-
1
-
-
33846008339
-
Cell cycle quiescence of early lymphoid progenitors in adult bone marrow
-
Pelayo R, Miyazaki K, Huang J, Garrett KP, Osmond DG, et al. (2006) Cell cycle quiescence of early lymphoid progenitors in adult bone marrow. Stem Cells 24: 2703-2713.
-
(2006)
Stem Cells
, vol.24
, pp. 2703-2713
-
-
Pelayo, R.1
Miyazaki, K.2
Huang, J.3
Garrett, K.P.4
Osmond, D.G.5
-
3
-
-
33645469482
-
Stem cells and their niches
-
Moore KA, Lemischka IR (2006) Stem cells and their niches. Science 311: 1880-1885.
-
(2006)
Science
, vol.311
, pp. 1880-1885
-
-
Moore, K.A.1
Lemischka, I.R.2
-
4
-
-
0032980506
-
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
-
Cheshier SH, Morrison SJ, Liao X, Weissman IL (1999) In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci U S A 96: 3120-3125.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3120-3125
-
-
Cheshier, S.H.1
Morrison, S.J.2
Liao, X.3
Weissman, I.L.4
-
5
-
-
1642603951
-
Socializing with the neighbors: Stem cells and their niche
-
Fuchs E, Tumbar T, Guasch G (2004) Socializing with the neighbors: stem cells and their niche. Cell 116: 769-778.
-
(2004)
Cell
, vol.116
, pp. 769-778
-
-
Fuchs, E.1
Tumbar, T.2
Guasch, G.3
-
6
-
-
0034614576
-
Stem cells: Units of development, units of regeneration, and units in evolution
-
Weissman IL (2000) Stem cells: units of development, units of regeneration, and units in evolution. Cell 100: 157-168.
-
(2000)
Cell
, vol.100
, pp. 157-168
-
-
Weissman, I.L.1
-
8
-
-
33745712791
-
Stem cells and cancer: An intimate relationship
-
Burkert J, Wright NA, Alison MR (2006) Stem cells and cancer: an intimate relationship. J Pathol 209: 287-297.
-
(2006)
J Pathol
, vol.209
, pp. 287-297
-
-
Burkert, J.1
Wright, N.A.2
Alison, M.R.3
-
10
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414: 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
12
-
-
0842281433
-
Therapeutic implications of cancer stem cells
-
Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF (2004) Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14: 43-47.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 43-47
-
-
Al-Hajj, M.1
Becker, M.W.2
Wicha, M.3
Weissman, I.4
Clarke, M.F.5
-
13
-
-
33845664398
-
Primitive, quiescent and difficult to kill: The role of non-proliferating stem cells in chronic mycloid leukemia
-
Barnes DJ, Melo JV (2006) Primitive, quiescent and difficult to kill: the role of non-proliferating stem cells in chronic mycloid leukemia. Cell Cycle 5: 2862-2866.
-
(2006)
Cell Cycle
, vol.5
, pp. 2862-2866
-
-
Barnes, D.J.1
Melo, J.V.2
-
14
-
-
0033568250
-
Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic mycloid leukemia
-
Holyoake T, Jiang X, Eaves C, Eaves A (1999) Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic mycloid leukemia. Blood 94: 2056-2064.
-
(1999)
Blood
, vol.94
, pp. 2056-2064
-
-
Holyoake, T.1
Jiang, X.2
Eaves, C.3
Eaves, A.4
-
15
-
-
0035254540
-
Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3
-
Holyoake TL, Jiang X, Jorgensen HG, Graham S, Alcorn MJ, et al. (2001) Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3. Blood 97: 720-728.
-
(2001)
Blood
, vol.97
, pp. 720-728
-
-
Holyoake, T.L.1
Jiang, X.2
Jorgensen, H.G.3
Graham, S.4
Alcorn, M.J.5
-
16
-
-
0036090222
-
Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to ST1571 in vitro
-
Graham SM, Jorgensen HG, Allan E, Pearson C, Alcorn MJ, et al. (2002) Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to ST1571 in vitro. Blood 99: 319-325.
