Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic

Tetrahedron

Volumn 64, Issue 19, 2008, Pages 4332-4346

  Narumi, Tetsuo ^a   Tomita, Kenji ^a   Inokuchi, Eriko ^a   Kobayashi, Kazuya ^a   Oishi, Shinya ^a   Ohno, Hiroaki ^a   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

CXCR4 antagonist; Fluoroalkene; Peptide isosteres; Transmetalation

Indexed keywords

9H FLUOREN 9 YLMETHOXY CARBONYL; ALKENE DERIVATIVE; CARBONYL DERIVATIVE; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; DIPEPTIDE DERIVATIVE; FLUOROALKENE; PENTAPEPTIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CYCLIZATION; DIASTEREOISOMER; DRUG SYNTHESIS; ISOMERIZATION; ONE POT SYNTHESIS; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS; STEREOCHEMISTRY; X RAY DIFFRACTION;

EID: 41549104832     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.02.076     Document Type: Article

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