Tissue factor: A mini-review

Journal of Tissue Engineering and Regenerative Medicine

Volumn 1, Issue 3, 2007, Pages 161-169

  Daubie, Valéry ^a   Pochet, Roland ^a   Houard, Sophie ^b   Philippart, Pierre ^c  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Henogen   (Belgium)

^c IRIS   (Belgium)

Author keywords

Review; Tissue factor; Tissue factor expression; Tissue factor signalling; Tissue factor structure

Indexed keywords

CELL PROLIFERATION; PROTEINS; TISSUE; TRANSCRIPTION;

FACTOR STRUCTURE; INTEGRAL MEMBRANE; TERNARY COMPLEX; TISSUE FACTOR EXPRESSION; TISSUE FACTOR SIGNALING; TISSUE FACTOR STRUCTURE; TISSUE FACTORS;

GLYCOPROTEINS;

CELL SURFACE RECEPTOR; THROMBOPLASTIN;

ANIMAL; CHEMISTRY; GENETICS; HUMAN; METABOLISM; ORAL SURGERY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HUMANS; ORAL SURGICAL PROCEDURES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; THROMBOPLASTIN;

EID: 41949088161     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.9     Document Type: Review

References (105)

1. Abe K, Shoji M, Chen J, et al. 1999; Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor. Proc Natl Acad Sci USA 96: 8663-8668.
2. Ahamed J, Belting M, Ruf W. 2005; Regulation of tissue factorinduced signalling by endogenous and recombinant tissue factor pathway inhibitor 1. Blood 105: 2384-2391.
3. Bach R, Konigsberg WH, Nemerson Y. 1988; Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half cysteine. Biochemistry, 27: 4227-4231.
4. Bachli E. 2000; History of tissue factor. Br J Haematol 110: 248-255.
5. Bachli EB, Pech CM, Johnson KM, et al. 2003; Factor X and thrombin, but not factor VIIa, elicit specific cellular responses in dermal fibroblasts. J Thromb Haemost 1: 1935-1944.
6. Belting M, Dorrell M, Sandgren S, et al. 2004; Regulation of angiogenesis by tissue factor cytoplasmic domain signalling. Nat Med 10: 502-509.
7. Berckmans RJ, Neiuwland R, Boing AN, et al. 2001; Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb Haemost 85: 639-646.
8. Bogdanov VY, Balasubramanian V, Hathcock J, et al. 2003; Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med 9: 458-462.
9. Bogdanov VY, Kirk RI, Miller C, et al. 2006; Identification and characterization of murine alternatively spliced tissue factor. J Thromb Haemost 4: 158-167.
10. Bouchard BA, Shatos MA, Tracy PB. 1997; Human brain pericytes differentially regulate expression of procoagulant enzyme complexes comprising the extrinsic pathway of blood coagulation. Arterioscler Thromb Vasc Biol 17: 1-9.
11. Breimo ES, Osterud B. 2005; Generation of tissue factor-rich microparticles in an ex vivo whole blood model. Blood Coagul Fibrinolysis 16: 399-405.
12. Boys CW, Miller A, Harlos K, et al. 1993; Crystallization and preliminary X-ray analysis of human tissue factor extracellular domain. J Mol Biol 234: 1263-1265.
13. Broze GJ, Leykam JE, Schwartz BD, Miletich JP. 1985; Purification of human brain tissue factor. J Biol Chem 260: 10917-10920.
14. Butenas S, Bouchard BA, Brummel-Ziedins KE, Parhami-Seren B, Mann KG. 2005; Tissue factor activity in whole blood. Blood 25: 2764-2770.
15. Camerer E, Rottingen JA, Gjernes E, et al. 1999; Coagulation factors VIIa and Xa induce cell signalling leading to the upregulation of the egr-1 gene. J Biol Chem 274: 32225-32233.
16. Camerer E, Huang W, Coughlin SR. 2000; Tissue factor and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci USA 97: 5255-5260.
17. Chen J, Bierhaus A, Schiekofer S, et al. 2001; Tissue factor - a receptor involved in the control of cellular properties, including angiogenesis. Thromb Haemost 86: 334-345.
