-
1
-
-
0034162763
-
Developmentally distinct effects on human epsilon-, gamma- and delta-globin levels caused by the absence or altered position of the human beta-globin gene in YAC transgenic mice
-
Bauchwitz, R. Costantini, F. (2000) Developmentally distinct effects on human epsilon-, gamma- and delta-globin levels caused by the absence or altered position of the human beta-globin gene in YAC transgenic mice. Human Molecular Genetics, 9, 561 574.
-
(2000)
Human Molecular Genetics
, vol.9
, pp. 561-574
-
-
Bauchwitz, R.1
Costantini, F.2
-
2
-
-
0033558362
-
Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression
-
Calzolari, R., McMorrow, T., Yannoutsos, N., Langeveld, A. Grosveld, F. (1999) Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression. The EMBO Journal, 18, 949 958.
-
(1999)
The EMBO Journal
, vol.18
, pp. 949-958
-
-
Calzolari, R.1
McMorrow, T.2
Yannoutsos, N.3
Langeveld, A.4
Grosveld, F.5
-
3
-
-
0036898580
-
Long-range chromatin regulatory interactions in vivo
-
Carter, D., Chakalova, L., Osborne, C.S., Dai, Y.F. Fraser, P. (2002) Long-range chromatin regulatory interactions in vivo. Nature Genetics, 32, 623 626.
-
(2002)
Nature Genetics
, vol.32
, pp. 623-626
-
-
Carter, D.1
Chakalova, L.2
Osborne, C.S.3
Dai, Y.F.4
Fraser, P.5
-
4
-
-
14944379039
-
The Corfu deltabeta thalassemia deletion disrupts gamma-globin gene silencing and reveals post-transcriptional regulation of HbF expression
-
Chakalova, L., Osborne, C.S., Dai, Y.F., Goyenechea, B., Metaxotou-Mavromati, A., Kattamis, A., Kattamis, C. Fraser, P. (2005) The Corfu deltabeta thalassemia deletion disrupts gamma-globin gene silencing and reveals post-transcriptional regulation of HbF expression. Blood, 105, 2154 2160.
-
(2005)
Blood
, vol.105
, pp. 2154-2160
-
-
Chakalova, L.1
Osborne, C.S.2
Dai, Y.F.3
Goyenechea, B.4
Metaxotou-Mavromati, A.5
Kattamis, A.6
Kattamis, C.7
Fraser, P.8
-
5
-
-
0033849663
-
Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding
-
Cobb, B.S., Morales-Alcelay, S., Kleiger, G., Brown, K.E., Fisher, A.G. Smale, S.T. (2000) Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes and Development, 14, 2146 2160.
-
(2000)
Genes and Development
, vol.14
, pp. 2146-2160
-
-
Cobb, B.S.1
Morales-Alcelay, S.2
Kleiger, G.3
Brown, K.E.4
Fisher, A.G.5
Smale, S.T.6
-
6
-
-
0037083376
-
Capturing chromosome conformation
-
Dekker, J., Rippe, K., Dekker, M. Kleckner, N. (2002) Capturing chromosome conformation. Science, 295, 1306 1311.
-
(2002)
Science
, vol.295
, pp. 1306-1311
-
-
Dekker, J.1
Rippe, K.2
Dekker, M.3
Kleckner, N.4
-
7
-
-
42049086258
-
The role of Ikaros in human erythroid differentiation
-
doi:.
-
Dijon, M., Bardin, F., Murati, A., Batoz, M., Chabannon, C. Tonnelle, C. (2007) The role of Ikaros in human erythroid differentiation. Blood, doi:.
-
(2007)
Blood
-
-
Dijon, M.1
Bardin, F.2
Murati, A.3
Batoz, M.4
Chabannon, C.5
Tonnelle, C.6
-
8
-
-
5444255213
-
The active spatial organization of the beta-globin locus requires the transcription factor EKLF
-
Drissen, R., Palstra, R.J., Gillemans, N., Splinter, E., Grosveld, F., Philipsen, S. de Laat, W. (2004) The active spatial organization of the beta-globin locus requires the transcription factor EKLF. Genes and Development, 18, 2485 2490.
