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Volumn 51, Issue 5, 2008, Pages 862-871

Effects of glucose tolerance on the changes provoked by glucose ingestion in microvascular function

Author keywords

Endothelium; Glucose intolerance; Hyperglycaemia; Hyperinsulinaemia; Microcirculation; Nitric oxide; Oxidative stress; Resistance arteries; Type 2 diabetes; Vascular function

Indexed keywords

ACETYLCHOLINE; ANTIOXIDANT; BIOLOGICAL MARKER; DIPYRONE; GLUCOSE;

EID: 41849098424     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-0971-6     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 33846414720 scopus 로고    scopus 로고
    • Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: Executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)
    • Ryden L, Standl E, Bartnik M et al (2007) Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: the Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD). Eur Heart J 28:88-136
    • (2007) Eur Heart J , vol.28 , pp. 88-136
    • Ryden, L.1    Standl, E.2    Bartnik, M.3
  • 2
    • 0034126089 scopus 로고    scopus 로고
    • Coronary atherosclerosis in Type II diabetes: Angiographic findings and clinical outcome
    • Natali A, Vichi S, Landi P, Severi S, L'Abbate A, Ferrannini E (2000) Coronary atherosclerosis in Type II diabetes: angiographic findings and clinical outcome. Diabetologia 43:632-641
    • (2000) Diabetologia , vol.43 , pp. 632-641
    • Natali, A.1    Vichi, S.2    Landi, P.3    Severi, S.4    L'Abbate, A.5    Ferrannini, E.6
  • 3
    • 33745661675 scopus 로고    scopus 로고
    • Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: Meta-analysis of randomized trials
    • Stettler C, Allemann S, Juni P et al (2006) Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: meta-analysis of randomized trials. Am Heart J 152:27-38
    • (2006) Am Heart J , vol.152 , pp. 27-38
    • Stettler, C.1    Allemann, S.2    Juni, P.3
  • 4
    • 0030034465 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilatation in patients with non-insulin-dependent diabetes mellitus
    • Ting H, Timimi F, Boles K, Creager S, Ganz P, Creager M (1996) Vitamin C improves endothelium-dependent vasodilatation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 97:22-28
    • (1996) J Clin Invest , vol.97 , pp. 22-28
    • Ting, H.1    Timimi, F.2    Boles, K.3    Creager, S.4    Ganz, P.5    Creager, M.6
  • 5
    • 0030007350 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus
    • Williams S (1996) Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 27:567-574
    • (1996) J Am Coll Cardiol , vol.27 , pp. 567-574
    • Williams, S.1
  • 6
    • 0032897441 scopus 로고    scopus 로고
    • Age-independent oxidative stress in elderly patients with non-insulin-dependent diabetes mellitus
    • Nuttal S, Dunne F, Kendal M, Martin U (1999) Age-independent oxidative stress in elderly patients with non-insulin-dependent diabetes mellitus. Q J Med 92:33-38
    • (1999) Q J Med , vol.92 , pp. 33-38
    • Nuttal, S.1    Dunne, F.2    Kendal, M.3    Martin, U.4
  • 7
    • 0344196080 scopus 로고    scopus 로고
    • NIDDM as a disease of the innate immune system: Association of acute-phase reactants and interleukin-6 with metabolic syndrome X
    • Pickup J, Mattock M, Chusney G, Burt D (1997) NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia 41:1241-1248
    • (1997) Diabetologia , vol.41 , pp. 1241-1248
    • Pickup, J.1    Mattock, M.2    Chusney, G.3    Burt, D.4
  • 8
    • 0031929810 scopus 로고    scopus 로고
    • The emerging role of post-prandial hyperglycaemic spikes in the pathogenesis of diabetic complication
    • Ceriello A (1998) The emerging role of post-prandial hyperglycaemic spikes in the pathogenesis of diabetic complication. Diab Med 15:188-193
    • (1998) Diab Med , vol.15 , pp. 188-193
    • Ceriello, A.1
  • 9
    • 0033972365 scopus 로고    scopus 로고
    • Resistance vessel endothelial function in healthy humans during transient post prandial hypertryglyceridemia
