Encapsulation of drug reservoirs in fibers by emulsion electrospinning: Morphology characterization and preliminary release assessment

Biomacromolecules

Volumn 7, Issue 8, 2006, Pages 2327-2330

  Qi, Hongxu ^a   Hu, Ping ^a   Xu, Jun ^a   Wang, Aijun ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; ELECTROSPINNING; SPRAY-DRYING TECHNIQUES;

DRUG PRODUCTS; ENCAPSULATION; HYDROPHILICITY; MICROEMULSIONS; MORPHOLOGY; SCANNING ELECTRON MICROSCOPY; SPINNING (FIBERS);

FIBER REINFORCED MATERIALS;

BOVINE SERUM ALBUMIN; CALCIUM ALGINATE; DRUG CARRIER; MICROSPHERE; POLYLACTIC ACID;

ARTICLE; CHEMICAL STRUCTURE; DRUG DELIVERY SYSTEM; DRUG RELEASE; EMULSION; ENCAPSULATION; HYDROPHOBICITY; IN VITRO STUDY; INTERMETHOD COMPARISON; MICROCAPSULE; MICROENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; SPRAY DRYING;

ALGINATES; ANIMALS; CATTLE; DELAYED-ACTION PREPARATIONS; DESICCATION; EMULSIONS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; HYDROPHOBICITY; LACTATES; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; NANOSTRUCTURES; SERUM ALBUMIN, BOVINE;

BOS TAURUS;

EID: 33748340268     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm060264z     Document Type: Article

References (29)