18. Chou J, Mackman N, Merrill-Skoloff G, et al. 2004; Haematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood 104: 3190-3197.
19. Chouhan VD, De La Cadena RA, Nagaswami C, et al. 1997; Simultaneous occurrence of human antibodies directed against fibrinogen, thrombin, and factor V following exposure to bovine thrombin: effects on blood coagulation, protein C activation and platelet function. Thromb Haemost 77: 343-349.
20. Christie RJ, Carrington L, Alving B. 1997; Postoperative bleeding induced by topical bovine thrombin: report of two cases. Surgery 121: 708-710.
21. Cirillo P, Golino P, Calabro P, et al. 2005; C-reactive protein induces tissue factor expression and promotes smooth muscle cell and endothelial cell proliferation. Cardiovasc Res 68: 47-55.
22. Coughlin SR. 2000; Thrombin signalling and protease-activated receptors. Nature 407: 258-264.
23. Cunningham MA, Romas P, Hutchinson P, Holdsworth SR, Tipping PG. 1999; Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects inmacrophages. Blood 94: 3413-3420.
24. Daubie V, Cauwenberghs S, Senden N, et al. 2006; Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation. Biochim Biophys Acta 1763: 860-869.
25. Dorfleutner A, Ruf W. 2003; Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. Blood 102: 3998-4005.
26. Drake TA, Morrissey JH, Edgington TS. 1989; Selective cellular expression of tissue factor in human tissues. Am J Pathol 134: 1087-1097.
27. Eddleston M, de la Torre JC, Oldstone MB, et al. 1993; Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis. J Clin Invest 92: 349-358.
28. Eto M, Kouroedov A, Cosentino F, Luscher TF. 2005; Glycogen synthase kinase-3 mediates endothelial cell activation by tumour necrosis factor-alpha. Circulation 112: 1316-1322.
29. Faulk WP, Labarrer CA, Carson SD. 1990; Tissue factor: identification and characterization of cell types in human placentae. Blood 76: 86-96.
30. Fisher KL, Gorman CM, Vehar GA, O'Brien DP, Lawn RM. 1987; Cloning and expression of human tissue factor cDNA. Thromb Res 48: 89-99.
31. Fleck RA, Rao LV, Rapaport SI, Varki N. 1990; Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res 59: 421-437.
32. Flossel C, Luther T, Muller M, Albrecht S, Kasper M. 1994; Immunohistochemical detection of tissue factor (TF) on paraffin sections of routinely fixed human tissue. Histochemistry 101: 449-453.
33. Fu M, Zhu X, Zhang J, et al. 2003; Egr-1 target genes in human endothelial cells identified by microarray analysis. Gene 315: 33-41.
34. Giesen PL, Rauch U, Bohrmann B, et al. 1999; Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci USA 96: 2311-2315.
35. Gross PL, Furie BC, Merrill-Skoloff G, Chou J, Furie B. 2005; Leukocyte versus microparticle-mediated tissue factor transfer during arteriolar thrombus development. J Leukoc Biol 78: 1318-1326.
36. Guha A, Bach R, Konigsberg W, Nemerson Y. 1986; Affinity purification of human tissue factor: interaction of factor VII and tissue factor in detergent micelles. Proc Natl Acad Sci USA 83: 299-302.
37. Halvorsen H, Osterud B. 1991; Cellular interactions in lipopolysaccharide-induced tissue factor activity in monocytes: the mandatory role of cathepsin G. Thromb Haemost 65: 701 (Abstr 166).
38. Halvorsen H, Olsen JO, Osterud B. 1993; Granulocytes enhance LPSinduced tissue factor activity in monocytes via an interaction with platelets. J Leukoc Biol 54: 275-282.
39. Harlos K, Martin DM, O'Brien DP, et al. 1994; Crystal structure of the extracellular region of human tissue factor. Nature 370: 662-666.
40. Hartzell S, Ryder K, Lanahan A, Lau LF, Nathan D. 1989; A growth factor-responsive gene of murine BALB/c3T3 cells encodes a protein homologous to human tissue factor. Mol Cell Biol 9: 2567-2573.