-
(2002)
Blood
, vol.99
, pp. 319-325
-
-
Graham, S.M.1
Jorgensen, H.G.2
Allan, E.3
Pearson, C.4
Alcorn, M.J.5
-
17
-
-
4344564827
-
Chronic myeloid leukemia
-
Am See Hematol Educ Program, pp
-
Melo JV, Hughes TP, Apperley JF (2003) Chronic myeloid leukemia. Hematology (Am See Hematol Educ Program). pp 132-152.
-
(2003)
Hematology
, pp. 132-152
-
-
Melo, J.V.1
Hughes, T.P.2
Apperley, J.F.3
-
18
-
-
2542500611
-
The biology of CML blast crisis
-
Calabretta B, Perrotti D (2004) The biology of CML blast crisis. Blood 103: 4010-4022.
-
(2004)
Blood
, vol.103
, pp. 4010-4022
-
-
Calabretta, B.1
Perrotti, D.2
-
19
-
-
0036050013
-
Chronic myelogenous leukemia: Mechanisms underlying disease progression
-
Shet AS, Jahagirdar BN, Verfaillie CM (2002) Chronic myelogenous leukemia: mechanisms underlying disease progression. Leukemia 16: 1402-1411.
-
(2002)
Leukemia
, vol.16
, pp. 1402-1411
-
-
Shet, A.S.1
Jahagirdar, B.N.2
Verfaillie, C.M.3
-
20
-
-
3042606424
-
Biology of chronic myeloid leukemia and possible therapeutic approaches to imatinib-resistant disease
-
Yoshida C, Melo JV (2004) Biology of chronic myeloid leukemia and possible therapeutic approaches to imatinib-resistant disease. Int J Hematol 79: 420-433.
-
(2004)
Int J Hematol
, vol.79
, pp. 420-433
-
-
Yoshida, C.1
Melo, J.V.2
-
21
-
-
0033614446
-
Chronic myeloid leukemia
-
Sawyers CL (1999) Chronic myeloid leukemia. N Engl J Med 340: 1330-1340.
-
(1999)
N Engl J Med
, vol.340
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
22
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, Hsu N, Paquette R, et al. (2001) Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 293: 876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
Hsu, N.4
Paquette, R.5
-
23
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah NP, Tran C, Lee FY, Chen P, Norris D, et al. (2004) Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305: 399-401.
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
-
24
-
-
0037762630
-
Towards combination target-directed chemotherapy for chronic myeloid leukemia: Role of farnesyl cransferase inhibitors
-
Daley GQ (2003) Towards combination target-directed chemotherapy for chronic myeloid leukemia: role of farnesyl cransferase inhibitors. Semin Hematol 40: 11-14.
-
(2003)
Semin Hematol
, vol.40
, pp. 11-14
-
-
Daley, G.Q.1
-
25
-
-
0041466445
-
Specific targeted therapy of chronic myelogenous leukemia with imatinib
-
Deininger MW, Druker BJ (2003) Specific targeted therapy of chronic myelogenous leukemia with imatinib. Pharmacol Rev 55: 401-423.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 401-423
-
-
Deininger, M.W.1
Druker, B.J.2
-
27
-
-
0036179862
-
Recent advancements in the treatment of chronic myelogenous leukemia
-
O'Dwyer ME, Mauro MJ, Druker BJ (2002) Recent advancements in the treatment of chronic myelogenous leukemia. Annu Rev Med 53: 369-381.
-
(2002)
Annu Rev Med
, vol.53
, pp. 369-381
-
-
O'Dwyer, M.E.1
Mauro, M.J.2
Druker, B.J.3
-
28
-
-
1342343033
-
Molecular mechanisms of resistance of leukemia to imatinib mesylate
-
Tauchi T, Ohyashiki K (2004) Molecular mechanisms of resistance of leukemia to imatinib mesylate. Leuk Res 28 Suppl 1: S39-45.
