178-185.
30. SWOPE, S.L., QU, Z. & HUGANIR, R.L. (1995). Phosphorylation of the nicotinic acetylcholine receptor by protein tyrosine kinases. Ann. N.Y. Acad. Sci., 757, 197-214.
31. TILLY, B.C., VAN DEN BERGHE, N., TERTOOLEN, L.G.J., EDIXHOVEN, M.J. & DEJONGE, H.R. (1993). Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances. J. Biol. Chem., 268, 19919-19922.
32. TSUDA, T., KAWAHARA, Y., SHII, K., KOIDE, M., ISHIDA, Y. & YOKOYAMA, M. (1991). Vasoconstrictor-induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells. FEBS Letts, 285, 44-48.
33. + channel in ventricular cell of guinea-pig. J. Physiol., 437, 239-256.
34. UEHARA, Y. & FUKAZAWA, H. (1991). Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases. Methods Enzymol., 201, 370-379.
35. VAN DER GEER, P., HUNTER, T. & LINDBERG, R.A. (1994). Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol., 10, 251-337.
36. WANG, Y.T. & SALTER, M.W. (1994). Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature, 369, 233-235.
37. WIJETUNGE, S. & HUGHES, A.D. (1995). Effects of platelet-derived growth factor on voltage-operated calcium channels in rabbit isolated ear artery cells. Br. J. Pharmacol., 115, 534-538.
38. WIJETUNGE, S., AALKJAER, C., SCHACHTER, M. & HUGHES, A.D. (1992). Tyrosine kinase inhibitors block calcium channel currents in vascular smooth muscle cells. Biochem. Biophys. Res. Commun., 189, 1620-1623.
39. WILLIAMS, L.T. (1989). Signal transduction by the platelet-derived growth factor receptor. Science, 243, 1564-1570.
40. + channels in vascular smooth muscle cells by neuropeptide Y. Pflügers Arch., 431, 110-116.
41. YANO, H., NAKANISHI, S., KIMURA, K., HANAI, N., SAITOH, Y., FUKUI, Y., NONOMURA, Y. & MATSUDA, Y. (1993). Inhibition of histamine secretion by wortmannin through the blockade of phosphatidyl inositol 3-kinase in RBL-2H3 cells. J. Biol. Chem., 268, 25846-25856.