41. Hattori T, Khan MM, Colman RW, Edmunds LH Jr. 2005; Plasma tissue factor plus activated mononuclear cells activate factors VII and X in cardiac surgical wounds. J Am Coll Cardiol 46: 707-713.
42. Hembrough TA, Swartz GM, Papathanassiu A, et al. 2003; Tissue factor/factor VIIa inhibitors block angiogenesis and tumour growth through a nonhemostatic mechanism. Cancer Res 63: 2997-3000.
43. Hjortoe GM, Petersen LC, Albrektsen T, et al. 2004; Tissue factorfactor VIIa-specific upregulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood 103: 3029-3037.
44. Kagawa H, Komiyama Y, Nakamura S, et al. 1998; Expression of functional tissue factor on small vesicles of lipopolysaccharidestimulated human vascular endothelial cells. Thromb Res 91: 297-304.
45. Kelley RF, Costas KE, O'Connell MP, Lazarus RA. 1995; Analysis of the factor VIIa binding site on human tissue factor: effects of tissue factor mutations on the kinetics and thermodynamics of binding. Biochemistry 34: 10383-10392.
46. Key NS, Bach RR. 2001; Tissue factor as a therapeutic target. Thromb Haemost 85: 375-376.
47. Khan MM, Hattori T, Niewiarowski S, Edmunds LH Jr, Colman RW. 2006; Truncated and microparticle-free soluble tissue factor bound to peripheral monocytes preferentially activate factor VII. Thromb Haemost 95: 462-468.
48. Koizume S, Jim MS, Miyagi E, et al. 2006; Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII. Cancer Res 66: 9453-9460.
49. Kushak RI, Nestoridi E, Lambert J, et al. 2005; Detached endothelial cells and microparticles as sources of tissue factor activity. Thromb Res 116: 409-419.
50. Lupu C, Westmuckett AD, Peer G, et al. 2005; Tissue factordependent coagulation is preferentially upregulated within arterial branching areas in a baboon model of Escherichia coli sepsis. Am J Pathol 167: 1161-1172.
51. Losche W. 2005; Platelets and tissue factor. Platelets 16: 313-319.
52. Macfarlane RG. 1972; The theory of blood coagulation. In Human Blood Coagulation, Haemostasis and Thrombosis, Biggs R (ed.). Blackwell Scientific: Oxford; 1-31.
53. Mackman N, Sawdey MS, Keeton MR, Loskutoff DJ. 1993; Murine tissue factor gene expression in vivo. Tissue and cell specificity and regulation by lipopolysaccharide. Am J Pathol 143: 76-84.
54. Marutsuka K, Hatakeyama K, Sato Y, et al. 2002; Protease-activated receptor 2 (PAR2) mediates vascular smoothmuscle cell migration induced by tissue factor/factor VIIa complex. Thromb Res 107: 271-276.
55. Mechtcheriakova D, Wlachos A, Holzmuller H, Binder BR, Hofer E. 1999; Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1. Blood 93: 3811-3823.
56. Miller DL, Yaron R, Yellin J. 1998; CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression. J Leukoc Biol 63: 373-379.
57. Mody RS, Carson SD. 1997; Tissue factor cytoplasmic domain peptide is multiply phosphorylated in vitro. Biochemistry 36: 7869-7875.
58. Morris DR, Ding Y, Ricks TK, et al. 2006; Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signalling, migration, and invasion of breast cancer cells. Cancer Res 66: 307-314.
59. Morrissey JH, Fakhrai H, Edgington TS. 1987; Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade. Cell 50: 129-135.
60. Morrissey JH. 2001; Tissue factor: an enzyme cofactor and a true receptor. Thromb Haemost 86: 66-74.
61. Mulder AB, Smit JW, Bom VJ, et al. 1996; Association of smooth muscle cell tissue factor with caveolae. Blood 88: 1306-1313.
62. Muller YA, Ultsh MH, Kelley RF, de Vos AM. 1994; Structure of the extracellular domain of human tissue factor: location of the factor VIIa binding site. Biochemistry 33: 10864-10870.
63. oA resolution. J Mol Biol 256: 144-159.
