Spectrum of complex DNA damages depends on the incident radiation

Radiation Research

Volumn 165, Issue 2, 2006, Pages 223-230

  Hada, Megumi ^a,b   Sutherland, Betsy M ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b UNIVERSITIES SPACE RESEARCH ASSOCIATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARBON; DNA BASE; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; DOUBLE STRANDED DNA; GENOMIC DNA; IRON; NFO PROTEIN; PROTON; PURINE; SILICON; TITANIUM; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ELECTRONIC IMAGING; ESCHERICHIA COLI; GEL ELECTROPHORESIS; IMAGING; IONIZING RADIATION; LINEAR ENERGY TRANSFER; MOLECULAR SIZE; NONHUMAN; NUCLEON; OXIDATION; PHOTON; PRIORITY JOURNAL; SURFACE CHARGE;

BACTERIOPHAGE T7; DNA DAMAGE; DNA, VIRAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; HEAVY IONS; LINEAR ENERGY TRANSFER; PROTONS; RADIATION DOSAGE; RADIATION, IONIZING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 31444445899     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR3498.1     Document Type: Article

References (37)

1. K. M. Prise, C. H. Pullar and B. D. Michael, A study of endonuclease Ill-sensitive sites in irradiated DNA: Detection of alpha-particle-induced oxidative damage. Carcinogenesis 20, 905-909 (1999).
2. J. Milligan, J. Aguilera, T. Nguyen, R. Paglinawan and J. Ward, DNA strand-break yields after post-irradiation incubation with base excision repair endonucleascs implicate hydroxyl radical pairs in double-strand break formation. Int. J. Radiat. Biol. 76, 1475-1483 (2000).
3. B. M. Sutherland, P. V. Bennett, O. Sidorkina and J. Laval, DNA damage clusters induced by ionizing radiation in isolated DNA and in human cells. Proc. Natl. Acad. Sci. USA 97, 103-108 (2000).
4. M. A. Chaudhry and M. Weinfeld. Reactivity of human apurinic/apyrimidinic endonuclease and Excherichia coli exonuclease III with bistranded abasic sites in DNA. J. Biol. Chem. 272, 15650-15655 (1997).
5. M. H. David-Cordonnier, S. M. Cunniffe, I. D. Hickson and P. O'Neill, Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease. Biochemistry 41, 634-642 (2002).
6. L. Harrison, Z. Hatahet and S. Wallace, In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. J. Mol. Biol. 290, 667-684 (1999).
7. A. G. Georgakilas, P. V. Bennett, D. M. Wilson, 3rd and B. M. Sutherland, Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells. Nucleic Acids Res. 32, 5609-5620 (2004).
8. B. M. Sutherland, P. V. Bennett, E. Weinert, O. Sidorkina and J. Laval, Frequencies and relative levels of clustered damages in DNA exposed to gamma rays in radioquenching vs. nonradioquenching conditions. Environ. Mol. Mutagen. 38, 159-165 (2001).
9. T. C. Akpa, K. J. Weber, E. Schneider, J. Kiefer, M. Frankenberg- Schwager, R. Harbich and D. Frankenberg, Heavy ion-induced DNA double-strand breaks in yeast. Int. J. Radiat. Biol. 62, 279-287 (1992).
10. K. M. Prise, G. Ahnstrom, M. Belli, J. Carlsson, D. Frankenberg, J. Kiefer, M. Lobrich, B. D. Michael, J. Nygren, G. Simone and B. Stenerlow, A review of dsb induction data for varying quality radiation. Int. J. Radiat. Biol. 74, 173-184 (1998).
11. G. Taucher-Scholz and G. Kraft, Influence of radiation quality on the yield of DNA strand breaks in SV40 DNA irradiated in solution. Radiat. Res. 151, 595-604 (1999).
12. J. P. Pouget, S. Frelon, J. L. Ravanat, I. Testard, F. Odin and J. Cadet, Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles. Radiat. Res. 157, 589-595 (2002).
13. J. R. Milligan, J. A. Aguilera, R. A. Paglinawan, J. F. Ward and C. L. Limoli, DNA strand break yields after post-high LET irradiation incubation with endonuclease-III and evidence for hydroxyl radical clustering. Int. J. Radiat. Biol. 77, 155-164 (2001).
14. B. M. Sutherland, P. V. Bennett, N. S. Cintron, P. Guida and J. Laval, Low levels of endogenous oxidative damage cluster levels in unirradiated viral and human DNAs. Free Radic. Biol. Med. 35, 495-503 (2003).
15. 137Cs gamma rays. Radiat. Res. 155, 269-278 (2001).
16. M. Haring, H. Rudiger, B. Demple, S. Boiteux and B. Epe, Recognition of oxidized abasic sites by repair endonucleases. Nucleic Acids Res. 22, 2010-2015 (1994).
