Focal adhesion kinase signaling controls cyclic tensile strain enhanced collagen I-induced osteogenic differentiation of human mesenchymal stem cells

MCB Molecular and Cellular Biomechanics

Volumn 4, Issue 4, 2007, Pages 177-188

  Ward Jr , Donald F ^a   Williams, William A ^a   Schapiro, Nicole E ^a   Christy, Samuel R ^a   Weber, Genevieve L ^a   Salt, Megan ^a   Klees, Robert F ^a   Boskey, Adele ^b   Plopper, George E ^a,c  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b HOSPITAL FOR SPECIAL SURGERY   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Collagen I ECM; FAK; Gene expression; hMSC; Mineralization; Osteogenesis; Point mutagenesis; Tensile strain

Indexed keywords

BIOMINERALIZATION; COLLAGEN; GENES; PHOSPHORYLATION; TENSILE STRAIN;

FOCAL ADHESION KINASE; OSTEOGENIC DIFFERENTIATION; POINT MUTAGENESIS; STEM CELLS;

BIOMEDICAL ENGINEERING;

BONE SIALOPROTEIN; COLLAGEN TYPE 1; EPITOPE; FOCAL ADHESION KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; MYC PROTEIN, HUMAN; OSTEOCALCIN; PTK2B PROTEIN, HUMAN; SIALOGLYCOPROTEIN; SP7 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; HUMAN; IMMUNOLOGY; MECHANOTRANSDUCTION; MESENCHYMAL STEM CELL; METABOLISM; PHOSPHORYLATION; POINT MUTATION; RETROVIRUS; TENSILE STRENGTH;

CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; COLLAGEN TYPE I; EPITOPES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FOCAL ADHESION KINASE 2; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MESENCHYMAL STEM CELLS; OSTEOCALCIN; OSTEOGENESIS; PHOSPHORYLATION; POINT MUTATION; PROTO-ONCOGENE PROTEINS C-MYC; RETROVIRIDAE; SIALOGLYCOPROTEINS; TENSILE STRENGTH; TRANSCRIPTION FACTORS;

EID: 41849098553     PISSN: 15565297     EISSN: 15565300     Source Type: Journal    
DOI: None     Document Type: Article

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