    • Gudmundsson G, Sinkey C, Chenard C, Stumbo P, Haynes W (2000) Resistance vessel endothelial function in healthy humans during transient post prandial hypertryglyceridemia. Am J Cardiol 85:381-385
    • (2000) Am J Cardiol , vol.85 , pp. 381-385
    • Gudmundsson, G.1    Sinkey, C.2    Chenard, C.3    Stumbo, P.4    Haynes, W.5
  • 10
    • 0029131083 scopus 로고
    • Hyperglycemia-induced thrombin formation in diabetes. the possible role of oxidative stress
    • Ceriello A, Giacomello R, Stel G et al (1995) Hyperglycemia-induced thrombin formation in diabetes. The possible role of oxidative stress. Diabetes 44:924-931
    • (1995) Diabetes , vol.44 , pp. 924-931
    • Ceriello, A.1    Giacomello, R.2    Stel, G.3
  • 11
    • 0038632123 scopus 로고    scopus 로고
    • Early and intermediate Amadori glycosylation adducts, oxidative stress, and endothelial dysfunction in the streptozotocin-induced diabetic rats vasculature
    • Rodriguez-Manas L, Angulo J, Vallejo S et al (2003) Early and intermediate Amadori glycosylation adducts, oxidative stress, and endothelial dysfunction in the streptozotocin-induced diabetic rats vasculature. Diabetologia 46:556-566
    • (2003) Diabetologia , vol.46 , pp. 556-566
    • Rodriguez-Manas, L.1    Angulo, J.2    Vallejo, S.3
  • 12
    • 0025832494 scopus 로고
    • Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C
    • Tesfamariam B, Brown L, Cohen R (1991) Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C. J Clin Invest 87:1643-1648
    • (1991) J Clin Invest , vol.87 , pp. 1643-1648
    • Tesfamariam, B.1    Brown, L.2    Cohen, R.3
  • 13
    • 0035180299 scopus 로고    scopus 로고
    • Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
    • Du XL, Edelstein D, Dimmeler S, Ju Q, Sui C, Brownlee M (2001) Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 108:1341-1348
    • (2001) J Clin Invest , vol.108 , pp. 1341-1348
    • Du, X.L.1    Edelstein, D.2    Dimmeler, S.3    Ju, Q.4    Sui, C.5    Brownlee, M.6
  • 14
    • 0024596673 scopus 로고
    • Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus
    • Mayhan WG (1989) Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus. Am J Physiol 256:H621-H625
    • (1989) Am J Physiol , vol.256
    • Mayhan, W.G.1
  • 15
    • 0028790808 scopus 로고
    • Chronic vitamin e treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta
    • Keegan A, Walbank H, Cotter MA, Cameron NE (1995) Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta. Diabetologia 38:1475-1478
    • (1995) Diabetologia , vol.38 , pp. 1475-1478
    • Keegan, A.1    Walbank, H.2    Cotter, M.A.3    Cameron, N.E.4
  • 16
    • 0029782820 scopus 로고    scopus 로고
    • Local 24-h hyperglycemia does not affect endothelium-dependent or -independent vasoreactivity in humans
    • Houben AJ, Schaper NC, De Haan CHA et al (1996) Local 24-h hyperglycemia does not affect endothelium-dependent or -independent vasoreactivity in humans. Am J Physiol 270:H2014-H2019
    • (1996) Am J Physiol , vol.270
    • Houben, A.J.1    Schaper, N.C.2    De Haan, C.H.A.3
  • 17
    • 0033935578 scopus 로고    scopus 로고
    • The effect of acute hyperglycaemia on brachial artery flow mediated dilatation in normal volunteers
    • Bagg W, Whalley GA, Sathu A, Gamble G, Sharpe N, Braatvedt GD (2000) The effect of acute hyperglycaemia on brachial artery flow mediated dilatation in normal volunteers. Aust NZ J Med 30:344-350
    • (2000) Aust NZ J Med , vol.30 , pp. 344-350
    • Bagg, W.1    Whalley, G.A.2    Sathu, A.3    Gamble, G.4    Sharpe, N.5    Braatvedt, G.D.6
  • 18
    • 0034849159 scopus 로고    scopus 로고
    • An ordinary mixed meal transiently impairs endothelium-dependent vasodilation in healthy subjects
    • Sarabi M, Fugmann A, Karlstrom B, Berne C, Lithell H, Lind L (2001) An ordinary mixed meal transiently impairs endothelium-dependent vasodilation in healthy subjects. Acta Physiol Scand 172:107-113
    • (2001) Acta Physiol Scand , vol.172 , pp. 107-113
    • Sarabi, M.1    Fugmann, A.2    Karlstrom, B.3    Berne, C.4    Lithell, H.5    Lind, L.6
  • 19
    • 4043069199 scopus 로고    scopus 로고
