Involvement of homologous recombination repair after proton-induced DNA damage

Mutagenesis

Volumn 23, Issue 2, 2008, Pages 119-129

  Rostek, C ^a   Turner, E L ^a   Robbins, M ^b   Rightnar, S ^b   Xiao, W ^a   Obenaus, A ^b   Harkness, T A A ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CULTURE; CELL STRESS; CELL SURVIVAL; COSMIC RADIATION; DNA DAMAGE; DNA RECOMBINATION; DNA STRAND BREAKAGE; GAMMA RADIATION; GENE DELETION; GENE MUTATION; GENETIC ANALYSIS; LINEAR ENERGY TRANSFER; PHENOTYPE; PRIORITY JOURNAL; PROTON RADIATION; RADIATION EXPOSURE; RADIOSENSITIVITY; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET IRRADIATION; YEAST CELL; DNA REPAIR; GENETIC RECOMBINATION; GENETICS; MUTATION; PHYSIOLOGY; RADIATION DOSE; ULTRAVIOLET RADIATION;

SACCHAROMYCES CEREVISIAE;

DNA; PROTON; RAD52 PROTEIN;

DNA; DNA BREAKS; DNA REPAIR; GAMMA RAYS; GENE DELETION; MUTATION; PROTONS; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; RADIATION TOLERANCE; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET RAYS;

EID: 41449086614     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gem055     Document Type: Article

References (65)

