-
1
-
-
0037212977
-
Role of endothelial cells in early pancreas and liver development
-
Lammert E, Cleaver O, Melton D. Role of endothelial cells in early pancreas and liver development. Mech Dev 2003; 120:59-64.
-
(2003)
Mech Dev
, vol.120
, pp. 59-64
-
-
Lammert, E.1
Cleaver, O.2
Melton, D.3
-
2
-
-
33644537403
-
The vascular basement membrane: A niche for insulin gene expression and Beta cell proliferation
-
Nikolova G, Jabs N, Konstantinova I, et al. The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. Dev Cell 2006; 10:397-405.
-
(2006)
Dev Cell
, vol.10
, pp. 397-405
-
-
Nikolova, G.1
Jabs, N.2
Konstantinova, I.3
-
4
-
-
34547931078
-
Modeling tissue morphogenesis and cancer in 3D
-
Yamada KM, Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 2007; 130:601-610.
-
(2007)
Cell
, vol.130
, pp. 601-610
-
-
Yamada, K.M.1
Cukierman, E.2
-
5
-
-
0034870220
-
Differential gene expression during capillary morphogenesis in 3D collagen matrices: Regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling
-
Bell SE, Mavila A, Salazar R, et al. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. J Cell Sci 2001; 114:2755-2773.
-
(2001)
J Cell Sci
, vol.114
, pp. 2755-2773
-
-
Bell, S.E.1
Mavila, A.2
Salazar, R.3
-
6
-
-
0036829020
-
Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices
-
Davis GE, Bayless KJ, Mavila A. Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices. Anat Rec 2002; 268:252-275.
-
(2002)
Anat Rec
, vol.268
, pp. 252-275
-
-
Davis, G.E.1
Bayless, K.J.2
Mavila, A.3
-
7
-
-
33748799968
-
Molecular balance of capillary tube formation versus regression in wound repair: Role of matrix metalloproteinases and their inhibitors
-
Davis GE, Saunders WB. Molecular balance of capillary tube formation versus regression in wound repair: role of matrix metalloproteinases and their inhibitors. J Investig Dermatol Symp Proc 2006; 11:44-56.
-
(2006)
J Investig Dermatol Symp Proc
, vol.11
, pp. 44-56
-
-
Davis, G.E.1
Saunders, W.B.2
-
8
-
-
33644683263
-
Endothelial extracellular matrix: Biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
-
Davis GE, Senger DR. Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res 2005; 97:1093-1107.
-
(2005)
Circ Res
, vol.97
, pp. 1093-1107
-
-
Davis, G.E.1
Senger, D.R.2
-
9
-
-
34250702237
-
Cell-matrix adhesion in vascular development
-
Hynes RO. Cell-matrix adhesion in vascular development. J Thromb Haemost 2007; 5 (Suppl 1):32-40.
-
(2007)
J Thromb Haemost
, vol.5
, Issue.SUPPL. 1
, pp. 32-40
-
-
Hynes, R.O.1
-
10
-
-
34247872986
-
The extracellular matrix and blood vessel formation: Not just a scaffold
-
Rhodes JM, Simons M. The extracellular matrix and blood vessel formation: not just a scaffold. J Cell Mol Med 2007; 11:176-205.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 176-205
-
-
Rhodes, J.M.1
Simons, M.2
-
11
-
-
34447550067
-
Laminin isoforms in development and disease
-
Scheele S, Nystrom A, Durbeej M, et al. Laminin isoforms in development and disease. J Mol Med 2007; 85:825-836.
-
(2007)
J Mol Med
, vol.85
, pp. 825-836
-
-
Scheele, S.1
Nystrom, A.2
Durbeej, M.3
-
12
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 2007; 8:464-478.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
13
-
-
35248893422
-
What tangled webs they weave: Rho-GTPase control of angiogenesis
-
Bryan BA, D'Amore PA. What tangled webs they weave: Rho-GTPase control of angiogenesis. Cell Mol Life Sci 2007; 64:2053-2065.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 2053-2065
-
-
Bryan, B.A.1
D'Amore, P.A.2
-
14
-
-
1242296871
-
Rho activity critically and selectively regulates endothelial cell organization during angiogenesis
-
Hoang MV, Whelan MC, Senger DR. Rho activity critically and selectively regulates endothelial cell organization during angiogenesis. Proc Natl Acad Sci U S A 2004; 101:1874-1879.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1874-1879
-
-
Hoang, M.V.1
Whelan, M.C.2
Senger, D.R.3
-
15
-
-
0029967619
-
An alpha 2 beta 1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix
-
Davis GE, Camarillo CW. An alpha 2 beta 1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix. Exp Cell Res 1996; 224:39-51.
