Epigenetic and genetic analysis of the survivin promoter in acute myeloid leukemia

Leukemia Research

Volumn 32, Issue 7, 2008, Pages 1054-1060

  Wagner, Mandy ^a   Schmelz, Karin ^a   Dörken, Bernd ^a   Tamm, Ingo ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Acute myeloid leukemia; DNA methylation; Polymorphism; Promoter; Survivin; Transcription

Indexed keywords

SURVIVIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENETIC ANALYSIS; HUMAN; HUMAN CELL; LEUKEMOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

BASE SEQUENCE; CELL LINE, TUMOR; DNA METHYLATION; DNA PRIMERS; EPIGENESIS, GENETIC; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROMOTER REGIONS (GENETICS);

EID: 41949141312     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2007.11.013     Document Type: Article

References (34)

1. O'Connor D.S., Grossman D., Plescia J., Li F., Zhang H., Villa A., et al. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci USA 97 (2000) 13103-13107
2. Marusawa H., Matsuzawa S., Welsh K., Zou H., Armstrong R., Tamm I., et al. HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J 22 (2003) 2729-2740
3. Li F., Ackermann E.J., Bennett C.F., Rothermel A.L., Plescia J., Tognin S., et al. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol 1 (1999) 461-466
4. Ambrosini G., Adida C., and Altieri D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 3 (1997) 917-921
5. Adida C., Berrebi D., Peuchmaur M., Reyes-Mugica M., and Altieri D.C. Anti-apoptosis gene, survivin, and prognosis of neuroblastoma. Lancet 351 (1998) 882-883
6. Islam A., Kageyama H., Hashizume K., Kaneko Y., and Nakagawara A. Role of survivin, whose gene is mapped to 17q25, in human neuroblastoma and identification of a novel dominant-negative isoform, survivin-beta/2B. Med Pediatr Oncol 35 (2000) 550-553
7. Wagner M., Schmelz K., Wuchter C., Ludwig W.D., Dörken B., and Tamm I. In vivo expression of survivin and its splice variant survivin-2B: impact on clinical outcome in acute myeloid leukemia. Int J Cancer 119 (2006) 1291-1297
8. Kawasaki H., Altieri D.C., Lu C.D., Toyoda M., Tenjo T., and Tanigawa N. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res 58 (1998) 5071-5074
9. Li F., Ambrosini G., Chu E.Y., Plescia J., Tognin S., Marchisio P.C., et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396 (1998) 580-584
10. Altieri D.C. Validating survivin as a cancer therapeutic target. Nat Rev Cancer 3 (2003) 46-54
11. Li F. Survivin study: what is the next wave?. J Cell Physiol 197 (2003) 8-29
12. Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat Rev Genet 3 (2002) 415-428
13. Baylin S.B., and Herman J.G. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 16 (2000) 168-174
14. Robertson K.D. DNA methylation, methyltransferases, and cancer. Oncogene 20 (2001) 3139-3155
15. Hattori M., Sakamoto H., Satoh K., and Yamamoto T. DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes. Cancer Lett 169 (2001) 155-164
16. Yu J., Ni M., Xu J., Zhang H., Gao B., Gu J., et al. Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. BMC Cancer 2 (2002) 29
17. Tanaka C., Uzawa K., Shibahara T., Yokoe H., Noma H., and Tanzawa H. Expression of an inhibitor of apoptosis, survivin, in oral carcinogenesis. J Dent Res 82 (2003) 607-611
18. Yu J., Zhang H., Gu J., Lin S., Li J., Lu W., et al. Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer 4 (2004) 65
19. Xu Y., Fang F., Ludewig G., Jones G., and Jones D. A mutation found in the promoter region of the human survivin gene is correlated to overexpression of survivin in cancer cells. DNA Cell Biol 23 (2004) 527-537
20. Li F., and Altieri D.C. The cancer antiapoptosis mouse survivin gene: characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression. Cancer Res 59 (1999) 3143-3151
21. Li F., and Altieri D.C. Transcriptional analysis of human survivin gene expression. Biochem J 344 (1999) 305-311
22. Orita M., Suzuki Y., Sekiya T., and Hayashi K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5 (1989) 874-879
23. Borbely A.A., Murvai M., Szarka K., Konya J., Gergely L., Hernadi Z., et al. Survivin promoter polymorphism and cervical carcinogenesis. J Clin Pathol 60 (2007) 303-306
24. Sakai T., Toguchida J., Ohtani N., Yandell D.W., Rapaport J.M., and Dryja T.P. Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene. Am J Hum Genet 48 (1991) 880-888
25. Herman J.G., Merlo A., Mao L., Lapidus R.G., Issa J.P., Davidson N.E., et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55 (1995) 4525-4530
26. Ng M.H., Chung Y.F., Lo K.W., Wickham N.W., Lee J.C., and Huang D.P. Frequent hypermethylation of p16 and p15 genes in multiple myeloma. Blood 89 (1997) 2500-2506
27. Hanada M., Delia D., Aiello A., Stadtmauer E., and Reed J.C. bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 82 (1993) 1820-1828
28. Feinberg A.P., and Vogelstein B. Hypomethylation of ras oncogenes in primary human cancers. Biochem Biophys Res Commun 111 (1983) 47-54
29. Hoffman W.H., Biade S., Zilfou J.T., Chen J., and Murphy M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 277 (2002) 3247-3257
30. Juan L.J., Shia W.J., Chen M.H., Yang W.M., Seto E., Lin Y.S., et al. Histone deacetylases specifically down-regulate p53-dependent gene activation. J Biol Chem 275 (2000) 20436-20443
31. Esteve P.O., Chin H.G., and Pradhan S. Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters. Proc Natl Acad Sci USA 102 (2005) 1000-1005
32. Esteve P.O., Chin H.G., and Pradhan S. Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells. J Biol Chem 282 (2007) 2615-2625
33. Nakano Y., Naoe T., Kiyoi H., Kitamura K., Minami S., Miyawaki S., et al. Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia. Eur J Haematol 65 (2000) 23-31
34. Stirewalt D.L., and Radich J.P. Malignancy: tumor suppressor gene aberrations in acute myelogenous leukemia. Hematology 5 (2000) 15-25