Overexpression of Bcl-2 as a proxy redox stimulus to enhance activity of non-viral redox-responsive delivery vectors

Biomaterials

Volumn 29, Issue 17, 2008, Pages 2680-2688

  Manickam, Devika S ^a   Hirata, Aiko ^a   Putt, David A ^b   Lash, Lawrence H ^b   Hirata, Fusao ^a   Oupický, David ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bcl 2 overexpression; Glutathione; Non viral gene delivery; Polyplexes; Transfection

Indexed keywords

NUCLEIC ACIDS; NUCLEOTIDES; POLYPEPTIDES; REDOX REACTIONS; RNA; TUMORS;

BCL-2 OVEREXPRESSION; GLUTATHIONE; NON-VIRAL GENE DELIVERY; POLYPLEXES;

GENE EXPRESSION;

ANTISENSE OLIGODEOXYNUCLEOTIDE; GLUTATHIONE; MESSENGER RNA; NUCLEIC ACID; PLASMID DNA; POLYELECTROLYTE; PROTEIN BCL 2; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; WESTERN BLOTTING;

BREAST NEOPLASMS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CLONE CELLS; CULTURE MEDIA, SERUM-FREE; DNA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; GENES, BCL-2; GENETIC VECTORS; GLUTATHIONE; HUMANS; OLIGONUCLEOTIDES, ANTISENSE; OXIDATION-REDUCTION; PLASMIDS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 41849101586     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.03.009     Document Type: Article

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