-
(1996)
Exp Cell Res
, vol.224
, pp. 39-51
-
-
Davis, G.E.1
Camarillo, C.W.2
-
16
-
-
0037087648
-
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices
-
Bayless KJ, Davis GE. The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices. J Cell Sci 2002; 115:1123-1136.
-
(2002)
J Cell Sci
, vol.115
, pp. 1123-1136
-
-
Bayless, K.J.1
Davis, G.E.2
-
17
-
-
1542283690
-
Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cells
-
Liu Y, Senger DR. Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cells. Faseb J 2004; 18:457-468.
-
(2004)
Faseb J
, vol.18
, pp. 457-468
-
-
Liu, Y.1
Senger, D.R.2
-
18
-
-
38749151658
-
Cdc42 and Rac1-mediated endothelial lumen formation requires Pak2, Pak4, Par3, and Protein Kinase C-dependent signaling
-
Koh W, Mahan RD, Davis GE. Cdc42 and Rac1-mediated endothelial lumen formation requires Pak2, Pak4, Par3, and Protein Kinase C-dependent signaling. J Cell Sci 2008; 121:989-1001.
-
(2008)
J Cell Sci
, vol.121
, pp. 989-1001
-
-
Koh, W.1
Mahan, R.D.2
Davis, G.E.3
-
19
-
-
21244438355
-
Expression and function of laminins in the embryonic and mature vasculature
-
Hallmann R, Horn N, Selg M, et al. Expression and function of laminins in the embryonic and mature vasculature. Physiol Rev 2005; 85:979-1000.
-
(2005)
Physiol Rev
, vol.85
, pp. 979-1000
-
-
Hallmann, R.1
Horn, N.2
Selg, M.3
-
20
-
-
29144519398
-
Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation
-
Pollard SM, Parsons MJ, Kamei M, et al. Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation. Dev Biol 2006; 289:64-76.
-
(2006)
Dev Biol
, vol.289
, pp. 64-76
-
-
Pollard, S.M.1
Parsons, M.J.2
Kamei, M.3
-
21
-
-
43249122406
-
Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow
-
in press
-
Jakobsson L, Domogatskaya A, Tryggvason K, Edgar D, Claesson-Welsh L. Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow. Faseb J (in press).
-
Faseb J
-
-
Jakobsson, L.1
Domogatskaya, A.2
Tryggvason, K.3
Edgar, D.4
Claesson-Welsh, L.5
-
23
-
-
0036007196
-
Deletion of the laminin alpha4 chain leads to impaired microvessel maturation
-
Thyboll J, Kortesmaa J, Cao R, et al. Deletion of the laminin alpha4 chain leads to impaired microvessel maturation. Mol Cell Biol 2002; 22:1194-1202.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1194-1202
-
-
Thyboll, J.1
Kortesmaa, J.2
Cao, R.3
-
24
-
-
33749542764
-
Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3
-
Saunders WB, Bohnsack BL, Faske JB, et al. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol 2006; 175:179-191.
-
(2006)
J Cell Biol
, vol.175
, pp. 179-191
-
-
Saunders, W.B.1
Bohnsack, B.L.2
Faske, J.B.3
-
25
-
-
0035060384
-
Matrix metalloproteinase-1 and -9 activation by plasmin regulates a novel endothelial cell-mediated mechanism of collagen gel contraction and capillary tube regression in three-dimensional collagen matrices
-
Davis GE, Pintar Allen KA, Salazar R, Maxwell SA. Matrix metalloproteinase-1 and -9 activation by plasmin regulates a novel endothelial cell-mediated mechanism of collagen gel contraction and capillary tube regression in three-dimensional collagen matrices. J Cell Sci 2001; 114:917-930.
-
(2001)
J Cell Sci
, vol.114
, pp. 917-930
-
-
Davis, G.E.1
Pintar Allen, K.A.2
Salazar, R.3
Maxwell, S.A.4
-
26
-
-
34249744576
-
Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells
-
Yana I, Sagara H, Takaki S, et al. Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells. J Cell Sci 2007; 120:1607-1614.