    • Lack of effect of oral glucose loading on conduit vessel endothelial function in healthy subjects
    • Siafarikas A, Watts K, Beye P, Jones TW, Davis EA, Green DJ (2004) Lack of effect of oral glucose loading on conduit vessel endothelial function in healthy subjects. Clin Sci (Lond) 107:191-196
    • (2004) Clin Sci (Lond) , vol.107 , pp. 191-196
    • Siafarikas, A.1    Watts, K.2    Beye, P.3    Jones, T.W.4    Davis, E.A.5    Green, D.J.6
  • 20
    • 11144328926 scopus 로고    scopus 로고
    • The postprandial state does not impair endothelial function in women with type 2 diabetes irrespective of glycaemic control
    • Strey CH, Young J, Collier M, Florkowski CM, Shand BI, Scott RS (2004) The postprandial state does not impair endothelial function in women with type 2 diabetes irrespective of glycaemic control. Diabetologia 47:1838-1846
    • (2004) Diabetologia , vol.47 , pp. 1838-1846
    • Strey, C.H.1    Young, J.2    Collier, M.3    Florkowski, C.M.4    Shand, B.I.5    Scott, R.S.6
  • 22
    • 0032485927 scopus 로고    scopus 로고
    • Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
    • Williams S, Goldfine A, Timimi F et al (1998) Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation 97:1695-1701
    • (1998) Circulation , vol.97 , pp. 1695-1701
    • Williams, S.1    Goldfine, A.2    Timimi, F.3
  • 23
    • 0033165758 scopus 로고    scopus 로고
    • Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery
    • Kawano H, Motoyama T, Hirashima O et al (1999) Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery. Am J Coll Cardiol 34:146-153
    • (1999) Am J Coll Cardiol , vol.34 , pp. 146-153
    • Kawano, H.1    Motoyama, T.2    Hirashima, O.3
  • 24
    • 0033673223 scopus 로고    scopus 로고
    • Oral glucose loading acutely attenuates endothelium-dependent vasodilation in healthy adults without diabetes: An effect prevented by vitamins C and e
    • Title LM, Cummings PM, Giddens K, Nassar BA (2000) Oral glucose loading acutely attenuates endothelium-dependent vasodilation in healthy adults without diabetes: an effect prevented by vitamins C and E. J Am Coll Cardiol 36:2185-2191
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2185-2191
    • Title, L.M.1    Cummings, P.M.2    Giddens, K.3    Nassar, B.A.4
  • 25
    • 0037015288 scopus 로고    scopus 로고
    • Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: Effects of short- and long-term simvastatin treatment
    • Ceriello A, Taboga C, Tonutti L et al (2002) Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment. Circulation 106:1211-1218
    • (2002) Circulation , vol.106 , pp. 1211-1218
    • Ceriello, A.1    Taboga, C.2    Tonutti, L.3
  • 26
    • 0034496602 scopus 로고    scopus 로고
    • Impaired flow-mediated vasoactivity during post-prandial phase in young healthy men
    • Marchesi S, Lupattelli G, Schillaci G et al (2000) Impaired flow-mediated vasoactivity during post-prandial phase in young healthy men. Atherosclerosis 153:397-402
    • (2000) Atherosclerosis , vol.153 , pp. 397-402
    • Marchesi, S.1    Lupattelli, G.2    Schillaci, G.3
  • 27
    • 0028800873 scopus 로고
    • Effect of insulin on acetylcholine-induced vasodilation in normal subjects and in patients with essential hypertension
    • Taddei S, Virdis A, Mattei P, Natali A, Ferrannini E, Salvetti A (1995) Effect of insulin on acetylcholine-induced vasodilation in normal subjects and in patients with essential hypertension. Circulation 92:2911-2918
    • (1995) Circulation , vol.92 , pp. 2911-2918
    • Taddei, S.1    Virdis, A.2    Mattei, P.3    Natali, A.4    Ferrannini, E.5    Salvetti, A.6
  • 28
    • 0036316948 scopus 로고    scopus 로고
    • Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia
    • Serne EH, IJzermam RG, Gans RO et al (2002) Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia. Diabetes 51:1515-1522
    • (2002) Diabetes , vol.51 , pp. 1515-1522
    • Serne, E.H.1    Ijzermam, R.G.2    Gans, R.O.3
  • 29
    • 3142677991 scopus 로고    scopus 로고
    • Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers
    • de Jongh RT, Clark AD, IJzermam RG, Serne EH, de Vries G, Stehouwer CD (2004) Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers. Diabetologia 47:978-986
    • (2004) Diabetologia , vol.47 , pp. 978-986
    • De Jongh, R.T.1    Clark, A.D.2    Ijzermam, R.G.3    Serne, E.H.4    De Vries, G.5    Stehouwer, C.D.6
  • 30
    • 0030586361 scopus 로고    scopus 로고
    • The ferric reducing ability of the plasma (FRAP) as a measure of "antioxidant power": The FRAP assay
    • Benzie I, Strain J (1996) The ferric reducing ability of the plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 15:70-76
    • (1996) Anal Biochem , vol.15 , pp. 70-76
    • Benzie, I.1    Strain, J.2
  • 31
    • 0028167732 scopus 로고
    • Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine
    • Nourooz-Zadeh J, Tajaddin-Sarmadi J, Wolff SP (1994) Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine. Anal Biochem 220:403-409
    • (1994) Anal Biochem , vol.220 , pp. 403-409
    • Nourooz-Zadeh, J.1    Tajaddin-Sarmadi, J.2    Wolff, S.P.3
  • 32
    • 33847615135 scopus 로고    scopus 로고
    • LDL resistance to oxidation: Effects of lipid phenotype, autologous HDL and alanine
    • Baldi S, Frascerra S, Ferrannini E, Natali A (2007) LDL resistance to oxidation: effects of lipid phenotype, autologous HDL and alanine. Clin Chim Acta 379:95-100
    • (2007) Clin Chim Acta , vol.379 , pp. 95-100
    • Baldi, S.1    Frascerra, S.2    Ferrannini, E.3    Natali, A.4
  • 33
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G, Nystrom FH, Ravichandran LV et al (2000) Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101:1539-1545
    • (2000) Circulation , vol.101 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3
  • 34
    • 2642572617 scopus 로고    scopus 로고
    • Impaired microvascular function in obesity: Implications for obesity-associated microangiopathy, hypertension, and insulin resistance
    • de Jongh RT, Serne EH, IJzermam RG, de Vries G, Stehouwer CD (2004) Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance. Circulation 109:2529-2535
    • (2004) Circulation , vol.109 , pp. 2529-2535
    • De Jongh, R.T.1    Serne, E.H.2    Ijzermam, R.G.3    De Vries, G.4    Stehouwer, C.D.5
  • 35
    • 0035516041 scopus 로고    scopus 로고
    • Insulin therapy improves insulin-stimulated endothelial function in patients with type 2 diabetes and ischemic heart disease
    • Rask-Madsen C, Ihlemann N, Krarup T et al (2001) Insulin therapy improves insulin-stimulated endothelial function in patients with type 2 diabetes and ischemic heart disease. Diabetes 50:2611-2618
    • (2001) Diabetes , vol.50 , pp. 2611-2618
    • Rask-Madsen, C.1    Ihlemann, N.2    Krarup, T.3
  • 36
    • 0030921893 scopus 로고    scopus 로고
    • Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation
    • Steinberg H, Tarshoby M, Monestel R et al (1997) Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation. J Clin Invest 100:1230-1239
    • (1997) J Clin Invest , vol.100 , pp. 1230-1239
    • Steinberg, H.1    Tarshoby, M.2    Monestel, R.3
  • 37
    • 0030801087 scopus 로고    scopus 로고
    • Reversal by l-arginine of a dysfunctional arginine-nitric oxide pathway in endothelium of the genetic diabetic BB rat
    • Pieper G, Siebeneich W, Moore-Hilton G, Roza A (1997) Reversal by l-arginine of a dysfunctional arginine-nitric oxide pathway in endothelium of the genetic diabetic BB rat. Diabetologia 40:910-915
    • (1997) Diabetologia , vol.40 , pp. 910-915
    • Pieper, G.1    Siebeneich, W.2    Moore-Hilton, G.3    Roza, A.4
  • 38
    • 0034235409 scopus 로고    scopus 로고
    • Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency
    • Meininger CJ, Marinos RS, Hatakeyama K et al (2000) Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency. Biochem J 349:353-356
    • (2000) Biochem J , vol.349 , pp. 353-356
    • Meininger, C.J.1    Marinos, R.S.2    Hatakeyama, K.3
  • 39
    • 0037022206 scopus 로고    scopus 로고
    • Insulin causes endothelial dysfunction in humans: Sites and mechanisms