1. Langer, R. Biomaterials in drug delivery and tissue engineering: One laboratory's experience. Acc. Chem. Res. 2003, 3, 94-101.
2. Baldwin, S. P.; Saltzman, W. M. Materials for protein delivery in tissue engineering. Adv. Drug Deliv. Rev. 1998, 33, 71-86.
3. Babensee, J. E.; Mcintire, L. V.; Mikos, A. G. Growth Factor Delivery for Tissue Engineering. Pharm. Res. 2000, 17, 497-504.
4. Anderson, J. M.; Shive, M. S. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev. 1997, 28, 5-24.
5. O'Donnell, P. B.; McGinity, J. W. Preparation of microspheres by the solvent evaporation technique. Adv. Drug Deliv. Rev. 1997, 28, 25-42.
6. Richardson, T. P.; Peters, M. C.; Ennett, A. B.; Mooney, D. J. Polymeric system for dual growth factor delivery. Nat. Biotechnol. 2001, 19, 1029-1034.
7. Lee, D. W.; Hwang, S. J.; Park, J. B.; Park, H. J. Preparation and release characteristics of polymer-coated and blended alginate microspheres. J. Microencapsul. 2003, 20, 179-192.
8. Park, T. G.; Alonso, M. J.; Langer, R. Controlled-Release of Proteins from Poly(L-Lactic Acid) Coated Polyisobutylcyanoacrylate Micro-capsules. J. Appl. Polym. Sci. 1994, 52, 1797-1807.
9. Freitas, S.; Merkle H. P.; Gander, B. Microencapsulation by solvent extraction/evaporation: reviewing the state of the art of microsphere preparation process technology. J. Controlled Release 2005, 102, 313-332.
10. Hu, Y.; Hollinger, J. O.; Marra, K. G. Incorporation of polymer microspheres within fibrin scaffolds. J. Drug Targeting 2001, 9, 431-438.
11. Borden, M.; Attawia, M.; Laurencin, C. T. The sintered microsphere matrix for bone tissue engineering: In vitro osteoconductivity studies. J. Biomed. Mater. Res. 2002, 61, 421-429.
12. Venugopal, J.; Ramakrishna, S. Applications of polymer nanofibers in biomedicine and biotechnology. Appl. Biochem. Biotechnol. 2005, 125, 147-157.
13. Kenawy, E. R.; Bowlin, G. L.; Mansfield, K.; Layman J.; Simpson, D. G.; Sanders, E. H.; Wnek, G. E. Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinyl acetate), poly-(lactic acid), and a blend. J. Controlled Release 2002, 81, 57-64.
14. Li, W. J.; Laurencin, C. T.; Caterson, E. J.; Tuan, R. S.; Ko, F. K. Electrospun nanofibrous structure: A novel scaffold for tissue engineering. J. Biomed. Mater. Res. 2002, 60, 613-621.
15. Chew, S. Y.; Wen, J.; Yim, E. K. F.; Leong, K. W. Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules 2005, 6, 2017-2024.
16. Li, M. Y.; Mondrinos, M. J.; Gandhi, M. R.; Ko, F. K.; Weiss, A. S.; Lelkes, P. Electrospun protein fibers as matrices for tissue engineering. Biomaterials 2005, 6, 5999-6008.
17. Loscertales, I. G.; Barrero, A.; Guerrero, I.; Cortijo R.; Marquez, M.; Ganan-Calvo, A. M. Micro/nano encapsulation via electrified coaxial liquid jets. Science 2002, 295, 1695-1698.
18. Larsen, G.; Spretz R.; Velarde-Ortiz, R. Use of coaxial gas jackets to stabilize Taylor cones of volatile solutions and to induce particle-to-fiber transitions. Adv. Mater. 2004, 16, 166-169.
19. Sun, Z. C.; Zussman, E.; Yarin, A. L.; Wendorff, J. H.; Greiner, A. Compound core-shell polymer nanofibers by co-electrospinning. Adv. Mater. 2003, 15, 1929-1932.
20. Li, D.; Xia, Y. N. Direct fabrication of composite and ceramic hollow nanofibers by electrospinning. Nano Lett. 2004, 4, 933-938.
21. Sanders, E. H.; Kloefkorn, R.; Bowlin, G. L.; Simpson, D. G.; Wnek, G. E. Two-phase electrospinning from a single electrified jet: Microencapsulation of aqueous reservoirs in poly(ethylene-co-vinyl acetate) fibers. Macromolecules 2003, 36, 3803-3805.
22. Xu, X. L.; Yang, L. X.; Xu, X. Y., Wang, X.; Chen, X. S.; Liang, Q. Z.; Zeng, J.; Jing, X. B. Ultrafine medicated fibers electrospun from W/O emulsions. J. Controlled Release 2005, 108, 33-42.
23. Gombotz, W. R.; Wee, S. F. Protein release from alginate matrices. Adv. Drug Deliv. Rev. 1998, 31, 267-285.
24. Jin-Oh, Y.; Ching-An, P. Calcium-alginate Nanoparticles formed by reverse Microemulsion as Gene Carriers. Macromol. Symp. 2005, 219, 147-153.
25. Fong, H.; Chun, I.; Reneker, D. H. Beaded nanofibers formed during electrospinning. Polymer 1999, 40, 4585-4592.
26. Zuo, W. W.; Zhu, M. F.; Yang, W.; Yu, H.; Chen, Y. M.; Zhang, Y. Experimental study on relationship between jet instability and formation of beaded fibers during electrospining. Polym. Eng. Sci. 2005, 45, 704-709.
27. Zheng, C. H.; Gao, J. Q.; Zhang, Y. P.; Liang, W. Q. A protein delivery system: biodegradable Alginate-chitosan-poly (lactic-co-glycolic acid) composite microspheres. Biochem. Biophys. Res. Commun. 2004, 323, 1321-1327.
28. Lemoine, D.; Wauters, F.; Bouchend'homme, S.; Preat, V. Preparation and characterization of alginate microspheres containing a model antigen. Int. J. Pharm. 1998, 176, 9-19.
29. Yarin, A. L.; Koombhongse, S.; Reneker, D. H. Bending instability in electrospinning of nanofibers. J. Appl. Phys. 2001, 89, 3018-3026.