-
(2007)
J Cell Sci
, vol.120
, pp. 1607-1614
-
-
Yana, I.1
Sagara, H.2
Takaki, S.3
-
27
-
-
9444274032
-
MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix
-
Chun TH, Sabeh F, Ota I, et al. MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix. J Cell Biol 2004; 167:757-767.
-
(2004)
J Cell Biol
, vol.167
, pp. 757-767
-
-
Chun, T.H.1
Sabeh, F.2
Ota, I.3
-
28
-
-
21044432369
-
MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices
-
Saunders WB, Bayless KJ, Davis GE. MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. J Cell Sci 2005; 118:2325-2340.
-
(2005)
J Cell Sci
, vol.118
, pp. 2325-2340
-
-
Saunders, W.B.1
Bayless, K.J.2
Davis, G.E.3
-
29
-
-
33746228132
-
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10
-
Chang S, Young BD, Li S, et al. Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 2006; 126:321-334.
-
(2006)
Cell
, vol.126
, pp. 321-334
-
-
Chang, S.1
Young, B.D.2
Li, S.3
-
32
-
-
34250671041
-
Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization
-
Ramsauer M, D'Amore PA. Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization. J Cell Sci 2007; 120:1810-1817.
-
(2007)
J Cell Sci
, vol.120
, pp. 1810-1817
-
-
Ramsauer, M.1
D'Amore, P.A.2
-
33
-
-
14844284571
-
TIMP-2: An endogenous inhibitor of angiogenesis
-
Stetler-Stevenson WG, Seo DW. TIMP-2: an endogenous inhibitor of angiogenesis. Trends Mol Med 2005; 11:97-103.
-
(2005)
Trends Mol Med
, vol.11
, pp. 97-103
-
-
Stetler-Stevenson, W.G.1
Seo, D.W.2
-
34
-
-
0042197340
-
TIMP-2 mediated inhibition of angiogenesis: An MMP-independent mechanism
-
Seo DW, Li H, Guedez L, et al. TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell 2003; 114:171-180.
-
(2003)
Cell
, vol.114
, pp. 171-180
-
-
Seo, D.W.1
Li, H.2
Guedez, L.3
-
35
-
-
0037393850
-
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
-
Qi JH, Ebrahem Q, Moore N, et al. A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med 2003; 9:407-415.
-
(2003)
Nat Med
, vol.9
, pp. 407-415
-
-
Qi, J.H.1
Ebrahem, Q.2
Moore, N.3
-
36
-
-
35748947260
-
Type IV collagen-derived angiogenesis inhibitors
-
Mundel TM, Kalluri R. Type IV collagen-derived angiogenesis inhibitors. Microvasc Res 2007; 74:85-89.
-
(2007)
Microvasc Res
, vol.74
, pp. 85-89
-
-
Mundel, T.M.1
Kalluri, R.2
-
37
-
-
34247856977
-
-
Folkman J. Tumor suppression by p53 is mediated in part by the antiangiogenic activity of endostatin and tumstatin. Sci STKE 2006, 2006:pe35.
-
Folkman J. Tumor suppression by p53 is mediated in part by the antiangiogenic activity of endostatin and tumstatin. Sci STKE 2006, 2006:pe35.
-
-
-
-
38
-
-
0033847622
-
Regulation of tissue injury responses by the exposure of matricryptic sites within extracellular matrix molecules
-
Davis GE, Bayless KJ, Davis MJ, Meininger GA. Regulation of tissue injury responses by the exposure of matricryptic sites within extracellular matrix molecules. Am J Pathol 2000; 156:1489-1498.
-
(2000)
Am J Pathol
, vol.156
, pp. 1489-1498
-
-
Davis, G.E.1
Bayless, K.J.2
Davis, M.J.3
Meininger, G.A.4
-
39
-
-
1642307340
-
Endostatin's antiangiogenic signaling network
-
Abdollahi A, Hahnfeldt P, Maercker C, et al. Endostatin's antiangiogenic signaling network. Mol Cell 2004; 13:649-663.