-
(2004)
Genes and Development
, vol.18
, pp. 2485-2490
-
-
Drissen, R.1
Palstra, R.J.2
Gillemans, N.3
Splinter, E.4
Grosveld, F.5
Philipsen, S.6
De Laat, W.7
-
9
-
-
23344450922
-
Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5′HS3 deletion mutations: Implication for LCR chromatin architecture
-
Fang, X., Sun, J., Xiang, P., Yu, M., Navas, P.A., Peterson, K.R., Stamatoyannopoulos, G. Li, Q. (2005) Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5′HS3 deletion mutations: implication for LCR chromatin architecture. Molecular and Cellular Biology, 25, 7033 7041.
-
(2005)
Molecular and Cellular Biology
, vol.25
, pp. 7033-7041
-
-
Fang, X.1
Sun, J.2
Xiang, P.3
Yu, M.4
Navas, P.A.5
Peterson, K.R.6
Stamatoyannopoulos, G.7
Li, Q.8
-
10
-
-
0027443269
-
Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice
-
Gaensler, K.M., Kitamura, M. Kan, Y.W. (1993) Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice. Proceedings of the National Academy of Sciences USA, 90, 11381 11385.
-
(1993)
Proceedings of the National Academy of Sciences USA
, vol.90
, pp. 11381-11385
-
-
Gaensler, K.M.1
Kitamura, M.2
Kan, Y.W.3
-
11
-
-
0037452970
-
Sequences in the (A)gamma-delta intergenic region are not required for stage-specific regulation of the human beta-globin gene locus
-
Gaensler, K.M., Zhang, Z., Lin, C., Yang, S., Hardt, K. Flebbe-Rehwaldt, L. (2003) Sequences in the (A)gamma-delta intergenic region are not required for stage-specific regulation of the human beta-globin gene locus. Proceedings of the National Academy of Sciences USA, 100, 3374 3379.
-
(2003)
Proceedings of the National Academy of Sciences USA
, vol.100
, pp. 3374-3379
-
-
Gaensler, K.M.1
Zhang, Z.2
Lin, C.3
Yang, S.4
Hardt, K.5
Flebbe-Rehwaldt, L.6
-
12
-
-
0036519296
-
Haematopoietic cell-fate decisions, chromatin regulation and ikaros
-
Georgopoulos, K. (2002) Haematopoietic cell-fate decisions, chromatin regulation and ikaros. Nature Reviews Immunology, 2, 162 174.
-
(2002)
Nature Reviews Immunology
, vol.2
, pp. 162-174
-
-
Georgopoulos, K.1
-
13
-
-
0028001362
-
The Ikaros gene is required for the development of all lymphoid lineages
-
Georgopoulos, K., Bigby, M., Wang, J.H., Molnar, A., Wu, P., Winandy, S. Sharpe, A. (1994) The Ikaros gene is required for the development of all lymphoid lineages. Cell, 79, 143 156.
-
(1994)
Cell
, vol.79
, pp. 143-156
-
-
Georgopoulos, K.1
Bigby, M.2
Wang, J.H.3
Molnar, A.4
Wu, P.5
Winandy, S.6
Sharpe, A.7
-
14
-
-
0033853988
-
Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus
-
Gribnau, J., Diderich, K., Pruzina, S., Calzolari, R. Fraser, P. (2000) Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus. Molecular Cell, 5, 377 386.
-
(2000)
Molecular Cell
, vol.5
, pp. 377-386
-
-
Gribnau, J.1
Diderich, K.2
Pruzina, S.3
Calzolari, R.4
Fraser, P.5
-
15
-
-
0028152483
-
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene
-
Hahm, K., Ernst, P., Lo, K., Kim, G.S., Turck, C. Smale, S.T. (1994) The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. Molecular and Cellular Biology, 14, 7111 7123.
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 7111-7123
-
-
Hahm, K.1
Ernst, P.2
Lo, K.3
Kim, G.S.4
Turck, C.5
Smale, S.T.6
-
16
-
-
33645743530
-
A global role for EKLF in definitive and primitive erythropoiesis
-
Hodge, D., Coghill, E., Keys, J., Maguire, T., Hartmann, B., McDowall, A., Weiss, M., Grimmond, S. Perkins, A. (2006) A global role for EKLF in definitive and primitive erythropoiesis. Blood, 107, 3359 3370.
