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Guarantor of the article: Ian L. P. Beales, M.D. Specific author contributions: Both authors jointly conceived and performed the study, analyzed the data, and wrote the draft and final versions of the manuscript. Financial support: This work was supported by the Norfolk and Norwich University Hospital Bicentenary Trust in the form of a research studentship to Olorunseun O. Ogunwobi. Further research funding was received from The Royal Society, Peel Medical Research Trust, Mason Medical Research Foundation, Big C charity, and National Health Service (NHS) Research and Development funding (to Ian L. P. Beales), and the Institute of Biomedical Science (to Olorunseun O. Ogunwobi and Ian L. P. Beales). The design, performance, and analyses of the data were performed by the authors independently of any funding. Potential competing interests: None.
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