-
(2004)
Mol Cell
, vol.13
, pp. 649-663
-
-
Abdollahi, A.1
Hahnfeldt, P.2
Maercker, C.3
-
40
-
-
14644388846
-
Recombinant alpha2(IV)NC1 domain inhibits tumor cell-extracellular matrix interactions, induces cellular senescence, and inhibits tumor growth in vivo
-
Roth JM, Akalu A, Zelmanovich A, et al. Recombinant alpha2(IV)NC1 domain inhibits tumor cell-extracellular matrix interactions, induces cellular senescence, and inhibits tumor growth in vivo. Am J Pathol 2005; 166:901-911.
-
(2005)
Am J Pathol
, vol.166
, pp. 901-911
-
-
Roth, J.M.1
Akalu, A.2
Zelmanovich, A.3
-
41
-
-
3142736457
-
-
Bix G, Fu J, Gonzalez EM, et al. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol 2004; 166:97-109.
-
Bix G, Fu J, Gonzalez EM, et al. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol 2004; 166:97-109.
-
-
-
-
42
-
-
33751354608
-
Endorepellin in vivo: Targeting the tumor vasculature and retarding cancer growth and metabolism
-
Bix G, Castello R, Burrows M, et al. Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism. J Natl Cancer Inst 2006; 98:1634-1646.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1634-1646
-
-
Bix, G.1
Castello, R.2
Burrows, M.3
-
43
-
-
22344437713
-
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
-
Lee S, Jilani SM, Nikolova GV, et al. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J Cell Biol 2005; 169:681-691.
-
(2005)
J Cell Biol
, vol.169
, pp. 681-691
-
-
Lee, S.1
Jilani, S.M.2
Nikolova, G.V.3
-
44
-
-
33749441325
-
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
-
Mancuso MR, Davis R, Norberg SM, et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 2006; 116:2610-2621.
-
(2006)
J Clin Invest
, vol.116
, pp. 2610-2621
-
-
Mancuso, M.R.1
Davis, R.2
Norberg, S.M.3
-
45
-
-
24944556468
-
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1
-
Ridnour LA, Isenberg JS, Espey MG, et al. Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1. Proc Natl Acad Sci U S A 2005; 102:13147-13152.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13147-13152
-
-
Ridnour, L.A.1
Isenberg, J.S.2
Espey, M.G.3
-
46
-
-
33751582239
-
Thrombospondin-1 antagonizes nitric oxide-stimulated vascular smooth muscle cell responses
-
Isenberg JS, Wink DA, Roberts DD. Thrombospondin-1 antagonizes nitric oxide-stimulated vascular smooth muscle cell responses. Cardiovasc Res 2006; 71:785-793.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 785-793
-
-
Isenberg, J.S.1
Wink, D.A.2
Roberts, D.D.3
-
47
-
-
33748747969
-
CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1
-
Isenberg JS, Ridnour LA, Dimitry J, et al. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem 2006; 281:26069-26080.
-
(2006)
J Biol Chem
, vol.281
, pp. 26069-26080
-
-
Isenberg, J.S.1
Ridnour, L.A.2
Dimitry, J.3
-
48
-
-
36348989009
-
Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia
-
Isenberg JS, Hyodo F, Pappan LK, et al. Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia. Arterioscler Thromb Vasc Biol 2007; 27:2582-2588.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2582-2588
-
-
Isenberg, J.S.1
Hyodo, F.2
Pappan, L.K.3
-
49
-
-
85117738637
-
-
Isenberg JS, Romeo MJ, Yu C, et al. Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood 2008; 111:613-623. TSP-1 represents a major secreted product of platelets and this new study provides important new insight into why this is so. The ability of TSP-1 to interfere with nitric oxidemediated signaling allowsplatelets to acutely and locally antagonize nitric oxide mediated dilation and inhibitory effects on adhesion receptor function, thus, leading to increased platelet aggregation and prothrombotic activities.
-
Isenberg JS, Romeo MJ, Yu C, et al. Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood 2008; 111:613-623. TSP-1 represents a major secreted product of platelets and this new study provides important new insight into why this is so. The ability of TSP-1 to interfere with nitric oxidemediated signaling allowsplatelets to acutely and locally antagonize nitric oxide mediated dilation and inhibitory effects on adhesion receptor function, thus, leading to increased platelet aggregation and prothrombotic activities.
-
-
-
-
50
-
-
35548932510
-
Vascular remodeling of the mouse yolk sac requires hemodynamic force
-
Lucitti JL, Jones EA, Huang C, et al. Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development 2007; 134:3317-3326.