1. DeAngelis, G., Clowdsley, M. S., Nealy, J. E., Tripathi, R. K. and Wilson, J. W. (2004) Irradiation analysis for manned missions to the Jupiter system. Adv. Space Res., 34, 1392-1403.
2. Chassefiere, E., Bertaux, J. L., Berthelier, J. J., Cabane, M., Ciarletti, V., Durry, G., Forget, F., Hamelin, M., Leblanc, F. and Rochette, P. (2004) MEP (Mars Environment Package): toward a package for studying environmental conditions at the surface of Mars from future lander/rover missions. Adv. Space Res., 34, 1702-1709.
3. Petrov, V. M. (2004) Problems and conception of ensuring irradiation safety during Mars missions. Adv. Space Res., 34, 1451-1454.
4. Durante, M., Snigiryova, G., Akaeva, E., Bogomazova, A., Druzhinin, S., Fedorenko, B., Greco, O., Novitskaya, N., Rubanovich, A. and Obe, G. (2003) Chromosome aberration dosimetry in cosmonauts after single or multiple space flights. Cytogenet. Genome Res., 103, 40-46.
5. Scampoli, P. (2004) Biological effects of accelerated protons. Radiother. Oncol., 73, S130-S133.
6. Lin, Z. W. and Adams, J. H., Jr. (2007) Effects of nuclear cross sections at different energies on the radiation hazard from galactic cosmic rays. Radiat. Res., 167, 330-337.
7. Hellweg, C. E. and Baumstark-Khan, C. (2007) Getting ready for the manned mission to Mars: the astronauts' risk from space radiation. Naturwissenschaften, 94, 517-526.
8. Zhao, Y., Johnsen, R., Baillie, D. and Rose, A. (2005) Worms in space? A model biological dosimeter. Gravit. Space Biol. Bull., 18, 11-16.
9. Hajek, M., Berger, T., Fugger, M., Furstner, M., Vana, N., Akatov, Y., Shurshakov, V. and Arkhangelsky, V. (2006) Dose distribution in the Russian Segment of the International Space Station. Radiat. Prot. Dosimetry, 120, 446-449.
10. Ohnishi, K. and Ohnishi, T. (2004) The biological effects of space irradiation during long stays in space. Biol. Sci. Space, 18, 201-205.
11. Cucinotta, F. A., Kim, M.-H. Y. and Ren, L. (2005) Managing Lunar and Mars Mission Radiation Risks. Part 1: Cancer Risks, Uncertainties, and Sheilding Effectiveness. Nasa, Washington, DC.
12. Nelson, G. A. (2003) Fundamental space radiobiology. Gravit. Space Biol. Bull., 16, 29-36.
13. Borak, T. B., Doke, T., Fuse, T., et al. (2004) Comparisons of LET distributions for protons with energies between 50 and 200 MeV determined using a spherical tissue-equivalent proportional counter (TEPC) and a position-sensitive silicon spectrometer (RRMD-III). Radiat. Res., 162, 687-692.
14. Kao, J., Rosenstein, B. S., Peters, S., Milano, M. T. and Kron, S. J. (2005) Cellular response to DNA damage.. Ann. N. Y. Acad. Sci., 1066, 243-258.
15. Lieberman, H. B. (2006) Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J. Cell Biochem., 97, 690-697.
16. Gialanella, G., Grossi, G. F., Macchiato, M. F., Napolitano, M. and Speranza, P. R. (1983) Contributions of various types of damage to inactivation of T4 bacteriophage by protons. Radiat. Res., 96, 462-475.
17. Frankenberg, D., Brede, H. J., Schrewe, U. J., Steinmetz, C., Frankenberg-Schwager, M., Kasten, G. and Pralle, E. (2000) Induction of DNA double-strand breaks in mammalian cells and yeast. Adv. Space Res., 25, 2085-2094.
18. Hada, M. and Sutherland, B. M. (2006) Spectrum of complex DNA damages depends on the incident radiation. Radiat. Res., 165, 223-230.
19. Kundrat, P. and Stewart, R. D. (2006) On the biophysical interpretation of lethal DNA lesions induced by ionising radiation. Radiat. Prot. Dosimetry, 122, 169-172.
20. Campa, A., Ballarini, F., Belli, M., et al. (2005) DNA DSB induced in human cells by charged particles and gamma rays: experimental results and theoretical approaches. Int. J. Radiat. Biol., 81, 841-854.
21. Friedland, W., Jacob, P., Bernhardt, P., Paretzke, H. G. and Dingfelder, M. (2003) Simulation of DNA damage after proton irradiation. Radiat. Res., 159, 401-410.
22. Goodhead, D. T. (1994) Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int. J. Radiat. Biol., 65, 7-17.
23. Ward, J. F. (1994) The complexity of DNA damage: relevance to biological consequences. Int. J. Radiat. Biol., 66, 427-432.
24. Jakob, B., Scholz, M. and Taucher-Scholz, G. (2003) Biological imaging of heavy charged-particle tracks. Radiat. Res., 159, 676-684.
25. Desai, N., Durante, M., Lin, Z. W., Cucinotta, F. and Wu, H. (2005) High LET-induced H2AX phosphorylation around the Bragg curve. Adv. Space Res., 35, 236-242.
26. Tartier, L., Spenlehauer, C., Newman, H. C., Folkard, M., Prise, K. M., Michael, B. D., Menissier-deMurcia, J. and deMurcia, G. (2003) Local DNA damage by proton microbeam irradiation induces poly(ADP-ribose) synthesis in mammalian cells. Mutagenesis, 18, 411-416.
27. Di Pietro, C., Piro, S., Tabbi, G., et al. (2006) Cellular and molecular effects of protons: apoptosis induction and potential implications for cancer therapy. Apoptosis, 11, 57-66.
28. Fry, R. C., Begley, T. J. and Samson, L. D. (2005) Genome-wide responses to DNA-damaging agents. Annu. Rev. Microbiol., 59, 357-377.
29. Beranek, D. T. (1990) Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res., 231, 11-30.
30. Xiao, W., Chow, B. L. and Rathgeber, L. (1996) The repair of DNA methylation damage in Saccharomyces cerevisiae. Curr. Genet., 30, 461-468.
31. Hanna, M., Chow, B. L., Morey, N. J., Jinks-Robertson, S., Doetsch, P. W. and Xiao, W. (2004) Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. DNA Repair, 3, 51-59.
32. Xiao, W., Chow, B. L., Hanna, M. and Doetsch, P. W. (2001) Deletion of the MAG1 DNA glycosylase gene suppresses alkylation-induced killing and mutagenesis in yeast cells lacking AP endonucleases. Mutat. Res., 487, 137-147.