64. Muller I, Klocke A, Alex M, et al. 2003; Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets. FASEB J 17: 476-478.
65. Muth H, Kreis I, Zimmermann R, Tillmanns H, Holschermann H. 2005; Differential gene expression in activated monocyte-derived macrophages following binding of factor VIIa to tissue factor. Thromb Haemost 94: 1028-1034.
66. Ollivier V, Chabbat J, Herbert JM, Hakim J, de Prost D. 2000; Vascular endothelial growth factor production by fibroblasts in response to factor VIIa binding to tissue factor involves thrombin and factor Xa. Arterioscler Thromb Vasc Biol 20: 1374-1381.
67. Osterud B. 1992; Platelet activating factor enhancement of lipopolysaccharide-induced tissue factor activity in monocytes: requirement of platelets and granulocytes. J Leukoc Biol 51: 462-465.
68. Osterud B. 2001; The role of platelets in decrypting monocyte tissue factor. Semin Hematol 38: 2-5.
69. Osterud B. 2003; The role of platelets in decrypting monocytes tissue factor. Dis Mon 49: 7-13.
70. Ott I, Weigand B, Michl R, et al. 2005; Tissue factor cytoplasmic domain stimulates migration by activation of the GTPase Rac1 and mitogen-activated protein kinase p38. Circulation 111: 349-355.
71. Pendurthi UR, Alok D, Rao LV. 1997; Binding of factor VIIa to tissue factor induces alterations in gene expression in humans fibroblasts cells: upregulation of poly(A) polymerase. Proc Natl Acad Sci USA 94: 12598-12603.
72. Philippart P, Brasseur M, Hoyaux D, Pochet R. 2003; Human recombinant tissue factor, platelet-rich plasma, and tetracycline induce a high-quality human bone graft: a 5-year survey. Int J Oral Maxillofac Implants 18: 411-416.
73. Philippart P, Daubie V, Pochet R. 2005; Sinus grafting using recombinant human tissue factor, platelet-rich plasma gel, autologous bone, and an organic bovine bone mineral xenograft: histologic analysis and case reports. Int J Oral Maxillofac Implants 20: 274-281.
74. Rapaport SI, Zivelin A, Minow RA, Hunter CS, Donnelly K. 1992; Clinical significance of antibodies to bovine and human thrombin and factor V after surgical use of bovine thrombin. Am J Clin Pathol 97: 84-91.
75. Rehemtulla A, Ruf W, Edgington TS. 1991; The integrity of the cysteine 186-cysteine 209 bond of the second disulphide loop of tissue factor is required for binding of factor VII.J Biol Chem 266: 10294-10299.
76. Riewald M, Ruf W. 2001; Mechanistic coupling of protease signalling and initiation of coagulation by tissue factor. Proc Natl Acad Sci USA 98: 7742-7747.
77. Roche N, Stirling RG, Lim S, et al. 2003; Effect of acute and chronic inflammatory stimuli on expression of protease-activated receptor 1 and 2 in alveolar macrophages. J Allergy Clin Immunol 111: 367-373.
78. Sato Y, Asada Y, Marutsuka K, Hatakeyama K, Sumiyoshi A. 1996; Tissue factor induces migration of cultured aortic smooth muscle cells. Thromb Haemost 75: 389-392.
79. Scarpati EM, Wen D, Broze GJ, et al. 1987; Human tissue factor: cDNA sequence and chromosome localization of the gene. Biochemistry 26: 5234-5238.
80. Schwertz H, Tolley ND, Foulks JM, et al. 2006; Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. J Exp Med 203: 2433-2440.
81. Sethi AS, Less DM, Douthwaite JA, Corder R. 2005; Factor VIIa stimulates endothelin-1 synthesis in TNF-primed endothelial cells by activation of protease-activated receptor 2. Clin Sci (Lond) 108: 255-263.
82. Shet AS, ArasO, Gupta K, et al. 2003; Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood 102: 2678-2683.
83. Siegbahn A, Johnell M, Rorsman C, et al. 2000; Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis. Blood 96: 3452-3458.