-
(2004)
Leuk Res
, vol.28
, Issue.SUPPL. 1
-
-
Tauchi, T.1
Ohyashiki, K.2
-
29
-
-
33749524667
-
Dynamic modeling of imatinib-treated chronic myeloid leukemia: Functional insights and clinical implications
-
Roeder I, Horn M, Glauche I, Hochhaus A, Mueller MC, et al. (2006) Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications. Nat Med 12: 1181-1184.
-
(2006)
Nat Med
, vol.12
, pp. 1181-1184
-
-
Roeder, I.1
Horn, M.2
Glauche, I.3
Hochhaus, A.4
Mueller, M.C.5
-
30
-
-
21744462100
-
Dynamics of chronic mycloid leukaemia
-
Michor F, Hughes TP, Iwasa Y, Branford S, Shah NP, et al. (2005) Dynamics of chronic mycloid leukaemia. Nature 435: 1267-1270.
-
(2005)
Nature
, vol.435
, pp. 1267-1270
-
-
Michor, F.1
Hughes, T.P.2
Iwasa, Y.3
Branford, S.4
Shah, N.P.5
-
31
-
-
4644341516
-
Discontinuation of imatinib therapy after achieving a molecular response
-
Cortes J, O'Brien S, Kantarjian H (2004) Discontinuation of imatinib therapy after achieving a molecular response. Blood 104: 2204-2205.
-
(2004)
Blood
, vol.104
, pp. 2204-2205
-
-
Cortes, J.1
O'Brien, S.2
Kantarjian, H.3
-
32
-
-
20844461336
-
Imatinib mesylate-sensifive blast crisis immediately after discontinuation of imatinib mesylate therapy in chronic myelogenous leukemia: Report of two cases
-
Higashi T, Tsukada J, Kato C, Iwashige A, Mizobe T, et al. (2004) Imatinib mesylate-sensifive blast crisis immediately after discontinuation of imatinib mesylate therapy in chronic myelogenous leukemia: report of two cases. Am J Hematol 76: 275-278.
-
(2004)
Am J Hematol
, vol.76
, pp. 275-278
-
-
Higashi, T.1
Tsukada, J.2
Kato, C.3
Iwashige, A.4
Mizobe, T.5
-
33
-
-
41549111300
-
-
Blood
-
Rousselot P, Huguet F, Rea D, Legros L, Cayuela JM, et al. (2006) Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than two years. Blood.
-
(2006)
Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than two years
-
-
Rousselot, P.1
Huguet, F.2
Rea, D.3
Legros, L.4
Cayuela, J.M.5
-
34
-
-
10444280878
-
Strategies to overcome resistance to targeted protein kinase inhibitors
-
Daub H, Specht K, Ullrich A (2004) Strategies to overcome resistance to targeted protein kinase inhibitors. Nat Rev Drug Discov 3: 1001-1010.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 1001-1010
-
-
Daub, H.1
Specht, K.2
Ullrich, A.3
-
35
-
-
0642333844
-
Overcoming resistance to imatinib by combining targeted agents
-
Druker BJ (2003) Overcoming resistance to imatinib by combining targeted agents. Mol Cancer Ther 2: 225-226.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 225-226
-
-
Druker, B.J.1
-
36
-
-
4344623889
-
Imatinib as a paradigm of targeted therapies
-
Druker BJ (2004) Imatinib as a paradigm of targeted therapies. Adv Cancer Res 91: 1-30.
-
(2004)
Adv Cancer Res
, vol.91
, pp. 1-30
-
-
Druker, B.J.1
-
37
-
-
0037315281
-
Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias
-
Gambacorti-Passerini CB, Gunby RH, Piazza R, Galietta A, Rostagno R, et al. (2003) Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet Oncol 4: 75-85.
