Acid increases proliferation via ERK and p38 MAPK-mediated increases in cyclooxygenase-2 in Barrett's adenocarcinoma cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 4 50-4, 2004, Pages

  Souza, Rhonda F ^a,b,d   Shewmake, Kenneth ^a   Pearson, Stephanie ^a   Sarosi Jr , George A ^a   Feagins, Linda A ^a   Ramirez, Ruben D ^a,c   Terada, Lance S ^a   Spechler, Stuart J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

Barrett's esophagus; Cell viability; Messenger ribonucleic acid stability

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACID; CYCLOOXYGENASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38;

ADENOCARCINOMA; ARTICLE; BARRETT ESOPHAGUS; CANCER CELL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; EXPOSURE; HUMAN; HUMAN CELL; METAPLASIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA STABILITY;

ACIDS; ADENOCARCINOMA; APOPTOSIS; BARRETT ESOPHAGUS; CELL DIVISION; CELL SURVIVAL; CYCLOOXYGENASE 2; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 4644360369     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00144.2004     Document Type: Article

References (27)

1. Aggarwal S, Taneja N, Lin L, Orringer MB, Rehemtulla A, and Beer DG. Indomethacin-induced apoptosis in esophageal adenocarcinoma cells involves upregulation of Bax and translocation of mitochondrial cytochrome c independent of COX-2 expression. Neoplasia 2: 346-356, 2000.
2. Buttar NS, Wang KK, Leontovich O, Westcott JY, Pacifico RJ, Anderson MA, Krishnadath KK, Lutzke LS, and Burgart LJ. Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus. Gastroenterology 122: 1101-1112, 2002.
3. Cryer B and Feldman M. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs. Am J Med 104: 413-421, 1998.
4. Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S, and DuBois RN. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107: 1183-1188, 1994.
5. Ginzinger DG. Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream. Exp Hematol 30: 503-512, 2002.
6. Inoue H, Yokoyama C, Hara S, Tone Y, and Tanabe T. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J Biol Chem 270: 24965-24971, 1995.
7. Kandil HM, Tanner G, Smalley W, Halter S, Radhika A, and DuBois RN. Cyclooxygenase-2 expression in Barrett's esophagus. Dig Dis Sci 46: 785-789, 2001.
8. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486, 1995.
9. Kaur BS, Khamnehei N, Iravani M, Namburu SS, Lin O, and Triadafilopoulos G. Rofecoxib inhibits cyclooxygenase 2 expression and activity and reduces cell proliferation in Barrett's esophagus. Gastroenterology 123: 60-67, 2002.
10. Lagergren J, Bergstrom R, Lindgren A, and Nyren O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 340: 825-831, 1999.
11. Matsuura H, Sakaue M, Subbaramaiah K, Kamitani H, Eling TE, Dannenberg AJ, Tanabe T, Inoue H, Arata J, and Jetten AM. Regulation of cyclooxygenase-2 by interferon-γ and transforming growth factor-α in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases. J Biol Chem 274: 29138-29148, 1999.
12. Moon Y and Pestka JJ. Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. Toxicol Sci 69: 373-382, 2002.
13. Ristimaki A, Honkanen N, Jankala H, Sipponen P, and Harkonen M. Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res 57: 1276-1280, 1997.
14. Saha D, Datta PK, Sheng H, Morrow JD, Wada M, Moses HL, and Beauchamp RD. Synergistic induction of cyclooxygenase-2 by transforming growth factor-β1 and epidermal growth factor inhibits apoptosis in epithelial cells. Neoplasia 1: 508-517, 1999.
15. Shirvani VN, Ouatu-Lascar R, Kaur BS, Omary MB, and Triadafilopoulos G. Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: ex vivo induction by bile salts and acid exposure. Gastroenterology 118: 487-496, 2000.
16. Soldes OS, Kuick RD, Thompson IA, Hughes SJ, Orringer MB, Iannettoni MD, Hanash SM, and Beer DG. Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas. Br J Cancer 79: 595-603, 1999.
17. Souza RF, Shewmake K, Beer DG, Cryer B, and Spechler SJ. Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. Cancer Res 60: 5767-5772, 2000.
18. Souza RF, Shewmake K, Terada LS, and Spechler SJ. Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagus. Gastroenterology 122: 299-307, 2002.
19. Steinbach G, Lynch PM, Phillips RK, Wallace MH, Hawk E, Gordon GB, Wakabayashi N, Saunders B, Shen Y, Fujimura T, Su LK, Levin B, Godio L, Patterson S, Rodriguez-Bigas MA, Jester SL, King KL, Schumacher M, Abbruzzese J, DuBois RN, Hittelman WN, Zimmerman S, Sherman JW, and Kelloff G. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 342: 1946-1952, 2000.
20. Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H, Jang M, Pezzuto JM, and Dannenberg AJ. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 273: 21875-21882, 1998.
21. Tsujii M and DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83: 493-501, 1995.
22. Tsujii M, Kawano S, and DuBois RN. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 94: 3336-3340, 1997.
23. Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, and DuBois RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93: 705-716, 1998.
24. Tucker ON, Dannenberg AJ, Yang EK, Zhang F, Teng L, Daly JM, Soslow RA, Masferrer JL, Woerner BM, Koki AT, and Fahey TJ. Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res 59: 987-990, 1999.
25. Williams C, Luongo C, Radhika A, Zhang T, Lamps LW, Nanney LB, Beauchamp RD, and DuBois RN. Elevated cyclooxygenase-2 levels in Min mous adenomas. Gastroenterology 111: 1134-1140, 1996.
26. Wilson KT, Fu S, Ramanujam KS, and Meltzer SJ. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res 58: 2929-2934, 1998.
27. Zhang Z, Sheng H, Shao J, Beauchamp RD, and DuBois RN. Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells. Neoplasia 2: 523-530, 2000.