84. Sorensen BB, Rao LV, Tornehave D, Gammeltoft S, Petersen LC. 2003; Antiapoptotic effect of coagulation factor VIIa. Blood 102: 1708-1715.
85. Spicer EK, Horton R, BloemL, et al. 1987; Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA. Proc Natl Acad Sci USA 84: 5148-5152.
86. Stampfuss JJ, Censarek P, Fischer JW, Schror K, Webber AA. 2006; Rapid release of active tissue factor from human arterial smooth muscle cells under flow conditions. Arteriscler Thromb Vasc Biol 26: 1184.
87. Steffel J, Akhmedov A, Greutert H, Luscher TF, Tanner FC. 2005; Histamine induces tissue factor expression: implications for acute coronary syndromes. Circulation 112: 341-349.
88. Stone MJ, Ruf W, Miles DJ, Edgington TS, Wright PE. 1995; Recombinant soluble human tissue factor secreted by Saccharomyces cerevisiae and refolded from Escherichia coli inclusion bodies: glycosylation of mutants, activity and physical characterization. Biochem J 310: 605-614.
89. Szotowski B, Goldin-Lang P, Antoniak S, et al. 2005a; Alterations in myocardial tissue factor expression and cellular localization in dilated cardiomyopathy. J Am Coll Cardiol 45: 1081-1089.
90. Szotowski B, Antoniak S, Poller W, Schulteiss HP, Rauch U. 2005b; Procoagulant soluble tissue factor is released fromendothelial cells in response to inflammatory cytokines. Circ Res 96: 1233-1239.
91. Terry CM, Callahan KS. 1996; Protein kinase C regulates cytokineinduced tissue factor transcription and procoagulant activity in human endothelial cells. J Lab Clin Med 127: 81-93.
92. Versteeg HH, Hoedemaeker I, Diks SH, et al. 2000; Factor VIIa/tissue factor-induced signalling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac. J Biol Chem 275: 28750-28756.
93. Versteeg HH, Sorensen BB, Slofstra SH, et al. 2002; VIIa/tissue factor interaction results in a tissue factor cytoplasmic domainindependent activation of protein synthesis, p70, and P90 S6 kinase phosphorylation. J Biol Chem 277: 27065-27072.
94. Versteeg HH, Peppelenbosch MP, Spek CA. 2003; Tissue factor signal transduction in angiogenesis. Carcinogenesis 24: 1009-1013.
95. Versteeg HH, Spek CA, Richel DJ, Peppelebosch MP. 2004a; Coagulation factors VIIa and Xa inhibit apoptosis and anoikis. Oncogene 23: 410-417.
96. Versteeg HH, Spek CA, Slofstra SH, et al. 2004b; FVIIa: TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production. Circ Res 94: 1032-1040.
97. Versteeg HH, Ruf W. 2006; Emerging insights in tissue factor dependent signalling events. Semin Thromb Hemost 32: 24-32.
98. Wang X, Gjernes E, Prydz H. 2002; Factor VIIa induces tissue factor-dependent upregulation of interleukin-8 of in a human keratinocyte line. J Biol Chem 277: 23620-23626.
99. Watanabe T, Yasuda M, Yamamoto T. 1999; Angiogenesis induced by tissue factor in vitro and in vivo. Thromb Res 96: 183-189.
100. Wilcox JN, Smith KM, Schwartz SM, Gordon D. 1989; Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 86: 2839-2843.
101. Wu SQ, Aird WC. 2005; Thrombin, TNF-α, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular muscle cells. Am J Physiol Heart Circ Physiol 289: H873-885.
102. Yu JL, Rak JW. 2004; Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells. J Thromb Haemost 2: 2065-2067.
103. Zehnder JL, Leung LL. 1990; Development of antibodies to thrombin and factor V with recurrent bleeding in a patient exposed to topical bovine thrombin. Blood 76: 2011-2016.
104. Zillmann A, Luther T, Muller I, et al. 2001; Platelet-associated tissue factor contributes to the collagen-triggered activation of blood coagulation. Biochem Biophys Res Commun 281: 603-609.
105. Zioncheck TF, Roy S, Vehar GA. 1992; The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism. J Biol Chem 267: 3561-3564.