-
(2003)
Lancet Oncol
, vol.4
, pp. 75-85
-
-
Gambacorti-Passerini, C.B.1
Gunby, R.H.2
Piazza, R.3
Galietta, A.4
Rostagno, R.5
-
38
-
-
0348140591
-
Mechanisms and implications of imatinib resistance mutations in BCR-ABL
-
Nardi V, Azam M, Daley GQ (2004) Mechanisms and implications of imatinib resistance mutations in BCR-ABL. Curr Opin Hematol 11: 35-43.
-
(2004)
Curr Opin Hematol
, vol.11
, pp. 35-43
-
-
Nardi, V.1
Azam, M.2
Daley, G.Q.3
-
39
-
-
0012486364
-
Resistance in the land of molecular cancer therapeutics
-
Shannon KM (2002) Resistance in the land of molecular cancer therapeutics. Cancer Cell 2: 99-102.
-
(2002)
Cancer Cell
, vol.2
, pp. 99-102
-
-
Shannon, K.M.1
-
40
-
-
0037531711
-
Advances in targeted therapy for chronic myeloid leukemia
-
Yee KW, Keating A (2003) Advances in targeted therapy for chronic myeloid leukemia. Expert Rev Anticancer Ther 3: 295-310.
-
(2003)
Expert Rev Anticancer Ther
, vol.3
, pp. 295-310
-
-
Yee, K.W.1
Keating, A.2
-
41
-
-
22144443475
-
Drug resistance in cancer: Principles of emergence and prevention
-
Komarova NL, Wodarz D (2005) Drug resistance in cancer: principles of emergence and prevention. Proc Natl Acad Sci U S A 102: 9714-9719.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9714-9719
-
-
Komarova, N.L.1
Wodarz, D.2
-
42
-
-
33846849302
-
New targeted therapies for chronic myelogenous leukemia: Opportunities to overcome imatinib resistance
-
Jabbour E, Cortes J, O'Brien S, Giles F, Kantarjian H (2007) New targeted therapies for chronic myelogenous leukemia: opportunities to overcome imatinib resistance. Semin Hematol 44: 25-31.
-
(2007)
Semin Hematol
, vol.44
, pp. 25-31
-
-
Jabbour, E.1
Cortes, J.2
O'Brien, S.3
Giles, F.4
Kantarjian, H.5
-
43
-
-
0022871280
-
A stochastic model for the origin and treatment of tumors containing drug-resistant cells
-
Coldman AJ, Goldie JH (1986) A stochastic model for the origin and treatment of tumors containing drug-resistant cells. Bull Math Biol 48: 279-292.
-
(1986)
Bull Math Biol
, vol.48
, pp. 279-292
-
-
Coldman, A.J.1
Goldie, J.H.2
-
44
-
-
38249034676
-
Age-size structure in populations with quiescence
-
Gyllenberg M, Webb GF (1987) Age-size structure in populations with quiescence. Mathematical Biosciences 86: 67-95.
-
(1987)
Mathematical Biosciences
, vol.86
, pp. 67-95
-
-
Gyllenberg, M.1
Webb, G.F.2
-
45
-
-
0024435736
-
Quiescence as an explanation of Gompertzian tumor growth
-
Gyllenberg M, Webb GF (1989) Quiescence as an explanation of Gompertzian tumor growth. Growth Dev Aging 53: 25-33.
-
(1989)
Growth Dev Aging
, vol.53
, pp. 25-33
-
-
Gyllenberg, M.1
Webb, G.F.2
-
46
-
-
0025687227
-
A nonlinear structured population model of tumor growth with quiescence
-
Gyllenberg M, Webb GF (1990) A nonlinear structured population model of tumor growth with quiescence. J Math Biol 28: 671-694.
-
(1990)
J Math Biol
, vol.28
, pp. 671-694
-
-
Gyllenberg, M.1
Webb, G.F.2
|