Local 24-h hyperglycemia does not affect endothelium-dependent or - independent vasoreactivity in humans

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 270, Issue 6 39-6, 1996, Pages

  Houben, A J H M ^a   Schaper, N C ^b   De Haan, C H A ^b   Huvers, F C ^b   Slaaf, D W ^b   De Leeuw, P W ^b   Nieuwenhuijzen Kruseman, A C ^b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

diabetes mellitus; forearm blood flow; intra arterial infusion; N(G) monomethyl L arginine; nitric oxide; vascular reactivity

Indexed keywords

ACETYLCHOLINE; NITROPRUSSIDE SODIUM; NORADRENALIN;

ADULT; ARTICLE; BLOOD VESSEL REACTIVITY; BRACHIAL ARTERY; COLOR ULTRASOUND FLOWMETRY; DIABETIC MICROANGIOPATHY; FOREARM BLOOD FLOW; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIA; MALE; PRIORITY JOURNAL; SKIN BLOOD FLOW;

EID: 0029782820     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.6.h2014     Document Type: Article

References (31)

1. Anderson, E. A., and A. L. Mark. The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension. Hypertension Dallas 21: 136-141, 1993.
2. Benjamin, N., A. Calver, J. Collier, B. Robinson, P. Vallance, and D. Webb. Measuring forearm blood flow and interpreting the responses to drugs and mediators. Hypertension Dallas 25: 918-923, 1995.
3. 3 receptor antagonist ICS 205-930 Life Sci. 43: 1441-1449, 1983.
4. Bodmer, C. W., A. W. Patrick, and G. Williams. Exaggerated sensitivity to NE-induced vasoconstriction in IDDM patients with microalbuminuria. Possible etiology and diagnostic implications. Diabetes 41: 209-214, 1992.
5. 2-adrenoceptor-mediated vasoconstriction in insulin-dependent diabetic patients with microalbuminuria. Clin. Sci. Lond. 88: 421-426, 1995.
6. 3-receptor. J. Cardiovasc. Pharmacol. 22: 44-51, 1993.
7. Bucala, R., K. J. Tracey, and A. Cerami. Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. J. Clin. Invest. 87: 432-438, 1991.
8. Calver, A., J. Collier, and P. Vallance. Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J. Clin. Invest. 90: 2548-2554, 1992.
9. Cameron, N. E., and M. A. Cotter. Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: role of polyol pathway. Diabetologia 35: 1011-1019, 1992.
10. Christiansen, J. S., J. Gammelgaard, B. Tronier, P. A. Svendsen, and H. H. Parving. Kidney function and size in diabetics before and during initial insulin treatment. Kidney Int. 21: 683-688, 1982.
11. Christlieb, A. R., H. U. Janka, B. Kraus, R. E. Gleason, E. A. Icasas-Cabral, L. M. Aiello, B. V. Cabral, and A. Solano. Vascular reactivity to angiotensin II and to norepinephrine in diabetic subjects. Diabetes 25: 268-274, 1976.
12. Cooper, K. E., O. G. Edholm, and R. F. Mottram. The blood flow in skin and muscle of the human forearm. J. Physiol. Lond. 128: 208-267, 1955.
13. Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329: 977-986, 1993.
14. Elliott, T. G., J. R. Cockcroft, P. H. Groop, G. C. Viberti, and J. M. Ritter. Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependnent diabetic patients: blunted vasoconstriction in patients with microalbuminuria. Clin. Sci. Lond. 85: 687-693, 1993.
15. Greenfield, A. D. M., and G. C. Patterson. Reactions of the blood vessels of the human forearm to increase in transmural pressure. J. Physiol. Lond. 125: 508-524, 1954.