17. S. Ljungquist, A new endonuclease from Escherichia coli acting at apurinic sites in DNA. J. Biol. Chem. 252, 2808-2814 (1977).
18. J. D. Levin, A. W. Johnson and B. Demple, Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA. J. Biol. Chem. 263, 8066-8071 (1988).
19. M. Takeuchi, B. Demple and M. Takeshita, Interactions of Escherichia coli endonuclease IV and exonuclease III with abasic sites in DNA. J. Biol. Chem. 26, 21907-21914 (1994).
20. H. Ide, K. Tedzuka, H. Shimzu, Y. Kumura, A. A. Purmal, S. S. Wallace and Y. W. Kow, α-Deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV. Biochemistry 33, 7842-7847 (1994).
21. A. A. Ischenko and M. K. Saparbaev, Alternative nucleotide incision repair pathway for oxidative DNA damage. Nature 415, 183-187 (2002).
22. S. Boiteux, T. R. O'Connor, F. Lederer, A. Gouyette and J. Laval. Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites. J. Biol. Chem. 265, 3916-3922 (1990).
23. S. Boiteux, E. Gajewski, J. Laval and M. Dizdaroglu, Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 31, 106-110 (1992).
24. J. Tchou, H. Kasai, S. Shibutani, M-H. Chung, J. Laval, A. P. Grollman and S. Nishimura, 8-Oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity. Proc. Natl. Acad. Sci. USA 88, 4690-4694 (1991).
25. A. Hatahet, W. Y. Kow, A. A. Purmal, R. P. Cunningham and S. S. Wallace, New substrates for old enzymes. 5-hydroxy-2′-deoxycytidine and 5-hydroxy-2′-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase. while 5-hydroxy-2′- deoxyuridine is a substrate for uracil DNA N-glycosylase. J. Biol. Chem. 269, 18814-18820 (1994).
26. J. Jurado, M. Saparbaev, T. J. Matray, M. M. Greenberg and J. Laval, The ring fragmentation product of thymidine C5-hydrate when present in DNA is repaired by the Escherichia coli Fpg and Nth proteins. Biochemistry 37, 7757-7763 (1998).
27. J. C. Sutherland, D. C. Monteleone, J. H. Mugavero and J. Trunk, Unidirectional pulsed-field electrophoresis of single- and double-stranded DNA in agarose gels: Analytical expression relating mobility and molecular length and their application in the measurement of strand breaks. Anal. Biochem. 162, 511-520 (1987).
28. J. C. Sutherland, B. Lin, D. C. Monteleone, J. Mugavero, B. M. Sutherland and J. Trunk. Electronic imaging system for direct and rapid quantitation of fluorescence from electrophoretic gels: Application to ethidium bromide-stained DNA. Anal. Biochem. 163, 446-457 (1987).
29. J. C. Sutherland, D. C. Monteleone, J. G. Trunk, P. V. Bennett and B. M. Sutherland. Quantifying DNA damage by gel electrophoresis, electronic Imaging and number average length analysis. Electrophoresis 22, 843-854 (2001).
30. B. M. Sutherland, P. V. Bennett, A. G. Georgakilas and J. C. Sutherland, Evaluation of number average length analysis in quantifying double strand breaks in genomic DNAs. Biochemistry 42, 3375-3384 (2003).
31. R. Roots, W. Holley, A. Chatterjee, M. Irizarry and G. Kraft, The formation of strand breaks in DNA after high-LET irradiation: A comparison of data from in vitro and cellular systems. Int. J. Radiat. Biol. 58, 55-69 (1990).
32. W. Friedland, P. Jacob, P. Bernhardt, H. G. Paretzke and M. Dingfelder, Simulation of DNA damage after proton irradiation. Radiat. Res. 159, 401-410 (2003).
33. W. Friedland, M. Dingfelder, P. Jacob and H. G. Paretzke, Calculated DNA double-strand break and fragmentation yields after irradiation with He ions. Radiat. Phys. Chem. 72, 279-286 (2005).
34. 4He ions in primary human skin fibroblasts in the LET range of 8 to 124 keV/μm. Radiat. Res. 151, 540-549 (1999).
35. T. Moritake, K. Tsuboi, K. Anzai, T. Ozawa, K. Ando and T. Nose, ESR spin trapping of hydroxyl radicals in aqueous solution irradiated with high-LET carbon-ion beams. Radiat. Res. 159, 670-675 (2003).
36. H. Nikjoo, P. O'Neill, D. T. Goodhead and M. Terrissol, Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events. Int. J. Radiat. Biol. 71, 467-483 (1997).
37. F. A. Cucinotta, H. Nikjoo and D. T. Goodhead, Model for radial dependence of frequency distributions for energy imparted in nanometer volumes from HZE particles. Radiat. Res. 153, 459-468 (2000).