Estradiol-17Β protects against hypoxia-induced hepatocyte injury through ER-mediated upregulation of Bcl-2 as well as ER-independent antioxidant effects

Cell Research

Volumn 18, Issue 4, 2008, Pages 491-499

  Lee, Min Young ^a   Jung, Sun Chul ^a   Lee, Jang Hern ^b   Han, Ho Jae ^a  

^a Chonnam National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Chicken hepatocytes; Estradiol 17 ; Hypoxia

Indexed keywords

ANTIOXIDANT; ESTRADIOL; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL HYPOXIA; CELL PROTECTION; CHICKEN; DNA FRAGMENTATION; DRUG EFFECT; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; LIVER CELL; MALE; METABOLISM; PATHOLOGY; TIME; UPREGULATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; CELLS, CULTURED; CHICKENS; CYTOPROTECTION; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ESTRADIOL; HEPATOCYTES; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS; UP-REGULATION;

EID: 41849146425     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2008.42     Document Type: Article

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