16. Grunwald, J. E., A. J. Brucker, S. S. Schwartz, S. N. Braunstein, L. Baker, B. L. Petrig, and C. E. Riva. Diabetic glycemic control and retinal blood flow. Diabetes 39: 602-607, 1990.
17. Halkin, A., N. Benjamin, H. S. Doktor, S. D. Todd, G. Viberti, and J. M. Ritter. Vascular responsiveness and cation exchange in insulin-dependent diabetes. Clin. Sci. Lond. 81: 223-232, 1991.
18. Houben, A. J. H. M., A. C. Nieuwenhuijzen Kruseman, E. Bouhouch, D. W. Slaaf, and N. C. Schaper. Peripheral macroand microcirculation in short-term insulin-dependent diabetes mellitus: the role of prostaglandins in early haemodynamic changes. Eur. J. Clin. Invest. 23: 662-667, 1993.
19. Houben, A. J. H. M., D. W. Slaaf, F. C. Huvers, P. W. de Leeuw, A. C. Nieuwenhuijzen Kruseman, and N. C. Schaper. Diurnal variations in total forearm and skin microcirculatory blood flow in man. Scand. J. Clin. Lab. Invest. 54: 161-169, 1994.
20. Huvers, F. C., A. J. H. M. Houben, C. H. A. de Haan, P. W. de Leeuw, A. C. Nieuwenhuijzen Kruseman, and N. C. Schaper. Local hyperinsulinaemia increases forearm blood flow, but does not affect the aoradrenaline sensitivity (Abstract). Diabetologia 37, Suppl. 1:A142, 1994.
21. Langenstroer, P., and G. M. Pieper. Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H257-H263, 1992.
22. Mayhan, W. G. Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus. Am. J. Physiol 256 (Heart Circ. Physiol 25): H621-H625, 1989.
23. Sandeman, D. D., A. C. Shore, and J. E. Tooke. Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control. N. Engl. J. Med. 327: 760-764, 1992.
24. Smits, P., J. A. Kapma, M. C. Jacobs, J. Lutterman, and T. Thien. Endothelium-dependent vascular relaxation in patients with type I diabetes. Diabetes 42: 148-153, 1993.
25. Stephenson, L. A., and M. A. Kolka. Acetylcholinesterase inhibitor, pyridostigmine bromide, reduces skin blood flow in humans. Am. J. Physiol. 258 (Regulatory Integrative Comp. Physiol. 27): R951-R957, 1990.
26. Thuesen, L., J. Sandahl-Christiansen, O. Schmitz, N. J. Christensen, H. Orskov, and P. Henningsen. Increased myocardial performance following acute hyperglycaemia in insulin-dependent diabetic patients. A consequence of increased peripheral blood flow? Scand. J. Clin. Lab. Invest. 47: 571-579, 1987.
27. Tilton, R. G., K. Chang, K. S. Hasan, S. R. Smith, M. Petrash, T. P. Misko, T. M. Moore, M. G. Currie, J. A. Corbett, M. L. McDaniel, and J. R. Williamson. Prevention of diabetic vascular dysfunction by guanidines. Diabetes 42: 221-232, 1993.
28. Tooke, J. E. Microvascular haemodynamics in diabetes mellitus. Clin. Sci. Lond. 70: 119-125, 1986.
29. Williamson, J. R., C. Kilo, and R. G. Tilton. Mechanisms of glucose- and diabetes-induced vascular dysfunction. In: Hyperglycemia, Diabetes, and Vascular Disease, edited by N. Ruderman, J. R. Williamson, and M. Brownlee. New York: Oxford Univ. Press, 1992, p. 107-132.
30. Williamson, J. R., E. Ostrow, D. Eades, K. Chang, W. Allison, C. Kilo, and W. R. Sherman. Glucose-induced microvascular functional changes in nondiabetic rats are stereospecific and are prevented by an aldose reductase inhibitor. J. Clin. Invest. 85: 1167-1172, 1990.
31. Woods, L. L., H. L. Mizelle, and J. E. Hall. Control of renal hemodynamics in hyperglycemia: possible role of tubuloglomerular feedback. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21):F65-F73, 1987.