-
(2007)
Development
, vol.134
, pp. 3317-3326
-
-
Lucitti, J.L.1
Jones, E.A.2
Huang, C.3
-
51
-
-
0024557970
-
Microvascular rarefaction and tissue vascular resistance in hypertension
-
Greene AS, Tonellato PJ, Lui J, et al. Microvascular rarefaction and tissue vascular resistance in hypertension. Am J Physiol 1989; 256:H126-H131.
-
(1989)
Am J Physiol
, vol.256
-
-
Greene, A.S.1
Tonellato, P.J.2
Lui, J.3
-
52
-
-
37549059962
-
-
Isenberg JS, Pappan LK, Romeo MJ, et al. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts. Ann Surg 2008; 247:180-190. This is a very interesting study showing the powerful influence of TSP-1 signaling pathways on graft survival. This work has important implications for the response of tissues to ischemia and how vessels react to hypoxia stimuli and recover from these injuries.
-
Isenberg JS, Pappan LK, Romeo MJ, et al. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts. Ann Surg 2008; 247:180-190. This is a very interesting study showing the powerful influence of TSP-1 signaling pathways on graft survival. This work has important implications for the response of tissues to ischemia and how vessels react to hypoxia stimuli and recover from these injuries.
-
-
-
-
53
-
-
0034256024
-
Signaling networks linking integrins and rho family GTPases
-
Schwartz MA, Shattil SJ. Signaling networks linking integrins and rho family GTPases. Trends Biochem Sci 2000; 25:388-391.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 388-391
-
-
Schwartz, M.A.1
Shattil, S.J.2
-
54
-
-
30344460532
-
ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis
-
Mavria G, Vercoulen Y, Yeo M, et al. ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis. Cancer Cell 2006; 9:33-44.
-
(2006)
Cancer Cell
, vol.9
, pp. 33-44
-
-
Mavria, G.1
Vercoulen, Y.2
Yeo, M.3
-
55
-
-
1642564595
-
Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho
-
Bayless KJ, Davis GE. Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho. J Biol Chem 2004; 279:11686-11695.
-
(2004)
J Biol Chem
, vol.279
, pp. 11686-11695
-
-
Bayless, K.J.1
Davis, G.E.2
-
56
-
-
35748969104
-
Src family kinases promote vessel stability by antagonizing the Rho/ROCK pathway
-
This very nice study extends previouswork showing the involvement of ERK signaling in promoting vessel stability and identifies Src family kinases as also playing a key role in conjunction with ERK for inactivating Rho/Rho kinase tomaintain the integrity of the vascular wall
-
Im E, Kazlauskas A. Src family kinases promote vessel stability by antagonizing the Rho/ROCK pathway. J Biol Chem 2007; 282:29122-29129. This very nice study extends previouswork showing the involvement of ERK signaling in promoting vessel stability and identifies Src family kinases as also playing a key role in conjunction with ERK for inactivating Rho/Rho kinase tomaintain the integrity of the vascular wall.
-
(2007)
J Biol Chem
, vol.282
, pp. 29122-29129
-
-
Im, E.1
Kazlauskas, A.2
-
57
-
-
0033847194
-
RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins
-
Bayless KJ, Salazar R, Davis GE. RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins. Am J Pathol 2000; 156:1673-1683.
-
(2000)
Am J Pathol
, vol.156
, pp. 1673-1683
-
-
Bayless, K.J.1
Salazar, R.2
Davis, G.E.3
-
58
-
-
33846231363
-
Regulation of postangiogenic neovessel survival by beta1 and beta3 integrins in collagen and fibrin matrices
-
Carnevale E, Fogel E, Aplin AC, et al. Regulation of postangiogenic neovessel survival by beta1 and beta3 integrins in collagen and fibrin matrices. J Vasc Res 2007; 44:40-50.
-
(2007)
J Vasc Res
, vol.44
, pp. 40-50
-
-
Carnevale, E.1
Fogel, E.2
Aplin, A.C.3
-
59
-
-
33344461837
-
Integrins and angiogenesis: A sticky business
-
Serini G, Valdembri D, Bussolino F. Integrins and angiogenesis: a sticky business. Exp Cell Res 2006; 312:651-658.