33. Tanaka, T., Huang, X., Halicka, H. D., Zhao, H., Traganos, F., Albino, A. P., Dai, W. and Darzynkiewicz, Z. (2007) Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents. Cytometry A., 71, 648-661.
34. Broomfield, S., Hryciw, T. and Xiao, W. (2001) DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae. Mutat. Res., 486, 167-184.
35. Krogh, B. O. and Symington, L. S. (2004) Recombination proteins in yeast. Annu. Rev. Genet., 38, 233-271.
36. Dudasova, Z., Dudas, A. and Chovanec, M. (2004) Non-homologous end-joining factors of Saccharomyces cerevisiae. FEMS Microbiol. Rev., 28, 581-601.
37. Lewis, L. K. and Resnick, M. A. (2000) Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae. Mutat. Res., 451, 71-89.
38. Ianzini, F., Cherubini, R. and Mackey, M. A. (1999) Mitotic catastrophe induced by exposure of V79 Chinese hamster cells to low-energy protons. Int. J. Radiat. Biol., 75, 717-723.
39. Antoccia, A., Sgura, A., Cavinato, M., Cherubini, R. and Tanzarella, C. (2002) Cell cycle perturbations and cytogenetic damage induced by low energy protons in human primary fibroblasts. Radiat. Prot. Dosimetry, 99, 197-198.
40. Belli, M., Cherubini, R., Dalla Vecchia, M., Dini, V., Esposito, G., Moschini, G., Sapora, O., Signoretti, C., Simone, G. and Tabocchini, M. A. (2001) DNA fragmentation in mammalian cells exposed to various light ions. Adv. Space Res., 27, 393-399.
41. Belli, M., Cherubini, R., Dalla Vecchia, M., Dini, V., Esposito, G., Moschini, G., Sapora, O., Simone, G. and Tabocchini, M. A. (2002) DNA fragmentation in V79 cells irradiated with light ions as measured by pulsed-field gel electrophoresis. I. Experimental results. Int. J. Radiat. Biol., 78, 475-482.
42. Adzuma, K., Ogawa, T. and Ogawa, H. (1984) Primary structure of the RAD52 gene in Saccharomyces cerevisiae. Mol. Cell. Biol., 4, 2735-2744.
43. Leloup, C., Garty, G., Assaf, G., et al. (2005) Evaluation of lesion clustering in irradiated plasmid DNA. Int. J. Radiat. Biol., 81, 41-54.
44. Harkness, T. A. A., Davies, G. F., Ramaswamy, V. and Arnason, T. G. (2002) The ubiquitin-dependent targeting pathway in Saccharomyces cerevisiae plays a critical role in multiple chromatin assembly regulatory steps. Genetics, 162, 615-632.
45. Latif, C., Elzen, N. R. and O'Connell, M. J. (2004) DNA damage checkpoint maintenance through sustained Chk1 activity. J. Cell Sci., 117, 3489-3498.
46. Snow, R. (1967) Mutants of yeast sensitive to ultraviolet light. J. Bacteriol., 94, 571-575.
47. Nakai, S. and Matsumoto, S. (1967) Two types of radiation-sensitive mutant in yeast. Mutat. Res., 4, 129-136.
48. Cox, B. S. and Parry, J. M. (1968) The isolation, genetics and survival characteristics of ultraviolet light-sensitive mutants in yeast. Mutat. Res., 6, 37-55.
49. Resnick, M. A. (1969) Induction of mutations in Saccharomyces cerevisiae by ultraviolet light. Mutat. Res., 7, 315-332.
50. Game, J. C. and Mortimer, R. K. (1974) A genetic study of x-ray sensitive mutants in yeast. Mutat. Res., 24, 281-292.
51. Moore, C. W. (1978) Responses of radiation-sensitive mutants of Saccharomyces cerevisiae to lethal effects of bleomycin. Mutat. Res., 51, 165-180.
52. Geigl, E. M. and Eckardt-Schupp, F. (1991) Repair of gamma ray-induced S1 nuclease hypersensitive sites in yeast depends on homologous mitotic recombination and a RAD18-dependent function. Curr. Genet., 20, 33-37.
53. Krogh, B. O. and Symington, L. S. (2004) Recombination proteins in yeast. Annu. Rev. Genet., 38, 233-271.
54. Kiefer, J., Egenolf, R. and Ikpeme, S. (2002) Heavy ion-induced DNA double-strand breaks in yeast. Radiat. Res., 157, 141-148.
55. Yamashita, Y. M., Okada, T., Matsusaka, T., Sonoda, E., Zhao, G. Y., Araki, K., Tateishi, S., Yamaizumi, M. and Takeda, S. (2002) RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells. EMBO J., 21, 5558-5566.
56. Sonoda, E., Hochegger, H., Saberi, A., Taniguchi, Y. and Takeda, S. (2006) Differential usage of non-homologous end-joining and homologous recombination in double strand break repair. DNA Repair, 5, 1021-1029.
57. Symington, L. S. (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol. Mol. Biol. Rev., 66, 630-670.
58. Zou, H. and Rothstein, R. (1997) Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism. Cell, 90, 87-96.
59. McKee, R. H. and Lawrence, C. W. (1979) Genetic analysis of gamma-ray mutagenesis in yeast. I. Reversion in radiation-sensitive strains. Genetics, 93, 361-373.
60. von Borstel, R. C., Cain, K. T. and Steinberg, C. M. (1971) Inheritance of spontaneous mutability in yeast. Genetics, 69, 17-27.
61. Quah, S. K., von Borstel, R. C. and Hastings, P. J. (1980) The origin of spontaneous mutation in Saccharomyces cerevisiae. Genetics, 96, 819-839.
62. Roche, H., Gietz, R. D. and Kunz, B. A. (1995) Specificities of the Saccharomyces cerevisiae rad6, rad18, and rad52 mutators exhibit different degrees of dependence on the REV3 gene product, a putative nonessential DNA polymerase. Genetics, 140, 443-456.
63. Huang, M. E., de Calignon, A., Nicolas, A. and Galibert, F. (2000) POL32, a subunit of the Saccharomyces cerevisiae DNA polymerase delta, defines a link between DNA replication and the mutagenic bypass repair pathway. Curr. Genet., 38, 178-187.
64. Aboussekhra, A., Chanet, R., Zgaga, Z., Cassier-Chauvat, C., Heude, M. and Fabre, F. (1989) RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene. Nucleic Acids Res., 17, 7211-7219.
65. Stelter, P. and Ulrich, H. D. (2003) Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature, 425, 188-191.