-
(2006)
Blood
, vol.107
, pp. 3359-3370
-
-
Hodge, D.1
Coghill, E.2
Keys, J.3
Maguire, T.4
Hartmann, B.5
McDowall, A.6
Weiss, M.7
Grimmond, S.8
Perkins, A.9
-
17
-
-
0037022675
-
GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis
-
Horak, C.E., Mahajan, M.C., Luscombe, N.M., Gerstein, M., Weissman, S.M. Snyder, M. (2002) GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. Proceedings of the National Academy of Sciences USA, 99, 2924 2929.
-
(2002)
Proceedings of the National Academy of Sciences USA
, vol.99
, pp. 2924-2929
-
-
Horak, C.E.1
Mahajan, M.C.2
Luscombe, N.M.3
Gerstein, M.4
Weissman, S.M.5
Snyder, M.6
-
18
-
-
0029959548
-
Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter
-
Jackson, J.D., Miller, W. Hardison, R.C. (1996) Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter. Nucleic Acids Research, 24, 4327 4335.
-
(1996)
Nucleic Acids Research
, vol.24
, pp. 4327-4335
-
-
Jackson, J.D.1
Miller, W.2
Hardison, R.C.3
-
19
-
-
0033103374
-
Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
-
Kim, J., Sif, S., Jones, B., Jackson, A., Koipally, J., Heller, E., Winandy, S., Viel, A., Sawyer, A., Ikeda, T., Kingston, R. Georgopoulos, K. (1999) Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity, 10, 345 355.
-
(1999)
Immunity
, vol.10
, pp. 345-355
-
-
Kim, J.1
Sif, S.2
Jones, B.3
Jackson, A.4
Koipally, J.5
Heller, E.6
Winandy, S.7
Viel, A.8
Sawyer, A.9
Ikeda, T.10
Kingston, R.11
Georgopoulos, K.12
-
20
-
-
0034733563
-
Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity
-
Koipally, J. Georgopoulos, K. (2000) Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. Journal of Biological Chemistry, 275, 19594 19602.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 19594-19602
-
-
Koipally, J.1
Georgopoulos, K.2
-
21
-
-
0037066767
-
Unconventional potentiation of gene expression by Ikaros
-
Koipally, J., Heller, E.J., Seavitt, J.R. Georgopoulos, K. (2002) Unconventional potentiation of gene expression by Ikaros. Journal of Biological Chemistry, 277, 13007 13015.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 13007-13015
-
-
Koipally, J.1
Heller, E.J.2
Seavitt, J.R.3
Georgopoulos, K.4
-
22
-
-
34447536151
-
Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice
-
Kooren, J., Palstra, R.J., Klous, P., Splinter, E., von Lindern, M., Grosveld, F. de Laat, W. (2007) Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice. Journal of Biological Chemistry, 282, 16544 16552.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 16544-16552
-
-
Kooren, J.1
Palstra, R.J.2
Klous, P.3
Splinter, E.4
Von Lindern, M.5
Grosveld, F.6
De Laat, W.7
-
23
-
-
0023851667
-
The Corfu delta beta zero thalassemia: A small deletion acts at a distance to selectively abolish beta globin gene expression
-
Kulozik, A.E., Yarwood, N. Jones, R.W. (1988) The Corfu delta beta zero thalassemia: a small deletion acts at a distance to selectively abolish beta globin gene expression. Blood, 71, 457 462.
-
(1988)
Blood
, vol.71
, pp. 457-462
-
-
Kulozik, A.E.1
Yarwood, N.2
Jones, R.W.3
-
24
-
-
7444264527
-
Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter
-
Liu, M., Whetstine, J.R., Payton, S.G., Ge, Y., Flatley, R.M. Matherly, L.H. (2004) Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter. Biochemical Journal, 383, 249 257.
-
(2004)
Biochemical Journal
, vol.383
, pp. 249-257
-
-
Liu, M.1
Whetstine, J.R.2
Payton, S.G.3
Ge, Y.4
Flatley, R.M.5
Matherly, L.H.6
-
25
-
-
0037154228
-
Multiple hematopoietic defects and delayed globin switching in Ikaros null mice
-
Lopez, R.A., Schoetz, S., DeAngelis, K., O'Neill, D. Bank, A. (2002) Multiple hematopoietic defects and delayed globin switching in Ikaros null mice. Proceedings of the National Academy of Sciences USA, 99, 602 607.
