Controlled protein release from electrospun biodegradable fiber mesh composed of poly(ε-caprolactone) and poly(ethylene oxide)

International Journal of Pharmaceutics

Volumn 338, Issue 1-2, 2007, Pages 276-283

  Kim, Taek Gyoung ^a   Lee, Doo Sung ^b   Park, Tae Gwan ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Biodegradable; Electro spinning; Lysozyme; Nanofibers; Protein release

Indexed keywords

BUFFER; CHLOROFORM; DIMETHYL SULFOXIDE; LYSOZYME; MACROGOL; POLYCAPROLACTONE; POLYGLACTIN; POLYLACTIC ACID; POLYMER;

ARTICLE; BIODEGRADABILITY; CONTROLLED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENZYME ACTIVITY; HYDROPHILICITY; HYDROPHOBICITY; INCUBATION TIME; PRIORITY JOURNAL;

DELAYED-ACTION PREPARATIONS; MURAMIDASE; POLYESTERS; POLYETHYLENE GLYCOLS; PROTEINS; SOLUBILITY;

EID: 34248639861     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.01.040     Document Type: Article

References (28)

1. Breitbart A.S., Grande D.A., Laser J., Barcia M., Porti D., Malhotra S., Kogon A., Grant R.T., and Mason J.M. Treatment of ischemic wounds using cultured dermal fibroblasts transduced retrovirally with PDGF-B and VEGF121 genes. Ann. Plast. Surg. 46 (2001) 555-561
2. Casper C.L., Yamaguchi N., Kiick K.L., and Rabolt J.F. Functionalizing electrospun fibers with biologically relevant macromolecules. Biomacromolecules 6 (2005) 1998-2007
3. Chew S.Y., Wen J., Yim E.K., and Leong K.W. Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules 6 (2005) 2017-2024
4. Dai C., Wang B., and Zhao H. Microencapsulation peptide and protein drugs delivery system. Colloid Surf. B Biointerfaces 41 (2005) 117-120
5. Doshi J., and Reneker D.H. Electrospinning process and applications of electrospun fibers. J. Electrost. 35 (1995) 151-160
6. Fridrikh S.V., Yu J.H., Brenner M.P., and Rutledge G.C. Controlling the fiber diameter during electrospinning. Phys. Rev. Lett. 90 (2003) 144502
7. Jiang H., Hu Y., Li Y., Zhao P., Zhu K., and Chen W. A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents. J. Control. Release 108 (2005) 237-243
8. Jiang H., Hu Y., Zhao P., Li Y., and Zhu K. Modulation of protein release from biodegradable core-shell structured fibers prepared by coaxial electrospinning. J. Biomed. Mater. Res. Part B 79 (2006) 50-57
9. Khil M.S., Bhattarai S.R., Kim H.Y., Kim S.Z., and Lee K.H. Novel fabricated matrix via electrospinning for tissue engineering. J. Biomed. Mater. Res. Part B 72 (2005) 117-124
10. Kim H.K., and Park T.G. Comparative study on sustained release of human growth hormone from semi-crystalline poly(l-lactic acid) and amorphous poly(d,l-lactic-co-glycolic acid) microspheres: morphological effect on protein release. J. Control. Release 98 (2004) 115-125
11. Kim K., Luu Y.K., Chang C., Fang D., Hsiao B.S., Chu B., and Hadjiargyrou M. Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds. J. Control. Release 98 (2004) 47-56
12. Kim T.G., and Park T.G. Biomimicking extracellular matrix: Cell adhesive RGD peptide modified electrospun poly(d,l-lactic-co-glycolic acid) nanofiber mesh. Tissue Eng. 12 (2006) 221-233
13. Luu Y.K., Kim K., Hsiao B.S., Chu B., and Hadjiargyrou M. Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA-PEG block copolymers. J. Control. Release 89 (2003) 341-353
14. Miller-Chou B.A., and Koenig J.L. A review of polymer dissolution. Prog. Polym. Sci. 28 (2003) 1223-1270
15. Mo X.M., Xu C.Y., Kotaki M., and Ramakrishna S. Electrospun P(LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation. Biomaterials 25 (2004) 1883-1890
16. Na Y.H., He Y., Shuai X., Kikkawa Y., Doi Y., and Inoue Y. Compatibilization effect of poly(epsilon-caprolactone)-b-poly(ethylene glycol) block copolymers and phase morphology analysis in immiscible poly(lactide)/poly(epsilon-caprolactone) blends. Biomacromolecules 3 (2002) 1179-1186
17. Nijenhuis A.J., Colstee E., Grijpma D.W., and Pennings A.J. High molecular weight poly(l-lactide) and poly(ethylene oxide) blends: Thermal characterization and physical properties. Polymer 37 (1996) 5849-5857
18. Pandit A.S., Wilson D.J., and Feldman D.S. Fibrin scaffold as an effective vehicle for the delivery of acidic fibroblast growth factor (FGF-1). J. Biomater. Appl. 14 (2000) 229-242
19. Park T.G., Cohen S., and Langer R. Poly(l-lactic acid) pluronic blends-characterization of phase-separation behavior, degradation, and morphology and use as protein-releasing matrices. Macromolecules 25 (1992) 116-122
20. Park T.G., Lee H.Y., and Nam Y.S. A new preparation method for protein loaded poly(d,l-lactic-co-glycolic acid) microspheres and protein release mechanism study. J. Control. Release 55 (1998) 181-191
21. Perez C., De Jesus P., and Griebenow K. Preservation of lysozyme structure and function upon encapsulation and release from poly(lactic-co-glycolic) acid microspheres prepared by the water-in-oil-in-water method. Int. J. Pharm. 248 (2002) 193-206
22. Theron S.A., Zussman E., and Yarin A.L. Experimental investigation of the governing parameters in the electrospinning of polymer solutions. Polymer 45 (2004) 2017-2030
23. Xu X., Yang L., Xu X., Wang X., Chen X., Liang Q., Zeng J., and Jing X. Ultrafine medicated fibers electrospun from W/O emulsions. J. Control. Release 108 (2005) 33-42
24. Zeng J., Aigner A., Czubayko F., Kissel T., Wendorff J.H., and Greiner A. Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. Biomacromolecules 6 (2005) 1484-1488
25. Zeng J., Xu X., Chen X., Liang Q., Bian X., Yang L., and Jing X. Biodegradable electrospun fibers for drug delivery. J. Control. Release 92 (2003) 227-231
26. Zeng J., Yang L., Liang Q., Zhang X., Guan H., Xu X., Chen X., and Jing X. Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation. J. Control. Release 105 (2005) 43-51
27. Zong X., Kim K., Fang D., Ran S., Hsiao B.S., and Chu B. Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer 43 (2002) 4403-4412
28. Zong X., Ran S., Kim K.S., Fang D., Hsiao B.S., and Chu B. Structure and morphology changes during in vitro degradation of electrospun poly(glycolide-co-lactide) nanofiber membrane. Biomacromolecules 4 (2003) 416-423