-
(2006)
Exp Cell Res
, vol.312
, pp. 651-658
-
-
Serini, G.1
Valdembri, D.2
Bussolino, F.3
-
60
-
-
36749043327
-
Biochemistry and functional significance of collagen cross-linking
-
Robins SP. Biochemistry and functional significance of collagen cross-linking. Biochem Soc Trans 2007; 35:849-852.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 849-852
-
-
Robins, S.P.1
-
61
-
-
41349111883
-
-
Zhang Z, Ramirez NE, Yankeelov TE, et al. {alpha}2{beta}1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor-cell specific manner. Blood 2008; 111:1980-1988.
-
Zhang Z, Ramirez NE, Yankeelov TE, et al. {alpha}2{beta}1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor-cell specific manner. Blood 2008; 111:1980-1988.
-
-
-
-
62
-
-
33846242140
-
Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization
-
Zweers MC, Davidson JM, Pozzi A, et al. Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization. J Invest Dermatol 2007; 127:467-478.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 467-478
-
-
Zweers, M.C.1
Davidson, J.M.2
Pozzi, A.3
-
63
-
-
0033035808
-
Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis
-
Gardner H, Broberg A, Pozzi A, et al. Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis. J Cell Sci 1999; 112 (Pt 3):263-272.
-
(1999)
J Cell Sci
, vol.112
, Issue.PART 3
, pp. 263-272
-
-
Gardner, H.1
Broberg, A.2
Pozzi, A.3
-
64
-
-
0036142782
-
The alpha(1)beta(1) and alpha(2)-beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
-
Senger DR, Perruzzi CA, Streit M, et al. The alpha(1)beta(1) and alpha(2)-beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. Am J Pathol 2002; 160:195-204.
-
(2002)
Am J Pathol
, vol.160
, pp. 195-204
-
-
Senger, D.R.1
Perruzzi, C.A.2
Streit, M.3
-
65
-
-
0031459892
-
Angiogenesis promoted by vascular endothelial growth factor: Regulation through alpha1beta1 and alpha2beta1 integrins
-
Senger DR, Claffey KP, Benes JE, et al. Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins. Proc Natl Acad Sci U S A 1997; 94:13612-13617.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13612-13617
-
-
Senger, D.R.1
Claffey, K.P.2
Benes, J.E.3
-
66
-
-
0035983579
-
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies
-
Francis SE, Goh KL, Hodivala-Dilke K, et al. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler Thromb Vasc Biol 2002; 22:927-933.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 927-933
-
-
Francis, S.E.1
Goh, K.L.2
Hodivala-Dilke, K.3
-
67
-
-
20444483652
-
Integrin alpha4beta1-VCAM-1- mediated adhesion between endothelial and mural cells is required for blood vessel maturation
-
Garmy-Susini B, Jin H, Zhu Y, et al. Integrin alpha4beta1-VCAM-1- mediated adhesion between endothelial and mural cells is required for blood vessel maturation. J Clin Invest 2005; 115:1542-1551.
-
(2005)
J Clin Invest
, vol.115
, pp. 1542-1551
-
-
Garmy-Susini, B.1
Jin, H.2
Zhu, Y.3
-
68
-
-
34247198981
-
Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades
-
Mishima K, Watabe T, Saito A, et al. Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell 2007; 18:1421-1429.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1421-1429
-
-
Mishima, K.1
Watabe, T.2
Saito, A.3
-
69
-
-
35348890874
-
-
Astrof S, Crowley D, Hynes RO. Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Dev Biol 2007; 311:11-24. This is an important new study which begins to characterize the unique nature of the embryonic ECM environment and identifies requirements for fibronectin during cardiovascular development. It also implicates an important and required role for fibronectins in early vascular assembly, perivascular cell recruitment as well as vascular remodeling events. This type of work will lead to new insights into how the unique signals delivered from embryonic matrices control vascular development and how this ultimately will be distinct or show similarities in the context of various disease states.
-
Astrof S, Crowley D, Hynes RO. Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Dev Biol 2007; 311:11-24. This is an important new study which begins to characterize the unique nature of the embryonic ECM environment and identifies requirements for fibronectin during cardiovascular development. It also implicates an important and required role for fibronectins in early vascular assembly, perivascular cell recruitment as well as vascular remodeling events. This type of work will lead to new insights into how the unique signals delivered from embryonic matrices control vascular development and how this ultimately will be distinct or show similarities in the context of various disease states.
-
-
-
-
70
-
-
3042697038
-
Hyaluronan: From extracellular glue to pericellular cue
-
Toole BP. Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer 2004; 4:528-539.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 528-539
-
-
Toole, B.P.1
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