-
(2002)
Proceedings of the National Academy of Sciences USA
, vol.99
, pp. 602-607
-
-
Lopez, R.A.1
Schoetz, S.2
Deangelis, K.3
O'Neill, D.4
Bank, A.5
-
26
-
-
0035051594
-
Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement
-
Molete, J.M., Petrykowska, H., Bouhassira, E.E., Feng, Y.Q., Miller, W. Hardison, R.C. (2001) Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement. Molecular and Cellular Biology, 21, 2969 2980.
-
(2001)
Molecular and Cellular Biology
, vol.21
, pp. 2969-2980
-
-
Molete, J.M.1
Petrykowska, H.2
Bouhassira, E.E.3
Feng, Y.Q.4
Miller, W.5
Hardison, R.C.6
-
27
-
-
0033582269
-
Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching
-
O'Neill, D., Yang, J., Erdjument-Bromage, H., Bornschlegel, K., Tempst, P. Bank, A. (1999) Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching. Proceedings of the National Academy of Sciences USA, 96, 349 354.
-
(1999)
Proceedings of the National Academy of Sciences USA
, vol.96
, pp. 349-354
-
-
O'Neill, D.1
Yang, J.2
Erdjument-Bromage, H.3
Bornschlegel, K.4
Tempst, P.5
Bank, A.6
-
28
-
-
0033805828
-
An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells
-
O'Neill, D.W., Schoetz, S.S., Lopez, R.A., Castle, M., Rabinowitz, L., Shor, E., Krawchuk, D., Goll, M.G., Renz, M., Seelig, H.P., Han, S., Seong, R.H., Park, S.D., Agalioti, T., Munshi, N., Thanos, D., Erdjument-Bromage, H., Tempst, P. Bank, A. (2000) An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells. Molecular and Cellular Biology, 20, 7572 7582.
-
(2000)
Molecular and Cellular Biology
, vol.20
, pp. 7572-7582
-
-
O'Neill, D.W.1
Schoetz, S.S.2
Lopez, R.A.3
Castle, M.4
Rabinowitz, L.5
Shor, E.6
Krawchuk, D.7
Goll, M.G.8
Renz, M.9
Seelig, H.P.10
Han, S.11
Seong, R.H.12
Park, S.D.13
Agalioti, T.14
Munshi, N.15
Thanos, D.16
Erdjument-Bromage, H.17
Tempst, P.18
Bank, A.19
-
29
-
-
0141730403
-
The beta-globin nuclear compartment in development and erythroid differentiation
-
Palstra, R.J., Tolhuis, B., Splinter, E., Nijmeijer, R., Grosveld, F. de Laat, W. (2003) The beta-globin nuclear compartment in development and erythroid differentiation. Nature Genetics, 35, 190 194.
-
(2003)
Nature Genetics
, vol.35
, pp. 190-194
-
-
Palstra, R.J.1
Tolhuis, B.2
Splinter, E.3
Nijmeijer, R.4
Grosveld, F.5
De Laat, W.6
-
30
-
-
0038106526
-
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
-
Papathanasiou, P., Perkins, A.C., Cobb, B.S., Ferrini, R., Sridharan, R., Hoyne, G.F., Nelms, K.A., Smale, S.T. Goodnow, C.C. (2003) Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity, 19, 131 144.
-
(2003)
Immunity
, vol.19
, pp. 131-144
-
-
Papathanasiou, P.1
Perkins, A.C.2
Cobb, B.S.3
Ferrini, R.4
Sridharan, R.5
Hoyne, G.F.6
Nelms, K.A.7
Smale, S.T.8
Goodnow, C.C.9
-
31
-
-
2942657608
-
Multiple interactions between regulatory regions are required to stabilize an active chromatin hub
-
Patrinos, G.P., de Krom, M., de Boer, E., Langeveld, A., Imam, A.M., Strouboulis, J., de Laat, W. Grosveld, F.G. (2004) Multiple interactions between regulatory regions are required to stabilize an active chromatin hub. Genes and Development, 18, 1495 1509.