    • Arcaro G, Cretti A, Balzano S et al (2002) Insulin causes endothelial dysfunction in humans: sites and mechanisms. Circulation 105:576-582
    • (2002) Circulation , vol.105 , pp. 576-582
    • Arcaro, G.1    Cretti, A.2    Balzano, S.3
  • 40
    • 0347628963 scopus 로고    scopus 로고
    • Insulin impairs endothelium-dependent vasodilation independent of insulin sensitivity or lipid profile
    • Campia U, Sullivan G, Bryant MB, Waclawiw MA, Quon MJ, Panza JA (2004) Insulin impairs endothelium-dependent vasodilation independent of insulin sensitivity or lipid profile. Am J Physiol 286:H76-H82
    • (2004) Am J Physiol , vol.286
    • Campia, U.1    Sullivan, G.2    Bryant, M.B.3    Waclawiw, M.A.4    Quon, M.J.5    Panza, J.A.6
  • 41
    • 0035957267 scopus 로고    scopus 로고
    • Ascorbate restores endothelium-dependent vasodilatation impaired by acute hyperglycemia in humans
    • Beckman J, Goldfine A, Gordon M, Creager M (2001) Ascorbate restores endothelium-dependent vasodilatation impaired by acute hyperglycemia in humans. Circulation 103:1618-1623
    • (2001) Circulation , vol.103 , pp. 1618-1623
    • Beckman, J.1    Goldfine, A.2    Gordon, M.3    Creager, M.4
  • 42
    • 0028274304 scopus 로고
    • Free radicals in diabetic endothelial cell dysfunction
    • Tesfamariam B (1994) Free radicals in diabetic endothelial cell dysfunction. Free Radic Biol Med 16:383-391
    • (1994) Free Radic Biol Med , vol.16 , pp. 383-391
    • Tesfamariam, B.1
  • 43
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino F, Hishikawa K, Katusic ZS, Luscher TF (1997) High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96:25-28
    • (1997) Circulation , vol.96 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Luscher, T.F.4
  • 44
    • 0031977246 scopus 로고    scopus 로고
    • Antioxidant defenses are reduced during oral glucose tolerance test in normal and non-insulin dependent diabetic subjects
    • Ceriello A, Bortolotti N, Crescentini A et al (1998) Antioxidant defenses are reduced during oral glucose tolerance test in normal and non-insulin dependent diabetic subjects. Eur J Clin Invest 28:329-334
    • (1998) Eur J Clin Invest , vol.28 , pp. 329-334
    • Ceriello, A.1    Bortolotti, N.2    Crescentini, A.3
  • 45
    • 20944448256 scopus 로고    scopus 로고
    • A study of the effect of oral glucose loading on plasma oxidant:antioxidant balance in normal subjects
    • Ma SW, Tomlinson B, Benzie IF (2005) A study of the effect of oral glucose loading on plasma oxidant:antioxidant balance in normal subjects. Eur J Nutr 44:250-254
    • (2005) Eur J Nutr , vol.44 , pp. 250-254
    • Ma, S.W.1    Tomlinson, B.2    Benzie, I.F.3
  • 46
    • 33745324596 scopus 로고    scopus 로고
    • Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes
    • Natali A, Toschi E, Baldeweg S et al (2006) Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes. Diabetes 55:1133-1140
    • (2006) Diabetes , vol.55 , pp. 1133-1140
    • Natali, A.1    Toschi, E.2    Baldeweg, S.3
  • 47
    • 0029857841 scopus 로고    scopus 로고
    • Dissociation between insulin sensitivity of glucose uptake and endothelial function in normal subjects
    • Utriainen T, Mäkimattila S, Virkamäki A, Bergholm R, Yki-Järvinen H (1996) Dissociation between insulin sensitivity of glucose uptake and endothelial function in normal subjects. Diabetologia 39:1477-1482
    • (1996) Diabetologia , vol.39 , pp. 1477-1482
    • Utriainen, T.1    Mäkimattila, S.2    Virkamäki, A.3    Bergholm, R.4    Yki-Järvinen, H.5
  • 48
    • 0030792915 scopus 로고    scopus 로고
    • Insulin sensitivity, vascular reactivity, and clamp-induced vasodilatation in essential hypertension
    • Natali A, Taddei S, Quinones-Galvan A et al (1997) Insulin sensitivity, vascular reactivity, and clamp-induced vasodilatation in essential hypertension. Circulation 96:849-855
    • (1997) Circulation , vol.96 , pp. 849-855
    • Natali, A.1    Taddei, S.2    Quinones-Galvan, A.3


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