Inhibition of Ras farnesylation by lovastatin leads to downregulation of proliferation and migration in primary cultured human glioblastoma cells

Anticancer Research

Volumn 20, Issue 4, 2000, Pages 2761-2771

  Bouterfa, Hakim L ^a,b   Sattelmeyer, Vera ^a   Czub, Stefanie ^a   Vordermark, Dirk ^a   Roosen, Klaus ^a   Tonn, Jörg Christian ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Novartis Pharma GmbH   (Germany)

Author keywords

Lovastatin glioma Ras farnesylation proliferation migration

Indexed keywords

MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE; PHALLOIDIN; RAS PROTEIN;

ACTIN FILAMENT; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; NICK END LABELING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BRAIN; CELL DIVISION; CELL MOVEMENT; DOWN-REGULATION; GLIOBLASTOMA; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; PROTEIN ISOPRENYLATION; RAS PROTEINS; RATS; TUMOR CELLS, CULTURED;

EID: 0033868493     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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