-
(2004)
Genes and Development
, vol.18
, pp. 1495-1509
-
-
Patrinos, G.P.1
De Krom, M.2
De Boer, E.3
Langeveld, A.4
Imam, A.M.5
Strouboulis, J.6
De Laat, W.7
Grosveld, F.G.8
-
32
-
-
0034623943
-
Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities
-
Perdomo, J., Holmes, M., Chong, B. Crossley, M. (2000) Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities. Journal of Biological Chemistry, 275, 38347 38354.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 38347-38354
-
-
Perdomo, J.1
Holmes, M.2
Chong, B.3
Crossley, M.4
-
33
-
-
0027261194
-
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes
-
Peterson, K.R., Clegg, C.H., Huxley, C., Josephson, B.M., Haugen, H.S., Furukawa, T. Stamatoyannopoulos, G. (1993) Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes. Proceedings of the National Academy of Sciences USA, 90, 7593 7597.
-
(1993)
Proceedings of the National Academy of Sciences USA
, vol.90
, pp. 7593-7597
-
-
Peterson, K.R.1
Clegg, C.H.2
Huxley, C.3
Josephson, B.M.4
Haugen, H.S.5
Furukawa, T.6
Stamatoyannopoulos, G.7
-
34
-
-
0036923833
-
Looping and interaction between hypersensitive sites in the active beta-globin locus
-
Tolhuis, B., Palstra, R.J., Splinter, E., Grosveld, F. de Laat, W. (2002) Looping and interaction between hypersensitive sites in the active beta-globin locus. Molecular Cell, 10, 1453 1465.
-
(2002)
Molecular Cell
, vol.10
, pp. 1453-1465
-
-
Tolhuis, B.1
Palstra, R.J.2
Splinter, E.3
Grosveld, F.4
De Laat, W.5
-
35
-
-
13244272059
-
Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1
-
Vakoc, C.R., Letting, D.L., Gheldof, N., Sawado, T., Bender, M.A., Groudine, M., Weiss, M.J., Dekker, J. Blobel, G.A. (2005) Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Molecular Cell, 17, 453 462.
-
(2005)
Molecular Cell
, vol.17
, pp. 453-462
-
-
Vakoc, C.R.1
Letting, D.L.2
Gheldof, N.3
Sawado, T.4
Bender, M.A.5
Groudine, M.6
Weiss, M.J.7
Dekker, J.8
Blobel, G.A.9
-
36
-
-
0029051646
-
Transcription complex stability and chromatin dynamics in vivo
-
Wijgerde, M., Grosveld, F. Fraser, P. (1995) Transcription complex stability and chromatin dynamics in vivo. Nature, 377, 209 213.
-
(1995)
Nature
, vol.377
, pp. 209-213
-
-
Wijgerde, M.1
Grosveld, F.2
Fraser, P.3
-
37
-
-
23644439417
-
STAT4 is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells
-
Yap, W.H., Yeoh, E., Tay, A., Brenner, S. Venkatesh, B. (2005) STAT4 is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells. FEBS Letters, 579, 4470 4478.
-
(2005)
FEBS Letters
, vol.579
, pp. 4470-4478
-
-
Yap, W.H.1
Yeoh, E.2
Tay, A.3
Brenner, S.4
Venkatesh, B.5
-
38
-
-
33645109285
-
Early hematopoietic lineage restrictions directed by Ikaros
-
Yoshida, T., Ng, S.Y., Zuniga-Pflucker, J.C. Georgopoulos, K. (2006) Early hematopoietic lineage restrictions directed by Ikaros. Nature Immunology, 7, 382 391.
-
(2006)
Nature Immunology
, vol.7
, pp. 382-391
-
-
Yoshida, T.1
Ng, S.Y.2
Zuniga-Pflucker, J.C.3
Georgopoulos, K.4
-
39
-
-
33744943818
-
Differential binding of erythroid Krupple-like factor to embryonic/fetal globin gene promoters during development
-
Zhou, D., Pawlik, K.M., Ren, J., Sun, C.W. Townes, T.M. (2006) Differential binding of erythroid Krupple-like factor to embryonic/fetal globin gene promoters during development. Journal of Biological Chemistry, 281, 16052 16057.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 16052-16057
-
-
Zhou, D.1
Pawlik, K.M.2
Ren, J.3
Sun, C.W.4
Townes, T.M.5
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